@article{TomaschMaleinerHeheretal., author = {Tomasch, Janine and Maleiner, Babette and Heher, Philipp and Rufin, Manuel and Andriotis, Orestis G. and Thurner, Philipp J. and Redl, Heinz and Fuchs, Christiane and Teuschl-Woller, Andreas H.}, title = {Changes in Elastic Moduli of Fibrin Hydrogels Within the Myogenic Range Alter Behavior of Murine C2C12 and Human C25 Myoblasts Differently}, series = {Froniers in Bioengineering and Biotechnology}, volume = {10}, journal = {Froniers in Bioengineering and Biotechnology}, pages = {836520}, abstract = {Fibrin hydrogels have proven highly suitable scaffold materials for skeletal muscle tissue engineering in the past. Certain parameters of those types of scaffolds, however, greatly affect cellular mechanobiology and therefore the myogenic outcome. The aim of this study was to identify the influence of apparent elastic properties of fibrin scaffolds in 2D and 3D on myoblasts and evaluate if those effects differ between murine and human cells. Therefore, myoblasts were cultured on fibrin-coated multiwell plates ("2D") or embedded in fibrin hydrogels ("3D") with different elastic moduli. Firstly, we established an almost linear correlation between hydrogels' fibrinogen concentrations and apparent elastic moduli in the range of 7.5 mg/ml to 30 mg/ml fibrinogen (corresponds to a range of 7.7-30.9 kPa). The effects of fibrin hydrogel elastic modulus on myoblast proliferation changed depending on culture type (2D vs 3D) with an inhibitory effect at higher fibrinogen concentrations in 3D gels and vice versa in 2D. The opposite effect was evident in differentiating myoblasts as shown by gene expression analysis of myogenesis marker genes and altered myotube morphology. Furthermore, culture in a 3D environment slowed down proliferation compared to 2D, with a significantly more pronounced effect on human myoblasts. Differentiation potential was also substantially impaired upon incorporation into 3D gels in human, but not in murine, myoblasts. With this study, we gained further insight in the influence of apparent elastic modulus and culture type on cellular behavior and myogenic outcome of skeletal muscle tissue engineering approaches. Furthermore, the results highlight the need to adapt parameters of 3D culture setups established for murine cells when applied to human cells.}, subject = {Tissue Engineering}, language = {en} } @article{AngelovaDaskalovaFilipovetal., author = {Angelova, Liliya and Daskalova, Albena and Filipov, Emil and Monforte Vila, Xavier and Tomasch, Janine and Avdeev, Georgi and Teuschl-Woller, Andreas Herbert and Buchvarov, Ivan}, title = {Optimizing the Surface Structural and Morphological Properties of Silk Thin Films via Ultra-Short Laser Texturing for Creation of Muscle Cell Matrix Model}, series = {Polymers}, volume = {2022}, journal = {Polymers}, number = {14(13), 2584}, abstract = {Temporary scaffolds that mimic the extracellular matrix's structure and provide a stable substratum for the natural growth of cells are an innovative trend in the field of tissue engineering. The aim of this study is to obtain and design porous 2D fibroin-based cell matrices by femtosecond laser-induced microstructuring for future applications in muscle tissue engineering. Ultra-fast laser treatment is a non-contact method, which generates controlled porosity-the creation of micro/nanostructures on the surface of the biopolymer that can strongly affect cell behavior, while the control over its surface characteristics has the potential of directing the growth of future muscle tissue in the desired direction. The laser structured 2D thin film matrices from silk were characterized by means of SEM, EDX, AFM, FTIR, Micro-Raman, XRD, and 3D-roughness analyses. A WCA evaluation and initial experiments with murine C2C12 myoblasts cells were also performed. The results show that by varying the laser parameters, a different structuring degree can be achieved through the initial lifting and ejection of the material around the area of laser interaction to generate porous channels with varying widths and depths. The proper optimization of the applied laser parameters can significantly improve the bioactive properties of the investigated 2D model of a muscle cell matrix. Keywords: biopolymers; femtosecond laser processing; muscle cell matrix 2D model; muscle tissue engineering; silk fibroin.}, subject = {Tissue Engineering}, language = {en} } @article{MunschGruarinNateqietal., author = {Munsch, Nicolas and Gruarin, Stefanie and Nateqi, Jama and Lutz, Thomas and Binder, Michael and Aberle, Judith H. and Martin, Alistair and Knapp, Bernhard}, title = {Symptoms associated with a COVID-19 infection among a non-hospitalized cohort in Vienna}, series = {Wiener Klinische Wochenschrift / The Central European Journal of Medicine}, volume = {2022}, journal = {Wiener Klinische Wochenschrift / The Central European Journal of Medicine}, number = {134 (9-10)}, publisher = {Springer}, pages = {344 -- 350}, abstract = {Background: Most clinical studies report the symptoms experienced by those infected with coronavirus disease 2019 (COVID-19) via patients already hospitalized. Here we analyzed the symptoms experienced outside of a hospital setting. Methods: The Vienna Social Fund (FSW; Vienna, Austria), the Public Health Services of the City of Vienna (MA15) and the private company Symptoma collaborated to implement Vienna's official online COVID-19 symptom checker. Users answered 12 yes/no questions about symptoms to assess their risk for COVID-19. They could also specify their age and sex, and whether they had contact with someone who tested positive for COVID-19. Depending on the assessed risk of COVID-19 positivity, a SARS-CoV‑2 nucleic acid amplification test (NAAT) was performed. In this publication, we analyzed which factors (symptoms, sex or age) are associated with COVID-19 positivity. We also trained a classifier to correctly predict COVID-19 positivity from the collected data. Results: Between 2 November 2020 and 18 November 2021, 9133 people experiencing COVID-19-like symptoms were assessed as high risk by the chatbot and were subsequently tested by a NAAT. Symptoms significantly associated with a positive COVID-19 test were malaise, fatigue, headache, cough, fever, dysgeusia and hyposmia. Our classifier could successfully predict COVID-19 positivity with an area under the curve (AUC) of 0.74. Conclusion: This study provides reliable COVID-19 symptom statistics based on the general population verified by NAATs. Keywords: Chatbot; Machine learning; Self-reported; Symptom assessment; Symptom checker.}, subject = {COVID-19}, language = {en} } @article{KubaPanholzer, author = {Kuba, Markus and Panholzer, Alois}, title = {On bucket increasing trees, clustered increasing trees and increasing diamonds}, series = {Combinatorics, Probability and Computing}, journal = {Combinatorics, Probability and Computing}, number = {Volume 31 , Issue 4}, pages = {629 -- 661}, abstract = {In this work we analyse bucket increasing tree families. We introduce two simple stochastic growth processes, generating random bucket increasing trees of size n, complementing the earlier result of Mahmoud and Smythe (1995, Theoret. Comput. Sci.144 221-249.) for bucket recursive trees. On the combinatorial side, we define multilabelled generalisations of the tree families d-ary increasing trees and generalised plane-oriented recursive trees. Additionally, we introduce a clustering process for ordinary increasing trees and relate it to bucket increasing trees. We discuss in detail the bucket size two and present a bijection between such bucket increasing tree families and certain families of graphs called increasing diamonds, providing an explanation for phenomena observed by Bodini et al. (2016, Lect. Notes Comput. Sci.9644 207-219.). Concerning structural properties of bucket increasing trees, we analyse the tree parameter Kn . It counts the initial bucket size of the node containing label n in a tree of size n and is closely related to the distribution of node types. Additionally, we analyse the parameters descendants of label j and degree of the bucket containing label j, providing distributional decompositions, complementing and extending earlier results (Kuba and Panholzer (2010), Theoret. Comput. Sci.411(34-36) 3255-3273.).}, subject = {bucket-increasing-trees}, language = {en} } @article{Huber, author = {Huber, Albert}, title = {Remark on the quasilocal calculation of tidal heating: Energy transfer through the quasilocal surface}, series = {American Physical Society - Physical Review D}, volume = {105}, journal = {American Physical Society - Physical Review D}, number = {2}, abstract = {In this paper, using the quasilocal formalism of Brown and York, the flow of energy through a closed surface containing a gravitating physical system is calculated in a way that augments earlier results on the subject by Booth and Creighton. To this end, by performing a variation of the total gravitational Hamiltonian (bulk plus boundary part), it is shown that associated tidal heating and deformation effects generally are larger than expected. This is because the aforementioned variation leads to previously unrecognized correction terms, including a bulk-to-boundary inflow term that does not appear in the original calculation of the time derivative of the Brown-York energy and leads to corrective extensions of Einstein's quadrupole formula in the large sphere limit.}, subject = {gravitation}, language = {en} } @article{MairhoferPasson, author = {Mairhofer, Lukas and Passon, Oliver}, title = {Reconsidering the Relation Between "Matter Wave Interference" and "Wave-Particle Duality"}, series = {Foundations of Physics}, journal = {Foundations of Physics}, number = {52/32}, publisher = {Springer}, abstract = {Interference of more and more massive objects provides a spectacular confirmation of quantum theory. It is usually regarded as support for "wave-particle duality" and in an extension of this duality even as support for "complementarity". We first give an outline of the historical development of these notions. Already here it becomes evident that they are hard to define rigorously, i.e. have mainly a heuristic function. Then we discuss recent interference experiments of large and complex molecules which seem to support this heuristic function of "duality". However, we show that in these experiments the diffraction of a delocalized center-of-mass wave function depends on the interaction of the localized structure of the molecule with the diffraction element. Thus, the molecules display "dual features" at the same time, which contradicts the usual understanding of wave-particle duality. We conclude that the notion of "wave-particle duality" deserves no place in modern quantum physics.}, subject = {Quantenmechanik}, language = {en} } @article{Kuba, author = {Kuba, Markus}, title = {On multisets, interpolated multiple zeta values and limit laws.}, series = {Electronic Journal of Combinatorics}, journal = {Electronic Journal of Combinatorics}, number = {Vol. 29, Issue 1}, abstract = {In this work we discuss a parameter σ on weighted k-element multisets of [n]={1,…,n}. The sums of weighted k-multisets are related to k-subsets, k-multisets, as well as special instances of truncated interpolated multiple zeta values. We study properties of this parameter using symbolic combinatorics. We rederive and extend certain identities for ζtn({m}k). Moreover, we introduce random variables on the k-element multisets and derive their distributions, as well as limit laws for k or n tending to infinity.