TY - JOUR A1 - Eder, Gabriele C. A1 - Voronko, Yuliya A1 - Dimitriadis, Simon A1 - Knöbl, Karl A1 - Ujvári, Gusztáv A1 - Berger, Karl A. A1 - Halwachs, Martin A1 - Neumaier, Lukas A1 - Hirschl, Christina T1 - Climate specific accelerated ageing tests and evaluation of ageing induced electrical, physical, and chemical changes JF - Progress in Photovoltaics: Research and Applications 2018 KW - Photovoltaik KW - Degradation Y1 - N1 - DOI:10.1002/pip.3090 SP - 1 EP - 16 ER - TY - JOUR A1 - Muehleisen, Wolfgang A1 - Eder, Gabriele C. A1 - Voronko, Yuliya A1 - Spielberger, Markus A1 - Sonnleitner, Horst A1 - Knöbl, Karl A1 - Ebner, Rita A1 - Ujvari, Gusztáv A1 - Hirschl, Christina T1 - Outdoor detection and visualization of hailstorm damages of photovoltaic plants JF - Renewable Energy KW - Photovoltaics KW - Damage Detection KW - Hailstorms Y1 - 2018 IS - 118 SP - 138 EP - 145 ER - TY - JOUR A1 - Bernhard, Jonathan C A1 - Marolt Presen, Darja A1 - Li, Ming A1 - Monforte, Xavier A1 - Ferguson, James A1 - Leinfellner, Gabriele A1 - Heimel, Patrick A1 - Betti, Susanne L A1 - Shu, Sharon A1 - Teuschl-Woller, Andreas H A1 - Tangl, Stefan A1 - Redl, Heinz A1 - Vunjak-Novakovic, Gordana T1 - Effects of Endochondral and Intramembranous Ossification Pathways on Bone Tissue Formation and Vascularization in Human Tissue-Engineered Grafts JF - Cells N2 - Bone grafts can be engineered by differentiating human mesenchymal stromal cells (MSCs) via the endochondral and intramembranous ossification pathways. We evaluated the effects of each pathway on the properties of engineered bone grafts and their capacity to drive bone regeneration. Bone-marrow-derived MSCs were differentiated on silk scaffolds into either hypertrophic chondrocytes (hyper) or osteoblasts (osteo) over 5 weeks of in vitro cultivation, and were implanted subcutaneously for 12 weeks. The pathways' constructs were evaluated over time with respect to gene expression, composition, histomorphology, microstructure, vascularization and biomechanics. Hypertrophic chondrocytes expressed higher levels of osteogenic genes and deposited significantly more bone mineral and proteins than the osteoblasts. Before implantation, the mineral in the hyper group was less mature than that in the osteo group. Following 12 weeks of implantation, the hyper group had increased mineral density but a similar overall mineral composition compared with the osteo group. The hyper group also displayed significantly more blood vessel infiltration than the osteo group. Both groups contained M2 macrophages, indicating bone regeneration. These data suggest that, similar to the body's repair processes, endochondral pathway might be more advantageous when regenerating large defects, whereas intramembranous ossification could be utilized to guide the tissue formation pattern with a scaffold architecture. KW - bone tissue engineering KW - endochondral KW - mesenchymal stromal cells KW - ossification KW - intramembranous Y1 - U6 - http://dx.doi.org/10.3390/cells11193070 VL - 11 IS - 19:3070 ER -