@article{MandlMeyerspeerReicheletal., author = {Mandl, Thomas and Meyerspeer, Martin and Reichel, Martin and Kern, Helmut and Hofer, Christian and Mayr, Winfried and Moser, Ewald}, title = {Functional electrical stimulation of long-term denervated, degenerated human skeletal muscle: estimating activation using T2-parameter magnetic resonance imaging methods}, series = {Artif Organs}, journal = {Artif Organs}, number = {32(8)}, pages = {604 -- 608}, subject = {Electrical Stimulation}, language = {en} } @misc{TeuschlFuchs, author = {Teuschl, Andreas and Fuchs, Christiane}, title = {Bioreactors in Musculoskeletal Tissue Engineering}, subject = {Bioreactor}, language = {en} } @misc{HeherTomaschMaleineretal., author = {Heher, Philipp and Tomasch, Janine and Maleiner, Babette and Redl, Heinz and Fuchs, Christiane}, title = {The Importance of Biomechanical Cues for In Vitro Skeletal Myogenesis}, subject = {In Vitro}, language = {en} } @misc{Tomasch, author = {Tomasch, Janine}, title = {Generation of 3D skeletal muscle-like scaffolds via the application of mechanical stimuli}, subject = {Scaffold}, language = {en} } @article{SchuhHeherWeihsetal., author = {Schuh, Christina and Heher, Philipp and Weihs, Anna and Fuchs, Christiane and Gabriel, Christian and Wolbank, Susanne and Mittermayr, Rainer and Redl, Heinz and R{\"u}nzler, Dominik and Teuschl, Andreas}, title = {In vitro extracorporeal shock wave treatment enhances stemness and preserves multipotency of rat and human adipose-derived stem cells}, series = {Journal of Cytotherapy}, journal = {Journal of Cytotherapy}, subject = {Shockwave}, language = {en} } @misc{MandlDohnalStickleretal., author = {Mandl, Thomas and Dohnal, Fahdi and Stickler, Yvonne and Martinek, Johannes and Reichel, Martin and Mayr, Winfried and Rattay, Frank}, title = {FE-Modellierung f{\"u}r Implantate als Alternative zur transkutanen Elektrostimulation des langzeitdenervierten Oberschenkels}, subject = {Implants}, language = {de} } @misc{KornfeindBlahaPeuschletal., author = {Kornfeind, P. and Blaha, A. and Peuschl, M. and Reichel, Martin and Sabo, Anton}, title = {2-Komponentenplattform zur Erfassung der Stemmbrettkr{\"a}fte am Ruderergometer und im Ruderboot}, subject = {Sport}, language = {de} } @misc{KueenburgTeuschl, author = {K{\"u}enburg, Bernhard and Teuschl, Andreas}, title = {Regenerative silk ligament: scale up and regulatory strategy of a textile engineered silk implant for tissue regeneration of injured human ACL (anterior cruciate ligament)}, abstract = {61 a93591 27-SY-1 Regenerative silk ligament: scale up and regulatory strategy of a textile engineered silk implant for tissue regeneration of injured human ACL (anterior cruciate ligament) Bernhard K{\"u}enburg,Andreas Teuschl MorphoMed, Austria In the USA around 370.000 annual ACL ruptures in the predominately young population (age 18-30) following sport injuries cause a lot of pain and long term troubles for the affected patients. The well established standard procedure of autologous tissue transplantation stabilizes the knee and allows sport activities after 9-12 months. However, harvest of autologous tissue such as patellar tendon or semitendinosus (the most frequently used autograft) weakens other body areas and long term data show an increased rate of arthroses (up to 50\% after 10 years) associated with ACL reconstructions. Based on numerous preclinical data and data from a 12-month sheep study the scale-up as well as regulatory approval process of a novel textile engineered silk implant as ACL graft have been initiated. It is planned to enter a clinical trial and strive for regulatory approval as a medical class 3 implant. The sheep data (1) have revealed an approximately 50\% degradation