@techreport{Pasteka,
  author    = {Pasteka, Richard},
  title     = {Der Standard, "Eine Lunge, die Beatmungsger{\"a}te testet", 2019, Vienna, Austria.},
  subject      = {Lungensimulation},
  language  = {de}
}
@misc{Pasteka,
  author    = {Pasteka, Richard},
  title     = {International Lecture, University of Tr{\´a}s-os-Montes and Alto Douro, Portugal, "Human Respiratory System Modelling"},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@inproceedings{PastekaForjan,
  author    = {Pasteka, Richard and Forjan, Mathias},
  title     = {Actively breathing mechanical lung simulator development and preliminary measurements},
  series = {IFMBE,volume 65; EMBEC \& NBC 2017},
  booktitle = {IFMBE,volume 65; EMBEC \& NBC 2017},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@article{PastekaSchoellbauerSantosdaCostaetal.,
  author    = {Pasteka, Richard and Sch{\"o}llbauer, Lara Alina and Santos da Costa, Joao Pedro and Kolar, Radim and Forjan, Mathias},
  title     = {Experimental Evaluation of Dry Powder Inhalers During In- and Exhalation Using a Model of the Human Respiratory System (xPULM™)},
  series = {Pharmaceutics},
  volume    = {2022},
  journal   = {Pharmaceutics},
  number    = {14/3},
  pages     = {15},
  abstract  = {Dry powder inhalers are used by a large number of patients worldwide to treat respiratory diseases. The objective of this work is to experimentally investigate changes in aerosol particle diameter and particle number concentration of pharmaceutical aerosols generated by four dry powder inhalers under realistic inhalation and exhalation conditions. To simulate patients undergoing inhalation therapy, the active respiratory system model (xPULM™) was used. A mechanical upper airway model was developed, manufactured, and introduced as a part of the xPULM™ to represent the human upper respiratory tract with high fidelity. Integration of optical aerosol spectrometry technique into the setup allowed for evaluation of pharmaceutical aerosols. The results show that there is a significant difference (p < 0.05) in mean particle diameter between inhaled and exhaled particles with the majority of the particles depositing in the lung, while particles with the size of (>0.5 μm) are least influenced by deposition mechanisms. The fraction of exhaled particles ranges from 2.13\% (HandiHaler®) over 2.94\% (BreezHaler®), and 6.22\% (Turbohaler®) to 10.24\% (Ellipta®). These values are comparable to previously published studies. Furthermore, the mechanical upper airway model increases the resistance of the overall system and acts as a filter for larger particles (>3 μm). In conclusion, the xPULM™ active respiratory system model is a viable option for studying interactions of pharmaceutical aerosols and the respiratory tract regarding applicable deposition mechanisms. The model strives to support the reduction of animal experimentation in aerosol research and provides an alternative to experiments with human subjects.},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@article{PastekaForjanSauermannetal.,
  author    = {Pasteka, Richard and Forjan, Mathias and Sauermann, Stefan and Drauschke, Andreas},
  title     = {Electro-mechanical Lung Simulator Using Polymer and Organic Human Lung Equivalents for Realistic Breathing Simulation},
  series = {Scientific Reports},
  volume    = {Vol 9},
  journal   = {Scientific Reports},
  number    = {No. 1},
  pages     = {Article number: 19778},
  abstract  = {Simulation models in respiratory research are increasingly used for medical product development and testing, especially because in-vivo models are coupled with a high degree of complexity and ethical concerns. This work introduces a respiratory simulation system, which is bridging the gap between the complex, real anatomical environment and the safe, cost-effective simulation methods. The presented electro-mechanical lung simulator, xPULM, combines in-silico, ex-vivo and mechanical respiratory approaches by realistically replicating an actively breathing human lung. The reproducibility of sinusoidal breathing simulations with xPULM was verified for selected breathing frequencies (10-18 bpm) and tidal volumes (400-600 ml) physiologically occurring during human breathing at rest. Human lung anatomy was modelled using latex bags and primed porcine lungs. High reproducibility of flow and pressure characteristics was shown by evaluating breathing cycles (nTotal = 3273) with highest standard deviation |3σ| for both, simplified lung equivalents (μV˙ = 23.98 ± 1.04 l/min, μP = -0.78 ± 0.63 hPa) and primed porcine lungs (μV˙ = 18.87 ± 2.49 l/min, μP = -21.13 ± 1.47 hPa). The adaptability of the breathing simulation parameters, coupled with the use of porcine lungs salvaged from a slaughterhouse process, represents an advancement towards anatomically and physiologically realistic modelling of human respiration.},
  subject      = {Breathing Simulation},
  language  = {en}
}
@misc{Pasteka,
  author    = {Pasteka, Richard},
  title     = {International Week Turku, "Hands-on learning and research applications"},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@misc{PastekaForjanDrauschke,
  author    = {Pasteka, Richard and Forjan, Mathias and Drauschke, Andreas},
  title     = {Comparison of breathing patterns for aerosol inhalation using an electro-mechanical lung simulator},
  series = {ALTEX Proceedings - EUSAAT 2018, Linz},
  journal   = {ALTEX Proceedings - EUSAAT 2018, Linz},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@misc{ForjanPastekaDrauschke,
  author    = {Forjan, Mathias and Pasteka, Richard and Drauschke, Andreas},
  title     = {Lung simulation - an alterna� tive approach to animal testing for applications in aerosol and respiratory research},
  series = {ALTEX Proceedings - EUSAAT 2018, Linz},
  journal   = {ALTEX Proceedings - EUSAAT 2018, Linz},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@misc{Pasteka,
  author    = {Pasteka, Richard},
  title     = {Applications of Biomedical Engineering in Respiratory Care},
  subject      = {Biomedical Engineering},
  language  = {en}
}
@inproceedings{PastekaForjan,
  author    = {Pasteka, Richard and Forjan, Mathias},
  title     = {Changes of particle deposition caused by different breathing patterns during active lung simulation},
  series = {41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019},
  booktitle = {41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019},
  organization    = {IEEE},
  pages     = {4969 -- 4972},
  subject      = {Lung Simulation},
  language  = {en}
}