@article{WalaFelleitnerGoll,
  author    = {Wala, Thomas and Felleitner-Goll, Katharina},
  title     = {Digitalisierung in der Weiterbildung. Wie man mit eigenen Online-Kursen ein passives Zusatzeinkommen generieren kann.},
  series = {ASoK},
  journal   = {ASoK},
  number    = {5},
  pages     = {189 -- 191},
  subject      = {Weiterbildung},
  language  = {de}
}
@article{WalaFelleitnerGoll,
  author    = {Wala, Thomas and Felleitner-Goll, Katharina},
  title     = {Technologiemanagement},
  series = {WISU},
  journal   = {WISU},
  number    = {4},
  pages     = {349 -- 350},
  subject      = {Technologiemanagement},
  language  = {de}
}
@article{KierspelKadekBarranetal.,
  author    = {Kierspel, Thomas and Kadek, Alan and Barran, Perdita and Bellina, Bruno and Bijedic, Adi and Brodmerkel, Maxim N. and Commandeur, Jan and Caleman, Carl and Damjanovic, Tomislav and Dawod, Ibrahim and De Santis, Emiliano and Lekkas, Alexandros and Lorenzen, Kristina and L{\´o}pez Morillo, Luis and Mandl, Thomas and Marklund, Erik G. and Papanastasiou, Dimitris and Ramakers, Lennart A. I. and Schweikhard, Lutz and Simke, Florian and Sinelnikova, Anna and Smyrnakis, Athanasios and Timneanu, Nicusor and Uetrecht, Charlotte},
  title     = {Coherent diffractive imaging of proteins and viral capsids: simulating MS SPIDOC},
  series = {Analytical and Bioanalytical Chemistry},
  volume    = {2023},
  journal   = {Analytical and Bioanalytical Chemistry},
  number    = {415},
  doi       = {https://doi.org/10.1007/s00216-023-04658-y},
  pages     = {4209 -- 4220},
  abstract  = {MS SPIDOC is a novel sample delivery system designed for single (isolated) particle imaging at X-ray Free-Electron Lasers that is adaptable towards most large-scale facility beamlines. Biological samples can range from small proteins to MDa particles. Following nano-electrospray ionization, ionic samples can be m/z-filtered and structurally separated before being oriented at the interaction zone. Here, we present the simulation package developed alongside this prototype. The first part describes how the front-to-end ion trajectory simulations have been conducted. Highlighted is a quadrant lens; a simple but efficient device that steers the ion beam within the vicinity of the strong DC orientation field in the interaction zone to ensure spatial overlap with the X-rays. The second part focuses on protein orientation and discusses its potential with respect to diffractive imaging methods. Last, coherent diffractive imaging of prototypical T = 1 and T = 3 norovirus capsids is shown. We use realistic experimental parameters from the SPB/SFX instrument at the European XFEL to demonstrate that low- resolution diffractive imaging data (q < 0.3 nm -1 ) can be collected with only a few X-ray pulses. Such low-resolution data are sufficient to distinguish between both symmetries of the capsids, allowing to probe low abundant species in a beam if MS SPIDOC is used as sample delivery.},
  subject      = {SPI},
  language  = {en}
}
@article{HanetsederLevstekTeuschlWolleretal.,
  author    = {Hanetseder, Dominik and Levstek, Tina and Teuschl-Woller, Andreas and Frank, Julia Katharina and Schaedl, Barbara and Redl, Heinz and Marolt Presen, Darja},
  title     = {Engineering of extracellular matrix from human iPSC-mesenchymal progenitors to enhance osteogenic capacity of human bone marrow stromal cells independent of their age},
  series = {Front Bioeng Biotechnol},
  volume    = {11},
  journal   = {Front Bioeng Biotechnol},
  doi       = {https://doi.org/10.3389/fbioe.2023.1214019},
  abstract  = {Regeneration of bone defects is often limited due to compromised bone tissue physiology. Previous studies suggest that engineered extracellular matrices enhance the regenerative capacity of mesenchymal stromal cells. In this study, we used human-induced pluripotent stem cells, a scalable source of young mesenchymal progenitors (hiPSC-MPs), to generate extracellular matrix (iECM) and test its effects on the osteogenic capacity of human bone-marrow mesenchymal stromal cells (BMSCs). iECM was deposited as a layer on cell culture dishes and into three-dimensional (3D) silk-based spongy scaffolds. After decellularization, iECM maintained inherent structural proteins including collagens, fibronectin and laminin, and contained minimal residual DNA. Young adult and aged BMSCs cultured on the iECM layer in osteogenic medium exhibited a significant increase in proliferation, osteogenic marker expression, and mineralization as compared to tissue culture plastic. With BMSCs from aged donors, matrix mineralization was only detected when cultured on iECM, but not on tissue culture plastic. When cultured in 3D iECM/silk scaffolds, BMSCs exhibited significantly increased osteogenic gene expression levels and bone matrix deposition. iECM layer showed a similar enhancement of aged BMSC proliferation, osteogenic gene expression, and mineralization compared with extracellular matrix layers derived from young adult or aged BMSCs. However, iECM increased osteogenic differentiation and decreased adipocyte formation compared with single protein substrates including collagen and fibronectin. Together, our data suggest that the microenvironment comprised of iECM can enhance the osteogenic activity of BMSCs, providing a bioactive and scalable biomaterial strategy for enhancing bone regeneration in patients with delayed or failed bone healing.},
  subject      = {aging},
