@article{Himmelstoss, author = {Himmelstoss, Felix}, title = {Design of State-Space Controllers with the Help of Signal Flow Graphs Shown for a Buck Converter}, series = {WSEAS Transactions on Power Systems, Volume 21, 2022, pp. 421-429}, volume = {Volume 21}, journal = {WSEAS Transactions on Power Systems, Volume 21, 2022, pp. 421-429}, doi = {10.37394/23202.2022.21.46}, pages = {421 -- 429}, subject = {DC/DC converter}, language = {en} } @article{HimmelstossVotzi, author = {Himmelstoss, Felix and Votzi, Helmut}, title = {Simple Chargers for a Small DC Micro-Grid for a Home Emergency Power System}, series = {Electricity}, volume = {4}, journal = {Electricity}, number = {3}, doi = {https://doi.org/10.3390/electricity4030013}, pages = {216 -- 234}, subject = {micro-grid}, language = {en} } @article{Himmelstoss, author = {Himmelstoss, Felix}, title = {Quasi Resonant Zero Current Switching Modified Boost Converter (QRZCSMBC)}, series = {WSEAS Transactions on Power Systems}, volume = {Volume 22}, journal = {WSEAS Transactions on Power Systems}, doi = {10.37394/23201.2023.22.8}, pages = {55 -- 62}, subject = {DC/DC converter}, language = {en} } @article{Himmelstoss, author = {Himmelstoss, Felix}, title = {Third order converters with current output for driving LEDs}, series = {WSEAS Transactions on Power Systems}, volume = {Volume 17}, journal = {WSEAS Transactions on Power Systems}, doi = {10.37394/232016.2022.17.40}, pages = {402 -- 409}, subject = {DC/DC converters}, language = {en} } @article{MarcKnappNateqietal., author = {Marc, Zobel and Knapp, Bernhard and Nateqi, Jama and Martin, Alistair}, title = {Correlating global trends in COVID-19 cases with online symptom checker self-assessments}, series = {PLOS ONE}, volume = {18}, journal = {PLOS ONE}, number = {2}, doi = {https://doi.org/10.1371/journal.pone.0281709}, pages = {10}, abstract = {Background Online symptom checkers are digital health solutions that provide a differential diagnosis based on a user's symptoms. During the coronavirus disease 2019 (COVID-19) pandemic, symptom checkers have become increasingly important due to physical distance constraints and reduced access to in-person medical consultations. Furthermore, various symptom checkers specialised in the assessment of COVID-19 infection have been produced. Objectives Assess the correlation between COVID-19 risk assessments from an online symptom checker and current trends in COVID-19 infections. Analyse whether those correlations are reflective of various country-wise quality of life measures. Lastly, determine whether the trends found in symptom checker assessments predict or lag relative to those of the COVID-19 infections. Materials and methods In this study, we compile the outcomes of COVID-19 risk assessments provided by the symptom checker Symptoma (www.symptoma.com) in 18 countries with suitably large user bases. We analyse this dataset's spatial and temporal features compared to the number of newly confirmed COVID-19 cases published by the respective countries. Results We find an average correlation of 0.342 between the number of Symptoma users assessed to have a high risk of a COVID-19 infection and the official COVID-19 infection numbers. Further, we show a significant relationship between that correlation and the self-reported health of a country. Lastly, we find that the symptom checker is, on average, ahead (median +3 days) of the official infection numbers for most countries. Conclusion We show that online symptom checkers can capture the national-level trends in coronavirus infections. As such, they provide a valuable and unique information source in policymaking against pandemics, unrestricted by conventional resources.}, subject = {Online symptom checkers}, language = {en} } @article{WalaFelleitnerGollWechselberger, author = {Wala, Thomas and Felleitner-Goll, Katharina and Wechselberger, Harald}, title = {Stellhebel beim Aufbau von Corporate Start-ups. Dargestellt am Start-Up-Projekt „Hallo Sonne"}, series = {CFO aktuell}, journal = {CFO aktuell}, number = {7}, pages = {130 -- 134}, subject = {Start-ups}, language = {de} } @article{WalaFelleitnerGoll, author = {Wala, Thomas and Felleitner-Goll, Katharina}, title = {Digitalisierung in der Weiterbildung. Wie man mit eigenen Online-Kursen ein passives Zusatzeinkommen generieren kann.