TY  - JOUR
A1  - Weihs, Anna
A1  - Junger, Wolfgang
A1  - Schaden, Wolfgang
A1  - Sitte, Harald
A1  - Rünzler, Dominik
T1  - Extracorporeal shockwave treatment induced extracellular ATP release - a potential mechanism to activate wound healing
JF  - Journal of Tissue Engineering and Regenerative Medicine
KW  - Shockwave treatment
KW  - Healing Processes
Y1  - 2018
VL  - 1
IS  - 6
SP  - 381
EP  - 381
ER  - 
TY  - JOUR
A1  - Rünzler, Dominik
A1  - Weihs, Anna
A1  - Junger, Wolfgang
A1  - Sitte, Harald
A1  - Schaden, Wolfgang
T1  - Extracorporeal shock waves - a novel method of mechanostimulation in tissue regeneration
JF  - Journal of Tissue Engineering and Regenerative Medicine
KW  - Shockwave treatment
KW  - Mechanostimulation
Y1  - 2018
VL  - 1
IS  - 6
SP  - 380
EP  - 380
ER  - 
TY  - JOUR
A1  - Martin M., Frank
A1  - Kollmitzer, Josef
A1  - Redl, Heinz
A1  - Rünzler, Dominik
T1  - Shear force stimulation of adipose-tissue derived stem cells in a novel bioreactor
JF  - Journal of Tissue Engineering and Regenerative Medicine
KW  - Stem Cells
KW  - Adipose
Y1  - 2018
VL  - 1
IS  - 6
SP  - 340
EP  - 340
ER  - 
TY  - GEN
A1  - Weihs, Anna
A1  - Junger, Wolgang G.
A1  - Schaden, Wolfgang
A1  - Sitte, Harald H.
A1  - Rünzler, Dominik
T1  - Extracellular ATP release - a potential benefit in shock wave treatment
KW  - Shockwave
Y1  - 2019
ER  - 
TY  - JOUR
A1  - Milan-Lobo, Laura
A1  - Gsandtner, Ingrid
A1  - Gaubitzer, Erwin
A1  - Rünzler, Dominik
A1  - Buchmayer, Florian
A1  - Köhler, Gottfried
A1  - Bonci, Antonello
A1  - Freissmuth, Michael
A1  - Sitte, Harald H.
T1  - Subtype-specific differences in corticotropin-releasing factor receptor complexes detected by fluorescence spectroscopy
JF  - Molecular Pharmacology (mol pharmacol)
KW  - Spectroscopy
Y1  - 2019
IS  - 76(6)
SP  - 1196
EP  - 1210
ER  - 
TY  - CHAP
A1  - Weihs, Anna
A1  - Knebl, Gerald
A1  - Redl, Heinz
A1  - Rünzler, Dominik
T1  - Evaluation of cell migration methods in 3D hydrogels for tissue engineering applications
T2  - 3. Forschungsforum der österreichischen Fachhochschulen / Fachhochschule Kärnten
KW  - Cells
Y1  - 2019
SN  - 978-3-853912850
SP  - 490
EP  - 491
ER  - 
TY  - CHAP
A1  - Knebl, Gerald
A1  - Weihs, Anna
A1  - Weingant, Michaela
A1  - Steininger, Thomas
A1  - Redl, Heinz
A1  - Rünzler, Dominik
T1  - Automatisierte Datenauswertung eines Boyden-Mikro-Chemotaxis-Kammer Zell-Migrations Assays.
T2  - 2. Forschungsforum der österreichischen Fachhochschulen
KW  - Cells
KW  - Data Analysis
Y1  - 2019
SN  - 978-3-8322-7023-0
SP  - 412
EP  - 417
ER  - 
TY  - CHAP
A1  - Rünzler, Dominik
A1  - Knebl, Gerald
A1  - Peterbauer, A.
A1  - Wolbank, Susanne
A1  - Morton, Tatjana J.
