@misc{HeherTomaschMaleineretal., author = {Heher, Philipp and Tomasch, Janine and Maleiner, Babette and Redl, Heinz and Fuchs, Christiane}, title = {The Importance of Biomechanical Cues for In Vitro Skeletal Myogenesis}, subject = {In Vitro}, language = {en} } @misc{Tomasch, author = {Tomasch, Janine}, title = {Generation of 3D skeletal muscle-like scaffolds via the application of mechanical stimuli}, subject = {Scaffold}, language = {en} } @inproceedings{NebelSaladoManzanoJustetal., author = {Nebel, Sabrina and Salado Manzano, Cristina and Just, Valentin and Leeb, Christine and Jesenberger, Veronika}, title = {Role of the MEK/ERK pathway in chondrogenic differentiation: Establishment of a protocol for the generation of MEK1-knockout hTERT ASCs and assessment of their differentiation potential}, series = {Proceedings des Forschungsforum 2017 der {\"o}sterreichischen Fachhochschulen}, booktitle = {Proceedings des Forschungsforum 2017 der {\"o}sterreichischen Fachhochschulen}, subject = {Chondrogenesis}, language = {en} } @misc{NebelSaladoManzanoJustetal., author = {Nebel, Sabrina and Salado Manzano, Cristina and Just, Valentin and Leeb, Christine and Jesenberger, Veronika}, title = {Role of the MEK/ERK pathway in chondrogenic differentiation: Establishment of a protocol for the generation of MEK1-knockout hTERT ASCs and assessment of their differentiation potential}, subject = {Chondrogenesis}, language = {en} } @misc{GeppLiousiaMachaceketal., author = {Gepp, Barbara and Liousia, Varvara and Machacek, Thomas and Praher, Daniela and Eisner, Katharina and Limbeck, Sophie and Gamper, Janine and Schwarzl, Elisabeth and Hazod, Till and Landwehr, Renate and Wenger, Charlotte and Olscher, Christoph and Leitner, Rita and R{\"u}nzler, Dominik}, title = {Pelargonic acid - an alternative to glyphosate-based herbicides?}, subject = {Ecotoxicology}, language = {en} } @misc{EisnerGeppSchneggetal., author = {Eisner, Katharina and Gepp, Barbara and Schnegg, Raimund and Dallinger, Reinhard and R{\"u}nzler, Dominik}, title = {Investigation of endocrine effects of sublethal cadmium doses on the reproduction system of the freshwater snail B. glabrata}, subject = {Ecotoxicology}, language = {en} } @article{HackethalMuehlederHoferetal., author = {Hackethal, Johannes and M{\"u}hleder, Severin and Hofer, Alexandra and Schneider, Karl Heinrich and Pr{\"u}ller, Johanna and Hennerbichler, Simone and Redl, Heinz and Teuschl, Andreas}, title = {An Effective Method of Atelocollagen Type 1/3 Isolation from Human Placenta and Its In Vitro Characterization in Two-Dimensional and Three-Dimensional Cell Culture Applications}, series = {Tissue Eng Part C Methods}, volume = {23}, journal = {Tissue Eng Part C Methods}, number = {5}, pages = {274 -- 285}, subject = {Placenta}, language = {en} } @inproceedings{FuchsWeihsSzwarcetal., author = {Fuchs, Christiane and Weihs, Anna and Szwarc, Dorota and Mittermayr, Rainer and R{\"u}nzler, Dominik and Teuschl, Andreas}, title = {Shock wave treatment of muscle (stem) cells - a new implementation for regeneration}, series = {Proceedings of the 20th International Congress of the ISMST}, booktitle = {Proceedings of the 20th International Congress of the ISMST}, subject = {Shockwave treatment}, language = {en} } @article{BerkovitchCohenPeledetal., author = {Berkovitch, Yulia and Cohen, Talia and Peled, Eli and Schmidhammer, Robert and Hildner, Florian and Teuschl, Andreas and Wolbank, Susanne and Yelin, Dvir and Redl, Heinz and Seliktar, Dror}, title = {Hydrogel Composition and Laser Micro-Patterning to Regulate Sciatic Nerve Regeneration}, series = {Journal of Tissue Engineering and Regenerative Medicine}, volume = {12}, journal = {Journal of Tissue Engineering and Regenerative Medicine}, number = {4}, subject = {Micro-Patterning}, language = {en} } @misc{FuchsWeihsSzwarcetal., author = {Fuchs, Christiane and Weihs, Anna