TY  - JOUR
A1  - Pasteka, Richard
A1  - Forjan, Mathias
A1  - Sauermann, Stefan
A1  - Drauschke, Andreas
T1  - Electro-mechanical Lung Simulator Using Polymer and Organic Human Lung Equivalents for Realistic Breathing Simulation
JF  - Scientific Reports
N2  - Simulation models in respiratory research are increasingly used for medical product development and testing, especially because in-vivo models are coupled with a high degree of complexity and ethical concerns. This work introduces a respiratory simulation system, which is bridging the gap between the complex, real anatomical environment and the safe, cost-effective simulation methods. The presented electro-mechanical lung simulator, xPULM, combines in-silico, ex-vivo and mechanical respiratory approaches by realistically replicating an actively breathing human lung. The reproducibility of sinusoidal breathing simulations with xPULM was verified for selected breathing frequencies (10–18 bpm) and tidal volumes (400–600 ml) physiologically occurring during human breathing at rest. Human lung anatomy was modelled using latex bags and primed porcine lungs. High reproducibility of flow and pressure characteristics was shown by evaluating breathing cycles (nTotal = 3273) with highest standard deviation |3σ| for both, simplified lung equivalents (μV˙ = 23.98 ± 1.04 l/min, μP = −0.78 ± 0.63 hPa) and primed porcine lungs (μV˙ = 18.87 ± 2.49 l/min, μP = −21.13 ± 1.47 hPa). The adaptability of the breathing simulation parameters, coupled with the use of porcine lungs salvaged from a slaughterhouse process, represents an advancement towards anatomically and physiologically realistic modelling of human respiration.
KW  - Breathing Simulation
KW  - Lung Simulator
KW  - Biomedical Engineering
Y1  - 2020
VL  - Vol 9
IS  - No. 1
SP  - Article number: 19778
ER  - 
TY  - JOUR
A1  - Traxler, Lukas
A1  - Bayer, Natascha
A1  - Reutterer, Bernd
A1  - Drauschke, Andreas
A1  - Husinsky, Wolfgang
T1  - Prüfung der optischen Qualität von Intraokularlinsen auf Tolerant gegenüber Fehlplatzierungen im Auge
JF  - Proceedings der Jahrestagung der Österreichischen Gesellschaft für Biomedizinische Technik (ÖGBMT) 2015
KW  - Eye Lens
KW  - Mechanical Eye
KW  - Measurement Error
Y1  - 2018
ER  - 
TY  - JOUR
A1  - Bayer, Natascha
A1  - Hirnschall, Nino
A1  - Traxler, Lukas
A1  - Drauschke, Andreas
A1  - Find, Oliver
T1  - Analysis of customized ocular data and wave front aberrations concerning their deviations from generic eye models
JF  - Proceedings der Dreiländertagung der biomedizinischen Technik (BMT)
KW  - Mechanical Eye
Y1  - 2018
ER  -