A1  - Redl, Heinz
T1  - Darstellung fluoreszenzmarkierter adulter Stammzellen in drei-dimensionaler Zellkultur mittels Konfokaler Laser Scanning Mikroskopie
T2  - Erstes Forschungsforum der österreichischen Fachhochschulen
KW  - Cells
Y1  - 2019
SP  - 311
EP  - 316
ER  - 
TY  - JOUR
A1  - Grunt, Thomas
A1  - Tomek, Katharina
A1  - Wagner, Renate
A1  - Puckmair, Klaudia
A1  - Kainz, Birgit
A1  - Rünzler, Dominik
A1  - Gaiger, Alexander
A1  - Köhler, Gottfried
A1  - Zielinski, Christoph
T1  - Upregulation of retinoic acid receptor-beta by the epidermal growth factor-receptor inhibitor PD153035 is not mediated by blockade of ErbB pathways
JF  - Journal of Cell Physiology
KW  - Cells
Y1  - 2019
IS  - 211(3)
SP  - 803
EP  - 815
ER  - 
TY  - JOUR
A1  - Spurny, Radovan
A1  - Abdoulrahman, Kamaran
A1  - Janda, Lubomir
A1  - Rünzler, Dominik
A1  - Köhler, Gottfried
A1  - Castanon, Maria J.
A1  - Wiche, Gerhard
T1  - Oxidation and nitrosylation of cysteines proximal to the intermediate filament (IF)-binding site of plectin: effects on structure and vimentin binding and involvement in IF collapse
JF  - Journal of Biological Chemistry
KW  - Oxidation
Y1  - 2019
IS  - 282(11)
SP  - 8175
EP  - 8187
ER  - 
TY  - GEN
A1  - Rünzler, Dominik
T1  - Darstellung fluoreszenzmarkierter adulter Stammzellen in drei-dimensionaler Zellkultur mittels Konfokaler Laser Scanning Mikroskopie
KW  - Cells
Y1  - 2019
ER  - 
TY  - GEN
A1  - Rünzler, Dominik
T1  - Automatisierte Datenauswertung eines Boyden-Mikro-Chemotaxis-Kammer Zell-Migrations Assays
KW  - Cells
KW  - Data Analysis
Y1  - 2019
ER  - 
TY  - CHAP
A1  - Milan-Lobo, Laura
A1  - Rünzler, Dominik
A1  - Gaubitzer, Erwin
A1  - Köhler, Gottfried
A1  - Bonci, Antonello
A1  - Freissmuth, Michael
A1  - Sitte, Harald H.
T1  - CRF receptors form dynamic complexes at the plasma membrane but only type 2 receptor increases lateral mobility after CRF binding
T2  - FEBS Journal
KW  - Plasma Membrane
Y1  - 2019
ER  - 
TY  - CHAP
A1  - Kaisler, Raphaela
A1  - Pázmándi, Christian
A1  - Ortner, Anna
A1  - Haberl, Ines
A1  - Köhler, Gottfried
A1  - Rünzler, Dominik
A1  - Artl, Andreas
A1  - Andreae, Fritz
A1  - Mosgöller, Wilhelm
T1  - Vasoactive intestinal peptide conjugate internalisation as strategy for cytoplasmic drug delivery
T2  - Journal of Molecular Neuroscience
KW  - Cytplasmic Drug Delivery
Y1  - 2019
ER  - 
TY  - JOUR
A1  - Wruss, Jürgen
A1  - Rünzler, Dominik
A1  - Steiger, Christina
A1  - Chiba, Peter
A1  - Köhler, Gottfried
A1  - Blaas, Dieter
T1  - Attachment of VLDL receptors to an icosahedral virus along the 5-fold symmetry axis: multiple binding modes evidenced by fluorescence correlation spectroscopy
JF  - Biochemistry
KW  - Cells
Y1  - 2019
IS  - 46(21)
SP  - 6331
EP  - 6339
ER  - 
TY  - JOUR
A1  - Maier, Christina
A1  - Rünzler, Dominik
A1  - Schindelar, Julia
A1  - Grabner, Gottfried
A1  - Waldhäusl, Werner Klaus
A1  - Köhler, Gottfried
A1  - Luger, Anton
T1  - G-protein-coupled glucocorticoid receptors on the pituitary cell membrane
JF  - Journal of Cell Science
KW  - Cells
Y1  - 2019
IS  - 118(15)
SP  - 3353
EP  - 3361
ER  - 
TY  - JOUR
A1  - Maier, Christina
A1  - Rünzler, Dominik
A1  - Wagner, Ludwig
A1  - Grabner, Günther