}, series = {ASoK}, journal = {ASoK}, number = {5}, pages = {189 -- 191}, subject = {Weiterbildung}, language = {de} } @article{WalaFelleitnerGoll, author = {Wala, Thomas and Felleitner-Goll, Katharina}, title = {Technologiemanagement}, series = {WISU}, journal = {WISU}, number = {4}, pages = {349 -- 350}, subject = {Technologiemanagement}, language = {de} } @article{KierspelKadekBarranetal., author = {Kierspel, Thomas and Kadek, Alan and Barran, Perdita and Bellina, Bruno and Bijedic, Adi and Brodmerkel, Maxim N. and Commandeur, Jan and Caleman, Carl and Damjanovic, Tomislav and Dawod, Ibrahim and De Santis, Emiliano and Lekkas, Alexandros and Lorenzen, Kristina and L{\´o}pez Morillo, Luis and Mandl, Thomas and Marklund, Erik G. and Papanastasiou, Dimitris and Ramakers, Lennart A. I. and Schweikhard, Lutz and Simke, Florian and Sinelnikova, Anna and Smyrnakis, Athanasios and Timneanu, Nicusor and Uetrecht, Charlotte}, title = {Coherent diffractive imaging of proteins and viral capsids: simulating MS SPIDOC}, series = {Analytical and Bioanalytical Chemistry}, volume = {2023}, journal = {Analytical and Bioanalytical Chemistry}, number = {415}, doi = {https://doi.org/10.1007/s00216-023-04658-y}, pages = {4209 -- 4220}, abstract = {MS SPIDOC is a novel sample delivery system designed for single (isolated) particle imaging at X-ray Free-Electron Lasers that is adaptable towards most large-scale facility beamlines. Biological samples can range from small proteins to MDa particles. Following nano-electrospray ionization, ionic samples can be m/z-filtered and structurally separated before being oriented at the interaction zone. Here, we present the simulation package developed alongside this prototype. The first part describes how the front-to-end ion trajectory simulations have been conducted. Highlighted is a quadrant lens; a simple but efficient device that steers the ion beam within the vicinity of the strong DC orientation field in the interaction zone to ensure spatial overlap with the X-rays. The second part focuses on protein orientation and discusses its potential with respect to diffractive imaging methods. Last, coherent diffractive imaging of prototypical T = 1 and T = 3 norovirus capsids is shown. We use realistic experimental parameters from the SPB/SFX instrument at the European XFEL to demonstrate that low- resolution diffractive imaging data (q < 0.3 nm -1 ) can be collected with only a few X-ray pulses. Such low-resolution data are sufficient to distinguish between both symmetries of the capsids, allowing to probe low abundant species in a beam if MS SPIDOC is used as sample delivery.}, subject = {SPI}, language = {en} } @article{HendersonSlingersPedrottietal., author = {Henderson, Ben and Slingers, Gitte and Pedrotti, Michele and Pugliese, Giovanni and Malaskova, Michaela and Bryant, Luke and Lomonaco, Tommaso and Ghimenti, Silvia and Moreno, Sergi and Cordell, Rebecca and Harren, Frans J M and Schubert, Jochen and Mayhew, Chris A and Wilde, Michael and Di Francesco, Fabio and Koppen, Gudrun and Beauchamp, Jonathan D and Cristescu, Simona M}, title = {The peppermint breath test benchmark for PTR-MS and SIFT-MS}, series = {Journal of Breath Research}, journal = {Journal of Breath Research}, number = {15}, doi = {https://doi.org/10.1088/1752-7163/ac1fcf}, pages = {Artikelnr. 046005}, abstract = {A major challenge for breath research is the lack of standardization in sampling and analysis. To address this, a test that utilizes a standardized intervention and a defined study protocol has been proposed to explore disparities in breath research across different analytical platforms and to provide benchmark values for comparison. Specifically, the Peppermint Experiment involves the targeted analysis in exhaled breath of volatile constituents of peppermint oil after ingestion of the encapsulated oil. Data from the Peppermint Experiment performed by proton transfer reaction mass spectrometry (PTR-MS) and selected ion flow tube mass spectrometry (SIFT-MS) are presented and discussed