TY - CHAP A1 - Salzbrunn, Benedikt A1 - Dolezal, Dominik A1 - Pucher, Robert T1 - User Experience Database: Student-Generated Content in Higher Education T2 - Proceedings of the 6th International Conference of Education, Research and Innovation (ICERI 2013) KW - User Experience KW - Education Y1 - 2018 ER - TY - GEN A1 - Salzbrunn, Benedikt A1 - Dolezal, Dominik A1 - Pucher, Robert T1 - Usability-Didaktik, wie kann der Fokus auf Usability bei der Softwareentwicklung erfolgreich unterrichtet werden? KW - Usability KW - Education Y1 - 2018 ER - TY - GEN A1 - Salzbrunn, Benedikt A1 - Dolezal, Dominik A1 - Pucher, Robert T1 - User Experience Database: Student-Generated Content in Higher Education KW - User Experience KW - Education Y1 - 2018 ER - TY - BOOK A1 - Teschl, Gerald A1 - Teschl, Susanne T1 - Mathematik für Informatiker, Band 1, Diskrete Mathematik und Lineare Algebra KW - Mathematics Y1 - PB - Springer Verlag ER - TY - JOUR A1 - Jesenberger, Veronika A1 - Zmajkovicova, Katarina A1 - Catalanotti, Federica A1 - Baumgartner, Christian A1 - Reyes, Gloria Ximena A1 - Baccarini, Manuela T1 - MEK1 is required for PTEN membrane recruitment, AKT regulation, and the maintenance of peripheral tolerance JF - Mol. Cell N2 - The Raf/MEK/ERK and PI3K/Akt pathways are prominent effectors of oncogenic Ras. These pathways negatively regulate each other, but the mechanism involved is incompletely understood. We now identify MEK1 as an essential regulator of lipid/protein phosphatase PTEN, through which it controls phosphatidylinositol-3-phosphate accumulation and AKT signaling. MEK1 ablation stabilizes AKT activation and, in vivo, causes a lupus-like autoimmune disease and myeloproliferation. Mechanistically, MEK1 is necessary for PTEN membrane recruitment as part of a ternary complex containing the multidomain adaptor MAGI1. Complex formation is independent of MEK1 kinase activity but requires phosphorylation of T292 on MEK1 by activated ERK. Thus, inhibiting the ERK pathway reduces PTEN membrane recruitment, increasing phosphatidylinositol-3-phosphate accumulation and AKT activation. Our data offer a conceptual framework for the observation that activation of the PI3K pathway frequently mediate resistance to MEK inhibitors and for the promising results obtained by combined MEK/PI3K inhibition in preclinical cancer models. KW - MEK1 pathway KW - membrane recruitment KW - preclinical cancer models Y1 - 2020 VL - 2013 IS - 50 SP - 43 EP - 55 ER - TY - JOUR A1 - Buta, Christiane A1 - David, Robert A1 - Dressel, Ralf A1 - Emgard, Mia A1 - Fuchs, Christiane A1 - Gross, Ulrike A1 - Healy, Lyn A1 - Hescheler, Jürgen A1 - Kolar, Roman A1 - Martin, Ulrich A1 - Mikkers, Harald A1 - Müller, Franz-Josef A1 - Schneider, Rebekka A1 - Seiler, Andrea A1 - Spielmann, Horst A1 - Weitzer, Georg T1 - REconsidering pluripotency tests: do we still need teratoma assays? JF - Stem Cell Research KW - Assay KW - Stem Cells Y1 - 2018 VL - 11 IS - 1 SP - 552 EP - 562 ER - TY - JOUR A1 - Hohlrieder, Manfred A1 - Teuschl, Andreas A1 - Cicha, Klaus A1 - van Griensven, Martijn A1 - Redl, Heinz A1 - Stampfl, Jürgen T1 - Bioreactor and scaffold design for the mechanical stimulation of anterior cruciate ligament grafts JF - Biomedical materials and engineering KW - Bioreactors KW - Ligaments KW - Grafting Y1 - 2018 VL - 23 IS - 3 SP - 225 EP - 237 ER - TY - JOUR A1 - Dungel, Peter A1 - Teuschl, Andreas A1 - Banerjee, Asmita