A1  - Köhler, Gottfried
A1  - Lugner, Anton
T1  - Evidence for specific glucocorticoid binding sites on the cell membrane by fluorescence correlation spectroscopy
JF  - Single Moleculus
KW  - Cells
Y1  - 2019
IS  - 3(4)
SP  - 211
EP  - 216
ER  - 
TY  - JOUR
A1  - Huber-Gries, Carina
A1  - Ilk, Nicola
A1  - Rünzler, Dominik
A1  - Egelseer, Eva-Maria
A1  - Weigert, Stefan
A1  - Sleytr, Uwe
T1  - The three S-layer-like homology motifs of the S-layer protein SbpA of Bacillus sphaericus CCM 2177 are not sufficient for binding to the pyruvylated secondary cell wall polymer
JF  - Molecular Microbiology
KW  - Proteins
Y1  - 2018
VL  - 55
IS  - 1
SP  - 197
EP  - 205
ER  - 
TY  - GEN
A1  - Purtscher, Michaela
A1  - Ergir, Ece
A1  - Szwarc, Dorota
A1  - Monforte Vila, Xavier
A1  - Rünzler, Dominik
A1  - Huber-Gries, Carina
T1  - A microfluidic-based easy-to-use cardiac tissue model for drug screening applications
KW  - Tissue Generation
KW  - Drug Screening
KW  - Cardiac
Y1  - 2018
ER  - 
TY  - GEN
A1  - Hromada, Carina
A1  - Tomasch, Janine
A1  - Weihs, Anna
A1  - Rünzler, Dominik
A1  - Teuschl, Andreas
T1  - Engineering of 3D Tissue Constructs Using our Novel MagneTissue Bioreactor as Alternatives to Animal Models
KW  - Bioreactor
KW  - Biomaterials
Y1  - 
ER  - 
TY  - JOUR
A1  - Leeb, Christine
A1  - Leitner, Rita
A1  - Pichler, Verena
A1  - Huber-Gries, Carina
A1  - Rünzler, Dominik
A1  - Jesenberger, Veronika
T1  - Einführung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich
JF  - Zeitschrift für Hochschulentwicklung (ZFHE)
KW  - Life Science
KW  - Problem Based Learning
KW  - Education
Y1  - 2018
VL  - 11
IS  - 3
SP  - 107
EP  - 121
ER  - 
TY  - JOUR
A1  - Rieder, Bernhard
A1  - Weihs, Anna
A1  - Weidinger, Adelheid
A1  - Sczwarc, Dorota
A1  - Nürnberger, Sylvia
A1  - Redl, Heinz
A1  - Rünzler, Dominik
A1  - Huber-Gries, Carina
A1  - Teuschl, Andreas
T1  - Hydrostatic pressure-generated reactive oxygen species induce osteoarthritic conditions in cartilage pellet cultures
JF  - Scientific Reports
KW  - Bioreactor
KW  - Osteoarthritis
KW  - Cartilage
KW  - Reactive oxygen species
Y1  - 
ER  - 
TY  - CHAP
A1  - Leeb, Christine
A1  - Leitner, Rita
A1  - Pichler, Verena
A1  - Huber-Gries, Carina
A1  - Rünzler, Dominik
A1  - Jesenberger, Veronika
T1  - Einführung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich
T2  - Proceedings des Kongresses Problem-Based Learning 2016 PBL - Kompetenzen fördern, Zukunft gestalten
KW  - Life Science
KW  - Problem Based Learning
KW  - Education
Y1  - 2018
ER  - 
TY  - GEN
A1  - Leeb, Christine
A1  - Leitner, Rita
A1  - Pichler, Verena
A1  - Huber-Gries, Carina
A1  - Rünzler, Dominik
A1  - Jesenberger, Veronika
T1  - Einführung und Optimierung eines praxisorientierten PBL-Moduls im Life-Science-Bereich
KW  - Life Science
KW  - Problem Based Learning
KW  - Education
Y1  - 2018
ER  - 
TY  - JOUR
A1  - Priglinger, Eleni
A1  - Schuh, Christina
A1  - Steffenhagen, Carolin
A1  - Wurzer, Christoph
A1  - Maier, Julia
A1  - Nürnberger, Sylvia
A1  - Holnthoner, Wolfgang
A1  - Fuchs, Christiane
A1  - Suessner, Susanne
A1  - Rünzler, Dominik
A1  - Redl, Heinz
A1  - Wolbank, Susanne
T1  - Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy.