herein, including the product ions associated with the key peppermint volatiles, namely limonene, α- and β-pinene, 1,8-cineole, menthol, menthone and menthofuran. The breath washout profiles of these compounds from 65 individuals were collected, comprising datasets from five PTR-MS and two SIFT-MS instruments. The washout profiles of these volatiles were evaluated by comparing the log-fold change over time of the product ion intensities associated with each volatile. Benchmark values were calculated from the lower 95\% confidence interval of the linear time-to-washout regression analysis for all datasets combined. Benchmark washout values from PTR-MS analysis were 353 min for the sum of monoterpenes and 1,8-cineole (identical product ions), 173 min for menthol, 330 min for menthofuran, and 218 min for menthone; from SIFT-MS analysis values were 228 min for the sum of monoterpenes, 281 min for the sum of monoterpenes and 1,8-cineole, and 370 min for menthone plus 1,8-cineole. Large inter- and intra-dataset variations were observed, whereby the latter suggests that biological variability plays a key role in how the compounds are absorbed, metabolized and excreted from the body via breath. This variability seems large compared to the influence of sampling and analytical procedures, but further investigations are recommended to clarify the effects of these factors.}, subject = {standardization}, language = {en} } @article{SpadaDemarqueKupka, author = {Spada, Federico and Demarque, Pierre and Kupka, Friedrich}, title = {Stellar evolution models with entropy-calibrated mixing-length parameter: application to red giants}, series = {Mon. Not. Roy. Astron. Soc.}, journal = {Mon. Not. Roy. Astron. Soc.}, doi = {https://doi.org/10.1093/mnras/stab1106}, subject = {solar}, language = {en} } @article{HanetsederLevstekTeuschlWolleretal., author = {Hanetseder, Dominik and Levstek, Tina and Teuschl-Woller, Andreas and Frank, Julia Katharina and Schaedl, Barbara and Redl, Heinz and Marolt Presen, Darja}, title = {Engineering of extracellular matrix from human iPSC-mesenchymal progenitors to enhance osteogenic capacity of human bone marrow stromal cells independent of their age}, series = {Front Bioeng Biotechnol}, volume = {11}, journal = {Front Bioeng Biotechnol}, doi = {https://doi.org/10.3389/fbioe.2023.1214019}, abstract = {Regeneration of bone defects is often limited due to compromised bone tissue physiology. Previous studies suggest that engineered extracellular matrices enhance the regenerative capacity of mesenchymal stromal cells. In this study, we used human-induced pluripotent stem cells, a scalable source of young mesenchymal progenitors (hiPSC-MPs), to generate extracellular matrix (iECM) and test its effects on the osteogenic capacity of human bone-marrow mesenchymal stromal cells (BMSCs). iECM was deposited as a layer on cell culture dishes and into three-dimensional (3D) silk-based spongy scaffolds. After decellularization, iECM maintained inherent structural proteins including collagens, fibronectin and laminin, and contained minimal residual DNA. Young adult and aged BMSCs cultured on the iECM layer in osteogenic medium exhibited a significant increase in proliferation, osteogenic marker expression, and mineralization as compared to tissue culture plastic. With BMSCs from aged donors, matrix mineralization was only detected when cultured on iECM, but not on tissue culture plastic. When cultured in 3D iECM/silk scaffolds, BMSCs exhibited significantly increased osteogenic gene expression levels and bone matrix deposition. iECM layer showed a similar enhancement of aged BMSC proliferation, osteogenic gene expression, and mineralization compared with extracellular matrix layers derived from young adult or aged BMSCs. However, iECM increased osteogenic differentiation and decreased adipocyte formation compared with single protein substrates including collagen and fibronectin. Together, our data suggest that the microenvironment comprised of iECM can enhance the osteogenic activity of BMSCs, providing a bioactive and scalable biomaterial strategy for enhancing bone regeneration in patients with delayed or failed bone healing.