A1 - Paier-Pourani, Jamile A1 - Redl, Heinz A1 - Kozlov, Andrey T1 - Impact of mitochondria on nitrite metabolism in HL-1 cardiomyocytes JF - Frontiers in Physiology KW - Nitrite KW - Metabolism Y1 - 2018 IS - 4 ER - TY - JOUR A1 - Teuschl, Andreas A1 - Nürnberger, Sylvia A1 - Redl, Heinz A1 - Nau, Thomas T1 - Articular cartilage tissue regeneration: current research strategies and outlook for the future JF - European Surgery KW - Tissue Regeneration KW - Cartilage Tissue Y1 - 2018 VL - 45 IS - 3 SP - 142 EP - 153 ER - TY - JOUR A1 - Teuschl, Andreas A1 - van Griensven, Martijn A1 - Redl, Heinz T1 - Sericin removal from raw Bombys mori silk scaffolds of high hierarchical order JF - Tissue Eng Part C Methods KW - Scaffold KW - Sericin Y1 - 2018 ER - TY - GEN A1 - Pucher, Robert T1 - Psychologie der Wahrnehmung in der IT KW - Psychology KW - Perception KW - IT Y1 - 2018 ER - TY - JOUR A1 - Fink, Matthias A1 - Keßler, Alexander A1 - Schmid, Judith A1 - Stummer, Katharina T1 - Learning by Almost Doing - Theoretische Argumente und empirische Ergebnisse zur Wirkung von Fallstudien in der Entrepreneurship-Ausbildung. JF - Zeitschrift für KMU und Entrepreneurship KW - SME KW - Entrepreneurship KW - Education Y1 - SP - 173 EP - 196 ER - TY - CHAP A1 - Aigner, Benjamin A1 - Rössler, Peter T1 - A Low-cost Sound Generator for an Electric Quad Bike T2 - MECO2013 Conference, 16-20 June, 2013, Budva, Montenegro KW - Embedded Systems Y1 - 2019 ER - TY - CHAP A1 - Egger, Richard A1 - Weber, Sebastian A1 - Schmid, Judith T1 - Aktuelle Kooperationsneigung österreichischer Bauunternehmer in der Grenzregion T2 - Die Entwicklung von KMU in der Baubranche (Rozvoj malých a středních podniků ve stavebnictví), Brünn Masaryk Universität KW - SME KW - Construction Y1 - SN - ISBN 978-80-210-6187-3 SP - 80 EP - 88 CY - Brünn ER - TY - JOUR A1 - Keßler, Alexander A1 - Stummer, Katharina A1 - Schmid, Judith T1 - Von der Wirtschaftskrise zur Unternehmenskrise JF - KMU in der Krise. Strategien zur Krisenvermeidung und Krisenbewältigung KW - SME KW - Economic Crisis Y1 - SP - 11 EP - 38 ER - TY - JOUR A1 - Schmid, Judith A1 - Rößl, Dietmar T1 - Entrepreneurial Marketing als Erfolgsfaktor in der Krise JF - KMU in der Krise. Strategien zur Krisenvermeidung und Krisenbewältigung KW - SME KW - Economic Crisis Y1 - SP - 97 EP - 129 ER - TY - CHAP A1 - Ghaemi, Sara A1 - Schneider, Simon T1 - Potential analysis of residential Demand Response using GridLAB-D T2 - IECON 2013 - 39th Annual Conference of the IEEE Industrial Electronics Society KW - Potential Analysis Y1 - SP - 8039 EP - 8045 ER - TY - CHAP A1 - Kollmitzer, Christian T1 - Die Rolle von Aufgaben in der technischen hochschulischen Lehre T2 - Berufsbegleitende Studiengänge als Herausforderung für Curriculumentwicklung und Hochschuldidaktik. Beiträge zum 2. Tag der Lehre KW - Education KW - Technical University KW - Exercises Y1 - 2018 SP - 71 EP - 81 ER - TY - GEN A1 - Kollmitzer, Christian T1 - Die Rolle von Aufgaben in der technischen hochschulischen Lehre KW - Education KW - Technical University KW - Exercises Y1 - 2018 ER - TY - CHAP A1 - Horauer, Martin A1 - Schuster, Harald A1 - Balog, Peter T1 - Experimental Assessment of the Clique Problem in FlexRay T2 - Proceedings of the 8th ASME/IEEE International Conference on Mechatronic and Embedded Systems and Applications, Portland OR, USA, Aug. 04-07, 2013 KW - Embedded Systems KW - FlexRay Y1 - 2019 ER -