}, subject = {k-multisets}, language = {en} } @misc{Mairhofer, author = {Mairhofer, Lukas}, title = {Dying Experiments}, subject = {Experimentalsysteme}, language = {en} } @article{PurtscherRothbauerKratzetal., author = {Purtscher, Michaela and Rothbauer, Mario and Kratz, Sebastian Rudi Adam and Bailey, Andrew and Lieberzeit, Peter and Ertl, Peter}, title = {A microfluidic impedance-based extended infectivity assay: combining retroviral amplification and cytopathic effect monitoring on a single lab-on-a-chip platform}, series = {Lab on a Chip}, volume = {2021}, journal = {Lab on a Chip}, number = {Issue 7}, pages = {1364 -- 1372}, abstract = {Detection, quantification and monitoring of virus - host cell interactions are of great importance when evaluating the safety of pharmaceutical products. With the wide usage of viral based vector systems in combination with mammalian cell lines for the production of biopharmaceuticals, the presence of replication competent viral particles needs to be avoided and potential hazards carefully assessed. Consequently, regulatory agencies recommend viral clearance studies using plaque assays or TCID50 assays to evaluate the efficiency of the production process in removing viruses. While plaque assays provide reliable information on the presence of viral contaminations, they are still tedious to perform and can take up to two weeks to finish. To overcome some of these limitations, we have automated, miniaturized and integrated the dual cell culture bioassay into a common lab-on-a-chip platform containing embedded electrical sensor arrays to enrich and detect infectious viruses. Results of our microfluidic single step assay show that a significant reduction in assay time down to 3 to 4 days can be achieved using simultaneous cell-based viral amplification, release and detection of cytopathic effects in a target cell line. We further demonstrate the enhancing effect of continuous fluid flow on infection of PG-4 reporter cells by newly formed and highly active virions by M. dunni cells, thus pointing to the importance of physical relevant viral-cell interactions.}, subject = {Tissue Engineering}, language = {en} } @article{DeiningerWagnerHeimeletal., author = {Deininger, Christian and Wagner, Andrea and Heimel, Patrick and Salzer, Elias and Monforte Vila, Xavier and Weißenbacher, Nadja and Grillari, Johannes and Redl, Heinz and Wichlas, Florian and Freude, Thomas and Tempfer, Herbert and Teuschl-Woller, Andreas and Traweger, Andreas}, title = {Enhanced BMP-2-Mediated Bone Repair Using an Anisotropic Silk Fibroin Scaffold Coated with Bone-like Apatite}, series = {Int. J. Mol. Sci.}, volume = {23}, journal = {Int. J. Mol. Sci.}, number = {1 / 283}, abstract = {The repair of large bone defects remains challenging and often requires graft material due to limited availability of autologous bone. In clinical settings, collagen sponges loaded with excessive amounts of bone morphogenetic protein 2 (rhBMP-2) are occasionally used for the treatment of bone non-unions, increasing the risk of adverse events. Therefore, strategies to reduce rhBMP-2 dosage are desirable. Silk scaffolds show great promise due to their favorable biocompatibility and their utility for various biofabrication methods. For this study, we generated silk scaffolds with axially aligned pores, which were subsequently treated with 10× simulated body fluid (SBF) to generate an apatitic calcium phosphate coating. Using a rat femoral critical sized defect model (CSD) we evaluated if the resulting scaffold allows the reduction of BMP-2 dosage to promote efficient bone repair by providing appropriate guidance cues. Highly porous, anisotropic silk scaffolds were produced, demonstrating good cytocompatibility in vitro and treatment with 10× SBF resulted in efficient surface coating. In vivo, the coated silk scaffolds loaded with a low dose of rhBMP-2 demonstrated significantly improved bone regeneration when compared to the unmineralized scaffold. Overall, our findings show that this simple and cost-efficient technique yields scaffolds that enhance rhBMP-2 mediated bone healing.}, subject = {Tissue Engineering}, language = {en} } @article{HackethalDungelTeuschl, author = {Hackethal, Johannes and Dungel, Peter and Teuschl, Andreas Herbert}, title = {Frequently Used Strategies to Isolate Extracellular Matrix Proteins from Human Placenta and Adipose Tissue}, series = {Tissue Engineering Part C: Methods}, volume = {27}, journal = {Tissue Engineering Part C: Methods}, number = {12}, pages = {649 -- 660}, abstract = {The natural extracellular matrix (ECM) provides the optimal environment for cells. Many enzymatic or non-enzymatic based strategies to extract ECM proteins from tissues were published over the past years. However, every single isolation strategy reported so far is associated with specific bottlenecks. In this study, frequently used strategies to isolate ECM from human placenta or adipose tissue using Tris-, serum-, or pepsin-based buffers were compared. The resulting ECM proteins were biochemically characterized by analysis of cellular remnants using Hoechst DNA staining, glycosaminoglycan (GAG) content by dimethylmethylene blue, visualization of protein bands using sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis combined with amino acid quantification, and assessment of the proangiogenic profile using an angiogenesis array. Tris-NaCl-extracted ECM proteins showed a high heterogenic degree of extracted proteins, bioactive growth factors, and GAGs, but no collagen-I. Active serum-extracted ECM showed significant lower DNA remnants when compared with the Tris-NaCl isolation strategy. Pepsin-extracted ECM was rich in collagen-I and low amounts of remaining bioactive growth factors. This strategy was most effective to reduce DNA amounts when compared with the other isolation strategies. Pepsin-extracted ECM from both tissues easily gelled at 37°C, whereas the other extracted ECM strategies did not gel at 37°C (Tris-NaCl: liquid; serum: sponge). All relevant characteristics (DNA residues, ECM diversity and bioactivity, shape) of the extracted ECM proteins highly depend on its isolation strategy and could still be optimized. Impact statement The natural human extracellular matrix (ECM) is the ideal cell niche. Various strategies were reported to isolate human ECM components from various sources. In this article, we compared frequently used methods and compared their characteristics (DNA remnants, glycosaminoglycan content, sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis, amino acid quantification, angiogenesis array, and gel formation). We conclude that more research is still necessary to optimize current isolation approaches for in vitro or in vivo applications of human ECM.}, subject = {Tissue Engineering}, language = {en} } @article{SimboeckMarksteinerMachaceketal., author = {Simb{\"o}ck, Elisabeth and Marksteiner, Jessica and Machacek, Thomas and Wiessner, Katharina and Gepp, Barbara and Jesenberger, Veronika and Weihs, Anna and Leitner, Rita}, title = {The Power of Problem Based Learning beyond its Didactic Attributes}, series = {Journal of Problem Based Learning in Higher Education (JPBLHE)}, volume = {9}, journal = {Journal of Problem Based Learning in Higher Education (JPBLHE)}, number = {1}, pages = {109 -- 130}, abstract = {Hybrid courses with a focus on practice-orientated education and self-guided learning phases are on the rise on the higher education sector. Disciplines in Life Sciences implicate a high degree of practical laboratory expertise. The University of Applied Sciences (UAS) in Vienna, Austria, has thus been endeavoured offering students a high qualitative education integrating hybrid courses based on PBL principles, which consist of on-site (including the transmission of necessary background and practical laboratory training) and off-site (including self-study phases) sessions. As practical laboratory units are central in those courses, the restrictive measures, including the transition to a complete online teaching format due to the first Covid-19-pandemic lock-down, had severe effects on the implementation and the quality of the curriculum. According to surveys made specifically to address this problematic situation, it can be concluded that on-site practical units are fundamental for certain disciplines such as Life Sciences.}, subject = {Problem-based Learning}, language = {en} } @inproceedings{JakischKrammerKraetzetal., author = {Jakisch, Philipp and Krammer, Christopher and Kr{\"a}tz, Thomas and Stukelj, Gasper and Werdenits, Lukas and H{\"o}ller, Roland and R{\"o}ssler, Peter}, title = {Field Programmable Analog Circuits and Arrays - An Overview}, series = {Proceedings of the IEEE International Conference on Electrical, Computer and Energy Technologies (ICECET), Cape Town, South Africa, Dec. 9-10, 2021}, booktitle = {Proceedings of the IEEE International Conference on Electrical, Computer and Energy Technologies (ICECET), Cape Town, South Africa, Dec. 9-10, 2021}, pages = {6}, subject = {Field Programmable Analog Arrays}, language = {en} } @article{RauerKroissKryvinskaetal., author = {Rauer, Johannes Nikolaus and Kroiss, Michael and Kryvinska, Natalia and Engelhardt-Nowitzki, Corinna and Aburaia, Mohamed}, title = {Cross-university virtual teamwork as a means of internationalization at home}, series = {The International Journal of Management Education, Volume 19, Issue 3}, journal = {The International Journal of Management Education, Volume 19, Issue 3}, number = {Issue 3}, subject = {Virtual Teamwork}, language = {en} } @article{VeiglKlausAigneretal., author = {Veigl, Christoph and Klaus, Benjamin and Aigner, Benjamin and Wagner, Manuel}, title = {Universal Access Panel: A Novel Approach for Accessible Smart Homes and IoT}, series = {Computers Helping People with Special Needs. ICCHP-AAATE 2022. Lecture Notes in Computer Science}, volume = {2022}, journal = {Computers Helping People with Special Needs. ICCHP-AAATE 2022. Lecture Notes in Computer Science}, number = {Vol. 13342}, subject = {Home appliances}, language = {en} } @article{Wala, author = {Wala, Thomas}, title = {Die betriebswirtschaftliche Klausur: Rechnungswesen und Controlling}, series = {WISU - Das Wirtschaftsstudium}, journal = {WISU - Das Wirtschaftsstudium}, number = {2 / 2022}, pages = {198 ff}, subject = {Rechnungswesen}, language = {de} } @article{Lang, author = {Lang, Moritz}, title = {The mechanism of scale-invariance}, series = {Automatica}, volume = {140}, journal = {Automatica}, number = {June 2022}, abstract = {A system is invariant with respect to an input transformation if we can transform any dynamic input by this function and obtain the same output dynamics after adjusting the initial conditions appropriately. Often, the set of all such input transformations forms a Lie group, the most prominent examples being scale-invariant (, ) and translational-invariant () systems, the latter comprising linear systems with transfer function zeros at the origin. Here, we derive a necessary and sufficient normal form for invariant systems and, by analyzing this normal form, provide a complete characterization of the mechanism by which invariance can be achieved. In this normal form, all invariant systems (i) estimate the applied input transformation by means of an integral feedback, and (ii) then apply the inverse of this estimate to the input before processing it in any other way. We demonstrate our results based on three examples: a scale-invariant "feed-forward loop", a bistable switch, and a system resembling the core of the mammalian circadian network.