@inproceedings{SalzbrunnBuschdellaSchiavaetal.,
  author    = {Salzbrunn, Benedikt and Busch, Marc and della Schiava, Marco and Kipke, Christine},
  title     = {rapid UX-score: Modulare und Adaptive Messung von User Experience},
  series = {Mensch und Computer 2020 - Workshopband},
  booktitle = {Mensch und Computer 2020 - Workshopband},
  subject      = {UX Messung},
  language  = {de}
}
@inproceedings{MallyHofstaetterEckelt,
  author    = {Mally, Franziska and Hofst{\"a}tter, Otto and Eckelt, Markus},
  title     = {Influence of Running Shoes and Running Velocity on "Ride" during Running.},
  series = {ISEA 2020 Online - Proceedings 2020},
  booktitle = {ISEA 2020 Online - Proceedings 2020},
  subject      = {Sports Equipment Technologies},
  language  = {en}
}
@article{PurtscherRothbauerKratzetal.,
  author    = {Purtscher, Michaela and Rothbauer, Mario and Kratz, Sebastian Rudi Adam and Bailey, Andrew and Lieberzeit, Peter and Ertl, Peter},
  title     = {A microfluidic impedance-based extended infectivity assay: combining retroviral amplification and cytopathic effect monitoring on a single lab-on-a-chip platform},
  series = {Lab on a Chip},
  volume    = {2021},
  journal   = {Lab on a Chip},
  number    = {Issue 7},
  pages     = {1364 -- 1372},
  abstract  = {Detection, quantification and monitoring of virus - host cell interactions are of great importance when evaluating the safety of pharmaceutical products. With the wide usage of viral based vector systems in combination with mammalian cell lines for the production of biopharmaceuticals, the presence of replication competent viral particles needs to be avoided and potential hazards carefully assessed. Consequently, regulatory agencies recommend viral clearance studies using plaque assays or TCID50 assays to evaluate the efficiency of the production process in removing viruses. While plaque assays provide reliable information on the presence of viral contaminations, they are still tedious to perform and can take up to two weeks to finish. To overcome some of these limitations, we have automated, miniaturized and integrated the dual cell culture bioassay into a common lab-on-a-chip platform containing embedded electrical sensor arrays to enrich and detect infectious viruses. Results of our microfluidic single step assay show that a significant reduction in assay time down to 3 to 4 days can be achieved using simultaneous cell-based viral amplification, release and detection of cytopathic effects in a target cell line. We further demonstrate the enhancing effect of continuous fluid flow on infection of PG-4 reporter cells by newly formed and highly active virions by M. dunni cells, thus pointing to the importance of physical relevant viral-cell interactions.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@article{DeiningerWagnerHeimeletal.,
  author    = {Deininger, Christian and Wagner, Andrea and Heimel, Patrick and Salzer, Elias and Monforte Vila, Xavier and Weißenbacher, Nadja and Grillari, Johannes and Redl, Heinz and Wichlas, Florian and Freude, Thomas and Tempfer, Herbert and Teuschl-Woller, Andreas and Traweger, Andreas},
  title     = {Enhanced BMP-2-Mediated Bone Repair Using an Anisotropic Silk Fibroin Scaffold Coated with Bone-like Apatite},
  series = {Int. J. Mol. Sci.},
  volume    = {23},
  journal   = {Int. J. Mol. Sci.},
  number    = {1 / 283},
  abstract  = {The repair of large bone defects remains challenging and often requires graft material due to limited availability of autologous bone. In clinical settings, collagen sponges loaded with excessive amounts of bone morphogenetic protein 2 (rhBMP-2) are occasionally used for the treatment of bone non-unions, increasing the risk of adverse events. Therefore, strategies to reduce rhBMP-2 dosage are desirable. Silk scaffolds show great promise due to their favorable biocompatibility and their utility for various biofabrication methods. For this study, we generated silk scaffolds with axially aligned pores, which were subsequently treated with 10× simulated body fluid (SBF) to generate an apatitic calcium phosphate coating. Using a rat femoral critical sized defect model (CSD) we evaluated if the resulting scaffold allows the reduction of BMP-2 dosage to promote efficient bone repair by providing appropriate guidance cues. Highly porous, anisotropic silk scaffolds were produced, demonstrating good cytocompatibility in vitro and treatment with 10× SBF resulted in efficient surface coating. In vivo, the coated silk scaffolds loaded with a low dose of rhBMP-2 demonstrated significantly improved bone regeneration when compared to the unmineralized scaffold. Overall, our findings show that this simple and cost-efficient technique yields scaffolds that enhance rhBMP-2 mediated bone healing.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@article{HackethalDungelTeuschl,
  author    = {Hackethal, Johannes and Dungel, Peter and Teuschl, Andreas Herbert},
  title     = {Frequently Used Strategies to Isolate Extracellular Matrix Proteins from Human Placenta and Adipose Tissue},
  series = {Tissue Engineering Part C: Methods},
  volume    = {27},
  journal   = {Tissue Engineering Part C: Methods},
  number    = {12},
  pages     = {649 -- 660},
  abstract  = {The natural extracellular matrix (ECM) provides the optimal environment for cells. Many enzymatic or non-enzymatic based strategies to extract ECM proteins from tissues were published over the past years. However, every single isolation strategy reported so far is associated with specific bottlenecks. In this study, frequently used strategies to isolate ECM from human placenta or adipose tissue using Tris-, serum-, or pepsin-based buffers were compared. The resulting ECM proteins were biochemically characterized by analysis of cellular remnants using Hoechst DNA staining, glycosaminoglycan (GAG) content by dimethylmethylene blue, visualization of protein bands using sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis combined with amino acid quantification, and assessment of the proangiogenic profile using an angiogenesis array. Tris-NaCl-extracted ECM proteins showed a high heterogenic degree of extracted proteins, bioactive growth factors, and GAGs, but no collagen-I. Active serum-extracted ECM showed significant lower DNA remnants when compared with the Tris-NaCl isolation strategy. Pepsin-extracted ECM was rich in collagen-I and low amounts of remaining bioactive growth factors. This strategy was most effective to reduce DNA amounts when compared with the other isolation strategies. Pepsin-extracted ECM from both tissues easily gelled at 37°C, whereas the other extracted ECM strategies did not gel at 37°C (Tris-NaCl: liquid; serum: sponge). All relevant characteristics (DNA residues, ECM diversity and bioactivity, shape) of the extracted ECM proteins highly depend on its isolation strategy and could still be optimized. Impact statement The natural human extracellular matrix (ECM) is the ideal cell niche. Various strategies were reported to isolate human ECM components from various sources. In this article, we compared frequently used methods and compared their characteristics (DNA remnants, glycosaminoglycan content, sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis, amino acid quantification, angiogenesis array, and gel formation). We conclude that more research is still necessary to optimize current isolation approaches for in vitro or in vivo applications of human ECM.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@article{KhimichProsolovMishurovaetal.,
  author    = {Khimich, Margarita A. and Prosolov, Konstantin A. and Mishurova, Tatiana and Evsevleev, Sergej and Monforte, Xavier and Teuschl, Andreas H. and Slezak, Paul and Ibragimov, Egor A. and Saprykin, Alexander A. and Kovalevskaya, Zhanna G. and Dmitriev, Andrey I. and Bruno, Giovanni and Sharkeev, Yurii P.},
  title     = {Advances in Laser Additive Manufacturing of Ti-Nb Alloys: From Nanostructured Powders to Bulk Objects},
  series = {Nanomaterials (Basel)},
  volume    = {11},
  journal   = {Nanomaterials (Basel)},
  number    = {5 / 1159},
  abstract  = {The additive manufacturing of low elastic modulus alloys that have a certain level of porosity for biomedical needs is a growing area of research. Here, we show the results of manufacturing of porous and dense samples by a laser powder bed fusion (LPBF) of Ti-Nb alloy, using two distinctive fusion strategies. The nanostructured Ti-Nb alloy powders were produced by mechanical alloying and have a nanostructured state with nanosized grains up to 90 nm. The manufactured porous samples have pronounced open porosity and advanced roughness, contrary to dense samples with a relatively smooth surface profile. The structure of both types of samples after LPBF is formed by uniaxial grains having micro- and nanosized features. The inner structure of the porous samples is comprised of an open interconnected system of pores. The volume fraction of isolated porosity is 2 vol. \% and the total porosity is 20 vol. \%. Cell viability was assessed in vitro for 3 and 7 days using the MG63 cell line. With longer culture periods, cells showed an increased cell density over the entire surface of a porous Ti-Nb sample. Both types of samples are not cytotoxic and could be used for further in vivo studies.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@article{FarokhiAleemardaniSolouketal.,
  author    = {Farokhi, Maryam and Aleemardani, Mina and Solouk, Atefeh and Mirzadeh, Hamid and Teuschl, Andreas Herbert and Redl, Heinz},
  title     = {Crosslinking strategies for silk fibroin hydrogels: promising biomedical materials},
  series = {Biomedical Materials},
  volume    = {16},
  journal   = {Biomedical Materials},
  number    = {2},
  pages     = {022004},
