@article{JesenbergerZmajkovicovaCatalanottietal., author = {Jesenberger, Veronika and Zmajkovicova, Katarina and Catalanotti, Federica and Baumgartner, Christian and Reyes, Gloria Ximena and Baccarini, Manuela}, title = {MEK1 is required for PTEN membrane recruitment, AKT regulation, and the maintenance of peripheral tolerance}, series = {Mol. Cell}, volume = {2013}, journal = {Mol. Cell}, number = {50}, pages = {43 -- 55}, abstract = {The Raf/MEK/ERK and PI3K/Akt pathways are prominent effectors of oncogenic Ras. These pathways negatively regulate each other, but the mechanism involved is incompletely understood. We now identify MEK1 as an essential regulator of lipid/protein phosphatase PTEN, through which it controls phosphatidylinositol-3-phosphate accumulation and AKT signaling. MEK1 ablation stabilizes AKT activation and, in vivo, causes a lupus-like autoimmune disease and myeloproliferation. Mechanistically, MEK1 is necessary for PTEN membrane recruitment as part of a ternary complex containing the multidomain adaptor MAGI1. Complex formation is independent of MEK1 kinase activity but requires phosphorylation of T292 on MEK1 by activated ERK. Thus, inhibiting the ERK pathway reduces PTEN membrane recruitment, increasing phosphatidylinositol-3-phosphate accumulation and AKT activation. Our data offer a conceptual framework for the observation that activation of the PI3K pathway frequently mediate resistance to MEK inhibitors and for the promising results obtained by combined MEK/PI3K inhibition in preclinical cancer models.}, subject = {MEK1 pathway}, language = {en} } @article{ButaDavidDresseletal., author = {Buta, Christiane and David, Robert and Dressel, Ralf and Emgard, Mia and Fuchs, Christiane and Gross, Ulrike and Healy, Lyn and Hescheler, J{\"u}rgen and Kolar, Roman and Martin, Ulrich and Mikkers, Harald and M{\"u}ller, Franz-Josef and Schneider, Rebekka and Seiler, Andrea and Spielmann, Horst and Weitzer, Georg}, title = {REconsidering pluripotency tests: do we still need teratoma assays?}, series = {Stem Cell Research}, volume = {11}, journal = {Stem Cell Research}, number = {1}, pages = {552 -- 562}, subject = {Assay}, language = {en} } @article{DungelTeuschlBanerjeeetal., author = {Dungel, Peter and Teuschl, Andreas and Banerjee, Asmita and Paier-Pourani, Jamile and Redl, Heinz and Kozlov, Andrey}, title = {Impact of mitochondria on nitrite metabolism in HL-1 cardiomyocytes}, series = {Frontiers in Physiology}, journal = {Frontiers in Physiology}, number = {4}, subject = {Nitrite}, language = {en} } @article{TeuschlvanGriensvenRedl, author = {Teuschl, Andreas and van Griensven, Martijn and Redl, Heinz}, title = {Sericin removal from raw Bombys mori silk scaffolds of high hierarchical order}, series = {Tissue Eng Part C Methods}, journal = {Tissue Eng Part C Methods}, subject = {Scaffold}, language = {en} } @inproceedings{GhaemiSchneider, author = {Ghaemi, Sara and Schneider, Simon}, title = {Potential analysis of residential Demand Response using GridLAB-D}, series = {IECON 2013 - 39th Annual Conference of the IEEE Industrial Electronics Society}, booktitle = {IECON 2013 - 39th Annual Conference of the IEEE Industrial Electronics Society}, pages = {8039 -- 8045}, subject = {Potential Analysis}, language = {en} } @misc{Pucher, author = {Pucher, Robert}, title = {Computer Science}, subject = {Project Based Learning}, language = {en} } @inproceedings{HorauerSchusterBalog, author = {Horauer, Martin and Schuster, Harald and Balog, Peter}, title = {Experimental Assessment of the Clique Problem in FlexRay}, series = {Proceedings of the 8th ASME/IEEE International Conference on Mechatronic and Embedded Systems and Applications, Portland OR, USA, Aug. 04-07, 2013}, booktitle = {Proceedings of the 8th ASME/IEEE International Conference on Mechatronic and Embedded Systems and Applications, Portland OR, USA, Aug. 04-07, 2013}, subject = {Embedded Systems}, language = {en} } @inproceedings{WagnerWolffSchaefferetal., author = {Wagner, Richard and Wolff, Peter and Schaeffer, Klaus and Praus, Friedrich}, title = {Ambient Assitive Technologies: The mobile robot P3AAT}, series = {Proceedings of the Austrian Robotics Workshop (ARW-13), May 2013, Vienna}, booktitle = {Proceedings of the Austrian Robotics