@misc{Drauschke, author = {Drauschke, Andreas}, title = {Applications of Optogenetics}, subject = {Optogenetics}, language = {en} } @inproceedings{Drauschke, author = {Drauschke, Andreas}, title = {Comparison of Numerical Eye Models and its Representation within a Mechanical Eye Model}, series = {IFAC-Papers Online}, booktitle = {IFAC-Papers Online}, pages = {133 -- 138}, subject = {Mechanical Eye}, language = {en} } @misc{Drauschke, author = {Drauschke, Andreas}, title = {Comparison of Numerical Eye Models and its Representation within a Mechanical Eye Model}, subject = {Mechanical Eye}, language = {en} } @inproceedings{PastekaForjanDrauschke, author = {Pasteka, Richard and Forjan, Mathias and Drauschke, Andreas}, title = {Comparison of Mathematical and Controlled Mechanical Lung Simulation in Active Breathing and Ventilated State}, series = {Proceedings of the 15th IFAC Conference on Programmable Devices and Embedded Systems PDeS 2018}, booktitle = {Proceedings of the 15th IFAC Conference on Programmable Devices and Embedded Systems PDeS 2018}, subject = {Breathing Simulation}, language = {en} } @inproceedings{SteinerForjanKoppetal., author = {Steiner, Theresa and Forjan, Mathias and Kopp, Tamara and Bures, Zbyn{\^e}k and Drauschke, Andreas}, title = {Enhancements of a mechanical lung simulator for ex vivo measuring of aerosol deposition in lungs}, series = {Proceedings of the 46th annual conference of the German Society for Biomedical Engineering}, booktitle = {Proceedings of the 46th annual conference of the German Society for Biomedical Engineering}, pages = {838 -- 841}, subject = {Lung Simulator}, language = {en} } @article{PastekaForjanSauermannetal., author = {Pasteka, Richard and Forjan, Mathias and Sauermann, Stefan and Drauschke, Andreas}, title = {Electro-mechanical Lung Simulator Using Polymer and Organic Human Lung Equivalents for Realistic Breathing Simulation}, series = {Scientific Reports}, volume = {Vol 9}, journal = {Scientific Reports}, number = {No. 1}, pages = {Article number: 19778}, abstract = {Simulation models in respiratory research are increasingly used for medical product development and testing, especially because in-vivo models are coupled with a high degree of complexity and ethical concerns. This work introduces a respiratory simulation system, which is bridging the gap between the complex, real anatomical environment and the safe, cost-effective simulation methods. The presented electro-mechanical lung simulator, xPULM, combines in-silico, ex-vivo and mechanical respiratory approaches by realistically replicating an actively breathing human lung. The reproducibility of sinusoidal breathing simulations with xPULM was verified for selected breathing frequencies (10-18 bpm) and tidal volumes (400-600 ml) physiologically occurring during human breathing at rest. Human lung anatomy was modelled using latex bags and primed porcine lungs. High reproducibility of flow and pressure characteristics was shown by evaluating breathing cycles (nTotal = 3273) with highest standard deviation |3σ| for both, simplified lung equivalents (μV˙ = 23.98 ± 1.04 l/min, μP = -0.78 ± 0.63 hPa) and primed porcine lungs (μV˙ = 18.87 ± 2.49 l/min, μP = -21.13 ± 1.47 hPa). The adaptability of the breathing simulation parameters, coupled with the use of porcine lungs salvaged from a slaughterhouse process, represents an advancement towards anatomically and physiologically realistic modelling of human respiration.}, subject = {Breathing Simulation}, language = {en} } @misc{PastekaForjanDrauschke, author = {Pasteka, Richard and Forjan, Mathias and Drauschke, Andreas}, title = {Comparison of Mathematical and Controlled Mechanical Lung Simulation in Active Breathing and Ventilated State}, subject = {Breathing Simulation}, language = {en} } @misc{PastekaForjanDrauschke, author = {Pasteka, Richard and Forjan, Mathias and Drauschke, Andreas}, title = {Comparison of breathing patterns for aerosol inhalation using an electro-mechanical lung simulator}, series = {ALTEX Proceedings - EUSAAT 2018, Linz}, journal = {ALTEX Proceedings - EUSAAT 2018, Linz}, subject = {Biomedical Engineering}, language = {en} } @misc{ForjanPastekaDrauschke, author = {Forjan, Mathias and Pasteka, Richard and Drauschke, Andreas}, title = {Lung simulation - an alterna� tive approach to animal testing for applications in aerosol and respiratory research}, series = {ALTEX Proceedings - EUSAAT 2018, Linz}, journal = {ALTEX Proceedings - EUSAAT 2018, Linz}, subject = {Biomedical Engineering}, language = {en} } @inproceedings{ReuttererTraxlerBayeretal., author = {Reutterer, Bernd and Traxler, Lukas and Bayer, Natascha and Drauschke, Andreas}, title = {Further improvement of an intraocular lens holder for more physiological measurements within a mechanical eye model}, series = {Proc.SPIE Biomedical Imaging and Sensing Conference}, booktitle = {Proc.SPIE Biomedical Imaging and Sensing Conference}, subject = {Mechanical Eye}, language = {en} }