  abstract  = {Due to their strong biomimetic potential, silk fibroin (SF) hydrogels are impressive candidates for tissue engineering, due to their tunable mechanical properties, biocompatibility, low immunotoxicity, controllable biodegradability, and a remarkable capacity for biomaterial modification and the realization of a specific molecular structure. The fundamental chemical and physical structure of SF allows its structure to be altered using various crosslinking strategies. The established crosslinking methods enable the formation of three-dimensional (3D) networks under physiological conditions. There are different chemical and physical crosslinking mechanisms available for the generation of SF hydrogels (SFHs). These methods, either chemical or physical, change the structure of SF and improve its mechanical stability, although each method has its advantages and disadvantages. While chemical crosslinking agents guarantee the mechanical strength of SFH through the generation of covalent bonds, they could cause some toxicity, and their usage is not compatible with a cell-friendly technology. On the other hand, physical crosslinking approaches have been implemented in the absence of chemical solvents by the induction of β-sheet conformation in the SF structure. Unfortunately, it is not easy to control the shape and properties of SFHs when using this method. The current review discusses the different crosslinking mechanisms of SFH in detail, in order to support the development of engineered SFHs for biomedical applications.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@inproceedings{Mally,
  author    = {Mally, Franziska},
  title     = {In-Shoe Plantar Pressure Measurement—Influence of Insole Placement on Selected Parameters during Running.},
  series = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  booktitle = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  pages     = {50 -- 50},
  subject      = {Sports Equipment Technologies},
  language  = {en}
}
@article{ZiadlouRotmanTeuschletal.,
  author    = {Ziadlou, Reihane and Rotman, Stijn and Teuschl, Andreas and Salzer, Elias and Barbero, Andrea and Martin, Ivan and Alini, Mauro and Eglin, David and Grad, Sibylle},
  title     = {Optimization of hyaluronic acid-tyramine/silk-fibroin composite hydrogels for cartilage tissue engineering and delivery of anti-inflammatory and anabolic drugs},
  series = {Materials Science and Engineering: C},
  volume    = {120},
  journal   = {Materials Science and Engineering: C},
  number    = {111701},
  abstract  = {Injury of articular cartilage leads to an imbalance in tissue homeostasis, and due to the poor self-healing capacity of cartilage the affected tissue often exhibits osteoarthritic changes. In recent years, injectable and highly tunable composite hydrogels for cartilage tissue engineering and drug delivery have been introduced as a desirable alternative to invasive treatments. In this study, we aimed to formulate injectable hydrogels for drug delivery and cartilage tissue engineering by combining different concentrations of hyaluronic acid-tyramine (HA-Tyr) with regenerated silk-fibroin (SF) solutions. Upon enzymatic crosslinking, the gelation and mechanical properties were characterized over time. To evaluate the effect of the hydrogel compositions and properties on extracellular matrix (ECM) deposition, bovine chondrocytes were embedded in enzymatically crosslinked HA-Tyr/SF composites (in further work abbreviated as HA/SF) or HA-Tyr hydrogels. We demonstrated that all hydrogel formulations were cytocompatible and could promote the expression of cartilage matrix proteins allowing chondrocytes to produce ECM, while the most prominent chondrogenic effects were observed in hydrogels with HA20/SF80 polymeric ratios. Unconfined mechanical testing showed that the compressive modulus for HA20/SF80 chondrocyte-laden constructs was increased almost 10-fold over 28 days of culture in chondrogenic medium which confirmed the superior production of ECM in this hydrogel compared to other hydrogels in this study. Furthermore, in hydrogels loaded with anabolic and anti-inflammatory drugs, HA20/SF80 hydrogel showed the longest and the most sustained release profile over time which is desirable for the long treatment duration typically necessary for osteoarthritic joints. In conclusion, HA20/SF80 hydrogel was successfully established as a suitable injectable biomaterial for cartilage tissue engineering and drug delivery applications.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@article{FrohnerMenseKrondrafetal.,
  author    = {Frohner, Matthias and Mense, Alexander and Krondraf, Nikolaus and Sabutsch, Stefan},
  title     = {Implementierungsleitfaden HL7 Implementation Guide for CDA® R2: Implementierungsleitfaden Meldung an das Epidemiologische Meldesystem (EMS) - Labor-und Arztmeldung, ELGA GmbH},
  series = {ELGA CDA Implementierungsleitf{\"a}den HL7},
  volume    = {2020},
  journal   = {ELGA CDA Implementierungsleitf{\"a}den HL7},
  subject      = {eHealth},
  language  = {de}
}
@article{FrohnerSabutschKrondraf,
  author    = {Frohner, Matthias and Sabutsch, Stefan and Krondraf, Nikolaus},
  title     = {ELGA CDA Implementierungsleitf{\"a}den HL7 Implementation Guide for CDA® R2: Ambulanzbefund, ELGA GmbH},
  series = {ELGA CDA Implementierungsleitf{\"a}den HL7},
  volume    = {2020},
  journal   = {ELGA CDA Implementierungsleitf{\"a}den HL7},
  subject      = {eHealth},
  language  = {de}
}
@inproceedings{EckeltMally,
  author    = {Eckelt, Markus and Mally, Franziska},
  title     = {Running Shoes—Possible Correlations of Biomechanical and Material Tests.},
  series = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  booktitle = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  pages     = {25 -- 25},
  subject      = {Sports Equipment Technologies},
  language  = {en}
}
@inproceedings{EckeltMally,
  author    = {Eckelt, Markus and Mally, Franziska},
  title     = {Use of Acceleration Sensors in Archery},
  series = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  booktitle = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  pages     = {98 -- 98},
  subject      = {Sports Equipment Technologies},
  language  = {en}
}
@article{JesenbergerZmajkovicovaCatalanottietal.,
  author    = {Jesenberger, Veronika and Zmajkovicova, Katarina and Catalanotti, Federica and Baumgartner, Christian and Reyes, Gloria Ximena and Baccarini, Manuela},
  title     = {MEK1 is required for PTEN membrane recruitment, AKT regulation, and the maintenance of peripheral tolerance},
  series = {Mol. Cell},
  volume    = {2013},
  journal   = {Mol. Cell},
  number    = {50},
  pages     = {43 -- 55},
  abstract  = {The Raf/MEK/ERK and PI3K/Akt pathways are prominent effectors of oncogenic Ras. These pathways negatively regulate each other, but the mechanism involved is incompletely understood. We now identify MEK1 as an essential regulator of lipid/protein phosphatase PTEN, through which it controls phosphatidylinositol-3-phosphate accumulation and AKT signaling. MEK1 ablation stabilizes AKT activation and, in vivo, causes a lupus-like autoimmune disease and myeloproliferation. Mechanistically, MEK1 is necessary for PTEN membrane recruitment as part of a ternary complex containing the multidomain adaptor MAGI1. Complex formation is independent of MEK1 kinase activity but requires phosphorylation of T292 on MEK1 by activated ERK. Thus, inhibiting the ERK pathway reduces PTEN membrane recruitment, increasing phosphatidylinositol-3-phosphate accumulation and AKT activation. Our data offer a conceptual framework for the observation that activation of the PI3K pathway frequently mediate resistance to MEK inhibitors and for the promising results obtained by combined MEK/PI3K inhibition in preclinical cancer models.},
  subject      = {MEK1 pathway},
  language  = {en}
}
@article{CatalanottiReyesJesenbergeretal.,
  author    = {Catalanotti, Federica and Reyes, Gloria Ximena and Jesenberger, Veronika and Galabova-Kovacs, Gergana and de Matos Simoes, Ricardo and Carugo, Oliviero and Baccarini, Manuela},
  title     = {A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal},
  series = {Nat Struct Mol Biol.},
  volume    = {2009},
  journal   = {Nat Struct Mol Biol.},
  number    = {16(3)},
  pages     = {294 -- 303},
  abstract  = {Mek1 and Mek2 (also known as Map2k1 and Map2k2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion and growth factor signaling. Here we describe a previously uncharacterized, unexpected role of Mek1 in downregulating Mek2-dependent Erk signaling. Mek1 mediates the regulation of Mek2 in the context of a previously undiscovered Mek1-Mek2 complex. The Mek heterodimer is negatively regulated by Erk-mediated phosphorylation of Mek1 on Thr292, a residue missing in Mek2. Disabling this Erk-proximal negative-feedback step stabilizes the phosphorylation of both Mek2 and Erk in cultured cells and in vivo in Mek1 knockout embryos and mice. Thus, in disagreement with the current perception of the pathway, the role of Mek1 and Mek2 in growth factor-induced Erk phosphorylation is not interchangeable. Our data establish Mek1 as the crucial modulator of Mek and Erk signaling and have potential implications for the role of Mek1 and Mek2 in tumorigenesis.},
  subject      = {Mek1-Mek2 pathway},
  language  = {en}
}
@inproceedings{PeschaHorauer,
  author    = {Pescha, David and Horauer, Martin},
  title     = {Eventroms in IEC 61499 Applications},
  series = {Proceedings of XXXIII Conference on Design of Circuits and Integrated Systems (DCIS '2018), November 14-16, 2018, Lyon, France},
  booktitle = {Proceedings of XXXIII Conference on Design of Circuits and Integrated Systems (DCIS '2018), November 14-16, 2018, Lyon, France},
  isbn      = {978-1-7281-0171-2},
  pages     = {6},
  subject      = {IEC Standards},
  language  = {en}
}
@inproceedings{Dolezal,
