TY - GEN A1 - Forjan, Mathias T1 - Reference Architecture and IT Standards for Integrating Medical Devices KW - Electronic Health Records Y1 - 2018 ER - TY - JOUR A1 - Pasteka, Richard A1 - Santos da Costa, Joao Pedro A1 - Barros, Nelson A1 - Kolar, Radim A1 - Forjan, Mathias T1 - Patient–Ventilator Interaction Testing Using the Electromechanical Lung Simulator xPULMTM during V/A-C and PSV Ventilation Mode JF - Applied Sciences N2 - During mechanical ventilation, a disparity between flow, pressure and volume demands of the patient and the assistance delivered by the mechanical ventilator often occurs. This paper introduces an alternative approach of simulating and evaluating patient–ventilator interactions with high fidelity using the electromechanical lung simulator xPULM™. The xPULM™ approximates respiratory activities of a patient during alternating phases of spontaneous breathing and apnea intervals while connected to a mechanical ventilator. Focusing on different triggering events, volume assist-control (V/A-C) and pressure support ventilation (PSV) modes were chosen to test patient–ventilator interactions. In V/A-C mode, a double-triggering was detected every third breathing cycle, leading to an asynchrony index of 16.67%, which is classified as severe. This asynchrony causes a significant increase of peak inspiratory pressure (7.96 ± 6.38 vs. 11.09 ± 0.49 cmH2O, p < 0.01)) and peak expiratory flow (−25.57 ± 8.93 vs. 32.90 ± 0.54 L/min, p < 0.01) when compared to synchronous phases of the breathing simulation. Additionally, events of premature cycling were observed during PSV mode. In this mode, the peak delivered volume during simulated spontaneous breathing phases increased significantly (917.09 ± 45.74 vs. 468.40 ± 31.79 mL, p < 0.01) compared to apnea phases. Various dynamic clinical situations can be approximated using this approach and thereby could help to identify undesired patient–ventilation interactions in the future. Rapidly manufactured ventilator systems could also be tested using this approach. View Full-Text KW - Breathing Simulation KW - Biomedical Engineering KW - Electromechanical lung simulator Y1 - VL - 11 IS - 9 ER - TY - GEN A1 - Frohner, Matthias A1 - Forjan, Mathias T1 - Interoperability in the OR Introducing OR.NET KW - Interoperability KW - Emergency Room KW - Harmonization Y1 - ER - TY - CHAP A1 - Frohner, Matthias A1 - Windisch, Michael A1 - Sauermann, Stefan A1 - Sekora, Jiri A1 - Forjan, Mathias T1 - Organ Telemonitoring in Ex-vivo Nutrition Circulation of Porcine Lungs Using Interoperability Standards T2 - Proceedings of the 12th IFAC/IEEE International Conference on Programmable Devices and Embedded Systems (PDeS 2013) KW - Telemonitoring KW - Lung Simulator KW - Interoperability Y1 - 2018 SP - 335 EP - 340 ER - TY - CHAP A1 - Lenz, Gregor A1 - Frohner, Matthias A1 - Sauermann, Stefan A1 - Forjan, Mathias T1 - LUMOR: An App for Standardized Control and Monitoring of a Porcine Lung and its Nutrient Cycle T2 - Proceedings of eHealth 2014 - Health Informatics Meets Informatics KW - Lung Simulator Y1 - 2018 ER - TY - CHAP A1 - Forjan, Mathias A1 - Frohner, Matthias T1 - Development of the mCM - mobile circulatory module - for ex-vivo physiological tissue for breathing simulation T2 - Abstracts of the 9th World Congress on Alternatives and Animal Use in the Life Sciences (ALTEX Proceedings) 2014 KW - Lung Simulator KW - Breathing Y1 - 2018 SP - 52 EP - 52 ER - TY - GEN A1 - Lenz, Gregor A1 - Frohner, Matthias A1 - Sauermann, Stefan A1 - Forjan, Mathias T1 - LUMOR: An App for Standardized Control and Monitoring of a Porcine Lung and its Nutrient Cycle KW - Lung Simulator Y1 - 2018 ER - TY - CHAP A1 - Urbauer, Philipp A1 - Herzog, Juliane A1 - Pohn, Birgit A1 - Forjan, Mathias A1 - Sauermann, Stefan T1 - Certification Programs for eHealth - Status Quo T2 - Proceedings of eHealth 2014 - Health Informatics Meets Informatics KW - eHealth KW - Education Y1 - 2018 ER - TY - GEN A1 - Forjan, Mathias A1 - Frohner, Matthias T1 - Development of the mCM - mobile circulatory module - for ex-vivo physiological tissue for breathing simulation KW - Lung Simulator KW - Breathing Y1 - 2018 ER - TY - GEN A1 - David, Veronika A1 - Forjan, Mathias A1 - Tkachenko Bril, Andres Igor T1 - Klinische Pilotstudie zur Prüfung der Machbarkeit und Akzeptanz eines Biofeedbacksystems zur Unterstützung der teilbelastenden Mobilisation KW - eHealth Y1 - 2018 ER -