TY  - JOUR
A1  - Huber-Gries, Carina
A1  - Ilk, Nicola
A1  - Rünzler, Dominik
A1  - Egelseer, Eva-Maria
A1  - Weigert, Stefan
A1  - Sleytr, Uwe
T1  - The three S-layer-like homology motifs of the S-layer protein SbpA of Bacillus sphaericus CCM 2177 are not sufficient for binding to the pyruvylated secondary cell wall polymer
JF  - Molecular Microbiology
KW  - Proteins
Y1  - 2018
VL  - 55
IS  - 1
SP  - 197
EP  - 205
ER  - 
TY  - GEN
A1  - Purtscher, Michaela
A1  - Ergir, Ece
A1  - Szwarc, Dorota
A1  - Monforte Vila, Xavier
A1  - Rünzler, Dominik
A1  - Huber-Gries, Carina
T1  - A microfluidic-based easy-to-use cardiac tissue model for drug screening applications
KW  - Tissue Generation
KW  - Drug Screening
KW  - Cardiac
Y1  - 2018
ER  - 
TY  - GEN
A1  - Hromada, Carina
A1  - Tomasch, Janine
A1  - Weihs, Anna
A1  - Rünzler, Dominik
A1  - Teuschl, Andreas
T1  - Engineering of 3D Tissue Constructs Using our Novel MagneTissue Bioreactor as Alternatives to Animal Models
KW  - Bioreactor
KW  - Biomaterials
Y1  - 
ER  - 
TY  - JOUR
A1  - Leeb, Christine
A1  - Leitner, Rita
A1  - Pichler, Verena
A1  - Huber-Gries, Carina
A1  - Rünzler, Dominik
A1  - Jesenberger, Veronika
T1  - Einführung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich
JF  - Zeitschrift für Hochschulentwicklung (ZFHE)
KW  - Life Science
KW  - Problem Based Learning
KW  - Education
Y1  - 2018
VL  - 11
IS  - 3
SP  - 107
EP  - 121
ER  - 
TY  - JOUR
A1  - Rieder, Bernhard
A1  - Weihs, Anna
A1  - Weidinger, Adelheid
A1  - Sczwarc, Dorota
A1  - Nürnberger, Sylvia
A1  - Redl, Heinz
A1  - Rünzler, Dominik
A1  - Huber-Gries, Carina
A1  - Teuschl, Andreas
T1  - Hydrostatic pressure-generated reactive oxygen species induce osteoarthritic conditions in cartilage pellet cultures
JF  - Scientific Reports
KW  - Bioreactor
KW  - Osteoarthritis
KW  - Cartilage
KW  - Reactive oxygen species
Y1  - 
ER  - 
TY  - CHAP
A1  - Huber-Gries, Carina
A1  - Moll, Dieter
A1  - Liu, Jing
A1  - Rünzler, Dominik
A1  - Sára, Margit
A1  - Sleytr, Uwe
T1  - S-layer-streptavidin fusion proteins: Novel Tools in Nanobiotechnology
T2  - 6th Annual Linz Winter Workshop - Book of Abstracts
KW  - Proteins
KW  - Nanobiology
KW  - Nanotechnology
Y1  - 2019
SP  - 11
EP  - 11
ER  - 
TY  - CHAP
A1  - Huber-Gries, Carina
A1  - Liu, Jing
A1  - Egelseer, Eva-Maria
A1  - Rünzler, Dominik
A1  - Sára, Margit
A1  - Sleytr, Uwe
T1  - Application Potential of Bacterial Self-Assembly Systems for Nanobiotechnology
T2  - Nanobionics III (from Molecules to Applications) Book of Abstracts
KW  - Nanotechnology
KW  - Nanobiology
KW  - Bacteria
Y1  - 2018
ER  - 
TY  - JOUR
A1  - Rünzler, Dominik
A1  - Huber-Gries, Carina
A1  - Moll, Dieter
A1  - Sára, Margit
T1  - Biophysical characterization of the entire bacterial surface layer protein SbsB and its two distinct functional domains
JF  - Journal of Biological Chemistry
KW  - Life Sciences
KW  - Protein
Y1  - 2019
IS  - 279(7) / 13.
