TY - GEN A1 - Rünzler, Dominik A1 - Moll, Dieter A1 - Huber-Gries, Carina A1 - Sleytr, Uwe A1 - Sára, Margit A1 - Köhler, Gottfried T1 - Characterization of the Functional Domains of Bacterial Surface Layer Proteins T2 - 5th European Symposium of the Protein Society KW - Proteins Y1 - 2019 ER - TY - GEN A1 - Leeb, Christine A1 - Leitner, Rita A1 - Pichler, Verena A1 - Huber-Gries, Carina A1 - Rünzler, Dominik A1 - Jesenberger, Veronika T1 - Einführung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich KW - Life Science KW - Problem Based Learning KW - Education Y1 - 2018 ER - TY - GEN A1 - Rünzler, Dominik A1 - Huber-Gries, Carina A1 - Sára, Margit A1 - Köhler, Gottfried T1 - Fluorescence-based Equilibrium and Kinetic Studies on Carbohydrate-Protein Binding: Interaction of Bacterial Surface Layer Proteins with their Specific Secondary Cell Wall Polymers KW - Fluorescence KW - Proteins KW - Polymer Y1 - 2019 ER - TY - CHAP A1 - Huber-Gries, Carina A1 - Moll, Dieter A1 - Liu, Jing A1 - Rünzler, Dominik A1 - Sára, Margit A1 - Sleytr, Uwe B. T1 - Chimaeric S-Layers as Nanopatterned Biomaterials for Applications in Nanobiotechnology T2 - Poster presentation at the 7th Annual Linz Winter Workshop / Book of Abstracts / Linz KW - Biomaterial KW - Nanobiotechnology Y1 - 2019 SP - 1 EP - 10 ER - TY - JOUR A1 - Priglinger, Eleni A1 - Schuh, Christina A1 - Steffenhagen, Carolin A1 - Wurzer, Christoph A1 - Maier, Julia A1 - Nürnberger, Sylvia A1 - Holnthoner, Wolfgang A1 - Fuchs, Christiane A1 - Suessner, Susanne A1 - Rünzler, Dominik A1 - Redl, Heinz A1 - Wolbank, Susanne T1 - Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy. JF - Cytotherapy N2 - BACKGROUND: Cell-based therapies with autologous adipose tissue-derived cells have shown great potential in several clinical studies in the last decades. The majority of these studies have been using the stromal vascular fraction (SVF), a heterogeneous mixture of fibroblasts, lymphocytes, monocytes/macrophages, endothelial cells, endothelial progenitor cells, pericytes and adipose-derived stromal/stem cells (ASC) among others. Although possible clinical applications of autologous adipose tissue-derived cells are manifold, they are limited by insufficient uniformity in cell identity and regenerative potency. METHODS: In our experimental set-up, low-energy extracorporeal shock wave therapy (ESWT) was performed on freshly obtained human adipose tissue and isolated adipose tissue SVF cells aiming to equalize and enhance stem cell properties and functionality. RESULTS: After ESWT on adipose tissue we could achieve higher cellular adenosine triphosphate (ATP) levels compared with ESWT on the isolated SVF as well as the control. ESWT on adipose tissue resulted in a significantly higher expression of single mesenchymal and vascular marker compared with untreated control. Analysis of SVF protein secretome revealed a significant enhancement in insulin-like growth factor (IGF)-1 and placental growth factor (PLGF) after ESWT on adipose tissue. DISCUSSION: Summarizing we could show that ESWT on adipose tissue enhanced the cellular ATP content and modified the expression of single mesenchymal and vascular marker, and thus potentially provides a more regenerative cell population. Because the effectiveness of autologous cell therapy is dependent on the therapeutic potency of the patient's cells, this technology might raise the number of patients eligible for autologous cell transplantation. KW - Shockwave Therapy KW - Tissue Regeneration KW - Regenerative Medicine Y1 - SP - 1079 EP - 1095 ER - TY - JOUR A1 - Cieślik-Boczula, Katarzyna A1 - Küpcü, Seta A1 - Rünzler, Dominik A1 - Koll, Aleksander A1 - Köhler, Gottfried T1 - Effects of the phenolic lipid 3-pentadecylphenol on phospholipid bilayer organization JF - Journal of Molecular Structure KW - Phospholipid Bilayer Y1 - 2019 IS - 919(1-3) SP - 373 EP - 380 ER - TY - CHAP A1 - Knebl, Gerald A1 - Morton, Tatjana J. A1 - Redl, Heinz A1 - Rünzler, Dominik T1 - Mechanical stimulation of cells in 3-dimensional fibrin constructs using a bioreactor T2 - 3. Forschungsforum der österreichischen Fachhochschulen / Fachhochschule Kärnten KW - Cells KW - Bioreactor Y1 - 2019 SP - 492 EP - 493 ER - TY - JOUR A1 - Schneider, Karl Heinrich A1 - Aigner, Petra A1 - Holnthoner, Wolfgang A1 - Monforte Vila, Xavier A1 - Nürnberger, Sylvia A1 - Rünzler, Dominik A1 - Redl, Heinz A1 - Teuschl, Andreas T1 - Decellularized human placenta chorion matrix as a favorable source of small-diameter vascular grafts JF - Acta Biomaterialia KW - Grafting KW - Tissue Engineering Y1 - 2018 ER - TY - JOUR A1 - Rohringer, Sabrina A1 - Holnthoner, Wolfgang A1 - Hackl, Matthias A1 - Weihs, Anna A1 - Rünzler, Dominik A1 - Skalicky, Susanna A1 - Karbiener, Michael A1 - Scheideler, Marcel A1 - Pröll, Johannes A1 - Gabriel, Christian A1 - Schweighofer, Bernhard A1 - Gröger, Marion A1 - Spittler, Andreas A1 - Grillari, Johannes A1 - Redl, Heinz T1 - Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells. JF - PLoS one KW - Shockwave Y1 - ER - TY - GEN A1 - Liousia, Varvara A1 - Salzer, Elias A1 - Mandt, Denise A1 - Rünzler, Dominik T1 - The impact of ethanol in vitro and in vivo: a comparative study KW - In Vivo KW - In Vitro KW - Ethanol Y1 - 2018 ER - TY - GEN A1 - Liousia, Varvara A1 - Rünzler, Dominik T1 - Stage- and dose-dependent effects of methanol and ethanol on the locomotor activity of zebrafish larvae KW - Locomotor Activity KW - Zebrafish Y1 - 2018 ER -