  language  = {en}
}
@article{BernhardMaroltPresenLietal.,
  author    = {Bernhard, Jonathan C and Marolt Presen, Darja and Li, Ming and Monforte, Xavier and Ferguson, James and Leinfellner, Gabriele and Heimel, Patrick and Betti, Susanne L and Shu, Sharon and Teuschl-Woller, Andreas H and Tangl, Stefan and Redl, Heinz and Vunjak-Novakovic, Gordana},
  title     = {Effects of Endochondral and Intramembranous Ossification Pathways on Bone Tissue Formation and Vascularization in Human Tissue-Engineered Grafts},
  series = {Cells},
  volume    = {11},
  journal   = {Cells},
  number    = {19:3070},
  doi       = {10.3390/cells11193070},
  abstract  = {Bone grafts can be engineered by differentiating human mesenchymal stromal cells (MSCs) via the endochondral and intramembranous ossification pathways. We evaluated the effects of each pathway on the properties of engineered bone grafts and their capacity to drive bone regeneration. Bone-marrow-derived MSCs were differentiated on silk scaffolds into either hypertrophic chondrocytes (hyper) or osteoblasts (osteo) over 5 weeks of in vitro cultivation, and were implanted subcutaneously for 12 weeks. The pathways' constructs were evaluated over time with respect to gene expression, composition, histomorphology, microstructure, vascularization and biomechanics. Hypertrophic chondrocytes expressed higher levels of osteogenic genes and deposited significantly more bone mineral and proteins than the osteoblasts. Before implantation, the mineral in the hyper group was less mature than that in the osteo group. Following 12 weeks of implantation, the hyper group had increased mineral density but a similar overall mineral composition compared with the osteo group. The hyper group also displayed significantly more blood vessel infiltration than the osteo group. Both groups contained M2 macrophages, indicating bone regeneration. These data suggest that, similar to the body's repair processes, endochondral pathway might be more advantageous when regenerating large defects, whereas intramembranous ossification could be utilized to guide the tissue formation pattern with a scaffold architecture.},
  subject      = {bone tissue engineering},
  language  = {en}
}
@article{GollmannTepekoeylueGraberHirschetal.,
  author    = {Gollmann-Tepek{\"o}yl{\"u}, Can and Graber, Michael and Hirsch, Jakob and Mair, Sophia and Naschberger, Andreas and P{\"o}lzl, Leo and N{\"a}gele, Felix and Kirchmair, Elke and Degenhart, Gerald and Demetz, Egon and Hilbe, Richard and Chen, Hao-Yu and Engert, James C and B{\"o}hm, Anna and Franz, Nadja and Lobenwein, Daniela and Lener, Daniela and Fuchs, Christiane and Weihs, Anna and T{\"o}chterle, Sonja and Vogel, Georg F and Schweiger, Victor and Eder, Jonas and Pietschmann, Peter and Seifert, Markus and Kronenberg, Florian and Coassin, Stefan and Blumer, Michael and Hackl, Hubert and Meyer, Dirk and Feuchtner, Gudrun and Kirchmair, Rudolf and Troppmair, Jakob and Krane, Markus and Weiss, G{\"u}nther and Tsimikas, Sotirios and Thanassoulis, George and Grimm, Michael and Rupp, Bernhard and Huber, Lukas A and Zhang, Shen-Ying and Casanova, Jean-Laurent and Tancevski, Ivan and Holfeld, Johannes},
  title     = {Toll-Like Receptor 3 Mediates Aortic Stenosis Through a Conserved Mechanism of Calcification},
  series = {Circulation},
  volume    = {147},
  journal   = {Circulation},
  number    = {20},
  doi       = {10.1161/CIRCULATIONAHA.122.063481},
  pages     = {1518 -- 1533},
  subject      = {Toll-like receptor 3},
  language  = {en}
}
@article{XuGeppLenggeretal.,
  author    = {Xu, Yingyang and Gepp, Barbara and Lengger, Nina and Yin, Jia and Breiteneder, Heimo},
  title     = {Identification of probable pectinesterase as a major allergen of pollen of the Asian white birch (Betula platyphylla) in northern China},
  series = {Asian Pac J Allergy Immunol},
  journal   = {Asian Pac J Allergy Immunol},
  doi       = {10.12932/AP-100722-1409},
  subject      = {birch pollen allergy},
  language  = {en}
}
@article{AhlbornKupkaWeissetal.,
  author    = {Ahlborn, Felix and Kupka, Friedrich and Weiss, Achim and Flaskamp, Martin},
  title     = {Stellar evolution models with overshooting based on 3-equation non-local theories: II. Main sequence models of A- and B-type stars},
  series = {Astronomy \& Astrophysics},
  journal   = {Astronomy \& Astrophysics},
  number    = {Volume 667},
  doi       = {https://doi.org/10.1051/0004-6361/202243126},
  pages     = {Article Number A97},
  subject      = {convection},
  language  = {en}
}
@article{KupkaAhlbornWeiss,
  author    = {Kupka, Friedrich and Ahlborn, Felix and Weiss, Achim},
  title     = {Stellar evolution models with overshooting based on 3-equation non-local theories: I. Physical basics and the computation of the dissipation rate},
  series = {Astronomy \& Astrophysics},
  journal   = {Astronomy \& Astrophysics},
  number    = {Volume 667},
  doi       = {https://doi.org/10.1051/0004-6361/202243125},
  pages     = {Article Number A96},
  subject      = {convection},
  language  = {en}
}
@article{Huber,
  author    = {Huber, Albert},
  title     = {Quasilocal corrections to Bondi's mass-loss formula and dynamical horizons},
  series = {Physical Review D},
  volume    = {Vol. 108},
  journal   = {Physical Review D},
  number    = {issue 8},
  doi       = {https://doi.org/10.1103/PhysRevD.108.084056},
  subject      = {Bondi´s mass-loss formula},
  language  = {en}
}