@article{PastekaForjanSauermannetal., author = {Pasteka, Richard and Forjan, Mathias and Sauermann, Stefan and Drauschke, Andreas}, title = {Electro-mechanical Lung Simulator Using Polymer and Organic Human Lung Equivalents for Realistic Breathing Simulation}, series = {Scientific Reports}, volume = {Vol 9}, journal = {Scientific Reports}, number = {No. 1}, pages = {Article number: 19778}, abstract = {Simulation models in respiratory research are increasingly used for medical product development and testing, especially because in-vivo models are coupled with a high degree of complexity and ethical concerns. This work introduces a respiratory simulation system, which is bridging the gap between the complex, real anatomical environment and the safe, cost-effective simulation methods. The presented electro-mechanical lung simulator, xPULM, combines in-silico, ex-vivo and mechanical respiratory approaches by realistically replicating an actively breathing human lung. The reproducibility of sinusoidal breathing simulations with xPULM was verified for selected breathing frequencies (10-18 bpm) and tidal volumes (400-600 ml) physiologically occurring during human breathing at rest. Human lung anatomy was modelled using latex bags and primed porcine lungs. High reproducibility of flow and pressure characteristics was shown by evaluating breathing cycles (nTotal = 3273) with highest standard deviation |3σ| for both, simplified lung equivalents (μV˙ = 23.98 ± 1.04 l/min, μP = -0.78 ± 0.63 hPa) and primed porcine lungs (μV˙ = 18.87 ± 2.49 l/min, μP = -21.13 ± 1.47 hPa). The adaptability of the breathing simulation parameters, coupled with the use of porcine lungs salvaged from a slaughterhouse process, represents an advancement towards anatomically and physiologically realistic modelling of human respiration.}, subject = {Breathing Simulation}, language = {en} } @article{TraxlerBayerReuttereretal., author = {Traxler, Lukas and Bayer, Natascha and Reutterer, Bernd and Drauschke, Andreas and Husinsky, Wolfgang}, title = {Pr{\"u}fung der optischen Qualit{\"a}t von Intraokularlinsen auf Tolerant gegen{\"u}ber Fehlplatzierungen im Auge}, series = {Proceedings der Jahrestagung der {\"O}sterreichischen Gesellschaft f{\"u}r Biomedizinische Technik ({\"O}GBMT) 2015}, journal = {Proceedings der Jahrestagung der {\"O}sterreichischen Gesellschaft f{\"u}r Biomedizinische Technik ({\"O}GBMT) 2015}, subject = {Eye Lens}, language = {de} } @article{BayerHirnschallTraxleretal., author = {Bayer, Natascha and Hirnschall, Nino and Traxler, Lukas and Drauschke, Andreas and Find, Oliver}, title = {Analysis of customized ocular data and wave front aberrations concerning their deviations from generic eye models}, series = {Proceedings der Dreil{\"a}ndertagung der biomedizinischen Technik (BMT)}, journal = {Proceedings der Dreil{\"a}ndertagung der biomedizinischen Technik (BMT)}, subject = {Mechanical Eye}, language = {en} }