  author    = {Dolezal, Dominik},
  title     = {Educational Design Patterns for Student-Centered 21st Century Learning in Technology-Enhanced Learning Environments},
  series = {Educating Engineers for Future Industrial Revolutions: Proceedings of the 23rd International Conference on Interactive Collaborative Learning (ICL2020)},
  booktitle = {Educating Engineers for Future Industrial Revolutions: Proceedings of the 23rd International Conference on Interactive Collaborative Learning (ICL2020)},
  subject      = {21st century skills},
  language  = {en}
}
@inproceedings{Dolezal,
  author    = {Dolezal, Dominik},
  title     = {The Learning Office Approach to Modern 21st Century Education: Third Evaluation of a Self-Driven Concept for Student-Centered Engineering Education},
  series = {IEEE 50th Annual Frontiers in Education Conference},
  booktitle = {IEEE 50th Annual Frontiers in Education Conference},
  subject      = {learning office},
  language  = {en}
}
@article{KrautwaldBuescherJesenbergeretal.,
  author    = {Krautwald, Stefan and B{\"u}scher, Dirk and Jesenberger, Veronika and Buder, Sylke and Baccarini, Manuela},
  title     = {Involvement of the protein tyrosine phosphatase SHP-1 in Ras-mediated activation of the mitogen-activated protein kinase pathway.},
  series = {Mol Cell Biol.},
  volume    = {1996},
  journal   = {Mol Cell Biol.},
  number    = {16(11)},
  doi       = {doi: 10.1128/mcb.16.11.5955},
  pages     = {5955 -- 5963},
  abstract  = {Ubiquitously expressed SH2-containing tyrosine phosphatases interact physically with tyrosine kinase receptors or their substrates and relay positive mitogenic signals via the activation of the Ras-mitogen-activated protein kinase (MAPK) pathway. Conversely, the structurally related phosphatase SHP-1 is predominantly expressed in hemopoietic cells and becomes tyrosine phosphorylated upon colony-stimulating factor 1 treatment of macrophages without associating with the colony-stimulating factor 1 receptor tyrosine kinase. Mice lacking functional SHP-1 (me/me and me(v)/me(v)) develop systemic autoimmune disease with accumulation of macrophages, suggesting that SHP-1 may be a negative regulator of hemopoietic cell growth. By using macrophages expressing dominant negative Ras and the me(v)/me(v) mouse mutant, we show that SHP-1 is activated in the course of mitogenic signal transduction in a Ras-dependent manner and that its activity is necessary for the Ras-dependent activation of the MAPK pathway but not of the Raf-1 kinase. Consistent with a role for SHP-1 as an intermediate between Ras and the MEK-MAPK pathway, Ras-independent activation of the latter kinases by bacterial lipopolysaccharide occurred normally in me(v)/me(v) cells. Our results sharply accentuate the diversity of signal transduction in mammalian cells, in which the same signaling intermediates can be rearranged to form different pathways.},
  subject      = {Molecular Cell Biology},
  language  = {en}
}
@article{JesenbergerProcykYuanetal.,
  author    = {Jesenberger, Veronika and Procyk, Katarzyna and Yuan, Junying and Reipert, Siegfried and Baccarini, Manuela},
  title     = {Salmonella-induced caspase-2 activation in macrophages: a novel mechanism in pathogen-mediated apoptosis},
  series = {J Exp Med.},
  volume    = {2000},
  journal   = {J Exp Med.},
  number    = {192(7)},
  doi       = {10.1084/jem.192.7.1035},
  pages     = {1035 -- 1046},
  abstract  = {The enterobacterial pathogen Salmonella induces phagocyte apoptosis in vitro and in vivo. These bacteria use a specialized type III secretion system to export a virulence factor, SipB, which directly activates the host's apoptotic machinery by targeting caspase-1. Caspase-1 is not involved in most apoptotic processes but plays a major role in cytokine maturation. We show that caspase-1-deficient macrophages undergo apoptosis within 4-6 h of infection with invasive bacteria. This process requires SipB, implying that this protein can initiate the apoptotic machinery by regulating components distinct from caspase-1. Invasive Salmonella typhimurium targets caspase-2 simultaneously with, but independently of, caspase-1. Besides caspase-2, the caspase-1-independent pathway involves the activation of caspase-3, -6, and -8 and the release of cytochrome c from mitochondria, none of which occurs during caspase-1-dependent apoptosis. By using caspase-2 knockout macrophages and chemical inhibition, we establish a role for caspase-2 in both caspase-1-dependent and -independent apoptosis. Particularly, activation of caspase-1 during fast Salmonella-induced apoptosis partially relies on caspase-2. The ability of Salmonella to induce caspase-1-independent macrophage apoptosis may play a role in situations in which activation of this protease is either prevented or uncoupled from the induction of apoptosis.},
  subject      = {caspase-2 activation in macrophages},
  language  = {en}
}
@article{JesenbergerProcykRuethetal.,
  author    = {Jesenberger, Veronika and Procyk, Katarzyna and R{\"u}th, Jochen and Schreiber, Martin and Theussl, Hans Christian and Wagner, Erwin and Baccarini, Manuela},
  title     = {Protective Role of Raf-1 in Salmonella-Induced Macrophage Apoptosis},
  series = {J Exp Med.},
  volume    = {2001},
  journal   = {J Exp Med.},
  number    = {193(3)},
  doi       = {10.1084/jem.193.3.353},
  pages     = {353 -- 364},
  abstract  = {Invasive Salmonella induces macrophage apoptosis via the activation of caspase-1 by the bacterial protein SipB. Here we show that infection of macrophages with Salmonella causes the activation and degradation of Raf-1, an important intermediate in macrophage proliferation and activation. Raf-1 degradation is SipB- and caspase-1-dependent, and is prevented by proteasome inhibitors. To study the functional significance of Raf-1 in this process, the c-raf-1 gene was inactivated by Cre-loxP-mediated recombination in vivo. Macrophages lacking c-raf-1 are hypersensitive towards pathogen-induced apoptosis. Surprisingly, activation of the antiapoptotic mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) and nuclear factor κB pathways is normal in Raf-1-deficient macrophages, and mitochondrial fragility is not increased. Instead, pathogen-mediated activation of caspase-1 is enhanced selectively, implying that Raf-1 antagonizes stimulus-induced caspase-1 activation and apoptosis.},
  subject      = {Salmonella-Induced Macrophage Apoptosis},
  language  = {en}
}
@article{JesenbergerJentsch,
  author    = {Jesenberger, Veronika and Jentsch, Stefan},
  title     = {Deadly encounter: ubiquitin meets apoptosis},
  series = {Nat Rev Mol Cell Biol.},
  volume    = {2002},
  journal   = {Nat Rev Mol Cell Biol.},
  number    = {3(2)},
  doi       = {https://doi.org/10.1038/nrm731},
  pages     = {112 -- 121},
  abstract  = {The ubiquitin/proteasome pathway is the main non-lysosomal route for intracellular protein degradation in eukaryotes. It is instrumental to various cellular processes, such as cell-cycle progression, transcription and antigen processing. Recent findings also substantiate a pivotal role of the ubiquitin/proteasome pathway in the regulation of apoptosis. Regulatory molecules that are involved in programmed cell death have been identified as substrates of the proteasome. Moreover, key regulators of apoptosis themselves seem to have an active part in the proteolytic inactivation of death executors.},
  subject      = {programmed cell death},
  language  = {en}
}
@inproceedings{Litzenberger,
  author    = {Litzenberger, Stefan},
  title     = {A Study of Skin-Close Heat and Moisture with Different Types of Backpacks in Cycling.},
  series = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  booktitle = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  pages     = {86 -- 86},
  subject      = {Sports Equipment Technologies},
  language  = {en}
}
@misc{Rohatsch,
  author    = {Rohatsch, Lukas},
  title     = {Open Data Workshop},
  subject      = {Open Data},
  language  = {de}
}
@article{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {Preservation of Individuals' Privacy in Shared COVID-19 Related Data},
  series = {COVID-19 Data sharing in epidemiology, version 0.054.},
  journal   = {COVID-19 Data sharing in epidemiology, version 0.054.},
  editor    = {RDA-COVID19-Epidemiology WG., Research Data Alliance},
  pages     = {13},
  abstract  = {This paper provides insight into how restricted data can be incorporated in an open-be-default-by-design digital infrastructure for scientific data. We focus, in particular, on the ethical component of FAIRER (Findable, Accessible, Interoperable, Ethical, and Reproducible) data, and the pseudo-anonymization and anonymization of COVID-19 datasets to protect personally identifiable information (PII). First we consider the need for the customisation of the existing privacy preservation techniques in the context of rapid production, integration, sharing and analysis of COVID-19 data. Second, the methods for the pseudo-anonymization of direct identification variables are discussed. We also discuss different pseudo-IDs of the same person for multi-domain and multi-organization. Essentially, pseudo-anonymization and its encrypted domain specific IDs are used to successfully match data later, if required and permitted, as well as to restore the true ID (and authenticity) in individual cases of a patient's clarification.Third, we discuss application of statistical disclosure control (SDC) techniques to COVID-19 disease data. To assess and limit the risk of re-identification of individual persons in COVID-19 datasets (that are often enriched with other covariates like age, gender, nationality, etc.) to acceptable levels, the risk of successful re-identification by a combination of attribute values must be assessed and controlled. This is done using statistical disclosure control for anonymization of data. Lastly, we discuss the limitations of the proposed techniques and provide general guidelines on using disclosure risks to decide on appropriate modes for data sharing to preserve the privacy of the individuals in the datasets.},