Workshop (ARW-13), May 2013, Vienna}, subject = {Assistive Technologies}, language = {en} } @inproceedings{IsaacsPraus, author = {Isaacs, Richard and Praus, Friedrich}, title = {Design \& development of a prototype android app for a KNX home}, series = {KNX Scientific Conference}, booktitle = {KNX Scientific Conference}, subject = {Embedded Systems}, language = {en} } @inproceedings{SamardzijaPraus, author = {Samardzija, Luka and Praus, Friedrich}, title = {ANT goes KNX - an open platform gateway for ANT and KNX}, series = {KNX Scientific Conference}, booktitle = {KNX Scientific Conference}, subject = {Embedded Systems}, language = {en} } @inproceedings{VeiglWeissIbanezetal., author = {Veigl, Christoph and Weiß, Christoph and Ibanez, David and Soria-Frisch, Aureli and Carbone, Andrea}, title = {Model-based Design of Novel Human-Computer Interfaces, The Assistive Technology Rapid Integration and Construction Set (AsTeRICS)}, series = {4th IEEE Biosignals and Biorobotics Conference (ISSNIP 2013), Rio de Janeiro (Brasil), 18-20 February 2013}, booktitle = {4th IEEE Biosignals and Biorobotics Conference (ISSNIP 2013), Rio de Janeiro (Brasil), 18-20 February 2013}, subject = {Assistive Technologies}, language = {en} } @inproceedings{WenzlSchusterObermayeretal., author = {Wenzl, Matthias and Schuster, Harald and Obermayer, Christian and Balog, Peter}, title = {EMBEDDED MULTI CORE VIRTUAL PROTOTYPING FOR SOFTWARE ENGINEERS}, series = {roceedings of the ASME 2013 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference IDETC/CIE 2013, August 4-7, 2013, Portland, Oregon, USA}, booktitle = {roceedings of the ASME 2013 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference IDETC/CIE 2013, August 4-7, 2013, Portland, Oregon, USA}, subject = {Embedded Systems}, language = {en} } @inproceedings{WirsingReichlEhrleretal., author = {Wirsing, Stephan and Reichl, Wolfgang and Ehrler, Matthias and Malleck, H.}, title = {Energy and Communication Access Networks — Bridging the Divide: Approaches for Policy Intervention}, series = {Proceedings of Smart Grid Technology, Economics and Policies (SG-TEP), 2012}, booktitle = {Proceedings of Smart Grid Technology, Economics and Policies (SG-TEP), 2012}, subject = {Energy}, language = {en} } @misc{WirsingReichlEhrleretal., author = {Wirsing, Stephan and Reichl, Wolfgang and Ehrler, Matthias and Malleck, H.}, title = {Energy and Communication Access Networks: Bridging the Divide}, subject = {Energy}, language = {en} } @inproceedings{Beneder, author = {Beneder, Roman}, title = {Innovative concepts for Embedded Systems courses}, series = {FHK - 7th Association of Austrian Universities of Applied Sciences, Dornbirn, Austria, April 2013}, booktitle = {FHK - 7th Association of Austrian Universities of Applied Sciences, Dornbirn, Austria, April 2013}, subject = {Embedded Systems}, language = {en} } @misc{FriessnikSommer, author = {Friessnik, Erhard and Sommer, Thomas}, title = {Reverse Engineering, Forensik und Repackaging von Android Apps}, subject = {Mobile Application}, language = {en} } @inproceedings{Wenzl, author = {Wenzl, Matthias}, title = {Evaluating best practices for teaching multi-core programming}, series = {Ireland International Conference on Education (IIEC-2012), October 29-31, 2012, Dublin, Ireland}, booktitle = {Ireland International Conference on Education (IIEC-2012), October 29-31, 2012, Dublin, Ireland}, subject = {Embedded Systems}, language = {en} } @misc{PucherSchmoellebeck, author = {Pucher, Robert and Schm{\"o}llebeck, Fritz}, title = {Improving the Usability of Campus Information Systems}, subject = {Information System}, language = {en} } @inproceedings{PucherSchmoellebeck, author = {Pucher, Robert and Schm{\"o}llebeck, Fritz}, title = {Improving the Usability of Campus Information Systems}, series = {Proceedings of the 7th International Technology, Education and Development Conference (INTED 2013)}, booktitle = {Proceedings of the 7th International Technology, Education and Development Conference (INTED 2013)}, subject = {Information System}, language = {en} } @misc{SchmidHatakRoessl, author = {Schmid, Judith and Hatak, Isabella and R{\"o}ßl, Dietmar}, title = {Entrepreneurial Marketing as a Success Factor}, subject = {Marketing}, language = {en} }