}, subject = {Invariant systems}, language = {en} } @inproceedings{WalaSalmen, author = {Wala, Thomas and Salmen, Christine}, title = {Entrepreneurship Education and Innovation Transfer Through Student Practice Projects}, series = {Mobility for Smart Cities and Regional Development - Challenges for Higher Education. ICL 2021. Lecture Notes in Networks and Systems, Vol. 390}, booktitle = {Mobility for Smart Cities and Regional Development - Challenges for Higher Education. ICL 2021. Lecture Notes in Networks and Systems, Vol. 390}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-93906-9}, pages = {858 -- 868}, abstract = {Entrepreneurs keep the economy and society going by implementing new ideas. Entrepreneurship competencies such as creativity, risk tolerance or perseverance do not only emerge in professional life, but are already developed in early phases of socialization. Entrepreneurship education with its strongly action-oriented teaching and learning formats plays a triggering and process-reinforcing role in this respect. However, the competencies acquired through entrepreneurship education are also increasingly important for successful action in dependent employment. This article first shows that the goals and means of Entrepreneurship Education harmonize with the high practical relevance of teaching required by the Austrian Universities of Applied Sciences Act. Against this background, a concrete example of implementation is used to illustrate how the curricular anchoring of a student project in an engineering course can promote not only the practical relevance of teaching, but also the teaching of entrepreneurial competencies and the transfer of innovation between the university and industry.}, subject = {Entrepreneurship education}, language = {en} } @article{Wala, author = {Wala, Thomas}, title = {Fitness im B{\"u}ro mit Active Workplace Design}, series = {Wirtschaft und Management : Schriftenreihe zur wirtschaftswissenschaftlichen Forschung und Praxis}, journal = {Wirtschaft und Management : Schriftenreihe zur wirtschaftswissenschaftlichen Forschung und Praxis}, number = {31}, pages = {47 -- 58}, abstract = {Wissensarbeiter:innen verbringen den {\"u}berwiegenden Teil ihrer Arbeitszeit sitzend vor dem Computer. Die negativen Folgen von langem Sitzen f{\"u}r die Gesundheit sind bekannt: Zu langes Sitzen bedingt einen niedrigen Kalorienverbrauch, der Stoffwechsel und das Herz-Kreislaufsystem laufen auf Sparflamme. Entsprechend steigt das Risiko f{\"u}r {\"U}bergewicht, Diabetes, Bandscheibenvorfall und Herz-Kreislauf- Erkrankungen. Unter den Folgen von langem Sitzen leiden aber nicht nur die betroffenen Mitarbeiter:innen selbst, sondern auch deren Arbeitgeber:innen, weil Mitarbeiter:innen mit einem auf Bewegungsmangel zur{\"u}ckzuf{\"u}hrenden reduzierten physischen und psychischen Wohlbefinden weniger produktiv und kreativ arbeiten bzw. aufgrund von Erkrankungen erst gar nicht arbeiten k{\"o}nnen. Der vorliegende Beitrag zeigt auf, wie Unternehmen durch das Setzen sanfter Bewegungszw{\"a}nge, den Einsatz dynamischer Arbeitsstationen sowie die Integration niederschwelliger Fitnessmodule in die B{\"u}rolandschaft f{\"u}r mehr k{\"o}rperliche Aktivit{\"a}t im Arbeitsalltag sorgen k{\"o}nnen.}, subject = {Arbeitsplatz}, language = {de} } @article{Huber, author = {Huber, Albert}, title = {Hidden Killing fields, geometric symmetries and black hole mergers}, series = {Annals of Physics}, volume = {434}, journal = {Annals of Physics}, pages = {17}, abstract = {In the present work, using the recently introduced framework of local geometric deformations, special types of vector fields - so-called hidden Killing vector fields - are constructed, which solve the Killing equation not globally, but only locally, i.e. in local subregions of spacetime. Taking advantage of the fact that the vector fields coincide locally with Killing fields and therefore allow the consideration of integral laws that convert into exact physical conservation laws on local scales, balance laws in dynamical systems without global Killing symmetries are derived that mimic as closely as possible the conservation laws for energy and angular momentum of highly symmetric models. The utility of said balance laws is demonstrated by a concrete geometric example, namely a toy model for the binary merger of two extremal Reissner-Nordstr{\"o}m black holes.}, subject = {Hidden Killing}, language = {en} } @incollection{LehnerSohm, author = {Lehner, Martin and Sohm, Kurt}, title = {Qualit{\"a}t, didaktische Methodik und Digitalit{\"a}t}, series = {Wie Corona die Hochschullehre ver{\"a}ndert: Erfahrungen und Gedanken aus der Krise zum zuk{\"u}nftigen Einsatz von eLearning}, booktitle = {Wie Corona die Hochschullehre ver{\"a}ndert: Erfahrungen und Gedanken aus der Krise zum zuk{\"u}nftigen Einsatz von eLearning}, publisher = {Springer Gabler}, publisher = {Fachhochschule Technikum Wien}, pages = {339 -- 350}, subject = {Hochschuldidaktik}, language = {de} } @article{Wala, author = {Wala, Thomas}, title = {Die betriebswirtschaftliche Klausur: Rechnungswesen und Controlling}, series = {WISU}, volume = {2}, journal = {WISU}, pages = {198 -- 200}, subject = {Rechnungswesen}, language = {de} } @article{Wala, author = {Wala, Thomas}, title = {Die betriebswirtschaftliche Klausur: Kostenmanagement.}, series = {WISU}, journal = {WISU}, number = {6}, pages = {686 -- 688}, subject = {Kostenmanagement}, language = {de} } @book{WalaHaslehnerHirsch, author = {Wala, Thomas and Haslehner, Franz and Hirsch, Manuela}, title = {Kostenrechnung, Budgetierung und Kostenmanagement}, publisher = {Linde}, address = {Wien}, isbn = {9783714303117}, publisher = {Fachhochschule Technikum Wien}, subject = {Kostenrechnung}, language = {de} } @article{HagauerMatlschweigerTippelreitheretal., author = {Hagauer, Josef and Matlschweiger, Ulrich and Tippelreither, Christian and Lutz, Markus and Hribernig, Thomas and Lackner, Maximilian}, title = {Controlling Metal Fires through Cellulose Flake Blanketing Followed by Water Spray Cooling}, series = {Fire}, volume = {5}, journal = {Fire}, number = {3}, doi = {10.3390/fire5030083}, abstract = {The traditional methods of fighting metal fires are not always safe for firefighters. The sand and salts that are thrown onto the fire to suffocate the flames can lead to splashes of molten metal, putting the firefighters and the surroundings at risk. A novel process is described where magnesium fires are brought under control using a simple two-step process. First, coated cellulose flakes, which contain approx. 30\% inorganic salts, are blown onto the fire from a distance of several meters. Due to its low bulk density, the material settles smoothly on the fire and immediately covers the flames for several seconds. Before the hot metal can break through this cover, a fine water spray is applied to the fire. The water spray wets the top layer of the cellulose flakes, which will begin to char from the bottom. The water evaporates from within the cellulose flake layer and withdraws heat. It was observed that no hydrogen is formed and that this technique can safely control fires. It is judged that 90 kg of flakes could safely bring a pile of 75 kg of burning Mg flakes under control. By using a pneumatic conveying unit for the flakes, firefighters can effectively and efficiently cover the flames from a safe distance. This novel method could be recommended to firefighters in industrial magnesium processing plants, as well as local firefighters in the vicinity of such plants.}, subject = {magnesium fire}, language = {en} } @inproceedings{TabakovicCsapo, author = {Tabakovic, Momir and Csapo, Csilla}, title = {Industry - University cooperation in the renewable energy field in south Africa- Gap analysis and enhancement proposals}, series = {UNITO conference, Webinar, Universities of Tomorrow: Global, Interdisciplinary, Digitized, Sustainable, HTWG Konstanz}, booktitle = {UNITO conference, Webinar, Universities of Tomorrow: Global, Interdisciplinary, Digitized, Sustainable, HTWG Konstanz}, subject = {Renewable Energies}, language = {en} } @inproceedings{ValckenborgBergerUjvarietal., author = {Valckenborg, Roland and Berger, Karl A. and {\´U}jv{\´a}ri, Guszt{\´a}v and Eder, Gabriele C. and Gaisberger, Lukas and Tabakovic, Momir and Polo Lopez, Christina S. and Boddaert, Simon and del Buono, Matteo and Mart{\´i}n Chivelet, Nuria and Sanz Martinez, Asier and Kim, Jun-Tae and Gerd Imenes, Anne}, title = {COMPARISON OF IEC 61853-1 MATRIX EVALUATIONS BASED ON INDOOR AND OUTDOOR MEASUREMENT DATA FROM PVPS TASK 15 BIPV ROUND-ROBIN}, series = {38th European Photovoltaic Solar Energy Conference Proceedings, September 6-10, 2021}, booktitle = {38th European Photovoltaic Solar Energy Conference Proceedings, September 6-10, 2021}, subject = {Measurement}, language = {en} } @inproceedings{BraunLeeRohatsch, author = {Braun, Robert and Lee, Barbara and Rohatsch, Lukas}, title = {Governance challenges of urban dataspace - transdisciplinary perspectives}, series = {Extended Abstracts EU-SPRI Conference 2022}, booktitle = {Extended Abstracts EU-SPRI Conference 2022}, pages = {105 -- 107}, subject = {Urban Data Space}, language = {en} } @misc{Rohatsch, author = {Rohatsch, Lukas}, title = {Technical perspective of Data Spaces}, subject = {Data Spaces}, language = {en} } @inproceedings{SchwaigerAburaiaAburaiaetal., author = {Schwaiger, Simon and Aburaia, Mohamed and Aburaia, Ali and W{\"o}ber, Wilfried}, title = {Explainable Artificial Intelligence for Robot Arm Control}, series = {Proceedings of the 32nd International DAAAM Virtual Symposium `Intelligent Manufacturing \& Automation`, 28-29th October 2021, Vienna}, volume = {32}, booktitle = {Proceedings of the 32nd International DAAAM Virtual Symposium `Intelligent Manufacturing \& Automation`, 28-29th October 2021, Vienna}, number = {1}, pages = {0640 -- 0647}, subject = {Artificial Intelligence}, language = {en} } @article{LacknerLutzHribernig, author = {Lackner, Maximilian and Lutz, Markus and Hribernig, Thomas}, title = {Neuartiges Verfahren zum L{\"o}schen von Metallbr{\"a}nden mit Zelluloseflakes}, series = {Feuerwehr Fachjournal}, journal = {Feuerwehr Fachjournal}, number = {September 2021}, pages = {54}, subject = {Extinguisher}, language = {de} } @inproceedings{AbdankAburaiaWoeber, author = {Abdank, Moritz and Aburaia, Mohamed and W{\"o}ber, Wilfried}, title = {Using-Colour-Based Object Detection for Pick and Place Applications}, series = {Proceedings of the 32nd International DAAAM Virtual Symposium 'Intelligent Manufacturing \& Automation', 28-29th October 2021, Vienna}, volume = {32}, booktitle = {Proceedings of the 32nd International DAAAM Virtual Symposium 'Intelligent Manufacturing \& Automation', 28-29th October 2021, Vienna}, number = {1}, pages = {0536 -- 0541}, subject = {Computer Vision}, language = {en} } @inproceedings{RauhOrsolits, author = {Rauh, Sebastian and Orsolits, Horst}, title = {Perspectives on Virtual Reality in Higher Education for Robotics and Related Engineering Disciplines}, series = {Robotics in Education (International Conference on Robotics in Education)}, booktitle = {Robotics in Education (International Conference on Robotics in Education)}, publisher = {Springer}, isbn = {978-3-031-12848-6}, pages = {39 -- 51}, abstract = {Industrial engineering education has a strong focus on and affinity towards technology. While Virtual Reality hardware and applications advance and learning behaviour changes, it is particularly interesting to determine the possible use of Virtual Reality for teaching engineering subjects, for example fundamentals of robotics. This paper presents a study which examines the possible use of Virtual Reality learning environments at higher learning institutions. The study shows perspectives of students and lecturers and identifies opportunities and challenges for the use of Virtual Reality in industrial engineering education. The results of the indicated study show that the participants have a positive attitude towards Virtual Reality and strong motivation for in class use. The study results also suggest, that Virtual Reality content creation should be included in engineering curricula.