  subject      = {COVID19},
  language  = {en}
}
@inproceedings{Orsolits,
  author    = {Orsolits, Horst},
  title     = {Virtual Engineering Applied in a Digital Learning Factory},
  series = {Perspectives in Industry Digitalization and Advanced Manufacturing in the Black Sea Region},
  booktitle = {Perspectives in Industry Digitalization and Advanced Manufacturing in the Black Sea Region},
  subject      = {Virtual Engineering},
  language  = {de}
}
@inproceedings{Litzenberger,
  author    = {Litzenberger, Stefan},
  title     = {The Influence of Backpack-Design on Thermophysiological Parameters during Simulated Hiking Activities.},
  series = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  booktitle = {ISEA 2020 Online - Proceedings 2020, 49(1)},
  pages     = {59 -- 59},
  subject      = {Sports Equipment Technologies},
  language  = {en}
}
@article{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {COVID-19 Questionnaires, Surveys, and Item-Banks: Overview of Clinical- and Population-Based Instruments},
  series = {SSRN},
  journal   = {SSRN},
  abstract  = {New COVID-19 related instruments are being rapidly developed around the world to collect patient- and population-based information. Heterogeneity between instruments limits comparability of results. The present study provides an overview of instruments and resources. We scoped the content domain on a selection of instruments using the Maelstrom taxonomy. Content of the instruments varied widely, from proximal measures (e.g., clinical symptoms, comorbidities, etc.) to distal measures such as political attitudes. We recommend that researchers reuse existing instruments to the greatest extent possible, and that they make results openly available in machine-readable format to facilitate reuse and maximize comparability of results across studies and countries.},
  subject      = {COVID19},
  language  = {en}
}
@misc{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {FSR Online Debate: Facilitating interoperability of energy services in Europe - (what) can we learn from existing experience?"},
  subject      = {Interoperability},
  language  = {en}
}
@misc{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {Die Gazelle in der Krankenhaus-IT - neue Wege f{\"u}r die Sicherheitstechnische Kontrolle und Leistungs{\"u}berpr{\"u}fung},
  subject      = {Krankenhaus IT},
  language  = {de}
}
@misc{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {Presentation of successful use of IHE profiles in national strategies (Austria and Switzerland)},
  organization    = {EU; Czech Ministry of Health},
  subject      = {eHealth},
  language  = {en}
}
@misc{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {Interoperabilit{\"a}t von Prozessen und IT-Systemen im Gesundheitswesen},
  organization    = {{\"O}sterreichische Gesellschaft f{\"u}r Gute Analysen und Laborpraxis},
  subject      = {QM und Digitalisierung},
  language  = {de}
}
@misc{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {Forum Spital f{\"u}r Manager 2019 - Digitalisierung im Krankenhaus - Vorsitzender},
  organization    = {imh Konferenzen und Seminare},
  subject      = {eHealth},
  language  = {de}
}
@misc{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {Data and Integrated Health Care: � Potential and Challenges of IT innovation},
  subject      = {eHealth},
  language  = {en}
}
@misc{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {The potential of multi-stakeholder alignment in diabetes},
  subject      = {Diabetes},
  language  = {en}
}
@misc{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {IHE Education \& IHE Internationales},
  subject      = {Health Interoperability},
  language  = {en}
}
@inproceedings{Waller,
  author    = {Waller, Daniela},
  title     = {Did COVID19 improve our teaching?},
  series = {ICERI - 13th annual International Conference of Education, Research and Innovation},
  booktitle = {ICERI - 13th annual International Conference of Education, Research and Innovation},
  subject      = {Covid19},
  language  = {en}
}
@misc{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {Software -eine Aufgabe f{\"u}r den TSB?Orientierung im Dschungel der Beauftragten!},
  subject      = {eHealth},
  language  = {de}
}
@misc{Rohatsch,
  author    = {Rohatsch, Lukas},
  title     = {Open Data Projects},
  subject      = {Open Data},
  language  = {en}
}
@article{Sauermann,
  author    = {Sauermann, Stefan},
  title     = {RDA COVID-19 Working Group. Recommendations and Guidelines on data sharing},
  series = {Research Data Alliance, 2020.},
  journal   = {Research Data Alliance, 2020.},
  abstract  = {The Research Data Alliance (RDA) COVID-19 Working Group members bring various, global expertise to develop a body of work that comprises how data from multiple disciplines inform response to a pandemic combined with guidelines and recommendations on data sharing under the present COVID-19 cicumstances. This extends to research software sharing, in recognition of the key role in software in analysing data. The work has been divided into four research areas (namely, clinical, omics, epidemiology, social sciences) with four cross cutting themes (namely, community participation, indigenous data, legal and ethical considerations, research software), as a way to focus the conversations, and provide an initial set of guidelines in a tight timeframe. The detailed guidelines are aimed to help stakeholders follow best practices to maximise the efficiency of their work, and to act as a blueprint for future emergencies. The recommendations in the document are aimed at helping policymakers and funders to maximise timely, quality data sharing and appropriate responses in such health emergencies. This work was executed in an intense period over just over 6 weeks, with five iterations, all of which were opened for public community comment. Draft releases and comments are avaialable here (https://doi.org/10.15497/rda00046). This activity has been conducted under the RDA guiding principles of Openness, Consensus, Balance, Harmonization, Community-driven, and Non-profit and technology-neutral.},
  subject      = {COVID19 Data Sharing},
  language  = {en}
}
@book{OrsolitsLackner,
  author    = {Orsolits, Horst and Lackner, Maximilian},
  title     = {Virtual Reality und Augmented Reality in der Digitalen Produktion},
  publisher = {Gabler},
  isbn      = {978-3-658-29008-5},
  publisher      = {Fachhochschule Technikum Wien},
  subject      = {Virtual Reality},
  language  = {de}
}
@techreport{Pasteka,
  author    = {Pasteka, Richard},
  title     = {Der Standard, "Eine Lunge, die Beatmungsger{\"a}te testet", 2019, Vienna, Austria.},
  subject      = {Lungensimulation},
  language  = {de}
}
@book{PastekaHruškovaJakubiketal.,
  author    = {Pasteka, Richard and Hruškov{\´a}, Jana and Jakub{\´i}k, Juraj and Hendrych, Michal and Svačinov{\´a}, Jana and Nov{\´a}kov{\´a}, Zuzana and Vejtasov{\´a}, Veronika and Kujalov{\´a}, Veronika and Budinskaya, Ksenia},
  title     = {Fyziologie - teorie k praktick{\´y}m cvičen{\´i}m},
  publisher = {Masarykova univerzita, Fakulta informatiky Masarykovy univerzity},
  address   = {Brno},
  publisher      = {Fachhochschule Technikum Wien},
  subject      = {Physiology},
  language  = {mul}
}
@misc{Pasteka,
  author    = {Pasteka, Richard},
  title     = {International Lecture, University of Tr{\´a}s-os-Montes and Alto Douro, Portugal, "Human Respiratory System Modelling"},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@book{HruškovaPastekaJakubiketal.,
  author    = {Hruškov{\´a}, Jana and Pasteka, Richard and Jakub{\´i}k, Juraj and Hendrych, Michal and Svačinov{\´a}, Jana and Nov{\´a}kov{\´a}, Zuzana and Vejtasov{\´a}, Veronika and Kujalov{\´a}, Veronika and Budinskaya, Ksenia},
  title     = {Workbook fyziologie protokoly},
  publisher = {Masarykova univerzita},
  address   = {Brno},
  isbn      = {978-80-210-9897-8},
  publisher      = {Fachhochschule Technikum Wien},
  subject      = {Physiology},
  language  = {mul}
}
@inproceedings{PastekaForjan,
  author    = {Pasteka, Richard and Forjan, Mathias},
  title     = {Actively breathing mechanical lung simulator development and preliminary measurements},
  series = {IFMBE,volume 65; EMBEC \& NBC 2017},
  booktitle = {IFMBE,volume 65; EMBEC \& NBC 2017},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@article{PastekaForjanSauermannetal.,
  author    = {Pasteka, Richard and Forjan, Mathias and Sauermann, Stefan and Drauschke, Andreas},
  title     = {Electro-mechanical Lung Simulator Using Polymer and Organic Human Lung Equivalents for Realistic Breathing Simulation},
  series = {Scientific Reports},
  volume    = {Vol 9},
  journal   = {Scientific Reports},
  number    = {No. 1},
  pages     = {Article number: 19778},
  abstract  = {Simulation models in respiratory research are increasingly used for medical product development and testing, especially because in-vivo models are coupled with a high degree of complexity and ethical concerns. This work introduces a respiratory simulation system, which is bridging the gap between the complex, real anatomical environment and the safe, cost-effective simulation methods. The presented electro-mechanical lung simulator, xPULM, combines in-silico, ex-vivo and mechanical respiratory approaches by realistically replicating an actively breathing human lung. The reproducibility of sinusoidal breathing simulations with xPULM was verified for selected breathing frequencies (10-18 bpm) and tidal volumes (400-600 ml) physiologically occurring during human breathing at rest. Human lung anatomy was modelled using latex bags and primed porcine lungs. High reproducibility of flow and pressure characteristics was shown by evaluating breathing cycles (nTotal = 3273) with highest standard deviation |3σ| for both, simplified lung equivalents (μV˙ = 23.98 ± 1.04 l/min, μP = -0.78 ± 0.63 hPa) and primed porcine lungs (μV˙ = 18.87 ± 2.49 l/min, μP = -21.13 ± 1.47 hPa). The adaptability of the breathing simulation parameters, coupled with the use of porcine lungs salvaged from a slaughterhouse process, represents an advancement towards anatomically and physiologically realistic modelling of human respiration.},
