@article{SimboeckMarksteinerMachaceketal.,
  author    = {Simb{\"o}ck, Elisabeth and Marksteiner, Jessica and Machacek, Thomas and Wiessner, Katharina and Gepp, Barbara and Jesenberger, Veronika and Weihs, Anna and Leitner, Rita},
  title     = {The Power of Problem Based Learning beyond its Didactic Attributes},
  series = {Journal of Problem Based Learning in Higher Education (JPBLHE)},
  volume    = {9},
  journal   = {Journal of Problem Based Learning in Higher Education (JPBLHE)},
  number    = {1},
  pages     = {109 -- 130},
  abstract  = {Hybrid courses with a focus on practice-orientated education and self-guided learning phases are on the rise on the higher education sector. Disciplines in Life Sciences implicate a high degree of practical laboratory expertise. The University of Applied Sciences (UAS) in Vienna, Austria, has thus been endeavoured offering students a high qualitative education integrating hybrid courses based on PBL principles, which consist of on-site (including the transmission of necessary background and practical laboratory training) and off-site (including self-study phases) sessions. As practical laboratory units are central in those courses, the restrictive measures, including the transition to a complete online teaching format due to the first Covid-19-pandemic lock-down, had severe effects on the implementation and the quality of the curriculum. According to surveys made specifically to address this problematic situation, it can be concluded that on-site practical units are fundamental for certain disciplines such as Life Sciences.},
  subject      = {Problem-based Learning},
  language  = {en}
}
@inproceedings{WiessnerPraherLiousiaetal.,
  author    = {Wießner, Katharina and Praher, Daniela and Liousia, Varvara and Gepp, Barbara and Leitner, Rita and R{\"u}nzler, Dominik},
  title     = {Testing the acute toxicity of an alternative to Glyphosate - Pelargonic acid},
  series = {SETAC Europe 30th Annual Meeting - Online},
  booktitle = {SETAC Europe 30th Annual Meeting - Online},
  organization    = {Society of Environmental Toxicology and Chemistry (SETAC)},
  abstract  = {Glyphosate-based herbicides were used as plant protection product globally for several decades. However, glyphosate is discussed as showing genotoxicity and many other side-effects such as inhibiting the mitochondrial succinate dehydrogenase, leading to a decreased ATP production. Therefore, finding alternative active substances is necessary. Pelargonic acid (nonanoic acid) and its ammonium salt (saponified form), which are used as alternatives to glyphosate-based herbicides, are biological derived substances considered as environmentally friendly herbicides. To test the effects of pelargonic acid in its acidic form (active substance in TopGun) and its saponified form (in Finalsan Plus) on the aquatic ecosystem, students of the master study program "environmental management and ecotoxicology" compared the toxicity levels of these substances using zebrafish embryos within the scope of a student research course. The project was developed by applying the 7-step problem-based learning method which allowed the students to design their experiments independently with the guidance and feedback of the lecturers. Acute toxicity was determined according to OECD test guideline 236 in D. rerio which revealed a LC50 of 1.55 mg/L of pelargonic acid, a LC50 value of 0.93 mg/L pelargonic acid in TopGun and a LC50 of 36.37 mg/L of Finalsan Plus. Neutral Red Uptake assays were performed on the rainbow trout-derived gill cell-line RTgill-W1 to determine the acute toxicity according to the OECD test guideline 129 which revealed the IC50 value of 12.4 mg/L pelargonic acid in TG. Due to solubility limits, no reliable IC50 could be obtained. The results of the tests indicate differences in the acute toxicity of the pelargonic acid-based formulations TopGun and Finalsan Plus. However, more investigations have to be done in order to analyse if the acidic form is more toxic than the saponified form. Furthermore, detailed ecotoxicological risk assessments and an evaluation of the genotoxicity of both herbicides has to be performed before any conclusion can be drawn. Financial support from the City of Vienna project PBL in Molecular Life Science (21-06) is gratefully acknowledged.},
  subject      = {Environmental Chemistry},
  language  = {en}
}
@inproceedings{LeitnerGeppLiousiaetal.,
  author    = {Leitner, Rita and Gepp, Barbara and Liousia, Varvara and R{\"u}nzler, Dominik},
  title     = {Teaching 3R principles in ecotoxicology by performing a problem-based learning project},
  series = {ALTEX Proceedings, LINZ 2018 - EUSAAT 2018, Volume 7, No. 2, ISSN 2194-0479 (2018)},
  booktitle = {ALTEX Proceedings, LINZ 2018 - EUSAAT 2018, Volume 7, No. 2, ISSN 2194-0479 (2018)},
  subject      = {Problem Based Learning},
  language  = {en}
}
@misc{GeppLiousiaMachaceketal.,
  author    = {Gepp, Barbara and Liousia, Varvara and Machacek, Thomas and Praher, Daniela and Eisner, Katharina and Limbeck, Sophie and Gamper, Janine and Schwarzl, Elisabeth and Hazod, Till and Landwehr, Renate and Wenger, Charlotte and Olscher, Christoph and Leitner, Rita and R{\"u}nzler, Dominik},
  title     = {Pelargonic acid - an alternative to glyphosate-based herbicides?},
  subject      = {Ecotoxicology},
  language  = {en}
}
@misc{EisnerGeppSchneggetal.,
  author    = {Eisner, Katharina and Gepp, Barbara and Schnegg, Raimund and Dallinger, Reinhard and R{\"u}nzler, Dominik},
  title     = {Investigation of endocrine effects of sublethal cadmium doses on the reproduction system of the freshwater snail B. glabrata},
  subject      = {Ecotoxicology},
  language  = {en}
}
@misc{StoiberPurtscherGeppetal.,
  author    = {Stoiber, Stefan and Purtscher, Michaela and Gepp, Barbara and Huber-Gries, Carina},
  title     = {Towards a platform for spatially defined cell characterization of a miniturized heart tissue model},
  subject      = {Microfluidic},
  language  = {en}
}
@misc{FriedrichLakicPraehauseretal.,
  author    = {Friedrich, Robin and Lakic, Nevana and Pr{\"a}hauser, Linda and Schweitzer, Karoline and Olscher, Christoph and Monforte Vila, Xavier and Leitner, Rita and Gepp, Barbara},
  title     = {Effects of Plastic on the Freshwater Snail Biomphalaria Glabrata},
  series = {SETAC Europe 32nd Annual Meeting in Copenhagen, Denmark from 15 - 19. May 2022},
  journal   = {SETAC Europe 32nd Annual Meeting in Copenhagen, Denmark from 15 - 19. May 2022},
  subject      = {Ecotoxicology},
  language  = {en}
}
@article{XuGeppLenggeretal.,
  author    = {Xu, Yingyang and Gepp, Barbara and Lengger, Nina and Yin, Jia and Breiteneder, Heimo},
  title     = {Identification of probable pectinesterase as a major allergen of pollen of the Asian white birch (Betula platyphylla) in northern China},
  series = {Asian Pac J Allergy Immunol},
  journal   = {Asian Pac J Allergy Immunol},
  doi       = {10.12932/AP-100722-1409},
  subject      = {birch pollen allergy},
  language  = {en}
}