}, subject = {Virtual reality}, language = {en} } @inproceedings{ChiritaTabakovic, author = {Chirita, Cristian and Tabakovic, Momir}, title = {Optimization of a simulation for thermoelectric generators and their application in water boiler systems with combustion chamber}, series = {X International Conference Industrial Engineering and Environmental Protection}, booktitle = {X International Conference Industrial Engineering and Environmental Protection}, pages = {143 -- 151}, subject = {Generators}, language = {en} } @techreport{OrsolitsKorn, author = {Orsolits, Horst and Korn, Alexander}, title = {Augmented Reality basierte Robotik-Lehre}, organization = {Gesellschaft f{\"u}r Informatik e.V., Wettbewerbsband AVRiL 2021}, pages = {8}, abstract = {Diese Arbeit beschreibt eine Augmented Reality (AR) Applikation f{\"u}r den Einsatz in der Hochschullehre zum Thema Industrierobotik. Ziel ist es, sowohl das Lehren als auch das Lernen grundlegender Robotik-Inhalte durch die Bereitstellung einer interaktiven Methode zur Vermittlung der Lehrinhalte f{\"u}r Studierende zu verbessern. Die Studierenden sind in der Lage, direkt mit dem virtuellen Modell eines Industrieroboters zu interagieren und so selbstgesteuert die Lerninhalte zu vertiefen. Diese interaktive Methode verbindet die Studierenden direkt mit den Lehrinhalten und f{\"o}rdert das selbsterforschende Lernen. Eine weitere Anwendungsm{\"o}glichkeit sieht die Kombination einer Lektorenversion der AR Experience mit der Studierendenversion vor. Der Lektor hat die M{\"o}glichkeit, das Modell in AR zu steuern bzw. zu ver{\"a}ndern und die Studierenden k{\"o}nnen auf Ihren Mobilger{\"a}ten die {\"A}nderungen live in AR mitverfolgen, um so auch im Distance Learning eine Verbindung Lektor - Studierende - Inhalt zus{\"a}tzlich zu Videokonferenz-Tools herzustellen.}, subject = {Augmented Reality}, language = {de} } @inproceedings{KlamertSchmidTraxlerLackner, author = {Klamert-Schmid, Judith and Traxler, Sabine and Lackner, Maximilian}, title = {The Phenomenon Of 'Opportunity Recognition' Among Engineering Student}, series = {24th International Conference on Interactive Collaborative Learning(ICL2021), 22.-24.September 2021, Dresden}, booktitle = {24th International Conference on Interactive Collaborative Learning(ICL2021), 22.-24.September 2021, Dresden}, address = {Dresden}, subject = {Engineering}, language = {en} } @article{KlamertSchmidLackner, author = {Klamert-Schmid, Judith and Lackner, Maximilian}, title = {Arbeiten und studieren im Homeoffice}, series = {Alle! Achtung! Das Sicherheitsmagazin der AUVA}, journal = {Alle! Achtung! Das Sicherheitsmagazin der AUVA}, number = {10/2021}, subject = {Home Office}, language = {de} } @article{AaliyaSunoojSriRajkumaretal., author = {Aaliya, Basheer and Sunooj, Kappat Valiyapeediyekkal and Sri Rajkumar, Chillapalli Babu and Navaf, Muhammed and Akhila, Plachikkattu Parambil and Sudheesh, Cherakkathodi and George, Johnsy and Lackner, Maximilian}, title = {Effect of Thermal Pretreatments on Phosphorylation of Corypha umbraculifera L. Stem Pith Starch: A Comparative Study Using Dry-Heat, Heat-Moisture and Autoclave Treatments}, series = {Polymers}, volume = {13}, journal = {Polymers}, number = {3855}, abstract = {Talipot starch, a non-conventional starch source with a high yield (76\%) from the stem pith of talipot palm (Corypha umbraculifera L.) was subjected to three different thermal treatments (dry-heat, heat-moisture and autoclave treatments) prior to phosphorylation. Upon dual modification of starch with thermal treatments and phosphorylation, the phosphorous content and degree of crosslinking significantly increased (p ≤ 0.05) and was confirmed by the increased peak intensity of P=O and P-O-C stretching vibrations compared to phosphorylated talipot starch in the FT-IR spectrum. The highest degree of crosslinking (0.00418) was observed in the autoclave pretreated phosphorylated talipot starch sample. Thermal pretreatment remarkably changed the granule morphology by creating fissures and grooves. The amylose content and relative crystallinity of all phosphorylated talipot starches significantly decreased (p ≤ 0.05) due to crosslinking by the formation of phosphodiester bonds, reducing the swelling power of dual-modified starches. Among all modified starches, dry-heat pretreated phosphorylated starch gel showed an improved light transmittance value of 28.4\%, indicating reduced retrogradation tendency. Pasting and rheological properties represented that the thermal pretreated phosphorylated starch formed stronger gels that improved thermal and shear resistance. Autoclave treatment before phosphorylation of talipot starch showed the highest resistant starch content of 48.08\%.}, subject = {Talipot starch}, language = {en} } @inproceedings{TabakovicWuerflGuerraetal., author = {Tabakovic, Momir and W{\"u}rfl, Marlen and Guerra, Eduardo and Gutleder, Miriam}, title = {Operating models for PV systems in existing residential building complexes in Vienna - challenges and opportunities}, series = {XI International Conference Industrial Engineering and Environmental Protection 2021 (IIZS 2021)}, booktitle = {XI International Conference Industrial Engineering and Environmental Protection 2021 (IIZS 2021)}, abstract = {This paper aims to identify challenges and opportunities that are associated with installing PV (Photovoltaic) systems in existing residential building complexes in Vienna. For this purpose, a project-oriented approach was chosen and hence a representative residential building complex in Vienna was chosen and analyzed to demonstrate the challenges that are associated with such projects. Furthermore, a particular focus lies on exploring different operating models that are available when it comes to the execution of such a project. As this paper builds on the rather novel topic of exploring new operating models for installing PV systems on existing residential building complexes in Vienna, many further suggestions for research can be identified that exceed the scope of this paper.}, subject = {Photovoltaics}, language = {en} } @inproceedings{KaufmannWahl, author = {Kaufmann, Christian and Wahl, Harald}, title = {A Technical Support to Enrich Existing Software Development Courses, with the Additional Topic of Secure Coding}, series = {In Proceedings of the iiWAS2021, 23rd International Conference on Information Integration and Web-based Applications \& Services, Linz, Austria, November 30 - December 01, 2021}, booktitle = {In Proceedings of the iiWAS2021, 23rd International Conference on Information Integration and Web-based Applications \& Services, Linz, Austria, November 30 - December 01, 2021}, pages = {519 -- 524}, subject = {Secure Code}, language = {en} } @article{PastekaSchoellbauerSantosdaCostaetal., author = {Pasteka, Richard and Sch{\"o}llbauer, Lara Alina and Santos da Costa, Joao Pedro and Kolar, Radim and Forjan, Mathias}, title = {Experimental Evaluation of Dry Powder Inhalers During In- and Exhalation Using a Model of the Human Respiratory System (xPULM™)}, series = {Pharmaceutics}, volume = {2022}, journal = {Pharmaceutics}, number = {14/3}, pages = {15}, abstract = {Dry powder inhalers are used by a large number of patients worldwide to treat respiratory diseases. The objective of this work is to experimentally investigate changes in aerosol particle diameter and particle number concentration of pharmaceutical aerosols generated by four dry powder inhalers under realistic inhalation and exhalation conditions. To simulate patients undergoing inhalation therapy, the active respiratory system model (xPULM™) was used. A mechanical upper airway model was developed, manufactured, and introduced as a part of the xPULM™ to represent the human upper respiratory tract with high fidelity. Integration of optical aerosol spectrometry technique into the setup allowed for evaluation of pharmaceutical aerosols. The results show that there is a significant difference (p < 0.05) in mean particle diameter between inhaled and exhaled particles with the majority of the particles depositing in the lung, while particles with the size of (>0.5 μm) are least influenced by deposition mechanisms. The fraction of exhaled particles ranges from 2.13\% (HandiHaler®) over 2.94\% (BreezHaler®), and 6.22\% (Turbohaler®) to 10.24\% (Ellipta®). These values are comparable to previously published studies. Furthermore, the mechanical upper airway model increases the resistance of the overall system and acts as a filter for larger particles (>3 μm). In conclusion, the xPULM™ active respiratory system model is a viable option for studying interactions of pharmaceutical aerosols and the respiratory tract regarding applicable deposition mechanisms. The model strives to support the reduction of animal experimentation in aerosol research and provides an alternative to experiments with human subjects.}, subject = {Biomedical Engineering}, language = {en} } @article{GraselBaptistaTragner, author = {Grasel, Bernhard and Baptista, Jos{\´e} and Tragner, Manfred}, title = {Supraharmonic and Harmonic Emissions of a Bi-Directional V2G Electric Vehicle Charging Station and Their Impact to the Grid Impedance}, series = {Energies}, volume = {15}, journal = {Energies}, number = {8}, doi = {10.3390/en15082920}, abstract = {Bidirectional electric vehicle supply equipment and charging stations (EVSE) offer new business models and can provide services to the electrical grid. The smart grid lab in Vienna gives unique testing possibilities of future smart grids, as different type of electrical equipment can be operated at a reconstructed, well-known distribution grid. In this work the harmonic and supraharmonic emissions of a bidirectional EVSE are measured according to IEC61000-4-7 and IEC61000-4-30 Ed3 standard as well as the high-frequency grid impedance. In addition, the efficiency and the power factor are determined at various operating points. Although THDi at nominal power (10 kW) is very low and the efficiency and power factor is very high, at low power levels the opposite situation arise. Supraharmonic emissions remain stable independent of the charging/discharging power, and both wideband and narrowband emissions occur. The additional capacitance when connecting the EVSE impacts the high-frequency grid impedance substantially and generates resonance points.