SP  - 5207
EP  - 5215
ER  - 
TY  - CHAP
A1  - Huber-Gries, Carina
A1  - Moll, Dieter
A1  - Schlegel, Birgit
A1  - Rünzler, Dominik
A1  - Mader, Christoph
A1  - Sára, Margit
A1  - Sleytr, Uwe
T1  - Recombinant S-layer-streptavidin fursion proteins: Functional protein lattices as nanoarrays for biochip development
T2  - Proceedings der 28. Jahrestagung der Österreichischen Gesellschaft für Hygiene, Mikrobiologie und Präventivmedizin, Merano (Italy)
KW  - Proteins
KW  - Biochips
Y1  - 2019
ER  - 
TY  - CHAP
A1  - Leeb, Christine
A1  - Leitner, Rita
A1  - Pichler, Verena
A1  - Huber-Gries, Carina
A1  - Rünzler, Dominik
A1  - Jesenberger, Veronika
T1  - Einführung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich
T2  - Proceedings des Kongresses Problem-Based Learning 2016 PBL - Kompetenzen fördern, Zukunft gestalten
KW  - Life Science
KW  - Problem Based Learning
KW  - Education
Y1  - 2018
ER  - 
TY  - GEN
A1  - Rünzler, Dominik
A1  - Moll, Dieter
A1  - Huber-Gries, Carina
A1  - Sleytr, Uwe
A1  - Sára, Margit
A1  - Köhler, Gottfried
T1  - Characterization of the Functional Domains of Bacterial Surface Layer Proteins
T2  - 5th European Symposium of the Protein Society
KW  - Proteins
Y1  - 2019
ER  - 
TY  - GEN
A1  - Leeb, Christine
A1  - Leitner, Rita
A1  - Pichler, Verena
A1  - Huber-Gries, Carina
A1  - Rünzler, Dominik
A1  - Jesenberger, Veronika
T1  - Einführung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich
KW  - Life Science
KW  - Problem Based Learning
KW  - Education
Y1  - 2018
ER  - 
TY  - GEN
A1  - Rünzler, Dominik
A1  - Huber-Gries, Carina
A1  - Sára, Margit
A1  - Köhler, Gottfried
T1  - Fluorescence-based Equilibrium and Kinetic Studies on Carbohydrate-Protein Binding: Interaction of Bacterial Surface Layer Proteins with their Specific Secondary Cell Wall Polymers
KW  - Fluorescence
KW  - Proteins
KW  - Polymer
Y1  - 2019
ER  - 
TY  - CHAP
A1  - Huber-Gries, Carina
A1  - Moll, Dieter
A1  - Liu, Jing
A1  - Rünzler, Dominik
A1  - Sára, Margit
A1  - Sleytr, Uwe B.
T1  - Chimaeric S-Layers as Nanopatterned Biomaterials for  Applications in Nanobiotechnology
T2  - Poster presentation at the 7th Annual Linz Winter Workshop / Book of Abstracts / Linz
KW  - Biomaterial
KW  - Nanobiotechnology
Y1  - 2019
SP  - 1
EP  - 10
ER  - 
TY  - JOUR
A1  - Priglinger, Eleni
A1  - Schuh, Christina
A1  - Steffenhagen, Carolin
A1  - Wurzer, Christoph
A1  - Maier, Julia
A1  - Nürnberger, Sylvia
A1  - Holnthoner, Wolfgang
A1  - Fuchs, Christiane
A1  - Suessner, Susanne
A1  - Rünzler, Dominik
A1  - Redl, Heinz
A1  - Wolbank, Susanne
T1  - Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy.
JF  - Cytotherapy
N2  - BACKGROUND:

Cell-based therapies with autologous adipose tissue-derived cells have shown great potential in several clinical studies in the last decades. The majority of these studies have been using the stromal vascular fraction (SVF), a heterogeneous mixture of fibroblasts, lymphocytes, monocytes/macrophages, endothelial cells, endothelial progenitor cells, pericytes and adipose-derived stromal/stem cells (ASC) among others. Although possible clinical applications of autologous adipose tissue-derived cells are manifold, they are limited by insufficient uniformity in cell identity and regenerative potency.