of the purified medical silk, which acts as scaffold for the regrowth of a new endogenous ligament. The formation of oriented collagenous tissue fibers including vascularization proves a ligament tissue regeneration for the first time. Scale-up and implementation of a commercial process require a defined set of specifications of commercial silkworm (Bombyx mori) silk, a biological raw material sourced from the textile industry as well as adequate analytical methods to characterize the depletion of sericin in the course of the production process. Based on first full scale samples, the defined biocompatibility program has to be executed, in the EU following the ISO requirements of the notified bodies, in the USA determined by the FDA. Upon submission of the full technical documentation as well as the biocompati-bility data, approval of a clinical trial can be achieved in order to demonstrate the clinical efficacy of the silk based ACL graft compared to the gold standard method in two different randomized groups. As primary endpoint the knee stability will be tested by an apparatus supported Lachmann test. In this study, besides the clinical benefit the patient safety is an important goal. The results of this study will be used for achievement of regulatory approval. References: 1) Teuschl A, Heimel P, N{\"u}rnberger S, van Griensven M, Redl H, Nau T. Am. J. Sports Med. 2016;44:1547-57. 2) Teuschl AH, van Griensven M, Redl H. Tissue Eng. Part C Methods. 2014;20:431-9.}, subject = {Biomaterial}, language = {en} } @misc{WilfingFruehwirthLehner, author = {Wilfing, Julia and Fr{\"u}hwirth, Clemens and Lehner, Benjamin}, title = {Feldmessungen der Gleit- und Haftreibungskoeffizienten von Skitourenfellen}, subject = {Skiing}, language = {de} } @article{HackethalMuehlederHoferetal., author = {Hackethal, Johannes and M{\"u}hleder, Severin and Hofer, Alexandra and Schneider, Karl Heinrich and Pr{\"u}ller, Johanna and Hennerbichler, Simone and Redl, Heinz and Teuschl, Andreas}, title = {An Effective Method of Atelocollagen Type 1/3 Isolation from Human Placenta and Its In Vitro Characterization in Two-Dimensional and Three-Dimensional Cell Culture Applications}, series = {Tissue Eng Part C Methods}, volume = {23}, journal = {Tissue Eng Part C Methods}, number = {5}, pages = {274 -- 285}, subject = {Placenta}, language = {en} } @inproceedings{FuchsWeihsSzwarcetal., author = {Fuchs, Christiane and Weihs, Anna and Szwarc, Dorota and Mittermayr, Rainer and R{\"u}nzler, Dominik and Teuschl, Andreas}, title = {Shock wave treatment of muscle (stem) cells - a new implementation for regeneration}, series = {Proceedings of the 20th International Congress of the ISMST}, booktitle = {Proceedings of the 20th International Congress of the ISMST}, subject = {Shockwave treatment}, language = {en} } @article{BerkovitchCohenPeledetal., author = {Berkovitch, Yulia and Cohen, Talia and Peled, Eli and Schmidhammer, Robert and Hildner, Florian and Teuschl, Andreas and Wolbank, Susanne and Yelin, Dvir and Redl, Heinz and Seliktar, Dror}, title = {Hydrogel Composition and Laser Micro-Patterning to Regulate Sciatic Nerve Regeneration}, series = {Journal of Tissue Engineering and Regenerative Medicine}, volume = {12}, journal = {Journal of Tissue Engineering and Regenerative Medicine}, number = {4}, subject = {Micro-Patterning}, language = {en} } @misc{FuchsWeihsSzwarcetal., author = {Fuchs, Christiane and Weihs, Anna and Szwarc, Dorota and Mittermayr, Rainer and R{\"u}nzler, Dominik and Teuschl, Andreas}, title = {Shock wave treatment of muscle (stem) cells - a new implementation for regeneration}, subject = {Shockwave treatment}, language = {en} } @misc{TeuschlWeihsFuchsetal., author = {Teuschl, Andreas and Weihs, Anna