}, subject = {power quality}, language = {en} } @article{WoeberMehnenCurtoetal., author = {W{\"o}ber, Wilfried and Mehnen, Lars and Curto, Manuel and Dias Tibihika, Papius and Tesfaye, Genanaw and Meimberg, Harald}, title = {Investigating Shape Variation Using Generalized Procrustes Analysis and Machine Learning}, series = {Applied Sciences}, volume = {2022}, journal = {Applied Sciences}, number = {12(6), 3158}, pages = {26}, abstract = {Abstract: The biological investigation of a population's shape diversity using digital images is typi- cally reliant on geometrical morphometrics, which is an approach based on user-defined landmarks. In contrast to this traditional approach, the progress in deep learning has led to numerous applications ranging from specimen identification to object detection. Typically, these models tend to become black boxes, which limits the usage of recent deep learning models for biological applications. However, the progress in explainable artificial intelligence tries to overcome this limitation. This study compares the explanatory power of unsupervised machine learning models to traditional landmark-based approaches for population structure investigation. We apply convolutional autoencoders as well as Gaussian process latent variable models to two Nile tilapia datasets to investigate the latent structure using consensus clustering. The explanatory factors of the machine learning models were extracted and compared to generalized Procrustes analysis. Hypotheses based on the Bayes factor are formulated to test the unambiguity of population diversity unveiled by the machine learning models. The findings show that it is possible to obtain biologically meaningful results relying on unsupervised machine learning. Furthermore we show that the machine learning models unveil latent structures close to the true population clusters. We found that 80\% of the true population clusters relying on the convolutional autoencoder are significantly different to the remaining clusters. Similarly, 60\% of the true population clusters relying on the Gaussian process latent variable model are significantly different. We conclude that the machine learning models outperform generalized Procrustes analysis, where 16\% of the population cluster was found to be significantly different. However, the applied machine learning models still have limited biological explainability. We recommend further in-depth investigations to unveil the explanatory factors in the used model. Keywords: generalized procrustes analysis; machine learning; convolutional autoencoder; Gaussian process latent variable models}, subject = {generalized procrustes analysis}, language = {en} } @inproceedings{HimmelstossVotzi, author = {Himmelstoß, Felix and Votzi, Helmut}, title = {A Floating Double Buck-Boost Converter as Driver for a Permanent Exited DC Machine}, series = {Proceedings of the 2021 International Conference on Electrical Drives \& Power Electronics (EDPE 2021), 22.-24. September 2021, Dubrovnik, Croatia}, booktitle = {Proceedings of the 2021 International Conference on Electrical Drives \& Power Electronics (EDPE 2021), 22.-24. September 2021, Dubrovnik, Croatia}, pages = {72 -- 77}, subject = {DC/DC converter}, language = {en} } @article{ShanReinersFabbianetal., author = {Shan, Yutong and Reiners, Ansgar and Fabbian, Damian and Marfil, Emilio and Montes, David and Tabernero, Hugo M. and Ribas, Ignasi and Caballero, Jose A. and Quirrenbach, Andreas and Amado, Pedro J. and Aceituno, Jesus and Bejar, Victor J. S. and Cortes-Contreras, Miriam and Dreizler, Stefan and Hatzes, Artie P. and Henning, Thomas and Jeffers, Sandra V. and Kaminski, Adrian and Kurster, Martin and Lafarga, Marina and Morales, Juan Carlos and Nagel, Evangelos and Palle, Enric and Passegger, Vera M. and Lopez, Cristina Rodriguez and Schweitzer, Andreas and Zechmeister, Mathias}, title = {The CARMENES search for exoplanets around M dwarfs Not-so-fine hyperfine-split vanadium lines in cool star spectra}, series = {Astronomy \& Astrophysics}, volume = {654}, journal = {Astronomy \& Astrophysics}, subject = {Atomic data}, language = {en} } @article{ZhangYaoMaetal., author = {Zhang, Hang and Yao, Yuan and Ma, Yingxin and Lackner, Maximilian and Jiang, Yunliang}, title = {A 3D printing tool-path generation strategy based on the partition of principal stress field for fused filament fabrication}, series = {The International Journal of Advanced Manufacturing Technology}, journal = {The International Journal of Advanced Manufacturing Technology}, number = {122}, pages = {1719 -- 1735}, abstract = {In order to enhance the strength of 3D-printed parts made of polymer materials and reduce the anisotropy caused by the fused filament fabrication process, this paper proposes an inter-layer interleaved composite path planning method based on the directional partition of the principal stress field. This method not only ensures intra-layer reinforcement under specific working conditions but also increases the strength of the printed part by enhancing the adhesion of adjacent layers through staggered filling between layers. The mechanical performance is improved by 10 to 30\% compared to other conventional filling patterns such as the zigzag filling algorithm. Inter-layer interleaved composite enhancement path planning method is suitable for path planning of structures with complex shapes and is easily integrated into existing general computer-aided engineering processes.}, subject = {Principal stress field}, language = {en} } @article{YalcinHimmelstoss, author = {Yalcin, Faruk and Himmelstoß, Felix}, title = {Boost Converter based 3-phase AC-AC Active Tracking Voltage Regulator Controlled by a Robust Hybrid Control Method}, series = {Sakarya University Journal of Science}, volume = {2022}, journal = {Sakarya University Journal of Science}, number = {26(1)}, pages = {24 -- 37}, subject = {AC-AC regulator}, language = {en} } @inproceedings{WidhalmGoeschkaKastner, author = {Widhalm, Dominik and Goeschka, Karl M. and Kastner, Wolfgang}, title = {Undervolting on wireless sensor nodes: a critical perspective}, series = {Proceedings of the 23rd International Conference on Distributed Computing and Networking (ICDCN 2022), 4-7 January 2022, Delhi, India}, booktitle = {Proceedings of the 23rd International Conference on Distributed Computing and Networking (ICDCN 2022), 4-7 January 2022, Delhi, India}, doi = {https://doi.org/10.1145/3491003.3491018}, pages = {8}, subject = {wireless sensor network}, language = {en} } @article{JohannesWeihsKarneretal., author = {Johannes, Hackethal and Weihs, Anna and Karner, Lisa and Metzger, Magdalena and Dungel, Peter and Hennerbichler, Simone and Redl, Heinz and Teuschl-Woller, Andreas Herbert}, title = {Novel Human Placenta-Based Extract for Vascularization Strategies in Tissue Engineering}, series = {Tissue Eng Part C Methods}, volume = {27}, journal = {Tissue Eng Part C Methods}, number = {11}, pages = {616 -- 632}, abstract = {There is critical unmet need for new vascularized tissues to support or replace injured tissues and organs. Various synthetic and natural materials were already established for use of two-dimensional (2D) and three-dimensional (3D) in vitro neovascularization assays, however, they still cannot mimic the complex functions of the sum of the extracellular matrix (ECM) in native intact tissue. Currently, this issue is only addressed by artificial products such as Matrigel™, which comprises a complex mixture of ECM proteins, extracted from animal tumor tissue. Despite its outstanding bioactivity, the isolation from tumor tissue hinders its translation into clinical applications. Since nonhuman ECM proteins may cause immune reactions, as are frequently observed in clinical trials, human ECM proteins represent the best option when aiming for clinical applications. Here, we describe an effective method of isolating a human placenta substrate (hpS) that induces the spontaneous formation of an interconnected network of green fluorescence-labeled human umbilical vein endothelial cells (gfpHUVECs) in vitro. The substrate was biochemically characterized by using a combination of bicinchoninic acid (BCA) assay, DNA, and glycosaminoglycan (GAG) content assays, sodium dodecyl sulfate/polyacrylamide gel electrophoresis (SDS-PAGE) analysis and Western blot, angiogenesis arrays, chromatographic thrombin detection, high performance liquid chromatography (HPLC)-based amino acid quantification analysis, and assessment of antimicrobial properties. 2D in vitro cell culture experiments have been performed to determine the vasculogenic potential of hpS, which demonstrated that cell networks developed on hpS show a significantly higher degree of complexity (number of tubules/junctions; total/mean tube length) when compared with Matrigel. As 3D cell culture techniques represent a more accurate representation of the in vivo condition, the substrate was 3D solidified using various natural polymers. 3D in vitro vasculogenesis assays have been performed by seeding gfpHUVECs in an hpS-fibrinogen clot. In conclusion, hpS provides a potent human/material-based alternative to xenogenic-material-based biomaterials for vascularization strategies in tissue engineering.}, subject = {Tissue Engineering}, language = {en} } @article{CubasArmasFabbian, author = {Cubas Armas, Melania and Fabbian, Damian}, title = {Do MURaM and STAGGER Simulations of Solar Faculae Match Observational Signatures from Magnetic Structures?}, series = {The Astrophysical Journal}, volume = {923}, journal = {The Astrophysical Journal}, number = {2}, abstract = {We compare results of simulations of solar facular-like conditions performed using the numerical codes MURaM and STAGGER. Both simulation sets have a similar setup, including the initial condition of ≈200 G vertical magnetic flux. After interpolating the output physical quantities to constant optical depth, we compare them and test them against inversion results from solar observations. From the snapshots, we compute the monochromatic continuum in the visible and infrared, and the full Stokes vector of the Fe i spectral line pair around 6301-6302 {\AA}. We compare the predicted spectral lines (at the simulation resolution and after smearing to the HINODE SP/SOT resolution) in terms of their main parameters for the Stokes I line profiles, and of their area and amplitude asymmetry for the Stokes V profiles. The codes produce magnetoconvection with similar appearance and distribution in temperature and velocity. The results also closely match the values from recent relevant solar observations. Although the overall distribution of the magnetic field is similar in both radiation-magnetohydrodynamic (RMHD) simulation sets, a detailed analysis reveals substantial disagreement in the field orientation, which we attribute to the differing boundary conditions. The resulting differences in the synthetic spectra disappear after spatial smearing to the resolution of the observations. We conclude that the two sets of simulations provide robust models of solar faculae. Nevertheless, we also find differences that call for caution when using results from RMHD simulations to interpret solar observational data.}, subject = {Magnetohydrodynamics}, language = {en} } @article{HeinzelOberhauserKeibletal., author = {Heinzel, Johannes Christoph and Oberhauser, Viola and Keibl, Claudia and Sch{\"a}dl, Barbara and Swiadek, Nicole V. and L{\"a}ngle, Gregor and Frick, Helen and Slezak, Cyrill and Prahm, Cosima and Grillari, Johannes and Kolbenschlag, Jonas and Hercher, David}, title = {ESWT Diminishes Axonal Regeneration following Repair of the Rat Median Nerve with Muscle-In-Vein Conduits but Not after Autologous Nerve Grafting}, series = {Biomedicines}, volume = {2022}, journal = {Biomedicines}, number = {10(8)}, pages = {1777}, abstract = {Investigations reporting positive effects of extracorporeal shockwave therapy (ESWT) on nerve regeneration are limited to the rat sciatic nerve model. The effects of ESWT on muscle-in-vein conduits (MVCs) have also not been investigated yet. This study aimed to evaluate the effects of ESWT after repair of the rat median nerve with either autografts (ANGs) or MVCs. In male Lewis rats, a 7 mm segment of the right median nerve was reconstructed either with an ANG or an MVC. For each reconstructive technique, one group of animals received one application of ESWT while the other rats served as controls. The animals were observed for 12 weeks, and nerve regeneration was assessed using computerized gait analysis, the grasping test, electrophysiological evaluations and histological quantification of axons, blood vessels and lymphatic vasculature. Here, we provide for the first time a comprehensive analysis of ESWT effects on nerve regeneration in a rat model of median nerve injury. Furthermore, this study is among the first reporting the quantification of lymphatic vessels following peripheral nerve injury and reconstruction in vivo. While we found no significant direct positive effects of ESWT on peripheral nerve regeneration, results following nerve repair with MVCs were significantly inferior to those after ANG repair.