}, subject = {aging}, language = {en} } @article{BernhardMaroltPresenLietal., author = {Bernhard, Jonathan C and Marolt Presen, Darja and Li, Ming and Monforte, Xavier and Ferguson, James and Leinfellner, Gabriele and Heimel, Patrick and Betti, Susanne L and Shu, Sharon and Teuschl-Woller, Andreas H and Tangl, Stefan and Redl, Heinz and Vunjak-Novakovic, Gordana}, title = {Effects of Endochondral and Intramembranous Ossification Pathways on Bone Tissue Formation and Vascularization in Human Tissue-Engineered Grafts}, series = {Cells}, volume = {11}, journal = {Cells}, number = {19:3070}, doi = {10.3390/cells11193070}, abstract = {Bone grafts can be engineered by differentiating human mesenchymal stromal cells (MSCs) via the endochondral and intramembranous ossification pathways. We evaluated the effects of each pathway on the properties of engineered bone grafts and their capacity to drive bone regeneration. Bone-marrow-derived MSCs were differentiated on silk scaffolds into either hypertrophic chondrocytes (hyper) or osteoblasts (osteo) over 5 weeks of in vitro cultivation, and were implanted subcutaneously for 12 weeks. The pathways' constructs were evaluated over time with respect to gene expression, composition, histomorphology, microstructure, vascularization and biomechanics. Hypertrophic chondrocytes expressed higher levels of osteogenic genes and deposited significantly more bone mineral and proteins than the osteoblasts. Before implantation, the mineral in the hyper group was less mature than that in the osteo group. Following 12 weeks of implantation, the hyper group had increased mineral density but a similar overall mineral composition compared with the osteo group. The hyper group also displayed significantly more blood vessel infiltration than the osteo group. Both groups contained M2 macrophages, indicating bone regeneration. These data suggest that, similar to the body's repair processes, endochondral pathway might be more advantageous when regenerating large defects, whereas intramembranous ossification could be utilized to guide the tissue formation pattern with a scaffold architecture.}, subject = {bone tissue engineering}, language = {en} } @article{GollmannTepekoeylueGraberHirschetal., author = {Gollmann-Tepek{\"o}yl{\"u}, Can and Graber, Michael and Hirsch, Jakob and Mair, Sophia and Naschberger, Andreas and P{\"o}lzl, Leo and N{\"a}gele, Felix and Kirchmair, Elke and Degenhart, Gerald and Demetz, Egon and Hilbe, Richard and Chen, Hao-Yu and Engert, James C and B{\"o}hm, Anna and Franz, Nadja and Lobenwein, Daniela and Lener, Daniela and Fuchs, Christiane and Weihs, Anna and T{\"o}chterle, Sonja and Vogel, Georg F and Schweiger, Victor and Eder, Jonas and Pietschmann, Peter and Seifert, Markus and Kronenberg, Florian and Coassin, Stefan and Blumer, Michael and Hackl, Hubert and Meyer, Dirk and Feuchtner, Gudrun and Kirchmair, Rudolf and Troppmair, Jakob and Krane, Markus and Weiss, G{\"u}nther and Tsimikas, Sotirios and Thanassoulis, George and Grimm, Michael and Rupp, Bernhard and Huber, Lukas A and Zhang, Shen-Ying and Casanova, Jean-Laurent and Tancevski, Ivan and Holfeld, Johannes}, title = {Toll-Like Receptor 3 Mediates Aortic Stenosis Through a Conserved Mechanism of Calcification}, series = {Circulation}, volume = {147}, journal = {Circulation}, number = {20}, doi = {10.1161/CIRCULATIONAHA.122.063481}, pages = {1518 -- 1533}, subject = {Toll-like receptor 3}, language = {en} } @article{XuGeppLenggeretal., author = {Xu, Yingyang and Gepp, Barbara and Lengger, Nina and Yin, Jia and Breiteneder, Heimo}, title = {Identification of probable pectinesterase as a major allergen of pollen of the Asian white birch (Betula platyphylla) in northern China}, series = {Asian Pac J Allergy Immunol}, journal = {Asian Pac J Allergy Immunol}, doi = {10.12932/AP-100722-1409}, subject = {birch pollen allergy}, language = {en} } @article{RomanelliBielerHeimeletal., author = {Romanelli, Pasquale and Bieler, Lara and Heimel, Patrick and Škokić, Siniša and Jakubecova, Dominika and Kreutzer, Christina and Zaunmair, Pia and Smolčić, Tomislav and Benedetti, Bruno and Rohde, Eva and Gimona, Mario and Hercher, David and Dobrivojević Radmilović, Marina