and Fuchs, Christiane and Monforte Vila, Xavier}, title = {Silk as a versatile biomaterial for musculoskeletal tissue engineering}, subject = {Silk}, language = {en} } @misc{SzwarcFuchsWeihsetal., author = {Szwarc, Dorota and Fuchs, Christiane and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Molecular mechanisms underlying the potential of shock wave treatment for cardiac therapy}, subject = {Shockwave treatment}, language = {en} } @misc{SzwarcFuchsPurtscheretal., author = {Szwarc, Dorota and Fuchs, Christiane and Purtscher, Michaela and R{\"u}nzler, Dominik}, title = {Elucidating the molecular mechanisms underlying cardiac shock wave therapy}, subject = {Shockwave treatment}, language = {en} } @misc{SaboEckelt, author = {Sabo, Anton and Eckelt, Markus}, title = {Running Shoes - Possible Correlations of Biomechanical and Material Tests}, subject = {Shoes}, language = {en} } @misc{Eckelt, author = {Eckelt, Markus}, title = {Customizing Shoe Insoles through CAD-FEM Modelling}, subject = {Customized Equipment}, language = {en} } @article{BernhardFergusonRiederetal., author = {Bernhard, Jonathan and Ferguson, James and Rieder, Bernhard and Heimel, Patrick and Nau, Thomas and Tangl, Stefan and Redl, Heinz and Vunjak-Novakovic, Gordana}, title = {Tissue-engineered hypertrophic chondrocyte grafts enhanced long bone repair biomaterials}, series = {Biomaterials}, journal = {Biomaterials}, number = {139}, pages = {202 -- 212}, subject = {Grafting}, language = {en} } @misc{KotzianRiessDavidetal., author = {Kotzian, Stefan and Riess, Bernhard and David, Veronika and Haider, Sandra and Spatt, Josef}, title = {Virtual Reality Training in der neurologischen Rehabilitation - Eine Praktikabilit{\"a}tsstudie zu einer Microsoft Kinect-Anwendung}, subject = {Neurology}, language = {de} } @misc{MenschikMallyGruberetal., author = {Menschik, Alfred and Mally, Franziska and Gruber, Martin and Sabo, Anton}, title = {EMG-Messungen am Unterwasserlaufband}, subject = {Electromyography}, language = {de} } @misc{Bayer, author = {Bayer, Natascha}, title = {Analysing the Impact of a Misaligned Toric Intraocular Lens on Wave Front Aberrations}, subject = {Mechanical Eye}, language = {en} } @misc{Ruenzler, author = {R{\"u}nzler, Dominik}, title = {Alternatives to Animal Experiment Models: Tracking Zebrafish Larvae and Daphnia}, subject = {Animal Experiments}, language = {en} } @misc{Eckelt, author = {Eckelt, Markus}, title = {Evaluating the Interaction Between Rim and Brake Pad on a Test Bench}, subject = {Brake}, language = {en} } @misc{Fuchs, author = {Fuchs, Christiane}, title = {The importance of mechanotransduction in myogenesis}, subject = {Mechanotransduction}, language = {en} } @article{SchneiderLehmannvanOschetal., author = {Schneider, Cornelia and Lehmann, Johannes and van Osch, Gerjo and Hildner, Florian and Teuschl, Andreas and Monforte Vila, Xavier and Miosga, David and Heimel, Patrick and Priglinger, Eleni and Redl, Heinz and Wolbank, Susanne and N{\"u}rnberger, Sylvia}, title = {Systematic Comparison of Protocols for the Preparation of Human Articular Cartilage for Use as Scaffold Material in Cartilage Tissue Engineering}, series = {Tissue Eng Part C Methods}, volume = {22}, journal = {Tissue Eng Part C Methods}, number = {12}, subject = {Cartilage}, language = {en} } @inproceedings{MaleinerHeherTeuschletal., author = {Maleiner, Babette and Heher, Philipp and Teuschl, Andreas and Redl, Heinz and R{\"u}nzler, Dominik and Fuchs, Christiane}, title = {Generation of aligned skeletal muscle-like tissue based on the application of strain to a 3D fibrin scaffold}, series = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, booktitle = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, subject = {Tissue Generation}, language = {en} } @misc{SzwarcFuchsWeihsetal., author = {Szwarc, Dorota and Fuchs, Christiane and Weihs, Anna and Monforte Vila, Xavier and Hanetseder, Dominik and Teuschl, Andreas and R{\"u}nzler, Dominik}, title = {The effect of shock waves on in vitro cartilage development in silk scaffolds}, subject = {Shockwave treatment}, language = {en} } @misc{MaleinerHeherTeuschletal., author = {Maleiner, Babette and Heher, Philipp and Teuschl, Andreas and Redl, Heinz and R{\"u}nzler, Dominik and Fuchs, Christiane}, title = {Generation of aligned skeletal muscle-like tissue based on the application of strain to a 3D fibrin scaffold}, subject = {Tissue Generation}, language = {en} } @misc{TeuschlFuchsWeihsetal., author = {Teuschl, Andreas and Fuchs, Christiane and Weihs, Anna and Heimel, Patrick and R{\"u}nzler, Dominik and Redl, Heinz and Nau, Thomas}, title = {The Silk Road from Textiles to Novel Medical Implants}, subject = {Silk}, language = {en} } @misc{TeuschlHeimelNuernbergeretal., author = {Teuschl, Andreas and Heimel, Patrick and N{\"u}rnberger, Sylvia and Redl, Heinz and Nau, Thomas}, title = {ACL Regeneration using a novel silk fiber based scaffold - Histological Results of a Large Animal Study}, subject = {Tissue Regeneration}, language = {en} } @misc{Teuschl, author = {Teuschl, Andreas}, title = {Silk Processing - from Gels to ACL Replacement}, subject = {Silk}, language = {en} } @inproceedings{FuchsSzwarcWeihsetal., author = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Shock wave treatment of 3D cardiac model systems activates ERK 1/2 signaling pathway and influences cardiomyogenesis}, series = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, booktitle = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, subject = {Shockwave treatment}, language = {en} } @inproceedings{FuchsSzwarcWeihsetal., author = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Shock wave treatment of 3D cardiac model systems activates ERK 1/2 signaling pathway and influences cardiomyogenesis}, series = {Proceedings of LBG Meeting for Health Sciences 2016}, booktitle = {Proceedings of LBG Meeting for Health Sciences 2016}, subject = {Shockwave treatment}, language = {en} } @misc{FuchsSzwarcWeihsetal., author = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Shock wave treatment of 3D cardiac model systems activates ERK 1/2 signaling pathway and influences cardiomyogenesis}, subject = {Shockwave treatment}, language = {en} } @inproceedings{FuchsSzwarcWeihsetal., author = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Shock wave treatment positively influences cardiomyogenesis in an energy-dependent manner}, series = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, booktitle = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, subject = {Shockwave treatment}, language = {en} } @misc{Weihs, author = {Weihs, Anna}, title = {Shock wave treatment for in vitro tissue engineering applications}, subject = {Shockwave treatment}, language = {en} } @inproceedings{BasoliChaudryCrucianietal., author = {Basoli, Valentina and Chaudry, Sidrah and Cruciani, Sara and Fuchs, Christiane and Rieger, Sabine and Dungel, Peter and Wolbank, Susanne and Ventura, Carlo and Grillari-Voglauer, Regina and Redl, Heinz and Maioli, Margherita}, title = {Epigenetic and molecular behavious of stem cells exposed to biophysical stimuli: new insights in regenerative medicine}, series = {Proceedings des Seminars zum 40. Jahresjubil{\"a}um der {\"O}sterreichischen Gesellschaft f{\"u}r Chirurgische Forschung}, booktitle = {Proceedings des Seminars zum 40. Jahresjubil{\"a}um der {\"O}sterreichischen Gesellschaft f{\"u}r Chirurgische Forschung}, subject = {Stem Cells}, language = {en} } @misc{BasoliChaudryCrucianietal., author = {Basoli, Valentina and Chaudry, Sidrah and Cruciani, Gabriele and Fuchs, Christiane and Rieger, Sabine and Dungel, Peter and Wolbank, Susanne and Ventura, Carlo and Grillari-Voglauer, Regina and Redl, Heinz and Maioli, Margherita}, title = {Epigenetic and molecular behavious of stem cells exposed to biophysical stimuli: new insights in regenerative medicine}, subject = {Stem Cells}, language = {en} } @misc{HofstaetterBreyerKafkaetal., author = {Hofst{\"a}tter, Otto and Breyer, Peter and Kafka, Patricia and Sabo, Anton}, title = {Development of a prototype for the simulation of human sway to make standardized and reproducible measurements of force and pressure sensors}, subject = {Simulation}, language = {en} } @misc{HoettingerMallySabo, author = {H{\"o}ttinger, Hannes and Mally, Franziska and Sabo, Anton}, title = {Activity recognition in surfing - a comparative study between hidden markov model and support vector machine}, subject = {Activity}, language = {de} } @inproceedings{Drauschke, author = {Drauschke, Andreas}, title = {Comparison of Numerical Eye Models and its Representation within a Mechanical Eye Model}, series = {IFAC-Papers Online}, booktitle = {IFAC-Papers Online}, pages = {133 -- 138}, subject = {Mechanical Eye}, language = {en} } @misc{Drauschke, author = {Drauschke, Andreas}, title = {Comparison of Numerical Eye Models and its Representation within a Mechanical Eye Model}, subject = {Mechanical Eye}, language = {en} } @misc{Weihs, author = {Weihs, Anna}, title = {Shock wave treatment for in vitro tissue engineering applications}, subject = {Shockwave treatment}, language = {en} } @misc{Weihs, author = {Weihs, Anna}, title = {Mechanotransduction in shock wave treatment}, subject = {Shockwave treatment}, language = {en} } @misc{MandtPichlerMelchioretal., author = {Mandt, Denise and Pichler, Verena and Melchior, Sophie and R{\"u}nzler, Dominik}, title = {Establishment of 2D and 3D cell culture assays using RT-gillW1 cells}, subject = {Cell Culture}, language = {en} } @misc{OettlMallySabo, author = {{\"O}ttl, Georg and Mally, Franziska and Sabo, Anton}, title = {The influence of low-friction quickdraws on impact forces in climbing falls}, subject = {Climbing}, language = {en} } @misc{SalzerRuenzler, author = {Salzer, Elias and R{\"u}nzler, Dominik}, title = {Acute Immobilization Test with Daphnia magna - A Refined Methodology for the Detection of Immobilization}, subject = {Immobilization}, language = {en} } @misc{Bayer, author = {Bayer, Natascha}, title = {Analysis of Customized Ocular Data and Wave Front Aberrations Concerning their Deviations from Generic Eye Models}, subject = {Mechanical Eye}, language = {en} } @misc{SalzerRuenzler, author = {Salzer, Elias and R{\"u}nzler, Dominik}, title = {Live or dead is not enough: a large-scale mobility assay with Daphnia magna}, subject = {Mobility Assay}, language = {en} } @misc{Fuchs, author = {Fuchs, Christiane}, title = {A mechanical stimulation strategy for engineering skeletal muscle-like tissue on a strained fibrin scaffold}, subject = {Muscle Tissue}, language = {en} } @misc{Frohner, author = {Frohner, Matthias}, title = {How to Design Mobile Applications for Security, Safety and Usability}, subject = {Electronic Health Records}, language = {de} } @misc{Fuchs, author = {Fuchs, Christiane}, title = {The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent}, subject = {In Vitro}, language = {en} } @misc{DavidAigner, author = {David, Veronika and Aigner, Benjamin}, title = {AsTeRICS Framework}, subject = {Cross-Cultural Education}, language = {en} } @misc{Fuchs, author = {Fuchs, Christiane}, title = {Mechanotransduction - bioreactors}, subject = {Bioreactors}, language = {en} } @article{HeherMaleinerPruelleretal., author = {Heher, Philipp and Maleiner, Babette and Pr{\"u}ller, Johanna and Teuschl, Andreas and Kollmitzer, Josef and Monforte Vila, Xavier and Wolbank, Susanne and Redl, Heinz and R{\"u}nzler, Dominik and Fuchs, Christiane}, title = {A novel bioreactor for the generation of highly aligned 3D skeletal muscle-like constructs through orientation of fibrin via application of static strain}, series = {Acta Biomaterialia}, journal = {Acta Biomaterialia}, subject = {Bioreactor}, language = {en} } @article{TeuschlSchuhHalbweisetal., author = {Teuschl, Andreas and Schuh, Christina and Halbweis, Robert and Pajer, Krisztian and Marton, Gabor and Hopf, Rudolf and Mosia, Shorena and R{\"u}nzler, Dominik and Redl, Heinz and Nogradi, Antal and Hausner, Thomas}, title = {A new preparation method for anisotropic silk fibroin nerve guidance conduits and its evaluation in vitro and in a rat sciatic nerve defect model}, series = {Tissue Engineering Part C: Methods}, journal = {Tissue Engineering Part C: Methods}, subject = {Fibrin}, language = {en} } @misc{TeuschlSchuhHalbweisetal., author = {Teuschl, Andreas and Schuh, Christina and Halbweis, Robert and Marton, G{\´a}bor and Pajer, Kriszti{\´a}n and Hopf, Rudolf and Mosia, Shorena and R{\"u}nzler, Dominik and N{\´o}gr{\´a}di, Antal and Hausner, Thomas and Redl, Heinz}, title = {Silk fibroin for peripheral nerve regeneration: a novel preparation method improved mechanical characteristics and supports regeneration in rat sciatic nerves}, subject = {Fibroin}, language = {en} } @misc{FuchsWeihsTeuschletal., author = {Fuchs, Christiane and Weihs, Anna and Teuschl, Andreas and Hartinger, Joachim and Slezak, Paul and Mittermayr, Rainer and Redl, Heinz and Junger, Wolfgang and Sitte, Harald and R{\"u}nzler, Dominik}, title = {Shockwave Treatment Enhances Proliferation and Improves Wound Healing via Purinergic Signaling Linked ERK 1/2 Pathways}, subject = {Shockwave treatment}, language = {en} } @misc{FuchsWeihsTeuschletal., author = {Fuchs, Christiane and Weihs, Anna and Teuschl, Andreas and Hartinger, Joachim and Slezak, Paul and Mittermayr, Rainer and Redl, Heinz and Junger, Wolfgang and Sitte, Harald and R{\"u}nzler, Dominik}, title = {Shockwave Treatment Augments Proliferation and Improves Wound Healing via Purinergic Signaling Linked ERK 1/2 Pathways}, subject = {Shockwave treatment}, language = {en} } @misc{HeherFuchsPruelleretal., author = {Heher, Philipp and Fuchs, Christiane and Pr{\"u}ller, Johanna and Babette, Maleiner and R{\"u}nzler, Dominik and Redl, Heinz}, title = {A novel bioreactor for engineering skeletal muscle-like tissue in a strained fibrin scaffold}, subject = {Bioreactor}, language = {en} } @article{GuillaumeParkMonforteVilaetal., author = {Guillaume, Olivier and Park, Jaesung and Monforte Vila, Xavier and Gruber-Blum, Simone and Redl, Heinz and Petter-Puchner, Akexander and Teuschl, Andreas}, title = {Fabrication of silk mesh with enhanced cytocompatibility: preliminary in vitro investigation toward cell-based therapy for hernia repair}, series = {Journal of Materials Science: Materials in Medicine}, journal = {Journal of Materials Science: Materials in Medicine}, subject = {Cytocompatibility}, language = {en} } @misc{WeihsFuchsTeuschletal., author = {Weihs, Anna and Fuchs, Christiane and Teuschl, Andreas and Hartinger, Joachim and Slezak, Paul and Mittermayr, Rainer and Redl, Heinz and Junger, Wolfgang and Sitte, Harald and R{\"u}nzler, Dominik}, title = {Shockwave treatment activates Erk1/2 pathways predominantly via P2Y receptor involvement}, subject = {Shockwave}, language = {en} } @article{TeuschlHeimelNuernbergeretal., author = {Teuschl, Andreas and Heimel, Patrick and N{\"u}rnberger, Sylvia and van Griensven, Martijn and Redl, Heinz and Nau, Thomas}, title = {A Novel Silk Fiber-Based Scaffold for Regeneration of the Anterior Cruciate Ligament: Histological Results From a Study in Sheep.