}, subject = {Tissue Engineering}, language = {en} } @inproceedings{WidhalmGoeschkaKastner, author = {Widhalm, Dominik and Goeschka, Karl M. and Kastner, Wolfgang}, title = {Node-level indicators of soft faults in wireless sensor networks}, series = {Proceedings of the 40th International Symposium on Reliable Distributed Systems (SRDS 2021), 20-23 September 2021, Chicago, USA}, booktitle = {Proceedings of the 40th International Symposium on Reliable Distributed Systems (SRDS 2021), 20-23 September 2021, Chicago, USA}, publisher = {IEEE}, pages = {13 -- 22}, subject = {wireless sensor network}, language = {en} } @article{Himmelstoss, author = {Himmelstoß, Felix}, title = {Improved positive output voltage super-lift Boost converter}, series = {WSEAS TRANSACTIONS on POWER SYSTEMS}, volume = {2022}, journal = {WSEAS TRANSACTIONS on POWER SYSTEMS}, number = {Vol. 17}, pages = {68 -- 75}, subject = {DC/DC converter}, language = {en} } @article{StrohmeierHofmannJacaketal., author = {Strohmeier, Karin and Hofmann, Martina and Jacak, Jaroslaw and Narzt, Marie-Sophie and Wahlmueller, Marlene and Mairhofer, Mario and Sch{\"a}dl, Barbara and Holnthoner, Wolfgang and Barsch, Martin and Sandhofer, Matthias and Wolbank, Susanne and Priglinger, Eleni}, title = {Multi-Level Analysis of Adipose Tissue Reveals the Relevance of Perivascular Subpopulations and an Increased Endothelial Permeability in Early-Stage Lipedema}, series = {Biomedicines}, volume = {2022}, journal = {Biomedicines}, number = {10(5)}, pages = {1163}, abstract = {Lipedema is a chronic, progressive disease of adipose tissue with unknown etiology. Based on the relevance of the stromal vascular fraction (SVF) cell population in lipedema, we performed a thorough characterization of subcutaneous adipose tissue, SVF isolated thereof and the sorted populations of endothelial cells (EC), pericytes and cultured adipose-derived stromal/stem cells (ASC) of early-stage lipedema patients. We employed histological and gene expression analysis and investigated the endothelial barrier by immunofluorescence and analysis of endothelial permeability in vitro. Although there were no significant differences in histological stainings, we found altered gene expression of factors relevant for local estrogen metabolism (aromatase), preadipocyte commitment (ZNF423) and immune cell infiltration (CD11c) in lipedema on the tissue level, as well as in distinct cellular subpopulations. Machine learning analysis of immunofluorescence images of CD31 and ZO-1 revealed a morphological difference in the cellular junctions of EC cultures derived from healthy and lipedema individuals. Furthermore, the secretome of lipedema-derived SVF cells was sufficient to significantly increase leakiness of healthy human primary EC, which was also reflected by decreased mRNA expression of VE-cadherin. Here, we showed for the first time that the secretome of SVF cells creates an environment that triggers endothelial barrier dysfunction in early-stage lipedema. Moreover, since alterations in gene expression were detected on the cellular and/or tissue level, the choice of sample material is of high importance in elucidating this complex disease.}, subject = {Tissue Engineering}, language = {en} } @article{TriskoFleckKauetal., author = {Trisko, Johanna and Fleck, Johanna and Kau, Silvio and Oesterreicher, Johannes and Holnthoner, Wolfgang}, title = {Lymphatic and Blood Endothelial Extracellular Vesicles: A Story Yet to Be Written}, series = {Life}, volume = {2022}, journal = {Life}, number = {12(5)}, pages = {654}, abstract = {Extracellular vesicles (EVs), such as exosomes, microvesicles, and apoptotic bodies, are cell-derived, lipid bilayer-enclosed particles mediating intercellular communication and are therefore vital for transmitting a plethora of biological signals. The vascular endothelium substantially contributes to the circulating particulate secretome, targeting important signaling pathways that affect blood cells and regulate adaptation and plasticity of endothelial cells in a paracrine manner. Different molecular signatures and functional properties of endothelial cells reflect their heterogeneity among different vascular beds and drive current research to understand varying physiological and pathological effects of blood and lymphatic endothelial EVs. Endothelial EVs have been linked to the development and progression of various vascular diseases, thus having the potential to serve as biomarkers and clinical treatment targets. This review aims to provide a brief overview of the human vasculature, the biology of extracellular vesicles, and the current knowledge of endothelium-derived EVs, including their potential role as biomarkers in disease development.}, subject = {Tissue Engineering}, language = {en} } @article{SayerZandriniMarkovicetal., author = {Sayer, Simon and Zandrini, Tommaso and Markovic, Marica and Van Hoorick, Jasper and Van Vlierberghe, Sandra and Baudis, Stefan and Holnthoner, Wolfgang and Ovsianikov, Aleksandr}, title = {Guiding cell migration in 3D with high-resolution photografting}, series = {Scientific Reports}, volume = {2022}, journal = {Scientific Reports}, number = {12(1), 10196}, pages = {8626}, abstract = {Multi-photon lithography (MPL) has proven to be a suitable tool to precisely control the microenvironment of cells in terms of the biochemical and biophysical properties of the hydrogel matrix. In this work, we present a novel method, based on multi-photon photografting of 4,4′-diazido-2,2′-stilbenedisulfonic acid (DSSA), and its capabilities to induce cell alignment, directional cell migration and endothelial sprouting in a gelatin-based hydrogel matrix. DSSA-photografting allows for the fabrication of complex patterns at a high-resolution and is a biocompatible, universally applicable and straightforward process that is comparably fast. We have demonstrated the preferential orientation of human adipose-derived stem cells (hASCs) in response to a photografted pattern. Co-culture spheroids of hASCs and human umbilical vein endothelial cells (HUVECs) have been utilized to study the directional migration of hASCs into the modified regions. Subsequently, we have highlighted the dependence of endothelial sprouting on the presence of hASCs and demonstrated the potential of photografting to control the direction of the sprouts. MPL-induced DSSA-photografting has been established as a promising method to selectively alter the microenvironment of cells.}, subject = {Tissue Engineering}, language = {en} } @inproceedings{HimmelstossJungmayer, author = {Himmelstoß, Felix and Jungmayer, Michael}, title = {A Family of Modified Converters with Limited Duty Cycle}, series = {Proceedings of the 2021 International Aegean Conference on Electrical Machines and Power Electronics (ACEMP) \& 2021 International Conference on Optimization of Electrical and Electronic Equipment (OPTIM), 2.-3. September 2021, Brasov, Rumania}, booktitle = {Proceedings of the 2021 International Aegean Conference on Electrical Machines and Power Electronics (ACEMP) \& 2021 International Conference on Optimization of Electrical and Electronic Equipment (OPTIM), 2.-3. September 2021, Brasov, Rumania}, publisher = {IEEE}, doi = {https://doi.org/10.1109/OPTIM-ACEMP50812.2021.9590064}, pages = {246 -- 253}, subject = {modified converters}, language = {en} } @article{WidhalmGoeschkaKastner, author = {Widhalm, Dominik and Goeschka, Karl M. and Kastner, Wolfgang}, title = {An open-source wireless sensor node platform with active node-level reliability for monitoring applications}, series = {Sensors}, volume = {2021}, journal = {Sensors}, number = {Volume 21, Issue 22, Article-No. 7613}, subject = {sensor node}, language = {en} } @article{Himmelstoss, author = {Himmelstoß, Felix}, title = {Virtual Laboratory: Switching of A Nearly Resistive Load}, series = {International Journal of Education and Learning Systems}, volume = {2021}, journal = {International Journal of Education and Learning Systems}, number = {Vol. 6}, pages = {13 -- 19}, subject = {virtual laboratory}, language = {en} } @article{HromadaHartmannOesterreicheretal., author = {Hromada, Carina and Hartmann, Jaana and Oesterreicher, Johannes and Stoiber, Anton and Daerr, Anna and Sch{\"a}dl, Barbara and Priglinger, Eleni and Teuschl-Woller, Andreas H. and Holnthoner, Wolfgang and Heinzel, Johannes Christoph and Hercher, David}, title = {Occurrence of Lymphangiogenesis in Peripheral Nerve Autografts Contrasts Schwann Cell-Induced Apoptosis of Lymphatic Endothelial Cells In Vitro}, series = {Biomolecules}, volume = {2022}, journal = {Biomolecules}, number = {12, 6}, pages = {820}, abstract = {Peripheral nerve injuries pose a major clinical concern world-wide, and functional recovery after segmental peripheral nerve injury is often unsatisfactory, even in cases of autografting. Although it is well established that angiogenesis plays a pivotal role during nerve regeneration, the influence of lymphangiogenesis is strongly under-investigated. In this study, we analyzed the presence of lymphatic vasculature in healthy and regenerated murine peripheral nerves, revealing that nerve autografts contained increased numbers of lymphatic vessels after segmental damage. This led us to elucidate the interaction between lymphatic endothelial cells (LECs) and Schwann cells (SCs) in vitro. We show that SC and LEC secretomes did not influence the respective other cell types' migration and proliferation in 2D scratch assay experiments. Furthermore, we successfully created lymphatic microvascular structures in SC-embedded 3D fibrin hydrogels, in the presence of supporting cells; whereas SCs seemed to exert anti-lymphangiogenic effects when cultured with LECs alone. Here, we describe, for the first time, increased lymphangiogenesis after peripheral nerve injury and repair. Furthermore, our findings indicate a potential lymph-repellent property of SCs, thereby providing a possible explanation for the lack of lymphatic vessels in the healthy endoneurium. Our results highlight the importance of elucidating the molecular mechanisms of SC-LEC interaction.