and Szwarc, Dorota and Mittermayr, Rainer and R{\"u}nzler, Dominik and Teuschl, Andreas}, title = {Shock wave treatment of muscle (stem) cells - a new implementation for regeneration}, subject = {Shockwave treatment}, language = {en} } @misc{TeuschlWeihsFuchsetal., author = {Teuschl, Andreas and Weihs, Anna and Fuchs, Christiane and Monforte Vila, Xavier}, title = {Silk as a versatile biomaterial for musculoskeletal tissue engineering}, subject = {Silk}, language = {en} } @misc{SzwarcFuchsWeihsetal., author = {Szwarc, Dorota and Fuchs, Christiane and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Molecular mechanisms underlying the potential of shock wave treatment for cardiac therapy}, subject = {Shockwave treatment}, language = {en} } @article{BernhardFergusonRiederetal., author = {Bernhard, Jonathan and Ferguson, James and Rieder, Bernhard and Heimel, Patrick and Nau, Thomas and Tangl, Stefan and Redl, Heinz and Vunjak-Novakovic, Gordana}, title = {Tissue-engineered hypertrophic chondrocyte grafts enhanced long bone repair biomaterials}, series = {Biomaterials}, journal = {Biomaterials}, number = {139}, pages = {202 -- 212}, subject = {Grafting}, language = {en} } @misc{Ruenzler, author = {R{\"u}nzler, Dominik}, title = {Alternatives to Animal Experiment Models: Tracking Zebrafish Larvae and Daphnia}, subject = {Animal Experiments}, language = {en} } @misc{Fuchs, author = {Fuchs, Christiane}, title = {The importance of mechanotransduction in myogenesis}, subject = {Mechanotransduction}, language = {en} } @article{SchneiderLehmannvanOschetal., author = {Schneider, Cornelia and Lehmann, Johannes and van Osch, Gerjo and Hildner, Florian and Teuschl, Andreas and Monforte Vila, Xavier and Miosga, David and Heimel, Patrick and Priglinger, Eleni and Redl, Heinz and Wolbank, Susanne and N{\"u}rnberger, Sylvia}, title = {Systematic Comparison of Protocols for the Preparation of Human Articular Cartilage for Use as Scaffold Material in Cartilage Tissue Engineering}, series = {Tissue Eng Part C Methods}, volume = {22}, journal = {Tissue Eng Part C Methods}, number = {12}, subject = {Cartilage}, language = {en} } @inproceedings{MaleinerHeherTeuschletal., author = {Maleiner, Babette and Heher, Philipp and Teuschl, Andreas and Redl, Heinz and R{\"u}nzler, Dominik and Fuchs, Christiane}, title = {Generation of aligned skeletal muscle-like tissue based on the application of strain to a 3D fibrin scaffold}, series = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, booktitle = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, subject = {Tissue Generation}, language = {en} } @misc{SzwarcFuchsWeihsetal., author = {Szwarc, Dorota and Fuchs, Christiane and Weihs, Anna and Monforte Vila, Xavier and Hanetseder, Dominik and Teuschl, Andreas and R{\"u}nzler, Dominik}, title = {The effect of shock waves on in vitro cartilage development in silk scaffolds}, subject = {Shockwave treatment}, language = {en} } @misc{MaleinerHeherTeuschletal., author = {Maleiner, Babette and Heher, Philipp and Teuschl, Andreas and Redl, Heinz and R{\"u}nzler, Dominik and Fuchs, Christiane}, title = {Generation of aligned skeletal muscle-like tissue based on the application of strain to a 3D fibrin scaffold}, subject = {Tissue Generation}, language = {en} } @misc{TeuschlFuchsWeihsetal., author = {Teuschl, Andreas and Fuchs, Christiane and Weihs, Anna and Heimel, Patrick and R{\"u}nzler, Dominik and Redl, Heinz and Nau, Thomas}, title = {The Silk Road from Textiles to Novel Medical Implants}, subject = {Silk}, language = {en} } @misc{TeuschlHeimelNuernbergeretal., author = {Teuschl, Andreas and Heimel, Patrick and N{\"u}rnberger, Sylvia and Redl, Heinz and Nau, Thomas}, title = {ACL Regeneration using a novel silk fiber based scaffold - Histological Results of a Large Animal Study}, subject = {Tissue Regeneration}, language = {en} } @misc{Teuschl, author = {Teuschl, Andreas}, title = {Silk Processing - from Gels to ACL Replacement}, subject = {Silk}, language = {en} } @inproceedings{FuchsSzwarcWeihsetal., author = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Shock wave treatment of 3D cardiac model systems activates ERK 1/2 signaling pathway and influences cardiomyogenesis}, series = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, booktitle = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, subject = {Shockwave treatment}, language = {en} } @inproceedings{FuchsSzwarcWeihsetal., author = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Shock wave treatment of 3D cardiac model systems activates ERK 1/2 signaling pathway and influences cardiomyogenesis}, series = {Proceedings of LBG Meeting for Health Sciences 2016}, booktitle = {Proceedings of LBG Meeting for Health Sciences 2016}, subject = {Shockwave treatment}, language = {en} } @misc{FuchsSzwarcWeihsetal., author = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Shock wave treatment of 3D cardiac model systems activates ERK 1/2 signaling pathway and influences cardiomyogenesis}, subject = {Shockwave treatment}, language = {en} } @inproceedings{FuchsSzwarcWeihsetal., author = {Fuchs, Christiane and Szwarc, Dorota and Weihs, Anna and R{\"u}nzler, Dominik}, title = {Shock wave treatment positively influences cardiomyogenesis in an energy-dependent manner}, series = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, booktitle = {Proceedings of PACT "Designer Cells go Clinical" Symposium}, subject = {Shockwave treatment}, language = {en} } @misc{Weihs, author = {Weihs, Anna}, title = {Shock wave treatment for in vitro tissue engineering applications}, subject = {Shockwave treatment}, language = {en} } @inproceedings{BasoliChaudryCrucianietal., author = {Basoli, Valentina and Chaudry, Sidrah and Cruciani, Sara and Fuchs, Christiane and Rieger, Sabine and Dungel, Peter and Wolbank, Susanne and Ventura, Carlo and Grillari-Voglauer, Regina and Redl, Heinz and Maioli, Margherita}, title = {Epigenetic and molecular behavious of stem cells exposed to biophysical stimuli: new insights in regenerative medicine}, series = {Proceedings des Seminars zum 40. Jahresjubil{\"a}um der {\"O}sterreichischen Gesellschaft f{\"u}r Chirurgische Forschung}, booktitle = {Proceedings des Seminars zum 40. Jahresjubil{\"a}um der {\"O}sterreichischen Gesellschaft f{\"u}r Chirurgische Forschung}, subject = {Stem Cells}, language = {en} } @misc{BasoliChaudryCrucianietal., author = {Basoli, Valentina and Chaudry, Sidrah and Cruciani, Gabriele and Fuchs, Christiane and Rieger, Sabine and Dungel, Peter and Wolbank, Susanne and Ventura, Carlo and Grillari-Voglauer, Regina and Redl, Heinz and Maioli, Margherita}, title = {Epigenetic and molecular behavious of stem cells exposed to biophysical stimuli: new insights in regenerative medicine}, subject = {Stem Cells}, language = {en} } @misc{Weihs, author = {Weihs, Anna}, title = {Shock wave treatment for in vitro tissue engineering applications}, subject = {Shockwave treatment}, language = {en} } @misc{Weihs, author = {Weihs, Anna}, title = {Mechanotransduction in shock wave treatment}, subject = {Shockwave treatment}, language = {en} } @misc{MandtPichlerMelchioretal., author = {Mandt, Denise and Pichler, Verena and Melchior, Sophie and R{\"u}nzler, Dominik}, title = {Establishment of 2D and 3D cell culture assays using RT-gillW1 cells}, subject = {Cell Culture}, language = {en} } @misc{SalzerRuenzler, author = {Salzer, Elias and R{\"u}nzler, Dominik}, title = {Acute Immobilization Test with Daphnia magna - A Refined Methodology for the Detection of Immobilization}, subject = {Immobilization}, language = {en} } @misc{SalzerRuenzler, author = {Salzer, Elias and R{\"u}nzler, Dominik}, title = {Live or dead is not enough: a large-scale mobility assay with Daphnia magna}, subject = {Mobility Assay}, language = {en} } @misc{Fuchs, author = {Fuchs, Christiane}, title = {A mechanical stimulation strategy for engineering skeletal muscle-like tissue on a strained fibrin scaffold}, subject = {Muscle Tissue}, language = {en} } @misc{Fuchs, author = {Fuchs, Christiane}, title = {The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent}, subject = {In Vitro}, language = {en} } @misc{Fuchs, author = {Fuchs, Christiane}, title = {Mechanotransduction - bioreactors}, subject = {Bioreactors}, language = {en} } @misc{TeuschlSchuhHalbweisetal., author = {Teuschl, Andreas and Schuh, Christina and Halbweis, Robert and Marton, G{\´a}bor and Pajer, Kriszti{\´a}n and Hopf, Rudolf and Mosia, Shorena and R{\"u}nzler, Dominik and N{\´o}gr{\´a}di, Antal and Hausner, Thomas and Redl, Heinz}, title = {Silk fibroin for peripheral nerve regeneration: a novel preparation method improved mechanical characteristics and supports regeneration in rat sciatic nerves}, subject = {Fibroin}, language = {en} } @misc{FuchsWeihsTeuschletal., author = {Fuchs, Christiane and Weihs, Anna and Teuschl, Andreas and Hartinger, Joachim and Slezak, Paul and Mittermayr, Rainer and Redl, Heinz and Junger, Wolfgang and Sitte, Harald and R{\"u}nzler, Dominik}, title = {Shockwave Treatment Enhances Proliferation and Improves Wound Healing via Purinergic Signaling Linked ERK 1/2 Pathways}, subject = {Shockwave treatment}, language = {en} } @misc{FuchsWeihsTeuschletal., author = {Fuchs, Christiane and Weihs, Anna and Teuschl, Andreas and Hartinger, Joachim and Slezak, Paul and Mittermayr, Rainer and Redl, Heinz and Junger, Wolfgang and Sitte, Harald and R{\"u}nzler, Dominik}, title = {Shockwave Treatment Augments Proliferation and Improves Wound Healing via Purinergic Signaling Linked ERK 1/2 Pathways}, subject = {Shockwave treatment}, language = {en} } @misc{TeuschlFuchsFeichtingeretal., author = {Teuschl, Andreas and Fuchs, Christiane and Feichtinger, Georg and Heher, Philipp and Heimel, Patrick and Schuh, Christina and N{\"u}rnberger, Sylvia and Nau, Thomas and R{\"u}nzler, Dominik and Redl, Heinz}, title = {Fibrin or Fibroin - Not only the "o" Makes the Difference}, subject = {Fibrin}, language = {en} } @article{TeuschlBalmayorRedletal., author = {Teuschl, Andreas and Balmayor, Elizabeth and Redl, Heinz and van Griensven, Martijn and Dungel, Peter}, title = {Phototherapy With LED Light Modulates Healing Processes in an In Vitro Scratch Wound-Model Using 3 Different Cell Types}, series = {Dermatologic Surgery}, volume = {41}, journal = {Dermatologic Surgery}, number = {2}, pages = {261 -- 268}, subject = {Phototherapy}, language = {en} } @misc{TeuschlNuernbergerHeimeletal., author = {Teuschl, Andreas and N{\"u}rnberger, Sylvia and Heimel, Patrick and Redl, Heinz and Nau, Thomas}, title = {Regeneration of the Anterior Cruciate Ligament Using a Silk-Fiber Based Scaffold - Histological Results}, subject = {Tissue Regeneration}, language = {en} } @article{NauTeuschl, author = {Nau, Thomas and Teuschl, Andreas}, title = {Regeneration of the anterior cruciate ligament: Current strategies in tissue engineering}, series = {World Journal of Orthopedics}, volume = {6}, journal = {World Journal of Orthopedics}, number = {1}, subject = {Ligament}, language = {en} } @phdthesis{Weihs, author = {Weihs, Anna}, title = {Elucidation of extracorporeal shock wave treatment triggered intracellular processes}, school = {Fachhochschule Technikum Wien}, abstract = {Die Wirkung von Stoßwellen auf den menschlichen K{\"o}rper ist bereits seit Jahrzehnten bekannt. Ihr zerst{\"o}rerisches Potential wird seit den 1980-ern zur Behandlung und Desintegration von Nierensteinen angewendet, wo die Stoßwellentherapie heutzutage die Standardbehandlung darstellt. Der erste unerwartete Effekt der Therapie - die Verdichtung des Beckenkammes - wurde schon damals bei Folgeuntersuchungen