}, series = {The American Journal of Sports Medicine}, journal = {The American Journal of Sports Medicine}, subject = {Ligament}, language = {en} } @misc{TeuschlFuchsFeichtingeretal., author = {Teuschl, Andreas and Fuchs, Christiane and Feichtinger, Georg and Heher, Philipp and Heimel, Patrick and Schuh, Christina and N{\"u}rnberger, Sylvia and Nau, Thomas and R{\"u}nzler, Dominik and Redl, Heinz}, title = {Fibrin or Fibroin - Not only the "o" Makes the Difference}, subject = {Fibrin}, language = {en} } @article{TeuschlBalmayorRedletal., author = {Teuschl, Andreas and Balmayor, Elizabeth and Redl, Heinz and van Griensven, Martijn and Dungel, Peter}, title = {Phototherapy With LED Light Modulates Healing Processes in an In Vitro Scratch Wound-Model Using 3 Different Cell Types}, series = {Dermatologic Surgery}, volume = {41}, journal = {Dermatologic Surgery}, number = {2}, pages = {261 -- 268}, subject = {Phototherapy}, language = {en} } @article{SchuhHercherStaineretal., author = {Schuh, Christina and Hercher, David and Stainer, Michaela and Hopf, Rudolf and Teuschl, Andreas and Schmidhammer, Robert and Redl, Heinz}, title = {Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture}, series = {Cytotherapy}, journal = {Cytotherapy}, subject = {Extracorporeal shockwave}, language = {en} } @misc{TeuschlNuernbergerHeimeletal., author = {Teuschl, Andreas and N{\"u}rnberger, Sylvia and Heimel, Patrick and Redl, Heinz and Nau, Thomas}, title = {Regeneration of the Anterior Cruciate Ligament Using a Silk-Fiber Based Scaffold - Histological Results}, subject = {Tissue Regeneration}, language = {en} } @article{NauRedlTeuschl, author = {Nau, Thomas and Redl, Heinz and Teuschl, Andreas}, title = {Comment on: In Vivo Evaluation of Electrospun Polycaprolactone Graft for Anterior Cruciate Ligament Engineering}, series = {Tissue Engineering Part A}, journal = {Tissue Engineering Part A}, subject = {Grafting}, language = {en} } @article{GauillaumeTeuschlGruberBlum, author = {Gauillaume, Oliver and Teuschl, Andreas and Gruber-Blum, Simone}, title = {Emerging Trends in Abdominal Wall Reinforcement: Bringing Bio-Functionality to Meshes}, series = {Advanced Healthcare Materials}, journal = {Advanced Healthcare Materials}, subject = {Abdominal Wall Reinforcement}, language = {en} } @article{NauTeuschl, author = {Nau, Thomas and Teuschl, Andreas}, title = {Regeneration of the anterior cruciate ligament: Current strategies in tissue engineering}, series = {World Journal of Orthopedics}, volume = {6}, journal = {World Journal of Orthopedics}, number = {1}, subject = {Ligament}, language = {en} } @phdthesis{Weihs, author = {Weihs, Anna}, title = {Elucidation of extracorporeal shock wave treatment triggered intracellular processes}, school = {Fachhochschule Technikum Wien}, abstract = {Die Wirkung von Stoßwellen auf den menschlichen K{\"o}rper ist bereits seit Jahrzehnten bekannt. Ihr zerst{\"o}rerisches Potential wird seit den 1980-ern zur Behandlung und Desintegration von Nierensteinen angewendet, wo die Stoßwellentherapie heutzutage die Standardbehandlung darstellt. Der erste unerwartete Effekt der Therapie - die Verdichtung des Beckenkammes - wurde schon damals bei Folgeuntersuchungen von Patienten mit Nierensteinen festgestellt. Die Beobachtung, dass Stoßwellen Effekte auf Knochen hervorrufen, ebnete den Weg f{\"u}r die Anwendung der Stoßwellentherapie in Bereichen abseits der Urologie. Mittlerweile wird die Stoßwellentherapie nicht nur zur Behandlung von Knochenbruchheilungsst{\"o}rungen