  subject      = {Breathing Simulation},
  language  = {en}
}
@misc{Pasteka,
  author    = {Pasteka, Richard},
  title     = {International Week Turku, "Hands-on learning and research applications"},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@inproceedings{PastekaSantosdaCostaForjan,
  author    = {Pasteka, Richard and Santos da Costa, Joao Pedro and Forjan, Mathias},
  title     = {Characteristic Waveforms for Testing of Medical Aerosol Inhalers},
  series = {8th European Medical and Biological Engineering Conference},
  booktitle = {8th European Medical and Biological Engineering Conference},
  publisher = {Springer International Publishing},
  pages     = {240 -- 246},
  abstract  = {Respiratory diseases are characterised by high prevalence among the European population. Medical aerosol inhalers are the most commonly used means of drug delivery into the human respiratory system. This paper focuses on characteristic waveforms that can be utilised during aerosol deposition studies to simulate conditions of rapid human inhalation. Additionally, an inhalatory waveform based on clinically recorded spirometry data is introduced. Experimental measurements are performed and simulation results mutually compared using the electro-mechanical lung simulator xPULM. The inhalatory waveforms are repeatably simulated with high fidelity in regards to the waveform shape with the lowest value of the Goodness of fit 0.89. Additionally, the measured values for all characteristic inhalatory parameters are simulated with low standard deviation < 1. The differences between the required and measured waveform shapes are small, < 3 L/min and do not influence the overall inhalatory volume. This opens a possibility of utilising the xPULM for medical aerosol inhalers testing.},
  subject      = {Breathing Simulation},
  language  = {en}
}
@inproceedings{PastekaForjan,
  author    = {Pasteka, Richard and Forjan, Mathias},
  title     = {Changes of particle deposition caused by different breathing patterns during active lung simulation},
  series = {41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)},
  booktitle = {41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)},
  abstract  = {Aerosols are an integral part of everyday life and as such are inhaled under various conditions and circumstances. These may vary based on the health and activity status of an individual. The aim of this work is to analyse the particle deposition mechanisms during the simulation of three different breathing patterns using an aerosol representing the PM1 fraction of fine particles. The active electro-mechanical lung simulator xPULM is utilized as a driving force and is combined with a non-invasive direct reading optical aerosol measurement system. Results show differences between the number of deposited particles for the three breathing patterns and for the three typical size ranges of airborne particles. Overall, the presented approach demonstrates the possibility of determining the changes of aerosol uptake based on different breathing patterns using the electro-mechanical lung simulator and laboratory produced aerosols. Further measurement cycles must be performed in order to validate the found interactions and to characterize the major influencing parameters.},
  subject      = {Biomedical Engineering, Breathing simulation},
  language  = {en}
}
@misc{PastekaForjanDrauschke,
  author    = {Pasteka, Richard and Forjan, Mathias and Drauschke, Andreas},
  title     = {Comparison of breathing patterns for aerosol inhalation using an electro-mechanical lung simulator},
  series = {ALTEX Proceedings - EUSAAT 2018, Linz},
  journal   = {ALTEX Proceedings - EUSAAT 2018, Linz},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@misc{ForjanPastekaDrauschke,
  author    = {Forjan, Mathias and Pasteka, Richard and Drauschke, Andreas},
  title     = {Lung simulation - an alterna� tive approach to animal testing for applications in aerosol and respiratory research},
  series = {ALTEX Proceedings - EUSAAT 2018, Linz},
  journal   = {ALTEX Proceedings - EUSAAT 2018, Linz},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@inproceedings{PastekaForjanSauermann,
  author    = {Pasteka, Richard and Forjan, Mathias and Sauermann, Stefan},
  title     = {Development of a multidisciplinary and telemedicine focused system database},
  series = {Health Informatics meets eHealth. Digital Insight - Information-Driven Health \& Care Proceedings of the 11th eHealth2017 Conference (Studies in Health Technology and Informatics, Volume 236)},
  booktitle = {Health Informatics meets eHealth. Digital Insight - Information-Driven Health \& Care Proceedings of the 11th eHealth2017 Conference (Studies in Health Technology and Informatics, Volume 236)},
  publisher = {IOS Press eBooks},
  pages     = {144 -- 151},
  abstract  = {Tele-rehabilitation at home is one of the promising approaches in increasing rehabilitative success and simultaneously decreasing the financial burden on the healthcare system. Objectives: Novel and mostly mobile devices are already in use, but shall be used in the future to a higher extent for allowing at home rehabilitation processes at a high quality level. The combination of exercises, assessments and available equipment is the basic objective of the presented database. Methods: The database has been structured in order to allow easy-to-use and fast access for the three main user groups. Therapists - looking for exercise and equipment combinations - patients - rechecking their tasks for home exercises - and manufacturers - entering their equipment for specific use cases. Results: The database has been evaluated by a proof of concept study and shows a high degree of applicability for the field of rehabilitative medicine. Currently it contains 110 exercises/assessments and 111 equipment/systems. Conclusion: Foundations of presented database are already established in the rehabilitative field of application, but can and will be enhanced in its functionality to be usable for a higher variety of medical fields and specificatios.},
  subject      = {telemedicine},
  language  = {en}
}
@misc{Pasteka,
  author    = {Pasteka, Richard},
  title     = {Applications of Biomedical Engineering in Respiratory Care},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@inproceedings{PastekaForjan,
  author    = {Pasteka, Richard and Forjan, Mathias},
  title     = {Changes of particle deposition caused by different breathing patterns during active lung simulation},
  series = {41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019},
  booktitle = {41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019},
  organization    = {IEEE},
  pages     = {4969 -- 4972},
  subject      = {Lung Simulation},
  language  = {en}
}
@inproceedings{HimmelstossIzVotzi,
  author    = {Himmelstoß, Felix and Iz, Ali and Votzi, Helmut},
  title     = {Quadratic bidirectional buck-boost converter},
  series = {Proceedings of 2020 International Symposium on Power Electronics, Electrical Drives, Automation and Motion (SPEEDAM), Sorrento, Italy, June 24-26, 2020},
  booktitle = {Proceedings of 2020 International Symposium on Power Electronics, Electrical Drives, Automation and Motion (SPEEDAM), Sorrento, Italy, June 24-26, 2020},
  pages     = {738 -- 743},
  subject      = {Buck-Boost converter},
  language  = {en}
}
@article{HimmelstossVotzi,
  author    = {Himmelstoß, Felix and Votzi, Helmut},
  title     = {Feedforward Control of Quadratic Converters},
  series = {WSEAS Transactions of Circuits and Systems},
  volume    = {20},
  journal   = {WSEAS Transactions of Circuits and Systems},
  number    = {2021},
  pages     = {147 -- 155},
  subject      = {DC/DC converters},
  language  = {en}
}
@inproceedings{HimmelstossVotzi,
  author    = {Himmelstoß, Felix and Votzi, Helmut},
  title     = {Four quadratic DC/DC converters with one low-side switch and a tapped inductor at the input side},
  series = {Proceedings of IECON 2019, 45th Annual Conference of the IEEE Industrial Electronics Society, Lisbon, Portugal, Sep. 14-17, Lisbon Portugal},
  booktitle = {Proceedings of IECON 2019, 45th Annual Conference of the IEEE Industrial Electronics Society, Lisbon, Portugal, Sep. 14-17, Lisbon Portugal},
  pages     = {1774 -- 1779},
  subject      = {DC/DC Converter},
  language  = {en}
}
@inproceedings{HimmelstossVotzi,
  author    = {Himmelstoß, Felix and Votzi, Helmut},
  title     = {Simple Inductive Charge Pump},
  series = {Proceedings of 2020 IEEE 14th International Conference on Compatibility, Power Electronics and Power Engineering (CPE-POWERENG), Setubal, Portugal, 1-3 April, 2020},
  booktitle = {Proceedings of 2020 IEEE 14th International Conference on Compatibility, Power Electronics and Power Engineering (CPE-POWERENG), Setubal, Portugal, 1-3 April, 2020},
  pages     = {291 -- 296},
  subject      = {DC/DC Converter},
  language  = {en}
}
@inproceedings{HimmelstossVotzi,
  author    = {Himmelstoß, Felix and Votzi, Helmut},
  title     = {A Floating Double Buck-Boost Converter as Driver for a Permanent Exited DC Machine},
  series = {Proceedings of the 2021 International Conference on Electrical Drives \& Power Electronics (EDPE 2021), 22.-24. September 2021, Dubrovnik, Croatia},