METHODS:

In our experimental set-up, low-energy extracorporeal shock wave therapy (ESWT) was performed on freshly obtained human adipose tissue and isolated adipose tissue SVF cells aiming to equalize and enhance stem cell properties and functionality.
RESULTS:

After ESWT on adipose tissue we could achieve higher cellular adenosine triphosphate (ATP) levels compared with ESWT on the isolated SVF as well as the control. ESWT on adipose tissue resulted in a significantly higher expression of single mesenchymal and vascular marker compared with untreated control. Analysis of SVF protein secretome revealed a significant enhancement in insulin-like growth factor (IGF)-1 and placental growth factor (PLGF) after ESWT on adipose tissue.
DISCUSSION:

Summarizing we could show that ESWT on adipose tissue enhanced the cellular ATP content and modified the expression of single mesenchymal and vascular marker, and thus potentially provides a more regenerative cell population. Because the effectiveness of autologous cell therapy is dependent on the therapeutic potency of the patient's cells, this technology might raise the number of patients eligible for autologous cell transplantation.
KW  - Shockwave Therapy
KW  - Tissue Regeneration
KW  - Regenerative Medicine
Y1  - 
SP  - 1079
EP  - 1095
ER  - 
TY  - JOUR
A1  - Cieślik-Boczula, Katarzyna
A1  - Küpcü, Seta
A1  - Rünzler, Dominik
A1  - Koll, Aleksander
A1  - Köhler, Gottfried
T1  - Effects of the phenolic lipid 3-pentadecylphenol on phospholipid bilayer organization
JF  - Journal of Molecular Structure
KW  - Phospholipid Bilayer
Y1  - 2019
IS  - 919(1-3)
SP  - 373
EP  - 380
ER  - 
TY  - CHAP
A1  - Knebl, Gerald
A1  - Morton, Tatjana J.
A1  - Redl, Heinz
A1  - Rünzler, Dominik
T1  - Mechanical stimulation of cells in 3-dimensional fibrin constructs using a bioreactor
T2  - 3. Forschungsforum der österreichischen Fachhochschulen / Fachhochschule Kärnten
KW  - Cells
KW  - Bioreactor
Y1  - 2019
SP  - 492
EP  - 493
ER  - 
TY  - JOUR
A1  - Schneider, Karl Heinrich
A1  - Aigner, Petra
A1  - Holnthoner, Wolfgang
A1  - Monforte Vila, Xavier
A1  - Nürnberger, Sylvia
A1  - Rünzler, Dominik
A1  - Redl, Heinz
A1  - Teuschl, Andreas
T1  - Decellularized human placenta chorion matrix as a favorable source of small-diameter vascular grafts
JF  - Acta Biomaterialia
KW  - Grafting
KW  - Tissue Engineering
Y1  - 2018
ER  - 
TY  - JOUR
A1  - Rohringer, Sabrina
A1  - Holnthoner, Wolfgang
A1  - Hackl, Matthias
A1  - Weihs, Anna
A1  - Rünzler, Dominik
A1  - Skalicky, Susanna
A1  - Karbiener, Michael
A1  - Scheideler, Marcel
A1  - Pröll, Johannes
A1  - Gabriel, Christian
A1  - Schweighofer, Bernhard
A1  - Gröger, Marion
A1  - Spittler, Andreas
A1  - Grillari, Johannes
A1  - Redl, Heinz
T1  - Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells.
JF  - PLoS one
KW  - Shockwave
Y1  - 
ER  - 
TY  - GEN
A1  - Liousia, Varvara
A1  - Salzer, Elias
A1  - Mandt, Denise
A1  - Rünzler, Dominik
T1  - The impact of ethanol in vitro and in vivo: a comparative study
KW  - In Vivo
KW  - In Vitro
KW  - Ethanol
Y1  - 2018
ER  -