and Couillard-Despres, Sebastien}, title = {Enhancing Functional Recovery Through Intralesional Application of Extracellular Vesicles in a Rat Model of Traumatic Spinal Cord Injury}, series = {Front Cell Neurosci}, volume = {15}, journal = {Front Cell Neurosci}, doi = {10.3389/fncel.2021.795008}, abstract = {Local inflammation plays a pivotal role in the process of secondary damage after spinal cord injury. We recently reported that acute intravenous application of extracellular vesicles (EVs) secreted by human umbilical cord mesenchymal stromal cells dampens the induction of inflammatory processes following traumatic spinal cord injury. However, systemic application of EVs is associated with delayed delivery to the site of injury and the necessity for high doses to reach therapeutic levels locally. To resolve these two constraints, we injected EVs directly at the lesion site acutely after spinal cord injury. We report here that intralesional application of EVs resulted in a more robust improvement of motor recovery, assessed with the BBB score and sub-score, as compared to the intravenous delivery. Moreover, the intralesional application was more potent in reducing inflammation and scarring after spinal cord injury than intravenous administration. Hence, the development of EV-based therapy for spinal cord injury should aim at an early application of vesicles close to the lesion.}, subject = {exosomes}, language = {en} } @article{FeichtingerHeimelTangletal., author = {Feichtinger, Xaver and Heimel, Patrick and Tangl, Stefan and Keibl, Claudia and N{\"u}rnberger, Sylvia and Schanda, Jakob Emanuel and Hercher, David and Kocijan, Roland and Redl, Heinz and Grillari, Johannes and Fialka, Christian and Mittermayr, Rainer}, title = {Improved biomechanics in experimental chronic rotator cuff repair after shockwaves is not reflected by bone microarchitecture}, series = {PLoS One}, volume = {17}, journal = {PLoS One}, number = {1}, doi = {10.1371/journal.pone.0262294}, subject = {chronic rotator cuff repair}, language = {en} } @article{AhlbornKupkaWeissetal., author = {Ahlborn, Felix and Kupka, Friedrich and Weiss, Achim and Flaskamp, Martin}, title = {Stellar evolution models with overshooting based on 3-equation non-local theories: II. Main sequence models of A- and B-type stars}, series = {Astronomy \& Astrophysics}, journal = {Astronomy \& Astrophysics}, number = {Volume 667}, doi = {https://doi.org/10.1051/0004-6361/202243126}, pages = {Article Number A97}, subject = {convection}, language = {en} } @article{KupkaAhlbornWeiss, author = {Kupka, Friedrich and Ahlborn, Felix and Weiss, Achim}, title = {Stellar evolution models with overshooting based on 3-equation non-local theories: I. Physical basics and the computation of the dissipation rate}, series = {Astronomy \& Astrophysics}, journal = {Astronomy \& Astrophysics}, number = {Volume 667}, doi = {https://doi.org/10.1051/0004-6361/202243125}, pages = {Article Number A96}, subject = {convection}, language = {en} } @article{Huber, author = {Huber, Albert}, title = {Quasilocal corrections to Bondi's mass-loss formula and dynamical horizons}, series = {Physical Review D}, volume = {Vol. 108}, journal = {Physical Review D}, number = {issue 8}, doi = {https://doi.org/10.1103/PhysRevD.108.084056}, subject = {Bondi´s mass-loss formula}, language = {en} } @article{MairhoferMaiwoegerRiepletal., author = {Mairhofer, Lukas and Maiw{\"o}ger, Mira and Riepl, Martin and Embacher, Franz and Krizek, Gerd Christian}, title = {Experimente zur Quanteninformation}, series = {plusLucis}, journal = {plusLucis}, number = {2}, pages = {7 -- 7}, subject = {Quanteninformation}, language = {de} } @article{WalaFelleitnerGoll, author = {Wala, Thomas and Felleitner-Goll, Katharina}, title = {Die betriebswirtschaftliche Klausur: Kostenmanagement.}, series = {WISU}, journal = {WISU}, number = {1}, pages = {74 -- 76}, subject = {Kostenmanagement}, language = {de} } @article{WalaFelleitnerGoll, author = {Wala, Thomas and Felleitner-Goll, Katharina}, title = {Die betriebswirtschaftliche Klausur: Controlling}, series = {WISU}, journal = {WISU}, pages = {673 -- 674}, subject = {Controlling}, language = {de} }