@inproceedings{WiessnerPraherLiousiaetal.,
  author    = {Wießner, Katharina and Praher, Daniela and Liousia, Varvara and Gepp, Barbara and Leitner, Rita and R{\"u}nzler, Dominik},
  title     = {Testing the acute toxicity of an alternative to Glyphosate - Pelargonic acid},
  series = {SETAC Europe 30th Annual Meeting - Online},
  booktitle = {SETAC Europe 30th Annual Meeting - Online},
  organization    = {Society of Environmental Toxicology and Chemistry (SETAC)},
  abstract  = {Glyphosate-based herbicides were used as plant protection product globally for several decades. However, glyphosate is discussed as showing genotoxicity and many other side-effects such as inhibiting the mitochondrial succinate dehydrogenase, leading to a decreased ATP production. Therefore, finding alternative active substances is necessary. Pelargonic acid (nonanoic acid) and its ammonium salt (saponified form), which are used as alternatives to glyphosate-based herbicides, are biological derived substances considered as environmentally friendly herbicides. To test the effects of pelargonic acid in its acidic form (active substance in TopGun) and its saponified form (in Finalsan Plus) on the aquatic ecosystem, students of the master study program "environmental management and ecotoxicology" compared the toxicity levels of these substances using zebrafish embryos within the scope of a student research course. The project was developed by applying the 7-step problem-based learning method which allowed the students to design their experiments independently with the guidance and feedback of the lecturers. Acute toxicity was determined according to OECD test guideline 236 in D. rerio which revealed a LC50 of 1.55 mg/L of pelargonic acid, a LC50 value of 0.93 mg/L pelargonic acid in TopGun and a LC50 of 36.37 mg/L of Finalsan Plus. Neutral Red Uptake assays were performed on the rainbow trout-derived gill cell-line RTgill-W1 to determine the acute toxicity according to the OECD test guideline 129 which revealed the IC50 value of 12.4 mg/L pelargonic acid in TG. Due to solubility limits, no reliable IC50 could be obtained. The results of the tests indicate differences in the acute toxicity of the pelargonic acid-based formulations TopGun and Finalsan Plus. However, more investigations have to be done in order to analyse if the acidic form is more toxic than the saponified form. Furthermore, detailed ecotoxicological risk assessments and an evaluation of the genotoxicity of both herbicides has to be performed before any conclusion can be drawn. Financial support from the City of Vienna project PBL in Molecular Life Science (21-06) is gratefully acknowledged.},
  subject      = {Environmental Chemistry},
  language  = {en}
}
@inproceedings{LeitnerGeppLiousiaetal.,
  author    = {Leitner, Rita and Gepp, Barbara and Liousia, Varvara and R{\"u}nzler, Dominik},
  title     = {Teaching 3R principles in ecotoxicology by performing a problem-based learning project},
  series = {ALTEX Proceedings, LINZ 2018 - EUSAAT 2018, Volume 7, No. 2, ISSN 2194-0479 (2018)},
  booktitle = {ALTEX Proceedings, LINZ 2018 - EUSAAT 2018, Volume 7, No. 2, ISSN 2194-0479 (2018)},
  subject      = {Problem Based Learning},
  language  = {en}
}
@inproceedings{FuchsWeihsSzwarcetal.,
  author    = {Fuchs, Christiane and Weihs, Anna and Szwarc, Dorota and Mittermayr, Rainer and R{\"u}nzler, Dominik and Teuschl, Andreas},
  title     = {Shock wave treatment of muscle (stem) cells - a new implementation for regeneration},
  series = {Proceedings of the 20th International Congress of the ISMST},
  booktitle = {Proceedings of the 20th International Congress of the ISMST},
  subject      = {Shockwave treatment},
  language  = {en}
}
@inproceedings{MaleinerHeherTeuschletal.,
  author    = {Maleiner, Babette and Heher, Philipp and Teuschl, Andreas and Redl, Heinz and R{\"u}nzler, Dominik and Fuchs, Christiane},