}, subject = {Tissue Engineering}, language = {en} } @article{LauerPrahmThieletal., author = {Lauer, Henrik and Prahm, Cosima and Thiel, Johannes Tobias and Kolbenschlag, Jonas and Daigeler, Adrien and Hercher, David and Heinzel, Johannes Christoph}, title = {The Grasping Test Revisited: A Systematic Review of Functional Recovery in Rat Models of Median Nerve Injury}, series = {Biomedicines}, volume = {2022}, journal = {Biomedicines}, number = {10(8)}, pages = {1878}, abstract = {The rat median nerve model is a well-established and frequently used model for peripheral nerve injury and repair. The grasping test is the gold-standard to evaluate functional recovery in this model. However, no comprehensive review exists to summarize the course of functional recovery in regard to the lesion type. According to PRISMA-guidelines, research was performed, including the databases PubMed and Web of Science. Groups were: (1) crush injury, (2) transection with end-to-end or with (3) end-to-side coaptation and (4) isogenic or acellular allogenic grafting. Total and respective number, as well as rat strain, type of nerve defect, length of isogenic or acellular allogenic allografts, time at first signs of motor recovery (FSR) and maximal recovery grasping strength (MRGS), were evaluated. In total, 47 articles met the inclusion criteria. Group I showed earliest signs of motor recovery. Slow recovery was observable in group III and in graft length above 25 mm. Isografts recovered faster compared to other grafts. The onset and course of recovery is heavily dependent from the type of nerve injury. The grasping test should be used complementary in addition to other volitional and non-volitional tests. Repetitive examinations should be planned carefully to optimize assessment of valid and reliable data.}, subject = {Tissue Engineering}, language = {en} } @phdthesis{Widhalm, author = {Widhalm, Dominik}, title = {Sensor Node Fault Detection in Wireless Sensor Networks: An Immune-inspired Approach}, school = {Fachhochschule Technikum Wien}, subject = {fault detection}, language = {en} } @inproceedings{WidhalmGoeschkaKastner, author = {Widhalm, Dominik and Goeschka, Karl M. and Kastner, Wolfgang}, title = {Is Arduino a suitable platform for sensor nodes?}, series = {Proceedings of the 47th Annual Conference of the IEEE Industrial Electronics Society (IECON 2021), 13-16 October 2021, Toronto, Canada}, booktitle = {Proceedings of the 47th Annual Conference of the IEEE Industrial Electronics Society (IECON 2021), 13-16 October 2021, Toronto, Canada}, publisher = {IEEE}, doi = {doi: 10.1109/IECON48115.2021.9589479}, pages = {6}, subject = {Arduino}, language = {en} } @article{HimmelstossEdelmoser, author = {Himmelstoß, Felix and Edelmoser, Karl}, title = {Virtual three-phase laboratory exercise during pandemic situation}, series = {WSEAS TRANSACTIONS on ADVANCES in ENGINEERING EDUCATION}, volume = {2022}, journal = {WSEAS TRANSACTIONS on ADVANCES in ENGINEERING EDUCATION}, pages = {6}, subject = {virtual laboratory}, language = {en} } @inproceedings{HimmelstossVotzi, author = {Himmelstoß, Felix and Votzi, Helmut}, title = {Modified d(2-d)/(1-d)2-Converter}, series = {Proceedings of the Power Conversion and Intelligent Motion Conference (PCIM) 2022, 10-12 May, 2022 Nurenberg, Germany}, booktitle = {Proceedings of the Power Conversion and Intelligent Motion Conference (PCIM) 2022, 10-12 May, 2022 Nurenberg, Germany}, doi = {doi: 10.30420/565822200}, pages = {1446 -- 1453}, subject = {DC/DC converter}, language = {en} } @article{YalcinHimmelstoss, author = {Yalcin, Faruk and Himmelstoß, Felix}, title = {Single-phase Boost-type Active Tracking AC-AC Voltage Regulator with an Improved Hybrid Control Technique}, series = {Duzce University Journal of Science and Technology}, volume = {2022}, journal = {Duzce University Journal of Science and Technology}, number = {10, issue 1}, pages = {139 -- 153}, subject = {Boost converter}, language = {en} } @article{WoeberMehnenSykaceketal., author = {W{\"o}ber, Wilfried and Mehnen, Lars and Sykacek, Peter and Meimberg, Harald}, title = {Investigating Explanatory Factors of Machine Learning Models for Plant Classification}, series = {Plants}, volume = {2021}, journal = {Plants}, number = {10(12):2674}, pages = {20}, abstract = {Recent progress in machine learning and deep learning has enabled the implementation of plant and crop detection using systematic inspection of the leaf shapes and other morphological characters for identification systems for precision farming. However, the models used for this approach tend to become black-box models, in the sense that it is difficult to trace characters that are the base for the classification. The interpretability is therefore limited and the explanatory factors may not be based on reasonable visible characters. We investigate the explanatory factors of recent machine learning and deep learning models for plant classification tasks. Based on a Daucus carota and a Beta vulgaris image data set, we implement plant classification models and compare those models by their predictive performance as well as explainability. For comparison we implemented a feed forward convolutional neuronal network as a default model. To evaluate the performance, we trained an unsupervised Bayesian Gaussian process latent variable model as well as a convolutional autoencoder for feature extraction and rely on a support vector machine for classification. The explanatory factors of all models were extracted and analyzed. The experiments show, that feed forward convolutional neuronal networks (98.24\% and 96.10\% mean accuracy) outperforms the Bayesian Gaussian process latent variable pipeline (92.08\% and 94.31\% mean accuracy) as well as the convolutional autoenceoder pipeline (92.38\% and 93.28\% mean accuracy) based approaches in terms of classification accuracy, even though not significant for Beta vulgaris images. Additionally, we found that the neuronal network used biological uninterpretable image regions for the plant classification task. In contrast to that, the unsupervised learning models rely on explainable visual characters. We conclude that supervised convolutional neuronal networks must be used carefully to ensure biological interpretability. We recommend unsupervised machine learning, careful feature investigation, and statistical feature analysis for biological applications. View Full-Text Keywords: deep learning; machine learning; plant leaf morphometrics; explainable AI}, subject = {deep learning}, language = {en} } @article{RothbauerByrneSchobesbergeretal., author = {Rothbauer, Mario and Byrne, Ruth A. and Schobesberger, Silvia and Olmos Calvo, Isabel and Fischer, Anita and Reihs, Eva I. and Spitz, Sarah and Bachmann, Barbara and Sevelda, Florian and Holinka, Johannes and Holnthoner, Wolfgang and Redl, Heinz and Toegel, Stefan and Windhager, Reinhard and Kiener, Hans P. and Ertl, Peter}, title = {Establishment of a human three-dimensional chip-based chondro-synovial coculture joint model for reciprocal cross talk studies in arthritis research}, series = {Lab on a Chip}, volume = {2021}, journal = {Lab on a Chip}, number = {21}, pages = {4128 -- 4143}, abstract = {Rheumatoid arthritis is characterised by a progressive, intermittent inflammation at the synovial membrane, which ultimately leads to the destruction of the synovial joint. The synovial membrane as the joint capsule's inner layer is lined with fibroblast-like synoviocytes that are the key player supporting persistent arthritis leading to bone erosion and cartilage destruction. While microfluidic models that model molecular aspects of bone erosion between bone-derived cells and synoviocytes have been established, RA's synovial-chondral axis has not yet been realised using a microfluidic 3D model based on human patient in vitro cultures. Consequently, we established a chip-based three-dimensional tissue coculture model that simulates the reciprocal cross talk between individual synovial and chondral organoids. When co-cultivated with synovial organoids, we could demonstrate that chondral organoids induce a higher degree of cartilage physiology and architecture and show differential cytokine response compared to their respective monocultures highlighting the importance of reciprocal tissue-level cross talk in the modelling of arthritic diseases.}, subject = {Tissue Engineering}, language = {en} } @article{YalcinHimmelstoss, author = {Yalcin, Faruk and Himmelstoß, Felix}, title = {Three-phase Active Tracking AC-AC Voltage Regulator based on Buck Converter with an Efficient Hybrid Control Technique}, series = {D{\"u}zce University Journal of Science \& Technology}, volume = {2022}, journal = {D{\"u}zce University Journal of Science \& Technology}, number = {10}, pages = {537 -- 554}, subject = {buck converter}, language = {en} } @inproceedings{DziechWassermannWindischetal., author = {Dziech, Andrzej and Wassermann, Jakob and Windisch, Michael and Baran, Remigiusz and Zeja, Andrzej and Bogacki, Piotr}, title = {A New Approach to Enhance Learning Data Sets for Object Classification}, series = {Proceedings of the International Conference on Circuits, Systems, Communications and Computers, Crete, Greece, July 19-22, 2022}, booktitle = {Proceedings of the International Conference on Circuits, Systems, Communications and Computers, Crete, Greece, July 19-22, 2022}, doi = {https://doi.org/10.1109/CSCC55931.2022.00024}, subject = {poor dataset quality}, language = {en} } @inproceedings{FibichHorauerObermaisser, author = {Fibich, Christian and Horauer, Martin and Obermaisser, Roman}, title = {Characterization of Interconnect Fault Effects in SRAM-based FPGAs}, series = {Proceedings of the 26th International Symposium on Design and Diagnostics of Electronic Circuits and Systems (DDECS 2023), 3-5 May 2023, Tallinn, Estonia}, booktitle = {Proceedings of the 26th International Symposium on Design and Diagnostics of Electronic Circuits and Systems (DDECS 2023), 3-5 May 2023, Tallinn, Estonia}, doi = {https://doi.org/10.1109/DDECS57882.2023.10139343}, pages = {65 -- 68}, subject = {Soft Errors}, language = {en} } @inproceedings{VeiglKlausAigneretal., author = {Veigl, Christoph and Klaus, Benjamin and Aigner, Benjamin and Wagner, Manuel}, title = {Universal Access Panel: A Novel Approach for Accessible Smart Homes and IoT}, series = {Computers Helping People with Special Needs / Proceedings of the 18th International Conference ICCHP-AAATE 2022, July 11-15, 2022, Lecco, Italy}, booktitle = {Computers Helping People with Special Needs / Proceedings of the 18th International Conference ICCHP-AAATE 2022, July 11-15, 2022, Lecco, Italy}, doi = {https://doi.org/10.1007/978-3-031-08645-8_18}, pages = {148 -- 158}, abstract = {Although various standards and guidelines for accessible design exist, many modern digital devices lack even basic accessibility features. In particular, touchscreens without haptic feedback and a highly complex menu navigation impose serious hurdles for many people - especially for people with disabilities and elderly persons. In this work, we present the Universal Access Panel (UAP) for enabling barrier-free access to home appliances and IoT devices. The system offers a novel, radically simple, multimodal user interface consisting of just a few interaction elements for accessing dedicated functions of the connected home. Using established APIs and communication protocols such as HomeConnect or OpenHab, various domestic appliances, consumer products and smart home devices can be controlled from a single, multimodal interaction console. The system has been designed in cooperation with visually impaired accessibility experts and a user study was conducted with people from the target group. The results show a high overall usability of the prototype.}, subject = {Home Appliances}, language = {en} } @article{HendersonSlingersPedrottietal., author = {Henderson, Ben and Slingers, Gitte and Pedrotti, Michele and Pugliese, Giovanni and Malaskova, Michaela and Bryant, Luke and Lomonaco, Tommaso and Ghimenti, Silvia and Moreno, Sergi and Cordell, Rebecca and Harren, Frans J M and Schubert, Jochen and Mayhew, Chris A and Wilde, Michael and Di Francesco, Fabio and Koppen, Gudrun and Beauchamp, Jonathan D and Cristescu, Simona M}, title = {The peppermint breath test benchmark for PTR-MS and SIFT-MS}, series = {Journal of Breath Research}, journal = {Journal of Breath Research}, number = {15}, doi = {https://doi.org/10.1088/1752-7163/ac1fcf}, pages = {Artikelnr. 