und Tendinopathien, sondern auch bei Weichteilwundheilungsst{\"o}rungen eingesetzt. Trotz der vielf{\"a}ltigen Anwendungsgebiete ist der zugrunde liegende Wirkungsmechanismus des positiven Effekts der Stoßwellentherapie bis heute noch nicht vollst{\"a}ndig aufgekl{\"a}rt. Die Aktivierung von mechanotransduktiven Signalwegen wurde bereits teilweise in vitro und in vivo gezeigt, jedoch meist bei kn{\"o}chernen Indikationen. Doch auch f{\"u}r die Anwendung der Stoßwellentherapie in der (verz{\"o}gerten) Wundheilung ist die Aufkl{\"a}rung des Wirkungsmechanismus essentiell. Erst dadurch k{\"o}nnte diese nicht- invasive, effiziente und großteils Nebenwirkungs-freie Therapieform auch in diesem Bereich als m{\"o}gliche Standardtherapieform genutzt werden. In dieser Dissertation wurde zuerst ein Set-up zur in vitro Stoßwellenanwendung optimiert. Mithilfe eines Molek{\"u}l-Aufnahme Assays wurden die technischen Parameter f{\"u}r die in vitro Stoßwellenbehandlung festgelegt. Mit diesem in vitro Aufbau sollten daraufhin jene intrazellul{\"a}ren Mechanismen identifiziert werden, die von der Stoßwelle beeinflusst werden. In einem in vivo Modell sollte schlussendlich die Rolle dieser Mechanismen am wundheilungsf{\"o}rdernden Effekt der Stoßwelle gekl{\"a}rt werden. Um m{\"o}glichst universelle Effekte der Stoßwelle auf intrazellul{\"a}re Signalwege zu untersuchen, wurden verschiedenste Zelllinien verwendet. Diese beinhalteten die humane U937 Monozyten Zelllinie, humane Jurkat T-Zellen, die humane MG63 Osteosarcoma Zelllinie, die murine C3H10T1/2 mesenchymale Progenitor Zelllinie sowie prim{\"a}re humane mononukle{\"a}re Zellen des peripheren Blutes. Die in den proliferativen Effekt der Stowellentherapie involvierte Signalkaskade konnte darauffolgend erstmals sowohl in murinen C3H10T1/2 Zellen als auch in humanen Fettstammzellen (adipose tissue-derived stem cells) und in humanen Jurkat T-Zellen detailliert beschrieben werden. Außerdem wurde ATP als entscheidendes Signalmolek{\"u}l identifiziert, welches nach Freisetzung durch Stoßwellenbehandlung mittels purinergem Signaling die Erk1/2 Signalkaskade aktiviert. F{\"u}r die dadurch gesteigerte Proliferation in stoßwellenbehandelten Zellen ist die Erk1/2 Aktivierung essentiell. In einem in vivo Model f{\"u}r gest{\"o}rte Wundheilung in der Ratte wurde die Hypothese zur entscheidenden Rolle des Erk1/2 Signalweges im wundheilungsf{\"o}rdernden Effekt der Stoßwelle best{\"a}tigt. In dieser Dissertation wurde gezeigt, dass die durch purinerges Signaling aktivierte Erk1/2 Signalkaskade eine entscheidende Rolle in der durch Stoßwellentherapie beschleunigten Zellproliferation in vitro und Wundheilung in vivo {\"u}bernimmt. Das damit erweiterte Verst{\"a}ndnis der Wirkungsmechanismen der Stoßwellentherapie kann zur Weiterentwicklung dieser Behandlungsform als zuk{\"u}nftige Standardtherapie bei Wundheilungsst{\"o}rungen, wie z.B. f{\"u}r diabetische oder chronische Wunden, beitragen.}, subject = {Healing}, language = {en} } @inproceedings{TkachenkoBrilDavidSchereretal., author = {Tkachenko Bril, Andres Igor and David, Veronika and Scherer, Matthias and Jagos, Harald and Kafka, Patricia and Sabo, Anton}, title = {Development of a Wearable Live-feedback System to Support Partial Weight-bearing While Recovering From Lower Extremity Injuries}, series = {Proceedings of the 11th Conference of the International Sports Engineering Association (ISEA) 2016}, booktitle = {Proceedings of the 11th Conference of the International Sports Engineering Association (ISEA) 2016}, subject = {Injuries}, language = {en} } @misc{TkachenkoBrilDavidSchereretal., author = {Tkachenko Bril, Andres Igor and David, Veronika and 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