  booktitle = {Proceedings of the 2021 International Conference on Electrical Drives \& Power Electronics (EDPE 2021), 22.-24. September 2021, Dubrovnik, Croatia},
  pages     = {72 -- 77},
  subject      = {DC/DC converter},
  language  = {en}
}
@article{HimmelstossEdelmoser,
  author    = {Himmelstoß, Felix and Edelmoser, Karl},
  title     = {Flyback Converter with Quadratic Pre-Stage},
  series = {WSEAS Transactions of Circuits and Systems, Vol. 19, 2020},
  volume    = {2020},
  journal   = {WSEAS Transactions of Circuits and Systems, Vol. 19, 2020},
  number    = {Vol. 19},
  pages     = {156 -- 163},
  subject      = {DC/DC Converter},
  language  = {en}
}
@inproceedings{HimmelstossVotzi,
  author    = {Himmelstoß, Felix and Votzi, Helmut},
  title     = {Converters to drive two brushed DC machines},
  series = {2021 IEEE 15th International Conference on Compatibility, Power Electronics and Power Engineering (CPE-POWERENG), 14-16 July 2021, Florence, Italy},
  booktitle = {2021 IEEE 15th International Conference on Compatibility, Power Electronics and Power Engineering (CPE-POWERENG), 14-16 July 2021, Florence, Italy},
  pages     = {8},
  subject      = {DC converters},
  language  = {en}
}
@inproceedings{HimmelstossPoepperl,
  author    = {Himmelstoß, Felix and Poepperl, Florian},
  title     = {Inverting Zero-Current-Switching Buck Converter},
  series = {2021 IEEE 19th International Power Electronics and Motion Control Conference (PEMC), 26.-29. April 2021, Glivice, Poland},
  booktitle = {2021 IEEE 19th International Power Electronics and Motion Control Conference (PEMC), 26.-29. April 2021, Glivice, Poland},
  pages     = {108 -- 113},
  subject      = {DC/DC converter},
  language  = {en}
}
@article{HimmelstossEdelmoser,
  author    = {Himmelstoß, Felix and Edelmoser, Karl},
  title     = {Modified Fourth-Order Buck-Boost Converter},
  series = {WSEAS Transactions of Circuits and Systems},
  journal   = {WSEAS Transactions of Circuits and Systems},
  pages     = {33 -- 40},
  subject      = {buck-boost converter},
  language  = {en}
}
@inproceedings{HimmelstossEdelmoser,
  author    = {Himmelstoß, Felix and Edelmoser, Karl},
  title     = {Modified Basic Converters in the Discontinuous Mode},
  series = {2021 IEEE 19th International Power Electronics and Motion Control Conference (PEMC), 26.-29. April 2021, Glivice, Poland},
  booktitle = {2021 IEEE 19th International Power Electronics and Motion Control Conference (PEMC), 26.-29. April 2021, Glivice, Poland},
  pages     = {118 -- 123},
  subject      = {buck-boost converter},
  language  = {en}
}
@article{HimmelstossVotzi,
  author    = {Himmelstoß, Felix and Votzi, Helmut},
  title     = {Converter for the Drive of two Brushed DC motors},
  series = {WSEAS Transactions of Circuits and Systems},
  volume    = {15},
  journal   = {WSEAS Transactions of Circuits and Systems},
  number    = {2020},
  pages     = {249 -- 256},
  subject      = {brushed DC machine},
  language  = {en}
}
@inproceedings{HimmelstossVotziWindisch,
  author    = {Himmelstoß, Felix and Votzi, Helmut and Windisch, Michael},
  title     = {Quadratic DC/DC converter with autotransformer at the output side},
  series = {Proceedings of 2020 IEEE 29th International Symposium on Industrial Electronics (ISIE), Delft, Netherlands, June 17-19, 2020},
  booktitle = {Proceedings of 2020 IEEE 29th International Symposium on Industrial Electronics (ISIE), Delft, Netherlands, June 17-19, 2020},
  pages     = {767 -- 772},
  subject      = {DC/DC Converter},
  language  = {en}
}
@article{YalcinHimmelstoss,
  author    = {Yalcin, Faruk and Himmelstoß, Felix},
  title     = {Boost Converter based 3-phase AC-AC Active Tracking Voltage Regulator Controlled by a Robust Hybrid Control Method},
  series = {Sakarya University Journal of Science},
  volume    = {2022},
  journal   = {Sakarya University Journal of Science},
  number    = {26(1)},
  pages     = {24 -- 37},
  subject      = {AC-AC regulator},
  language  = {en}
}
@inproceedings{HimmelstossJungmayer,
  author    = {Himmelstoß, Felix and Jungmayer, Michael},
  title     = {Zero-Current-Switching Buck Converter},
  series = {Proceedings of 2019 International Conference on Electrical Drives \& Power Electronics (EDPE), Novy Smokovec, Slovakia, 24-26 Sept. 2019},
  booktitle = {Proceedings of 2019 International Conference on Electrical Drives \& Power Electronics (EDPE), Novy Smokovec, Slovakia, 24-26 Sept. 2019},
  pages     = {36 -- 41},
  subject      = {DC/DC Converter},
  language  = {en}
}
@article{HimmelstossEdelmoser,
  author    = {Himmelstoß, Felix and Edelmoser, Karl},
  title     = {Modified Buck-Boost Converter as DC Motor Driver with Continuous Input Current},
  series = {WSEAS Transactions of Circuits and Systems},
  volume    = {2020},
  journal   = {WSEAS Transactions of Circuits and Systems},
  number    = {19},
  pages     = {186 -- 194},
  subject      = {DC/DC converter},
  language  = {en}
}
@article{SchneiderPultarOesterreicheretal.,
  author    = {Schneider, Jaana and Pultar, Marianne and Oesterreicher, Johannes and Bobbili, Madhusudhan Reddy and M{\"u}hleder, Severin and Priglinger, Eleni and Redl, Heinz and Spittler, Andreas and Grillari, Johannes and Holnthoner, Wolfgang},
  title     = {Cre mRNA Is Not Transferred by EVs from Endothelial and Adipose-Derived Stromal/Stem Cells during Vascular Network Formation},
  series = {Int J Mol Sci.},
  volume    = {2021},
  journal   = {Int J Mol Sci.},
  number    = {22(8)},
  pages     = {4050},
  abstract  = {Coculture systems employing adipose tissue-derived mesenchymal stromal/stem cells (ASC) and endothelial cells (EC) represent a widely used technique to model vascularization. Within this system, cell-cell communication is crucial for the achievement of functional vascular network formation. Extracellular vesicles (EVs) have recently emerged as key players in cell communication by transferring bioactive molecules between cells. In this study we aimed to address the role of EVs in ASC/EC cocultures by discriminating between cells, which have received functional EV cargo from cells that have not. Therefore, we employed the Cre-loxP system, which is based on donor cells expressing the Cre recombinase, whose mRNA was previously shown to be packaged into EVs and reporter cells containing a construct of floxed dsRed upstream of the eGFP coding sequence. The evaluation of Cre induced color switch in the reporter system via EVs indicated that there is no EV-mediated RNA transmission either between EC themselves or EC and ASC. However, since Cre mRNA was not found present in EVs, it remains unclear if Cre mRNA is generally not packaged into EVs or if EVs are not taken up by the utilized cell types. Our data indicate that this technique may not be applicable to evaluate EV-mediated cell-to-cell communication in an in vitro setting using EC and ASC. Further investigations will require a functional system showing efficient and specific loading of Cre mRNA or protein into EVs.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@inproceedings{WidhalmGoeschkaKastner,
  author    = {Widhalm, Dominik and Goeschka, Karl M. and Kastner, Wolfgang},
  title     = {Undervolting on wireless sensor nodes: a critical perspective},
  series = {Proceedings of the 23rd International Conference on Distributed Computing and Networking (ICDCN 2022), 4-7 January 2022, Delhi, India},
  booktitle = {Proceedings of the 23rd International Conference on Distributed Computing and Networking (ICDCN 2022), 4-7 January 2022, Delhi, India},
  doi       = {https://doi.org/10.1145/3491003.3491018},
  pages     = {8},
  subject      = {wireless sensor network},
  language  = {en}
}
@article{SchneiderRohringerKapelleretal.,
  author    = {Schneider, Karl H. and Rohringer, Sabrina and Kapeller, Barbara and Grasl, Christian and Kiss, Herbert and Heber, Stefan and Walter, Ingrid and Teuschl, Andreas H. and Podesser, Bruno K. and Bergmeister, Helga},
  title     = {Riboflavin-mediated photooxidation to improve the characteristics of decellularized human arterial small diameter vascular grafts},
  series = {Acta Biomaterialia},
  volume    = {116},
  journal   = {Acta Biomaterialia},
  pages     = {246 -- 258},
  abstract  = {Vascular grafts with a diameter of less than 6 mm are made from a variety of materials and techniques to provide alternatives to autologous vascular grafts. Decellularized materials have been proposed as a possible approach to create extracellular matrix (ECM) vascular prostheses as they are naturally derived and inherently support various cell functions. However, these desirable graft characteristics may be limited by alterations of the ECM during the decellularization process leading to decreased biomechanical properties and hemocompatibility. In this study, arteries from the human placenta chorion were decellularized using two distinct detergents (Triton X-100 or SDS), which differently affect ECM ultrastructure. To overcome biomechanical strength loss and collagen fiber exposure after decellularization, riboflavin-mediated UV (RUV) crosslinking was used to uniformly crosslink the collagenous ECM of the grafts. Graft characteristics and biocompatibility with and without RUV crosslinking were studied in vitro and in vivo. RUV-crosslinked ECM grafts showed significantly improved mechanical strength and smoothening of the luminal graft surfaces. Cell seeding using human endothelial cells revealed no cytotoxic effects of the RUV treatment. Short-term aortic implants in rats showed cell migration and differentiation of host cells. Functional graft remodeling was evident in all grafts. Thus, RUV crosslinking is a preferable tool to improve graft characteristics of decellularized matrix conduits.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@inproceedings{HimmelstossEdelmoser,