von Patienten mit Nierensteinen festgestellt. Die Beobachtung, dass Stoßwellen Effekte auf Knochen hervorrufen, ebnete den Weg f{\"u}r die Anwendung der Stoßwellentherapie in Bereichen abseits der Urologie. Mittlerweile wird die Stoßwellentherapie nicht nur zur Behandlung von Knochenbruchheilungsst{\"o}rungen und Tendinopathien, sondern auch bei Weichteilwundheilungsst{\"o}rungen eingesetzt. Trotz der vielf{\"a}ltigen Anwendungsgebiete ist der zugrunde liegende Wirkungsmechanismus des positiven Effekts der Stoßwellentherapie bis heute noch nicht vollst{\"a}ndig aufgekl{\"a}rt. Die Aktivierung von mechanotransduktiven Signalwegen wurde bereits teilweise in vitro und in vivo gezeigt, jedoch meist bei kn{\"o}chernen Indikationen. Doch auch f{\"u}r die Anwendung der Stoßwellentherapie in der (verz{\"o}gerten) Wundheilung ist die Aufkl{\"a}rung des Wirkungsmechanismus essentiell. Erst dadurch k{\"o}nnte diese nicht- invasive, effiziente und großteils Nebenwirkungs-freie Therapieform auch in diesem Bereich als m{\"o}gliche Standardtherapieform genutzt werden. In dieser Dissertation wurde zuerst ein Set-up zur in vitro Stoßwellenanwendung optimiert. Mithilfe eines Molek{\"u}l-Aufnahme Assays wurden die technischen Parameter f{\"u}r die in vitro Stoßwellenbehandlung festgelegt. Mit diesem in vitro Aufbau sollten daraufhin jene intrazellul{\"a}ren Mechanismen identifiziert werden, die von der Stoßwelle beeinflusst werden. In einem in vivo Modell sollte schlussendlich die Rolle dieser Mechanismen am wundheilungsf{\"o}rdernden Effekt der Stoßwelle gekl{\"a}rt werden. Um m{\"o}glichst universelle Effekte der Stoßwelle auf intrazellul{\"a}re Signalwege zu untersuchen, wurden verschiedenste Zelllinien verwendet. Diese beinhalteten die humane U937 Monozyten Zelllinie, humane Jurkat T-Zellen, die humane MG63 Osteosarcoma Zelllinie, die murine C3H10T1/2 mesenchymale Progenitor Zelllinie sowie prim{\"a}re humane mononukle{\"a}re Zellen des peripheren Blutes. Die in den proliferativen Effekt der Stowellentherapie involvierte Signalkaskade konnte darauffolgend erstmals sowohl in murinen C3H10T1/2 Zellen als auch in humanen Fettstammzellen (adipose tissue-derived stem cells) und in humanen Jurkat T-Zellen detailliert beschrieben werden. Außerdem wurde ATP als entscheidendes Signalmolek{\"u}l identifiziert, welches nach Freisetzung durch Stoßwellenbehandlung mittels purinergem Signaling die Erk1/2 Signalkaskade aktiviert. F{\"u}r die dadurch gesteigerte Proliferation in stoßwellenbehandelten Zellen ist die Erk1/2 Aktivierung essentiell. In einem in vivo Model f{\"u}r gest{\"o}rte Wundheilung in der Ratte wurde die Hypothese zur entscheidenden Rolle des Erk1/2 Signalweges im wundheilungsf{\"o}rdernden Effekt der Stoßwelle best{\"a}tigt. In dieser Dissertation wurde gezeigt, dass die durch purinerges Signaling aktivierte Erk1/2 Signalkaskade eine entscheidende Rolle in der durch Stoßwellentherapie beschleunigten Zellproliferation in vitro und Wundheilung in vivo {\"u}bernimmt. Das damit erweiterte Verst{\"a}ndnis der Wirkungsmechanismen der Stoßwellentherapie kann zur Weiterentwicklung dieser Behandlungsform als zuk{\"u}nftige Standardtherapie bei Wundheilungsst{\"o}rungen, wie z.B. f{\"u}r diabetische oder chronische Wunden, beitragen.}, subject = {Healing}, language = {en} } @article{RosserCalvoSchlageretal., author = {Rosser, Julie and Calvo, Isabel Olmos and Schlager, Magdalena and Purtscher, Michaela and Jenner, Florien and Ertl, Peter}, title = {Recent Advances of Biologically Inspired 3D Microfluidic Hydrogel Cell Culture Systems}, series = {J Cell Biol Cell Metalab}, journal = {J Cell Biol Cell Metalab}, number = {2}, subject = {Hydrogel}, language = {en} } @misc{KrollerKreuzingerRuenzler, author = {Kroller, Theophil and Kreuzinger, Norbert and R{\"u}nzler, Dominik}, title = {Validierung und Anwendung eines zellkultur-basierten