TY  - JOUR
A1  - Khimich, Margarita A.
A1  - Prosolov, Konstantin A.
A1  - Mishurova, Tatiana
A1  - Evsevleev, Sergej
A1  - Monforte, Xavier
A1  - Teuschl, Andreas H.
A1  - Slezak, Paul
A1  - Ibragimov, Egor A.
A1  - Saprykin, Alexander A.
A1  - Kovalevskaya, Zhanna G.
A1  - Dmitriev, Andrey I.
A1  - Bruno, Giovanni
A1  - Sharkeev, Yurii P.
T1  - Advances in Laser Additive Manufacturing of Ti-Nb Alloys: From Nanostructured Powders to Bulk Objects
JF  - Nanomaterials (Basel)
N2  - The additive manufacturing of low elastic modulus alloys that have a certain level of porosity for biomedical needs is a growing area of research. Here, we show the results of manufacturing of porous and dense samples by a laser powder bed fusion (LPBF) of Ti-Nb alloy, using two distinctive fusion strategies. The nanostructured Ti-Nb alloy powders were produced by mechanical alloying and have a nanostructured state with nanosized grains up to 90 nm. The manufactured porous samples have pronounced open porosity and advanced roughness, contrary to dense samples with a relatively smooth surface profile. The structure of both types of samples after LPBF is formed by uniaxial grains having micro- and nanosized features. The inner structure of the porous samples is comprised of an open interconnected system of pores. The volume fraction of isolated porosity is 2 vol. % and the total porosity is 20 vol. %. Cell viability was assessed in vitro for 3 and 7 days using the MG63 cell line. With longer culture periods, cells showed an increased cell density over the entire surface of a porous Ti-Nb sample. Both types of samples are not cytotoxic and could be used for further in vivo studies.
KW  - Tissue Engineering
KW  - Biomaterials
KW  - Laser Additive Manufacturing
KW  - Bulk Objects
Y1  - 
VL  - 11
IS  - 5 / 1159
ER  -