  title     = {Generation of aligned skeletal muscle-like tissue based on the application of strain to a 3D fibrin scaffold},
  series = {Proceedings of PACT "Designer Cells go Clinical" Symposium},
  booktitle = {Proceedings of PACT "Designer Cells go Clinical" Symposium},
  subject      = {Tissue Generation},
  language  = {en}
}
@inproceedings{FuchsSzwarcWeihsetal.,
  author    = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik},
  title     = {Shock wave treatment of 3D cardiac model systems activates ERK 1/2 signaling pathway and influences cardiomyogenesis},
  series = {Proceedings of PACT "Designer Cells go Clinical" Symposium},
  booktitle = {Proceedings of PACT "Designer Cells go Clinical" Symposium},
  subject      = {Shockwave treatment},
  language  = {en}
}
@inproceedings{FuchsSzwarcWeihsetal.,
  author    = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik},
  title     = {Shock wave treatment of 3D cardiac model systems activates ERK 1/2 signaling pathway and influences cardiomyogenesis},
  series = {Proceedings of LBG Meeting for Health Sciences 2016},
  booktitle = {Proceedings of LBG Meeting for Health Sciences 2016},
  subject      = {Shockwave treatment},
  language  = {en}
}
@inproceedings{FuchsSzwarcWeihsetal.,
  author    = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik},
  title     = {Shock wave treatment positively influences cardiomyogenesis in an energy-dependent manner},
  series = {Proceedings of PACT "Designer Cells go Clinical" Symposium},
  booktitle = {Proceedings of PACT "Designer Cells go Clinical" Symposium},
  subject      = {Shockwave treatment},
  language  = {en}
}
@inproceedings{WeihsKneblRedletal.,
  author    = {Weihs, Anna and Knebl, Gerald and Redl, Heinz and R{\"u}nzler, Dominik},
  title     = {Evaluation of cell migration methods in 3D hydrogels for tissue engineering applications},
  series = {3. Forschungsforum der {\"o}sterreichischen Fachhochschulen / Fachhochschule K{\"a}rnten},
  booktitle = {3. Forschungsforum der {\"o}sterreichischen Fachhochschulen / Fachhochschule K{\"a}rnten},
  isbn      = {978-3-853912850},
  pages     = {490 -- 491},
  subject      = {Cells},
  language  = {en}
}
@inproceedings{KneblWeihsWeingantetal.,
  author    = {Knebl, Gerald and Weihs, Anna and Weingant, Michaela and Steininger, Thomas and Redl, Heinz and R{\"u}nzler, Dominik},
  title     = {Automatisierte Datenauswertung eines Boyden-Mikro-Chemotaxis-Kammer Zell-Migrations Assays.},
  series = {2. Forschungsforum der {\"o}sterreichischen Fachhochschulen},
  booktitle = {2. Forschungsforum der {\"o}sterreichischen Fachhochschulen},
  isbn      = {978-3-8322-7023-0},
  pages     = {412 -- 417},
  subject      = {Cells},
  language  = {de}
}
@inproceedings{RuenzlerKneblPeterbaueretal.,
  author    = {R{\"u}nzler, Dominik and Knebl, Gerald and Peterbauer, A. and Wolbank, Susanne and Morton, Tatjana J. and Redl, Heinz},
  title     = {Darstellung fluoreszenzmarkierter adulter Stammzellen in drei-dimensionaler Zellkultur mittels Konfokaler Laser Scanning Mikroskopie},
  series = {Erstes Forschungsforum der {\"o}sterreichischen Fachhochschulen},
  booktitle = {Erstes Forschungsforum der {\"o}sterreichischen Fachhochschulen},
  pages     = {311 -- 316},
  subject      = {Cells},
  language  = {en}
}
@inproceedings{MilanLoboRuenzlerGaubitzeretal.,
  author    = {Milan-Lobo, Laura and R{\"u}nzler, Dominik and Gaubitzer, Erwin and K{\"o}hler, Gottfried and Bonci, Antonello and Freissmuth, Michael and Sitte, Harald H.},
  title     = {CRF receptors form dynamic complexes at the plasma membrane but only type 2 receptor increases lateral mobility after CRF binding},
  series = {FEBS Journal},
  booktitle = {FEBS Journal},
  subject      = {Plasma Membrane},
  language  = {en}