Assays f{\"u}r Screening von endokrin wirksamen Stoffen in Abwasser}, subject = {Assay}, language = {de} } @misc{GuillaumeMonforteVila, author = {Guillaume, Olivier and Monforte Vila, Xavier}, title = {Development of a Biodegradable Silk Mesh Suitable for Intra-Operative Fast Cell Seeding}, subject = {Silk}, language = {en} } @misc{HeherFuchsPruelleretal., author = {Heher, Philipp and Fuchs, Christiane and Pr{\"u}ller, Johanna and Maleiner, Babette and Kollmitzer, Josef and R{\"u}nzler, Dominik and Teuschl, Andreas and Wolbank, Susanne and Redl, Heinz}, title = {A bioreactor-based 3D culture system for skeletal muscle engineering in fibrin scaffolds}, subject = {Bioreactors}, language = {en} } @article{BanerjeeNuernbergerHennerbichleretal., author = {Banerjee, Asmita and N{\"u}rnberger, Sylvia and Hennerbichler, Simone and Riedl, Stefan and Schuh, Christina and Hacobian, Ara and Teuschl, Andreas and Eibl, J{\"u}rgen and Redl, Heinz}, title = {In toto differentiation of human amniotic membrane towards the Schwann cell lineage}, series = {227-239}, volume = {15}, journal = {227-239}, number = {2}, subject = {Membrane}, language = {en} } @article{ButaDavidDresseletal., author = {Buta, Christiane and David, Robert and Dressel, Ralf and Emgard, Mia and Fuchs, Christiane and Gross, Ulrike and Healy, Lyn and Hescheler, J{\"u}rgen and Kolar, Roman and Martin, Ulrich and Mikkers, Harald and M{\"u}ller, Franz-Josef and Schneider, Rebekka and Seiler, Andrea and Spielmann, Horst and Weitzer, Georg}, title = {REconsidering pluripotency tests: do we still need teratoma assays?}, series = {Stem Cell Research}, volume = {11}, journal = {Stem Cell Research}, number = {1}, pages = {552 -- 562}, subject = {Assay}, language = {en} } @article{HohlriederTeuschlCichaetal., author = {Hohlrieder, Manfred and Teuschl, Andreas and Cicha, Klaus and van Griensven, Martijn and Redl, Heinz and Stampfl, J{\"u}rgen}, title = {Bioreactor and scaffold design for the mechanical stimulation of anterior cruciate ligament grafts}, series = {Biomedical materials and engineering}, volume = {23}, journal = {Biomedical materials and engineering}, number = {3}, pages = {225 -- 237}, subject = {Bioreactors}, language = {en} } @article{DungelTeuschlBanerjeeetal., author = {Dungel, Peter and Teuschl, Andreas and Banerjee, Asmita and Paier-Pourani, Jamile and Redl, Heinz and Kozlov, Andrey}, title = {Impact of mitochondria on nitrite metabolism in HL-1 cardiomyocytes}, series = {Frontiers in Physiology}, journal = {Frontiers in Physiology}, number = {4}, subject = {Nitrite}, language = {en} } @article{TeuschlNuernbergerRedletal., author = {Teuschl, Andreas and N{\"u}rnberger, Sylvia and Redl, Heinz and Nau, Thomas}, title = {Articular cartilage tissue regeneration: current research strategies and outlook for the future}, series = {European Surgery}, volume = {45}, journal = {European Surgery}, number = {3}, pages = {142 -- 153}, subject = {Tissue Regeneration}, language = {en} } @article{TeuschlvanGriensvenRedl, author = {Teuschl, Andreas and van Griensven, Martijn and Redl, Heinz}, title = {Sericin removal from raw Bombys mori silk scaffolds of high hierarchical order}, series = {Tissue Eng Part C Methods}, journal = {Tissue Eng Part C Methods}, subject = {Scaffold}, language = {en} } @misc{KamravamaneshPflueglLackneretal., author = {Kamravamanesh, Donya and Pfl{\"u}gl, Stefan and Lackner, Maximilian and Herwig, Christoph}, title = {Enhancing PHB Production in Synechocystis sp. PCC 6714 by means of Process Engineering and Multivariate Design of Experiments}, subject = {PHB}, language = {en} } @misc{PurtscherErgirSzwarcetal., author = {Purtscher, Michaela and Ergir, Ece and Szwarc, Dorota and Monforte Vila, Xavier and R{\"u}nzler, Dominik and Huber-Gries, Carina}, title = {A microfluidic-based easy-to-use cardiac tissue model for drug screening applications}, subject = {Tissue Generation}, language = {en} } @misc{PurtscherErgirMonforteVilaetal., author = {Purtscher, Michaela and Ergir, Ece and Monforte Vila, Xavier and Huber-Gries, Carina}, title = {Establishment of an in vitro heart tissue model for pre-clinical screening of therapeutic agents using microfluidic technology}, subject = {Tissue Generation}, language = {en} } @misc{PurtscherErgirSzwarcetal., author = {Purtscher, Michaela and Ergir, Ece and Szwarc, Dorota and Huber-Gries, Carina}, title = {Microfluidic based heart-tissue model for directed development of cardiac specific cell types}, subject = {Heart Tissue}, language = {en} } @misc{Lackner, author = {Lackner, Maximilian}, title = {Cyanobacteria as model organism for PHB production}, subject = {Bacteria}, language = {en} } @misc{LacknerKamravamaneshMarkletal., author = {Lackner, Maximilian and Kamravamanesh, Donya and Markl, Erich and Engelhardt-Nowitzki, Corinna and Herwig, Christoph}, title = {Optimization of process parameters to enhance Polyhydroxyalkanoate accumulation in a unicellular cyanobacterium using multivariate experimental design approach}, subject = {Bacteria}, language = {en} } @article{TeuschlZipperleHuberGriesetal., author = {Teuschl, Andreas and Zipperle, Johannes and Huber-Gries, Carina and Kaplan, David}, title = {Silk fibroin based carrier system for delivery of fibrinogen and thrombin as coagulant supplements}, series = {Journal of Biomedical Materials Research}, volume = {105}, journal = {Journal of Biomedical Materials Research}, number = {3}, subject = {Fibrin}, language = {en} } @misc{KamravamaneshPflueglLackneretal., author = {Kamravamanesh, Donya and Pfl{\"u}gl, Stefan and Lackner, Maximilian and Herwig, Christoph}, title = {Photosynthetic poly-β-hydroxybutyrate accumulation in unicellular cyanobacterium Synechocystis sp. PCC 6714}, subject = {Bacteria}, language = {en} } @inproceedings{LeebLeitnerPichleretal., author = {Leeb, Christine and Leitner, Rita and Pichler, Verena and Huber-Gries, Carina and R{\"u}nzler, Dominik and Jesenberger, Veronika}, title = {Einf{\"u}hrung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich}, series = {Proceedings des Kongresses Problem-Based Learning 2016 PBL - Kompetenzen f{\"o}rdern, Zukunft gestalten}, booktitle = {Proceedings des Kongresses Problem-Based Learning 2016 PBL - Kompetenzen f{\"o}rdern, Zukunft gestalten}, subject = {Life Science}, language = {de} } @article{KamravamaneshPflueglNischkaueretal., author = {Kamravamanesh, Donya and Pfl{\"u}gl, Stefan and Nischkauer, Winfried and Limbeck, Andreas and Lackner, Maximilian and Herwig, Christoph}, title = {Photosynthetic poly-β-hydroxybutyrate accumulation in unicellular cyanobacterium Synechocystis sp. PCC 6714}, series = {AMB Express}, volume = {143}, journal = {AMB Express}, number = {7}, subject = {Bacteria}, language = {en} } @misc{KamravamaneshPflueglLackneretal., author = {Kamravamanesh, Donya and Pfl{\"u}gl, Stefan and Lackner, Maximilian and Herwig, Christoph}, title = {Photosynthetic poly-β-hydroxybutyrate accumulation in unicellular cyanobacterium Synechocystis sp. PCC 6714}, subject = {Bacteria}, language = {en} } @book{LacknerGrabowStadler, author = {Lackner, Maximilian and Grabow, Wilhelm and Stadler, Philipp}, title = {Handbook of Online and Near-real-time Methods in Microbiology}, publisher = {Fachhochschule Technikum Wien}, subject = {Microbiology}, language = {en} } @misc{Lackner, author = {Lackner, Maximilian}, title = {PBAT - A versatile bioplastics}, subject = {Bioplastics}, language = {en} } @misc{MuehlederFuchsBassilioetal., author = {M{\"u}hleder, Severin and Fuchs, Christiane and Bassilio, Jose and Sczwarc, Dorota and Pill, Karoline and Slezak, Paul and Labuda, Krystina and Siehs, Christian and Pr{\"o}ll, Johannes and Priglinger, Eleni and Redl, Heinz and Holnthoner, Wolfgang}, title = {The purinergic