JF  - Cytotherapy
N2  - BACKGROUND:

Cell-based therapies with autologous adipose tissue-derived cells have shown great potential in several clinical studies in the last decades. The majority of these studies have been using the stromal vascular fraction (SVF), a heterogeneous mixture of fibroblasts, lymphocytes, monocytes/macrophages, endothelial cells, endothelial progenitor cells, pericytes and adipose-derived stromal/stem cells (ASC) among others. Although possible clinical applications of autologous adipose tissue-derived cells are manifold, they are limited by insufficient uniformity in cell identity and regenerative potency.
METHODS:

In our experimental set-up, low-energy extracorporeal shock wave therapy (ESWT) was performed on freshly obtained human adipose tissue and isolated adipose tissue SVF cells aiming to equalize and enhance stem cell properties and functionality.
RESULTS:

After ESWT on adipose tissue we could achieve higher cellular adenosine triphosphate (ATP) levels compared with ESWT on the isolated SVF as well as the control. ESWT on adipose tissue resulted in a significantly higher expression of single mesenchymal and vascular marker compared with untreated control. Analysis of SVF protein secretome revealed a significant enhancement in insulin-like growth factor (IGF)-1 and placental growth factor (PLGF) after ESWT on adipose tissue.
DISCUSSION:

Summarizing we could show that ESWT on adipose tissue enhanced the cellular ATP content and modified the expression of single mesenchymal and vascular marker, and thus potentially provides a more regenerative cell population. Because the effectiveness of autologous cell therapy is dependent on the therapeutic potency of the patient's cells, this technology might raise the number of patients eligible for autologous cell transplantation.
KW  - Shockwave Therapy
KW  - Tissue Regeneration
KW  - Regenerative Medicine
Y1  - 
SP  - 1079
EP  - 1095
ER  - 
TY  - JOUR
A1  - Cieślik-Boczula, Katarzyna
A1  - Küpcü, Seta
A1  - Rünzler, Dominik
A1  - Koll, Aleksander
A1  - Köhler, Gottfried
T1  - Effects of the phenolic lipid 3-pentadecylphenol on phospholipid bilayer organization
JF  - Journal of Molecular Structure
KW  - Phospholipid Bilayer
Y1  - 2019
IS  - 919(1-3)
SP  - 373
EP  - 380
ER  - 
TY  - CHAP
A1  - Knebl, Gerald
A1  - Morton, Tatjana J.
A1  - Redl, Heinz
A1  - Rünzler, Dominik
T1  - Mechanical stimulation of cells in 3-dimensional fibrin constructs using a bioreactor
T2  - 3. Forschungsforum der österreichischen Fachhochschulen / Fachhochschule Kärnten
KW  - Cells
KW  - Bioreactor
Y1  - 2019
SP  - 492
EP  - 493
ER  - 
TY  - JOUR
A1  - Schneider, Karl Heinrich
A1  - Aigner, Petra
A1  - Holnthoner, Wolfgang
A1  - Monforte Vila, Xavier
A1  - Nürnberger, Sylvia
A1  - Rünzler, Dominik
A1  - Redl, Heinz
A1  - Teuschl, Andreas
T1  - Decellularized human placenta chorion matrix as a favorable source of small-diameter vascular grafts
JF  - Acta Biomaterialia
KW  - Grafting
KW  - Tissue Engineering
Y1  - 2018
ER  - 
TY  - JOUR
A1  - Rohringer, Sabrina
A1  - Holnthoner, Wolfgang
A1  - Hackl, Matthias
A1  - Weihs, Anna
A1  - Rünzler, Dominik
A1  - Skalicky, Susanna
A1  - Karbiener, Michael
A1  - Scheideler, Marcel
A1  - Pröll, Johannes
A1  - Gabriel, Christian
A1  - Schweighofer, Bernhard
A1  - Gröger, Marion
A1  - Spittler, Andreas
A1  - Grillari, Johannes
A1  - Redl, Heinz
T1  - Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells.
JF  - PLoS one
KW  - Shockwave
Y1  - 
ER  - 
TY  - GEN
A1  - Liousia, Varvara
A1  - Salzer, Elias
A1  - Mandt, Denise
A1  - Rünzler, Dominik
T1  - The impact of ethanol in vitro and in vivo: a comparative study
KW  - In Vivo
KW  - In Vitro
KW  - Ethanol
Y1  - 2018
ER  - 
TY  - GEN
A1  - Liousia, Varvara
A1  - Rünzler, Dominik
T1  - Stage- and dose-dependent effects of methanol and ethanol on the locomotor activity of zebrafish larvae
KW  - Locomotor Activity
KW  - Zebrafish
Y1  - 2018
ER  -