}
@inproceedings{KaislerPazmandiOrtneretal.,
  author    = {Kaisler, Raphaela and P{\´a}zm{\´a}ndi, Christian and Ortner, Anna and Haberl, Ines and K{\"o}hler, Gottfried and R{\"u}nzler, Dominik and Artl, Andreas and Andreae, Fritz and Mosg{\"o}ller, Wilhelm},
  title     = {Vasoactive intestinal peptide conjugate internalisation as strategy for cytoplasmic drug delivery},
  series = {Journal of Molecular Neuroscience},
  booktitle = {Journal of Molecular Neuroscience},
  subject      = {Cytplasmic Drug Delivery},
  language  = {en}
}
@inproceedings{HuberGriesMollLiuetal.,
  author    = {Huber-Gries, Carina and Moll, Dieter and Liu, Jing and R{\"u}nzler, Dominik and S{\´a}ra, Margit and Sleytr, Uwe},
  title     = {S-layer-streptavidin fusion proteins: Novel Tools in Nanobiotechnology},
  series = {6th Annual Linz Winter Workshop - Book of Abstracts},
  booktitle = {6th Annual Linz Winter Workshop - Book of Abstracts},
  pages     = {11 -- 11},
  subject      = {Proteins},
  language  = {en}
}
@inproceedings{HuberGriesLiuEgelseeretal.,
  author    = {Huber-Gries, Carina and Liu, Jing and Egelseer, Eva-Maria and R{\"u}nzler, Dominik and S{\´a}ra, Margit and Sleytr, Uwe},
  title     = {Application Potential of Bacterial Self-Assembly Systems for Nanobiotechnology},
  series = {Nanobionics III (from Molecules to Applications) Book of Abstracts},
  booktitle = {Nanobionics III (from Molecules to Applications) Book of Abstracts},
  subject      = {Nanotechnology},
  language  = {en}
}
@inproceedings{HuberGriesMollSchlegeletal.,
  author    = {Huber-Gries, Carina and Moll, Dieter and Schlegel, Birgit and R{\"u}nzler, Dominik and Mader, Christoph and S{\´a}ra, Margit and Sleytr, Uwe},
  title     = {Recombinant S-layer-streptavidin fursion proteins: Functional protein lattices as nanoarrays for biochip development},
  series = {Proceedings der 28. Jahrestagung der {\"O}sterreichischen Gesellschaft f{\"u}r Hygiene, Mikrobiologie und Pr{\"a}ventivmedizin, Merano (Italy)},
  booktitle = {Proceedings der 28. Jahrestagung der {\"O}sterreichischen Gesellschaft f{\"u}r Hygiene, Mikrobiologie und Pr{\"a}ventivmedizin, Merano (Italy)},
  subject      = {Proteins},
  language  = {en}
}
@inproceedings{LeebLeitnerPichleretal.,
  author    = {Leeb, Christine and Leitner, Rita and Pichler, Verena and Huber-Gries, Carina and R{\"u}nzler, Dominik and Jesenberger, Veronika},
  title     = {Einf{\"u}hrung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich},
  series = {Proceedings des Kongresses Problem-Based Learning 2016 PBL - Kompetenzen f{\"o}rdern, Zukunft gestalten},
  booktitle = {Proceedings des Kongresses Problem-Based Learning 2016 PBL - Kompetenzen f{\"o}rdern, Zukunft gestalten},
  subject      = {Life Science},
  language  = {de}
}
@inproceedings{HuberGriesMollLiuetal.,
  author    = {Huber-Gries, Carina and Moll, Dieter and Liu, Jing and R{\"u}nzler, Dominik and S{\´a}ra, Margit and Sleytr, Uwe B.},
  title     = {Chimaeric S-Layers as Nanopatterned Biomaterials for Applications in Nanobiotechnology},
  series = {Poster presentation at the 7th Annual Linz Winter Workshop / Book of Abstracts / Linz},
  booktitle = {Poster presentation at the 7th Annual Linz Winter Workshop / Book of Abstracts / Linz},
  pages     = {1 -- 10},
  subject      = {Biomaterial},
  language  = {en}
}
@inproceedings{KneblMortonRedletal.,
  author    = {Knebl, Gerald and Morton, Tatjana J. and Redl, Heinz and R{\"u}nzler, Dominik},
  title     = {Mechanical stimulation of cells in 3-dimensional fibrin constructs using a bioreactor},
  series = {3. Forschungsforum der {\"o}sterreichischen Fachhochschulen / Fachhochschule K{\"a}rnten},
  booktitle = {3. Forschungsforum der {\"o}sterreichischen Fachhochschulen / Fachhochschule K{\"a}rnten},
  pages     = {492 -- 493},
  subject      = {Cells},
  language  = {en}
}