@article{MandlMeyerspeerReicheletal., author = {Mandl, Thomas and Meyerspeer, Martin and Reichel, Martin and Kern, Helmut and Hofer, Christian and Mayr, Winfried and Moser, Ewald}, title = {Functional electrical stimulation of long-term denervated, degenerated human skeletal muscle: estimating activation using T2-parameter magnetic resonance imaging methods}, series = {Artif Organs}, journal = {Artif Organs}, number = {32(8)}, pages = {604 -- 608}, subject = {Electrical Stimulation}, language = {en} } @misc{TeuschlFuchs, author = {Teuschl, Andreas and Fuchs, Christiane}, title = {Bioreactors in Musculoskeletal Tissue Engineering}, subject = {Bioreactor}, language = {en} } @misc{HeherTomaschMaleineretal., author = {Heher, Philipp and Tomasch, Janine and Maleiner, Babette and Redl, Heinz and Fuchs, Christiane}, title = {The Importance of Biomechanical Cues for In Vitro Skeletal Myogenesis}, subject = {In Vitro}, language = {en} } @misc{Tomasch, author = {Tomasch, Janine}, title = {Generation of 3D skeletal muscle-like scaffolds via the application of mechanical stimuli}, subject = {Scaffold}, language = {en} } @article{SchuhHeherWeihsetal., author = {Schuh, Christina and Heher, Philipp and Weihs, Anna and Fuchs, Christiane and Gabriel, Christian and Wolbank, Susanne and Mittermayr, Rainer and Redl, Heinz and R{\"u}nzler, Dominik and Teuschl, Andreas}, title = {In vitro extracorporeal shock wave treatment enhances stemness and preserves multipotency of rat and human adipose-derived stem cells}, series = {Journal of Cytotherapy}, journal = {Journal of Cytotherapy}, subject = {Shockwave}, language = {en} } @misc{MandlDohnalStickleretal., author = {Mandl, Thomas and Dohnal, Fahdi and Stickler, Yvonne and Martinek, Johannes and Reichel, Martin and Mayr, Winfried and Rattay, Frank}, title = {FE-Modellierung f{\"u}r Implantate als Alternative zur transkutanen Elektrostimulation des langzeitdenervierten Oberschenkels}, subject = {Implants}, language = {de} } @misc{KornfeindBlahaPeuschletal., author = {Kornfeind, P. and Blaha, A. and Peuschl, M. and Reichel, Martin and Sabo, Anton}, title = {2-Komponentenplattform zur Erfassung der Stemmbrettkr{\"a}fte am Ruderergometer und im Ruderboot}, subject = {Sport}, language = {de} } @misc{KueenburgTeuschl, author = {K{\"u}enburg, Bernhard and Teuschl, Andreas}, title = {Regenerative silk ligament: scale up and regulatory strategy of a textile engineered silk implant for tissue regeneration of injured human ACL (anterior cruciate ligament)}, abstract = {61 a93591 27-SY-1 Regenerative silk ligament: scale up and regulatory strategy of a textile engineered silk implant for tissue regeneration of injured human ACL (anterior cruciate ligament) Bernhard K{\"u}enburgļ¼ŒAndreas Teuschl MorphoMed, Austria In the USA around 370.000 annual ACL ruptures in the predominately young population (age 18-30) following sport injuries cause a lot of pain and long term troubles for the affected patients. The well established standard procedure of autologous tissue transplantation stabilizes the knee and allows sport activities after 9-12 months. However, harvest of autologous tissue such as patellar tendon or semitendinosus (the most frequently used autograft) weakens other body areas and long term data show an increased rate of arthroses (up to 50\% after 10 years) associated with ACL reconstructions. Based on numerous preclinical data and data from a 12-month sheep study the scale-up as well as regulatory approval process of a novel textile engineered silk implant as ACL graft have been initiated. It is planned to enter a clinical trial and strive for regulatory approval as a medical class 3 implant. The sheep data (1) have revealed an approximately 50\% degradation of the purified medical silk, which acts as scaffold for the regrowth of a new endogenous ligament. The formation of oriented collagenous tissue fibers including vascularization proves a ligament tissue regeneration for the first time. Scale-up and implementation of a commercial process require a defined set of specifications of commercial silkworm (Bombyx mori) silk, a biological raw material sourced from the textile industry as well as adequate analytical methods to characterize the depletion of sericin in the course of the production process. Based on first full scale samples, the defined biocompatibility program has to be executed, in the EU following the ISO requirements of the notified bodies, in the USA determined by the FDA. Upon submission of the full technical documentation as well as the biocompati-bility data, approval of a clinical trial can be achieved in order to demonstrate the clinical efficacy of the silk based ACL graft compared to the gold standard method in two different randomized groups. As primary endpoint the knee stability will be tested by an apparatus supported Lachmann test. In this study, besides the clinical benefit the patient safety is an important goal. The results of this study will be used for achievement of regulatory approval. References: 1) Teuschl A, Heimel P, N{\"u}rnberger S, van Griensven M, Redl H, Nau T. Am. J. Sports Med. 2016;44:1547-57. 2) Teuschl AH, van Griensven M, Redl H. Tissue Eng. Part C Methods. 2014;20:431-9.}, subject = {Biomaterial}, language = {en} } @misc{WilfingFruehwirthLehner, author = {Wilfing, Julia and Fr{\"u}hwirth, Clemens and Lehner, Benjamin}, title = {Feldmessungen der Gleit- und Haftreibungskoeffizienten von Skitourenfellen}, subject = {Skiing}, language = {de} } @article{HackethalMuehlederHoferetal., author = {Hackethal, Johannes and M{\"u}hleder, Severin and Hofer, Alexandra and Schneider, Karl Heinrich and Pr{\"u}ller, Johanna and Hennerbichler, Simone and Redl, Heinz and Teuschl, Andreas}, title = {An Effective Method of Atelocollagen Type 1/3 Isolation from Human Placenta and Its In Vitro Characterization in Two-Dimensional and Three-Dimensional Cell Culture Applications}, series = {Tissue Eng Part C Methods}, volume = {23}, journal = {Tissue Eng Part C Methods}, number = {5}, pages = {274 -- 285}, subject = {Placenta}, language = {en} }