TY  - GEN
A1  - Traxler, Lukas
A1  - Balz, Andrea
T1  - Current Advances in the Optical Characterization of Intraocular Lenses
T2  - Abstracts of the 2022 Joint Annual Conference of the Austrian (ÖGBMT), German (VDE DGBMT) and Swiss (SSBE) Societies for Biomedical Engineering, including the 14th Vienna International Workshop on Functional Electrical Stimulation
KW  - Intraocular Lenses
Y1  - 
U6  - http://dx.doi.org/https://doi.org/10.1515/bmt-2022-2001
SP  - 102
ER  - 
TY  - JOUR
A1  - Bernhard, Jonathan C
A1  - Marolt Presen, Darja
A1  - Li, Ming
A1  - Monforte, Xavier
A1  - Ferguson, James
A1  - Leinfellner, Gabriele
A1  - Heimel, Patrick
A1  - Betti, Susanne L
A1  - Shu, Sharon
A1  - Teuschl-Woller, Andreas H
A1  - Tangl, Stefan
A1  - Redl, Heinz
A1  - Vunjak-Novakovic, Gordana
T1  - Effects of Endochondral and Intramembranous Ossification Pathways on Bone Tissue Formation and Vascularization in Human Tissue-Engineered Grafts
JF  - Cells
N2  - Bone grafts can be engineered by differentiating human mesenchymal stromal cells (MSCs) via the endochondral and intramembranous ossification pathways. We evaluated the effects of each pathway on the properties of engineered bone grafts and their capacity to drive bone regeneration. Bone-marrow-derived MSCs were differentiated on silk scaffolds into either hypertrophic chondrocytes (hyper) or osteoblasts (osteo) over 5 weeks of in vitro cultivation, and were implanted subcutaneously for 12 weeks. The pathways' constructs were evaluated over time with respect to gene expression, composition, histomorphology, microstructure, vascularization and biomechanics. Hypertrophic chondrocytes expressed higher levels of osteogenic genes and deposited significantly more bone mineral and proteins than the osteoblasts. Before implantation, the mineral in the hyper group was less mature than that in the osteo group. Following 12 weeks of implantation, the hyper group had increased mineral density but a similar overall mineral composition compared with the osteo group. The hyper group also displayed significantly more blood vessel infiltration than the osteo group. Both groups contained M2 macrophages, indicating bone regeneration. These data suggest that, similar to the body's repair processes, endochondral pathway might be more advantageous when regenerating large defects, whereas intramembranous ossification could be utilized to guide the tissue formation pattern with a scaffold architecture.
KW  - bone tissue engineering
KW  - endochondral
KW  - mesenchymal stromal cells
KW  - ossification
KW  - intramembranous
Y1  - 
U6  - http://dx.doi.org/10.3390/cells11193070
VL  - 11
IS  - 19:3070
ER  - 
TY  - JOUR
A1  - Ahlborn, Felix
A1  - Kupka, Friedrich
A1  - Weiss, Achim
A1  - Flaskamp, Martin
T1  - Stellar evolution models with overshooting based on 3-equation non-local theories: II. Main sequence models of A- and B-type stars
JF  - Astronomy & Astrophysics
KW  - convection
KW  - turbulence
KW  - stars: evolution
KW  - stars: interiors
Y1  - 
U6  - http://dx.doi.org/https://doi.org/10.1051/0004-6361/202243126
IS  - Volume 667
SP  - Article Number A97
ER  - 
TY  - JOUR
A1  - Kupka, Friedrich
A1  - Ahlborn, Felix
A1  - Weiss, Achim
T1  - Stellar evolution models with overshooting  based on 3-equation non-local theories: I. Physical basics and the computation of the dissipation rate
JF  - Astronomy & Astrophysics
KW  - convection
KW  - turbulence
KW  - stars: evolution
KW  - stars: interiors
Y1  - 
U6  - http://dx.doi.org/https://doi.org/10.1051/0004-6361/202243125
IS  - Volume 667
SP  - Article Number A96
ER  - 
TY  - THES
A1  - Tomasch, Janine
T1  - Strategies to improve the myogenic outcome of skeletal muscle tissue engineering approaches through optimization of biomaterial properties and mechanical stimuli
KW  - muscle
KW  - bioreactor
KW  - tissue engineering
KW  - fibrin
KW  - biomaterial
Y1  - 
ER  - 
TY  - GEN
A1  - Kupka, Friedrich
T1  - Requirements from WP123200
KW  - astrophysics
Y1  - 
ER  - 
TY  - GEN
A1  - Kupka, Friedrich
T1  - Numerical Simulation of A-type and White Dwarf Stars
KW  - astrophysics
Y1  - 
ER  -