receptor P2Y2 modulates endothelial sprouting and angiogenesis}, subject = {Angiogenesis}, language = {en} } @article{BachmannSpitzRothbaueretal., author = {Bachmann, Barbara and Spitz, Sarah and Rothbauer, Mario and Jordan, Christian and Purtscher, Michaela and Zirath, Helene and Schuller, Patrick and Eilenberger, Christoph and Ali, Syed Faheem and M{\"u}hleder, Severin and Priglinger, Eleni and Harasek, Michael and Redl, Heinz and Holnthoner, Wolfgang and Ertl, Peter}, title = {Engineering of three-dimensional pre-vascular networks within fibrin hydrogel constructs by microfluidic control over reciprocal cell signaling}, series = {Biomicrofluidics}, journal = {Biomicrofluidics}, subject = {Microfluidic}, language = {en} } @misc{SchneiderAignerMonforteVilaetal., author = {Schneider, Karl Heinrich and Aigner, Petra and Monforte Vila, Xavier and Holnthoner, Wolfgang and Teuschl, Andreas and Bergmeister, Helga and Redl, Heinz}, title = {Naturally derived acellular small diameter vascular grafts from human placenta for reconstructive surgery}, subject = {Placenta}, language = {en} } @misc{LiousiaSalzerMandtetal., author = {Liousia, Varvara and Salzer, Elias and Mandt, Denise and R{\"u}nzler, Dominik}, title = {The impact of ethanol in vitro and in vivo: a comparative study}, subject = {In Vivo}, language = {en} } @misc{LiousiaRuenzler, author = {Liousia, Varvara and R{\"u}nzler, Dominik}, title = {Stage- and dose-dependent effects of methanol and ethanol on the locomotor activity of zebrafish larvae}, subject = {Locomotor Activity}, language = {en} } @article{KierspelKadekBarranetal., author = {Kierspel, Thomas and Kadek, Alan and Barran, Perdita and Bellina, Bruno and Bijedic, Adi and Brodmerkel, Maxim N. and Commandeur, Jan and Caleman, Carl and Damjanovic, Tomislav and Dawod, Ibrahim and De Santis, Emiliano and Lekkas, Alexandros and Lorenzen, Kristina and L{\´o}pez Morillo, Luis and Mandl, Thomas and Marklund, Erik G. and Papanastasiou, Dimitris and Ramakers, Lennart A. I. and Schweikhard, Lutz and Simke, Florian and Sinelnikova, Anna and Smyrnakis, Athanasios and Timneanu, Nicusor and Uetrecht, Charlotte}, title = {Coherent diffractive imaging of proteins and viral capsids: simulating MS SPIDOC}, series = {Analytical and Bioanalytical Chemistry}, volume = {2023}, journal = {Analytical and Bioanalytical Chemistry}, number = {415}, doi = {https://doi.org/10.1007/s00216-023-04658-y}, pages = {4209 -- 4220}, abstract = {MS SPIDOC is a novel sample delivery system designed for single (isolated) particle imaging at X-ray Free-Electron Lasers that is adaptable towards most large-scale facility beamlines. Biological samples can range from small proteins to MDa particles. Following nano-electrospray ionization, ionic samples can be m/z-filtered and structurally separated before being oriented at the interaction zone. Here, we present the simulation package developed alongside this prototype. The first part describes how the front-to-end ion trajectory simulations have been conducted. Highlighted is a quadrant lens; a simple but efficient device that steers the ion beam within the vicinity of the strong DC orientation field in the interaction zone to ensure spatial overlap with the X-rays. The second part focuses on protein orientation and discusses its potential with respect to diffractive imaging methods. Last, coherent diffractive imaging of prototypical T = 1 and T = 3 norovirus capsids is shown. We use realistic experimental parameters from the SPB/SFX instrument at the European XFEL to demonstrate that low- resolution diffractive imaging data (q < 0.3 nm -1 ) can be collected with only a few X-ray pulses. Such low-resolution data are sufficient to distinguish between both symmetries of the capsids, allowing to probe low abundant species in a beam if MS SPIDOC is used as sample delivery.}, subject = {SPI}, language = {en} }