  author    = {Himmelstoß, Felix and Edelmoser, Karl},
  title     = {Quadratic Flyback Converter},
  series = {Proceedings of PCIM Europe digital days 2020; International Exhibition and Conference for Power Electronics, Intelligent Motion, Renewable Energy and Energy Management, Nuernberg, Germany, 7-8 July, 2020},
  booktitle = {Proceedings of PCIM Europe digital days 2020; International Exhibition and Conference for Power Electronics, Intelligent Motion, Renewable Energy and Energy Management, Nuernberg, Germany, 7-8 July, 2020},
  pages     = {6},
  subject      = {Quadratic Power Converter},
  language  = {en}
}
@article{Holnthoner,
  author    = {Holnthoner, Wolfgang},
  title     = {Adipose-tissue-derived therapeutic cells in their natural environment as an autologous cell therapy strategy: the microtissue-stromal vascular fraction},
  series = {Eur Cell Mater.},
  volume    = {2019},
  journal   = {Eur Cell Mater.},
  number    = {Feb, 37},
  pages     = {113 -- 133},
  abstract  = {The prerequisite for a successful clinical use of autologous adipose-tissue-derived cells is the highest possible regenerative potential of the applied cell population, the stromal vascular fraction (SVF). Current isolation methods depend on high enzyme concentration, lysis buffer, long incubation steps and mechanical stress, resulting in single cell dissociation. The aim of the study was to limit cell manipulation and obtain a derivative comprising therapeutic cells (microtissue-SVF) without dissociation from their natural extracellular matrix, by employing a gentle good manufacturing practice (GMP)-grade isolation. The microtissue-SVF yielded larger numbers of viable cells as compared to the improved standard-SVF, both with low enzyme concentration and minimal dead cell content. It comprised stromal tissue compounds (collagen, glycosaminoglycans, fibroblasts), capillaries and vessel structures (CD31+, smooth muscle actin+). A broad range of cell types was identified by surface-marker characterisation, including mesenchymal, haematopoietic, pericytic, blood and lymphatic vascular and epithelial cells. Subpopulations such as supra-adventitial adipose-derived stromal/stem cells and endothelial progenitor cells were significantly more abundant in the microtissue-SVF, corroborated by significantly higher potency for angiogenic tube-like structure formation in vitro. The microtissue-SVF showed the characteristic phenotype and tri-lineage mesenchymal differentiation potential in vitro and an immunomodulatory and pro-angiogenic secretome. In vivo implantation of the microtissue-SVF combined with fat demonstrated successful graft integration in nude mice. The present study demonstrated a fast and gentle isolation by minor manipulation of liposuction material, achieving a therapeutically relevant cell population with high vascularisation potential and immunomodulatory properties still embedded in a fraction of its original matrix.},
  subject      = {Adipose-tissue},
  language  = {en}
}
@inproceedings{WidhalmGoeschkaKastner,
  author    = {Widhalm, Dominik and Goeschka, Karl M. and Kastner, Wolfgang},
  title     = {Node-level indicators of soft faults in wireless sensor networks},
  series = {Proceedings of the 40th International Symposium on Reliable Distributed Systems (SRDS 2021), 20-23 September 2021, Chicago, USA},
  booktitle = {Proceedings of the 40th International Symposium on Reliable Distributed Systems (SRDS 2021), 20-23 September 2021, Chicago, USA},
  publisher = {IEEE},
  pages     = {13 -- 22},
  subject      = {wireless sensor network},
  language  = {en}
}
@article{Himmelstoss,
  author    = {Himmelstoß, Felix},
  title     = {Improved positive output voltage super-lift Boost converter},
  series = {WSEAS TRANSACTIONS on POWER SYSTEMS},
  volume    = {2022},
  journal   = {WSEAS TRANSACTIONS on POWER SYSTEMS},
  number    = {Vol. 17},
  pages     = {68 -- 75},
  subject      = {DC/DC converter},
  language  = {en}
}
@article{StrohmeierHofmannJacaketal.,
  author    = {Strohmeier, Karin and Hofmann, Martina and Jacak, Jaroslaw and Narzt, Marie-Sophie and Wahlmueller, Marlene and Mairhofer, Mario and Sch{\"a}dl, Barbara and Holnthoner, Wolfgang and Barsch, Martin and Sandhofer, Matthias and Wolbank, Susanne and Priglinger, Eleni},
  title     = {Multi-Level Analysis of Adipose Tissue Reveals the Relevance of Perivascular Subpopulations and an Increased Endothelial Permeability in Early-Stage Lipedema},
  series = {Biomedicines},
  volume    = {2022},
  journal   = {Biomedicines},
  number    = {10(5)},
  pages     = {1163},
  abstract  = {Lipedema is a chronic, progressive disease of adipose tissue with unknown etiology. Based on the relevance of the stromal vascular fraction (SVF) cell population in lipedema, we performed a thorough characterization of subcutaneous adipose tissue, SVF isolated thereof and the sorted populations of endothelial cells (EC), pericytes and cultured adipose-derived stromal/stem cells (ASC) of early-stage lipedema patients. We employed histological and gene expression analysis and investigated the endothelial barrier by immunofluorescence and analysis of endothelial permeability in vitro. Although there were no significant differences in histological stainings, we found altered gene expression of factors relevant for local estrogen metabolism (aromatase), preadipocyte commitment (ZNF423) and immune cell infiltration (CD11c) in lipedema on the tissue level, as well as in distinct cellular subpopulations. Machine learning analysis of immunofluorescence images of CD31 and ZO-1 revealed a morphological difference in the cellular junctions of EC cultures derived from healthy and lipedema individuals. Furthermore, the secretome of lipedema-derived SVF cells was sufficient to significantly increase leakiness of healthy human primary EC, which was also reflected by decreased mRNA expression of VE-cadherin. Here, we showed for the first time that the secretome of SVF cells creates an environment that triggers endothelial barrier dysfunction in early-stage lipedema. Moreover, since alterations in gene expression were detected on the cellular and/or tissue level, the choice of sample material is of high importance in elucidating this complex disease.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@inproceedings{HimmelstossEdelmoser,
  author    = {Himmelstoß, Felix and Edelmoser, Karl},
  title     = {Zero-Current-Switching Boost Converter, Power Conversion and Intelligent Motion},
  series = {Proceedings of PCIM 2019, Nuernberg, Germany, May 7-9, 2019},
  booktitle = {Proceedings of PCIM 2019, Nuernberg, Germany, May 7-9, 2019},
  isbn      = {978-3-8007-4938-6},
  pages     = {1686 -- 1691},
  subject      = {Discontinuous Conduction Mode},
  language  = {en}
}
@article{TriskoFleckKauetal.,
  author    = {Trisko, Johanna and Fleck, Johanna and Kau, Silvio and Oesterreicher, Johannes and Holnthoner, Wolfgang},
  title     = {Lymphatic and Blood Endothelial Extracellular Vesicles: A Story Yet to Be Written},
  series = {Life},
  volume    = {2022},
  journal   = {Life},
  number    = {12(5)},
  pages     = {654},
  abstract  = {Extracellular vesicles (EVs), such as exosomes, microvesicles, and apoptotic bodies, are cell-derived, lipid bilayer-enclosed particles mediating intercellular communication and are therefore vital for transmitting a plethora of biological signals. The vascular endothelium substantially contributes to the circulating particulate secretome, targeting important signaling pathways that affect blood cells and regulate adaptation and plasticity of endothelial cells in a paracrine manner. Different molecular signatures and functional properties of endothelial cells reflect their heterogeneity among different vascular beds and drive current research to understand varying physiological and pathological effects of blood and lymphatic endothelial EVs. Endothelial EVs have been linked to the development and progression of various vascular diseases, thus having the potential to serve as biomarkers and clinical treatment targets. This review aims to provide a brief overview of the human vasculature, the biology of extracellular vesicles, and the current knowledge of endothelium-derived EVs, including their potential role as biomarkers in disease development.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@article{SayerZandriniMarkovicetal.,
  author    = {Sayer, Simon and Zandrini, Tommaso and Markovic, Marica and Van Hoorick, Jasper and Van Vlierberghe, Sandra and Baudis, Stefan and Holnthoner, Wolfgang and Ovsianikov, Aleksandr},
  title     = {Guiding cell migration in 3D with high-resolution photografting},
  series = {Scientific Reports},
  volume    = {2022},
  journal   = {Scientific Reports},
  number    = {12(1), 10196},
  pages     = {8626},
  abstract  = {Multi-photon lithography (MPL) has proven to be a suitable tool to precisely control the microenvironment of cells in terms of the biochemical and biophysical properties of the hydrogel matrix. In this work, we present a novel method, based on multi-photon photografting of 4,4′-diazido-2,2′-stilbenedisulfonic acid (DSSA), and its capabilities to induce cell alignment, directional cell migration and endothelial sprouting in a gelatin-based hydrogel matrix. DSSA-photografting allows for the fabrication of complex patterns at a high-resolution and is a biocompatible, universally applicable and straightforward process that is comparably fast. We have demonstrated the preferential orientation of human adipose-derived stem cells (hASCs) in response to a photografted pattern. Co-culture spheroids of hASCs and human umbilical vein endothelial cells (HUVECs) have been utilized to study the directional migration of hASCs into the modified regions. Subsequently, we have highlighted the dependence of endothelial sprouting on the presence of hASCs and demonstrated the potential of photografting to control the direction of the sprouts. MPL-induced DSSA-photografting has been established as a promising method to selectively alter the microenvironment of cells.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@inproceedings{HimmelstossJungmayer,