046005}, abstract = {A major challenge for breath research is the lack of standardization in sampling and analysis. To address this, a test that utilizes a standardized intervention and a defined study protocol has been proposed to explore disparities in breath research across different analytical platforms and to provide benchmark values for comparison. Specifically, the Peppermint Experiment involves the targeted analysis in exhaled breath of volatile constituents of peppermint oil after ingestion of the encapsulated oil. Data from the Peppermint Experiment performed by proton transfer reaction mass spectrometry (PTR-MS) and selected ion flow tube mass spectrometry (SIFT-MS) are presented and discussed herein, including the product ions associated with the key peppermint volatiles, namely limonene, α- and β-pinene, 1,8-cineole, menthol, menthone and menthofuran. The breath washout profiles of these compounds from 65 individuals were collected, comprising datasets from five PTR-MS and two SIFT-MS instruments. The washout profiles of these volatiles were evaluated by comparing the log-fold change over time of the product ion intensities associated with each volatile. Benchmark values were calculated from the lower 95\% confidence interval of the linear time-to-washout regression analysis for all datasets combined. Benchmark washout values from PTR-MS analysis were 353 min for the sum of monoterpenes and 1,8-cineole (identical product ions), 173 min for menthol, 330 min for menthofuran, and 218 min for menthone; from SIFT-MS analysis values were 228 min for the sum of monoterpenes, 281 min for the sum of monoterpenes and 1,8-cineole, and 370 min for menthone plus 1,8-cineole. Large inter- and intra-dataset variations were observed, whereby the latter suggests that biological variability plays a key role in how the compounds are absorbed, metabolized and excreted from the body via breath. This variability seems large compared to the influence of sampling and analytical procedures, but further investigations are recommended to clarify the effects of these factors.}, subject = {standardization}, language = {en} } @misc{FriedrichLakicPraehauseretal., author = {Friedrich, Robin and Lakic, Nevana and Pr{\"a}hauser, Linda and Schweitzer, Karoline and Olscher, Christoph and Monforte Vila, Xavier and Leitner, Rita and Gepp, Barbara}, title = {Effects of Plastic on the Freshwater Snail Biomphalaria Glabrata}, series = {SETAC Europe 32nd Annual Meeting in Copenhagen, Denmark from 15 - 19. May 2022}, journal = {SETAC Europe 32nd Annual Meeting in Copenhagen, Denmark from 15 - 19. May 2022}, subject = {Ecotoxicology}, language = {en} } @inproceedings{Himmelstoss, author = {Himmelstoss, Felix}, title = {Cascaded control of a Buck converter designed and simulated with the help of LTSpice}, series = {6th International European Congress on Interdisciplinary Scientific Research, Aug. 26-27, 2022, Bukarest, Rumania}, booktitle = {6th International European Congress on Interdisciplinary Scientific Research, Aug. 26-27, 2022, Bukarest, Rumania}, pages = {1086 -- 1096}, subject = {education}, language = {en} } @inproceedings{Himmelstoss, author = {Himmelstoß, Felix}, title = {Controller design of a Buck converter with the help of LTSpice}, series = {Proceedings of the International Asian Congress of Contemporary Sciences, 27-29 May, 2022, Van, Turkiye}, booktitle = {Proceedings of the International Asian Congress of Contemporary Sciences, 27-29 May, 2022, Van, Turkiye}, pages = {195 -- 202}, subject = {DC/DC converter}, language = {en} } @inproceedings{AngelOrsolitsGarcia, author = {Angel, Nikolaus and Orsolits, Horst and Garcia, Jose}, title = {Developing an AR Based Tool for Teaching Motion Analysis on Assembly Tasks}, series = {2022 8th International Conference of the Immersive Learning Research Network (iLRN), 2022}, booktitle = {2022 8th International Conference of the Immersive Learning Research Network (iLRN), 2022}, isbn = {978-1-7348-9952-8}, doi = {10.23919/iLRN55037.2022.9815914}, pages = {7}, abstract = {Engineering education courses look into processes, equipment and people in order to prepare students to tackle problems in their careers. In manufacturing industry, it is important to use virtual manufacturing tools to analyse processes. This includes both equipment and people. Assembly operations can involve human operators. Modular arrangements of predetermined time standards MODAPTS is a predetermined motion time system method used to analyse assembly processes. Augmented reality (AR) is increasingly being used for industrial processes as well as in education. AR application have been used for maintenance training as a useful way to overly digital instructions to a trainee whilst being able to look at a real object. This is potential beneficial for education. This paper presents the evaluation of a prototype to test a predetermined time standards model using an AR application. An evaluation was carried out comparing AR-based instructions in tablet and PC monitor and paper-written instructions. The results of evaluating the prototype encourage their use as an educational tool in engineering courses.}, subject = {Augmented Reality}, language = {en} } @misc{Kupka, author = {Kupka, Friedrich}, title = {On the Potential of the Reynolds Stress Approach to Model Convective Overshooting in Grids of Stellar Evolution Models}, doi = {https://doi.org/10.5281/zenodo.5572778}, subject = {Convection}, language = {en} } @article{AshmwePosaRuehrnoessletal., author = {Ashmwe, Mohamed and Posa, Katja and R{\"u}hrn{\"o}ßl, Alexander and Heinzel, Johannes Christoph and Heimel, Patrick and Mock, Michael and Sch{\"a}dl, Barbara and Keibl, Claudia and Couillard-Despres, Sebastien and Redl, Heinz and Mittermayr, Rainer and Hercher, David}, title = {Effects of Extracorporeal Shockwave Therapy on Functional Recovery and Circulating miR-375 and miR-382-5p after Subacute and Chronic Spinal Cord Contusion Injury in Rats}, series = {Biomedicines}, volume = {2022}, journal = {Biomedicines}, number = {10(7)}, doi = {https://doi.org/10.3390/biomedicines10071630}, pages = {1630}, abstract = {Extracorporeal shockwave therapy (ESWT) can stimulate processes to promote regeneration, including cell proliferation and modulation of inflammation. Specific miRNA expression panels have been established to define correlations with regulatory targets within these pathways. This study aims to investigate the influence of low-energy ESWT-applied within the subacute and chronic phase of SCI (spinal cord injury) on recovery in a rat spinal cord contusion model. Outcomes were evaluated by gait analysis, µCT and histological analysis of spinal cords. A panel of serum-derived miRNAs after SCI and after ESWT was investigated to identify injury-, regeneration- and treatment-associated expression patterns. Rats receiving ESWT showed significant improvement in motor function in both a subacute and a chronic experimental setting. This effect was not reflected in changes in morphology, µCT-parameters or histological markers after ESWT. Expression analysis of various miRNAs, however, revealed changes after SCI and ESWT, with increased miR-375, indicating a neuroprotective effect, and decreased miR-382-5p potentially improving neuroplasticity via its regulatory involvement with BDNF. We were able to demonstrate a functional improvement of ESWT-treated animals after SCI in a subacute and chronic setting. Furthermore, the identification of miR-375 and miR-382-5p could potentially provide new targets for therapeutic intervention in future studies.}, subject = {Tissue Engineering}, language = {en} } @article{RomanelliBielerHeimeletal., author = {Romanelli, Pasquale and Bieler, Lara and Heimel, Patrick and Škokić, Siniša and Jakubecova, Dominika and Kreutzer, Christina and Zaunmair, Pia and Smolčić, Tomislav and Benedetti, Bruno and Rohde, Eva and Gimona, Mario and Hercher, David and Dobrivojević Radmilović, Marina and Couillard-Despres, Sebastien}, title = {Enhancing Functional Recovery Through Intralesional Application of Extracellular Vesicles in a Rat Model of Traumatic Spinal Cord Injury}, series = {Front Cell Neurosci}, volume = {15}, journal = {Front Cell Neurosci}, doi = {10.3389/fncel.2021.795008}, abstract = {Local inflammation plays a pivotal role in the process of secondary damage after spinal cord injury. We recently reported that acute intravenous application of extracellular vesicles (EVs) secreted by human umbilical cord mesenchymal stromal cells dampens the induction of inflammatory processes following traumatic spinal cord injury. However, systemic application of EVs is associated with delayed delivery to the site of injury and the necessity for high doses to reach therapeutic levels locally. To resolve these two constraints, we injected EVs directly at the lesion site acutely after spinal cord injury. We report here that intralesional application of EVs resulted in a more robust improvement of motor recovery, assessed with the BBB score and sub-score, as compared to the intravenous delivery. Moreover, the intralesional application was more potent in reducing inflammation and scarring after spinal cord injury than intravenous administration. Hence, the development of EV-based therapy for spinal cord injury should aim at an early application of vesicles close to the lesion.}, subject = {exosomes}, language = {en} } @article{FeichtingerHeimelTangletal., author = {Feichtinger, Xaver and Heimel, Patrick and Tangl, Stefan and Keibl, Claudia and N{\"u}rnberger, Sylvia and Schanda, Jakob Emanuel and Hercher, David and Kocijan, Roland and Redl, Heinz and Grillari, Johannes and Fialka, Christian and Mittermayr, Rainer}, title = {Improved biomechanics in experimental chronic rotator cuff repair after shockwaves is not reflected by bone microarchitecture}, series = {PLoS One}, volume = {17}, journal = {PLoS One}, number = {1}, doi = {10.1371/journal.pone.0262294}, subject = {chronic rotator cuff repair}, language = {en} } @misc{LangerNemecKollmitzeretal., author = {Langer, Sarah and Nemec, Iris and Kollmitzer, Josef and Scherer, Matthias and Martinek, Johannes}, title = {Vergleich des decompositionierten und des {\"u}berlagerten Elektromyogramms zur Analyse der Muskelerm{\"u}dung}, abstract = {Ziel dieser Studie war das {\"u}berlagerte Elektromyogramm (ueEMG) und das decompositionierte (dEMG) auf deren Reliabilit{\"a}t und Aussagekraft zu {\"u}berpr{\"u}fen. Hierf{\"u}r vollzogen zehn gesunde m{\"a}nnliche Probanden zu drei Testzeitpunkten isometrische Erm{\"u}dungsmessungen. Hintergrund Bei der Messung des ueEMG werden die Motor Units Aktionspotentiale (MUAPS) elektrisch {\"u}berlagert. Physiologische Muskelerm{\"u}dung zeigt sich hier unter anderem in der Ver{\"a}nderung des Frequenzspektrums und der Signalamplitude. Letzteres steigt bei Erm{\"u}dung an, wohingegen die mediane Frequenz (MF) sinkt. Eine weitere M{\"o}glichkeit die Muskelerm{\"u}dung mittels Oberfl{\"a}chen-EMG zu ermitteln ist die Anwendung des dEMGs. Dieses erm{\"o}glicht mithilfe einer Mustererkennungssoftware einzelne MUAPS zu erkennen. Studien zeigten, dass aktive Motor Units (MU) bei wiederholten oder anhaltenden submaximalen Kontraktionen als Muskelerm{\"u}dung ihre Feuerungsrate erh{\"o}hen und neue MU rekrutiert werden. Bisher wurden diese Methoden jeweils einzeln betrachtet. Um sicherzustellen welcher Ansatz f{\"u}r klinische Daten geeigneter ist, wurden Datens{\"a}tze zu beiden Methoden gleichzeitig generiert und hinsichtlich ihrer Aussagekraft und Wiederholbarkeit mit statistischen Mitteln verglichen.}, subject = {Elektromyogramm}, language = {de} }