@article{LeebLeitnerPichleretal., author = {Leeb, Christine and Leitner, Rita and Pichler, Verena and Huber-Gries, Carina and R{\"u}nzler, Dominik and Jesenberger, Veronika}, title = {Einf{\"u}hrung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich}, series = {Zeitschrift f{\"u}r Hochschulentwicklung (ZFHE)}, volume = {11}, journal = {Zeitschrift f{\"u}r Hochschulentwicklung (ZFHE)}, number = {3}, pages = {107 -- 121}, subject = {Life Science}, language = {de} } @article{RiederWeihsWeidingeretal., author = {Rieder, Bernhard and Weihs, Anna and Weidinger, Adelheid and Sczwarc, Dorota and N{\"u}rnberger, Sylvia and Redl, Heinz and R{\"u}nzler, Dominik and Huber-Gries, Carina and Teuschl, Andreas}, title = {Hydrostatic pressure-generated reactive oxygen species induce osteoarthritic conditions in cartilage pellet cultures}, series = {Scientific Reports}, journal = {Scientific Reports}, subject = {Bioreactor}, language = {en} } @inproceedings{LeebLeitnerPichleretal., author = {Leeb, Christine and Leitner, Rita and Pichler, Verena and Huber-Gries, Carina and R{\"u}nzler, Dominik and Jesenberger, Veronika}, title = {Einf{\"u}hrung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich}, series = {Proceedings des Kongresses Problem-Based Learning 2016 PBL - Kompetenzen f{\"o}rdern, Zukunft gestalten}, booktitle = {Proceedings des Kongresses Problem-Based Learning 2016 PBL - Kompetenzen f{\"o}rdern, Zukunft gestalten}, subject = {Life Science}, language = {de} } @misc{LeebLeitnerPichleretal., author = {Leeb, Christine and Leitner, Rita and Pichler, Verena and Huber-Gries, Carina and R{\"u}nzler, Dominik and Jesenberger, Veronika}, title = {Einf{\"u}hrung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich}, subject = {Life Science}, language = {de} } @article{PriglingerSchuhSteffenhagenetal., author = {Priglinger, Eleni and Schuh, Christina and Steffenhagen, Carolin and Wurzer, Christoph and Maier, Julia and N{\"u}rnberger, Sylvia and Holnthoner, Wolfgang and Fuchs, Christiane and Suessner, Susanne and R{\"u}nzler, Dominik and Redl, Heinz and Wolbank, Susanne}, title = {Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy.}, series = {Cytotherapy}, journal = {Cytotherapy}, pages = {1079 -- 1095}, abstract = {BACKGROUND: Cell-based therapies with autologous adipose tissue-derived cells have shown great potential in several clinical studies in the last decades. The majority of these studies have been using the stromal vascular fraction (SVF), a heterogeneous mixture of fibroblasts, lymphocytes, monocytes/macrophages, endothelial cells, endothelial progenitor cells, pericytes and adipose-derived stromal/stem cells (ASC) among others. Although possible clinical applications of autologous adipose tissue-derived cells are manifold, they are limited by insufficient uniformity in cell identity and regenerative potency. METHODS: In our experimental set-up, low-energy extracorporeal shock wave therapy (ESWT) was performed on freshly obtained human adipose tissue and isolated adipose tissue SVF cells aiming to equalize and enhance stem cell properties and functionality. RESULTS: After ESWT on adipose tissue we could achieve higher cellular adenosine triphosphate (ATP) levels compared with ESWT on the isolated SVF as well as the control. ESWT on adipose tissue resulted in a significantly higher expression of single mesenchymal and vascular marker compared with untreated control. Analysis of SVF protein secretome revealed a significant enhancement in insulin-like growth factor (IGF)-1 and placental growth factor (PLGF) after ESWT on adipose tissue. DISCUSSION: Summarizing we could show that ESWT on adipose tissue enhanced the cellular ATP content and modified the expression of single mesenchymal and vascular marker, and thus potentially provides a more regenerative cell population. Because the effectiveness of autologous cell therapy is dependent on the therapeutic potency of the patient's cells, this technology might raise the number of patients eligible for autologous cell transplantation.}, subject = {Shockwave Therapy}, language = {en} } @article{CieślikBoczulaKuepcueRuenzleretal., author = {Cieślik-Boczula, Katarzyna and K{\"u}pc{\"u}, Seta and R{\"u}nzler, Dominik and Koll, Aleksander and K{\"o}hler, Gottfried}, title = {Effects of the phenolic lipid 3-pentadecylphenol on phospholipid bilayer organization}, series = {Journal of Molecular Structure}, journal = {Journal of Molecular Structure}, number = {919(1-3)}, pages = {373 -- 380}, subject = {Phospholipid Bilayer}, language = {en} } @inproceedings{KneblMortonRedletal., author = {Knebl, Gerald and Morton, Tatjana J. and Redl, Heinz and R{\"u}nzler, Dominik}, title = {Mechanical stimulation of cells in 3-dimensional fibrin constructs using a bioreactor}, series = {3. Forschungsforum der {\"o}sterreichischen Fachhochschulen / Fachhochschule K{\"a}rnten}, booktitle = {3. Forschungsforum der {\"o}sterreichischen Fachhochschulen / Fachhochschule K{\"a}rnten}, pages = {492 -- 493}, subject = {Cells}, language = {en} } @article{SchneiderAignerHolnthoneretal., author = {Schneider, Karl Heinrich and Aigner, Petra and Holnthoner, Wolfgang and Monforte Vila, Xavier and N{\"u}rnberger, Sylvia and R{\"u}nzler, Dominik and Redl, Heinz and Teuschl, Andreas}, title = {Decellularized human placenta chorion matrix as a favorable source of small-diameter vascular grafts}, series = {Acta Biomaterialia}, journal = {Acta Biomaterialia}, subject = {Grafting}, language = {en} } @article{RohringerHolnthonerHackletal., author = {Rohringer, Sabrina and Holnthoner, Wolfgang and Hackl, Matthias and Weihs, Anna and R{\"u}nzler, Dominik and Skalicky, Susanna and Karbiener, Michael and Scheideler, Marcel and Pr{\"o}ll, Johannes and Gabriel, Christian and Schweighofer, Bernhard and Gr{\"o}ger, Marion and Spittler, Andreas and Grillari, Johannes and Redl, Heinz}, title = {Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells.}, series = {PLoS one}, journal = {PLoS one}, subject = {Shockwave}, language = {en} } @misc{LiousiaSalzerMandtetal., author = {Liousia, Varvara and Salzer, Elias and Mandt, Denise and R{\"u}nzler, Dominik}, title = {The impact of ethanol in vitro and in vivo: a comparative study}, subject = {In Vivo}, language = {en} } @misc{LiousiaRuenzler, author = {Liousia, Varvara and R{\"u}nzler, Dominik}, title = {Stage- and dose-dependent effects of methanol and ethanol on the locomotor activity of zebrafish larvae}, subject = {Locomotor Activity}, language = {en} }