  author    = {Himmelstoß, Felix and Jungmayer, Michael},
  title     = {A Family of Modified Converters with Limited Duty Cycle},
  series = {Proceedings of the 2021 International Aegean Conference on Electrical Machines and Power Electronics (ACEMP) \& 2021 International Conference on Optimization of Electrical and Electronic Equipment (OPTIM), 2.-3. September 2021, Brasov, Rumania},
  booktitle = {Proceedings of the 2021 International Aegean Conference on Electrical Machines and Power Electronics (ACEMP) \& 2021 International Conference on Optimization of Electrical and Electronic Equipment (OPTIM), 2.-3. September 2021, Brasov, Rumania},
  publisher = {IEEE},
  doi       = {https://doi.org/10.1109/OPTIM-ACEMP50812.2021.9590064},
  pages     = {246 -- 253},
  subject      = {modified converters},
  language  = {en}
}
@article{WidhalmGoeschkaKastner,
  author    = {Widhalm, Dominik and Goeschka, Karl M. and Kastner, Wolfgang},
  title     = {An open-source wireless sensor node platform with active node-level reliability for monitoring applications},
  series = {Sensors},
  volume    = {2021},
  journal   = {Sensors},
  number    = {Volume 21, Issue 22, Article-No. 7613},
  subject      = {sensor node},
  language  = {en}
}
@article{Himmelstoss,
  author    = {Himmelstoß, Felix},
  title     = {Virtual Laboratory: Switching of A Nearly Resistive Load},
  series = {International Journal of Education and Learning Systems},
  volume    = {2021},
  journal   = {International Journal of Education and Learning Systems},
  number    = {Vol. 6},
  pages     = {13 -- 19},
  subject      = {virtual laboratory},
  language  = {en}
}
@article{YalcinHimmelstoss,
  author    = {Yalcin, Faruk and Himmelstoß, Felix},
  title     = {Buck-type Single-phase AC-AC Active Tracking Voltage Regulator Controlled by an Enhanced Hybrid Control Method},
  series = {Sakarya University Journal of Science},
  volume    = {2021},
  journal   = {Sakarya University Journal of Science},
  number    = {25},
  pages     = {926 -- 937},
  subject      = {AC-AC regulator},
  language  = {en}
}
@phdthesis{Widhalm,
  author    = {Widhalm, Dominik},
  title     = {Sensor Node Fault Detection in Wireless Sensor Networks: An Immune-inspired Approach},
  school      = {Fachhochschule Technikum Wien},
  subject      = {fault detection},
  language  = {en}
}
@inproceedings{WidhalmGoeschkaKastner,
  author    = {Widhalm, Dominik and Goeschka, Karl M. and Kastner, Wolfgang},
  title     = {Is Arduino a suitable platform for sensor nodes?},
  series = {Proceedings of the 47th Annual Conference of the IEEE Industrial Electronics Society (IECON 2021), 13-16 October 2021, Toronto, Canada},
  booktitle = {Proceedings of the 47th Annual Conference of the IEEE Industrial Electronics Society (IECON 2021), 13-16 October 2021, Toronto, Canada},
  publisher = {IEEE},
  doi       = {doi: 10.1109/IECON48115.2021.9589479},
  pages     = {6},
  subject      = {Arduino},
  language  = {en}
}
@article{HimmelstossEdelmoser,
  author    = {Himmelstoß, Felix and Edelmoser, Karl},
  title     = {Virtual three-phase laboratory exercise during pandemic situation},
  series = {WSEAS TRANSACTIONS on ADVANCES in ENGINEERING EDUCATION},
  volume    = {2022},
  journal   = {WSEAS TRANSACTIONS on ADVANCES in ENGINEERING EDUCATION},
  pages     = {6},
  subject      = {virtual laboratory},
  language  = {en}
}
@inproceedings{HimmelstossVotzi,
  author    = {Himmelstoß, Felix and Votzi, Helmut},
  title     = {Modified d(2-d)/(1-d)2-Converter},
  series = {Proceedings of the Power Conversion and Intelligent Motion Conference (PCIM) 2022, 10-12 May, 2022 Nurenberg, Germany},
  booktitle = {Proceedings of the Power Conversion and Intelligent Motion Conference (PCIM) 2022, 10-12 May, 2022 Nurenberg, Germany},
  doi       = {doi: 10.30420/565822200},
  pages     = {1446 -- 1453},
  subject      = {DC/DC converter},
  language  = {en}
}
@inproceedings{HimmelstossVotzi,
  author    = {Himmelstoß, Felix and Votzi, Helmut},
  title     = {A family of quadratic DC/DC converters with one low-side switch and a tapped inductor at the output side},
  series = {Aegean Conference on Electrical Machines and Power Electronics \& Optimization of Electrical \& Electronic Equipment Conference, Istanbul Turkey, August, 27 - 29, 2019},
  booktitle = {Aegean Conference on Electrical Machines and Power Electronics \& Optimization of Electrical \& Electronic Equipment Conference, Istanbul Turkey, August, 27 - 29, 2019},
  pages     = {6},
  subject      = {DC/DC Converter},
  language  = {en}
}
@article{YalcinHimmelstoss,
  author    = {Yalcin, Faruk and Himmelstoß, Felix},
  title     = {Single-phase Boost-type Active Tracking AC-AC Voltage Regulator with an Improved Hybrid Control Technique},
  series = {Duzce University Journal of Science and Technology},
  volume    = {2022},
  journal   = {Duzce University Journal of Science and Technology},
  number    = {10, issue 1},
  pages     = {139 -- 153},
  subject      = {Boost converter},
  language  = {en}
}
@article{RothbauerByrneSchobesbergeretal.,
  author    = {Rothbauer, Mario and Byrne, Ruth A. and Schobesberger, Silvia and Olmos Calvo, Isabel and Fischer, Anita and Reihs, Eva I. and Spitz, Sarah and Bachmann, Barbara and Sevelda, Florian and Holinka, Johannes and Holnthoner, Wolfgang and Redl, Heinz and Toegel, Stefan and Windhager, Reinhard and Kiener, Hans P. and Ertl, Peter},
  title     = {Establishment of a human three-dimensional chip-based chondro-synovial coculture joint model for reciprocal cross talk studies in arthritis research},
  series = {Lab on a Chip},
  volume    = {2021},
  journal   = {Lab on a Chip},
  number    = {21},
  pages     = {4128 -- 4143},
  abstract  = {Rheumatoid arthritis is characterised by a progressive, intermittent inflammation at the synovial membrane, which ultimately leads to the destruction of the synovial joint. The synovial membrane as the joint capsule's inner layer is lined with fibroblast-like synoviocytes that are the key player supporting persistent arthritis leading to bone erosion and cartilage destruction. While microfluidic models that model molecular aspects of bone erosion between bone-derived cells and synoviocytes have been established, RA's synovial-chondral axis has not yet been realised using a microfluidic 3D model based on human patient in vitro cultures. Consequently, we established a chip-based three-dimensional tissue coculture model that simulates the reciprocal cross talk between individual synovial and chondral organoids. When co-cultivated with synovial organoids, we could demonstrate that chondral organoids induce a higher degree of cartilage physiology and architecture and show differential cytokine response compared to their respective monocultures highlighting the importance of reciprocal tissue-level cross talk in the modelling of arthritic diseases.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@article{YalcinHimmelstoss,
  author    = {Yalcin, Faruk and Himmelstoß, Felix},
  title     = {Three-phase Active Tracking AC-AC Voltage Regulator based on Buck Converter with an Efficient Hybrid Control Technique},
  series = {D{\"u}zce University Journal of Science \& Technology},
  volume    = {2022},
  journal   = {D{\"u}zce University Journal of Science \& Technology},
  number    = {10},
  pages     = {537 -- 554},
  subject      = {buck converter},
  language  = {en}
}
@inproceedings{Himmelstoss,
  author    = {Himmelstoß, Felix},
  title     = {Controller design of a Buck converter with the help of LTSpice},
  series = {Proceedings of the International Asian Congress of Contemporary Sciences, 27-29 May, 2022, Van, Turkiye},
  booktitle = {Proceedings of the International Asian Congress of Contemporary Sciences, 27-29 May, 2022, Van, Turkiye},
  pages     = {195 -- 202},
  subject      = {DC/DC converter},
  language  = {en}
}
@misc{LangerNemecKollmitzeretal.,
  author    = {Langer, Sarah and Nemec, Iris and Kollmitzer, Josef and Scherer, Matthias and Martinek, Johannes},
  title     = {Vergleich des decompositionierten und des {\"u}berlagerten Elektromyogramms zur Analyse der Muskelerm{\"u}dung},
  abstract  = {Ziel dieser Studie war das {\"u}berlagerte Elektromyogramm (ueEMG) und das decompositionierte (dEMG) auf deren Reliabilit{\"a}t und Aussagekraft zu {\"u}berpr{\"u}fen. Hierf{\"u}r vollzogen zehn gesunde m{\"a}nnliche Probanden zu drei Testzeitpunkten isometrische Erm{\"u}dungsmessungen. Hintergrund Bei der Messung des ueEMG werden die Motor Units Aktionspotentiale (MUAPS) elektrisch {\"u}berlagert. Physiologische Muskelerm{\"u}dung zeigt sich hier unter anderem in der Ver{\"a}nderung des Frequenzspektrums und der Signalamplitude. Letzteres steigt bei Erm{\"u}dung an, wohingegen die mediane Frequenz (MF) sinkt. Eine weitere M{\"o}glichkeit die Muskelerm{\"u}dung mittels Oberfl{\"a}chen-EMG zu ermitteln ist die Anwendung des dEMGs. Dieses erm{\"o}glicht mithilfe einer Mustererkennungssoftware einzelne MUAPS zu erkennen. Studien zeigten, dass aktive Motor Units (MU) bei wiederholten oder anhaltenden submaximalen Kontraktionen als Muskelerm{\"u}dung ihre Feuerungsrate erh{\"o}hen und neue MU rekrutiert werden. Bisher wurden diese Methoden jeweils einzeln betrachtet. Um sicherzustellen welcher Ansatz f{\"u}r klinische Daten geeigneter ist, wurden Datens{\"a}tze zu beiden Methoden gleichzeitig generiert und hinsichtlich ihrer Aussagekraft und Wiederholbarkeit mit statistischen Mitteln verglichen.},
  subject      = {Elektromyogramm},
  language  = {de}
}