TY - JOUR A1 - Tomasch, Janine A1 - Maleiner, Babette A1 - Heher, Philipp A1 - Rufin, Manuel A1 - Andriotis, Orestis G. A1 - Thurner, Philipp J. A1 - Redl, Heinz A1 - Fuchs, Christiane A1 - Teuschl-Woller, Andreas H. T1 - Changes in Elastic Moduli of Fibrin Hydrogels Within the Myogenic Range Alter Behavior of Murine C2C12 and Human C25 Myoblasts Differently JF - Froniers in Bioengineering and Biotechnology N2 - Fibrin hydrogels have proven highly suitable scaffold materials for skeletal muscle tissue engineering in the past. Certain parameters of those types of scaffolds, however, greatly affect cellular mechanobiology and therefore the myogenic outcome. The aim of this study was to identify the influence of apparent elastic properties of fibrin scaffolds in 2D and 3D on myoblasts and evaluate if those effects differ between murine and human cells. Therefore, myoblasts were cultured on fibrin-coated multiwell plates (“2D”) or embedded in fibrin hydrogels (“3D”) with different elastic moduli. Firstly, we established an almost linear correlation between hydrogels’ fibrinogen concentrations and apparent elastic moduli in the range of 7.5 mg/ml to 30 mg/ml fibrinogen (corresponds to a range of 7.7–30.9 kPa). The effects of fibrin hydrogel elastic modulus on myoblast proliferation changed depending on culture type (2D vs 3D) with an inhibitory effect at higher fibrinogen concentrations in 3D gels and vice versa in 2D. The opposite effect was evident in differentiating myoblasts as shown by gene expression analysis of myogenesis marker genes and altered myotube morphology. Furthermore, culture in a 3D environment slowed down proliferation compared to 2D, with a significantly more pronounced effect on human myoblasts. Differentiation potential was also substantially impaired upon incorporation into 3D gels in human, but not in murine, myoblasts. With this study, we gained further insight in the influence of apparent elastic modulus and culture type on cellular behavior and myogenic outcome of skeletal muscle tissue engineering approaches. Furthermore, the results highlight the need to adapt parameters of 3D culture setups established for murine cells when applied to human cells. KW - Tissue Engineering KW - Fibrin KW - Hydrogel KW - Biomaterials KW - Cell Culture Y1 - VL - 10 SP - 836520 ER - TY - JOUR A1 - Angelova, Liliya A1 - Daskalova, Albena A1 - Filipov, Emil A1 - Monforte Vila, Xavier A1 - Tomasch, Janine A1 - Avdeev, Georgi A1 - Teuschl-Woller, Andreas Herbert A1 - Buchvarov, Ivan T1 - Optimizing the Surface Structural and Morphological Properties of Silk Thin Films via Ultra-Short Laser Texturing for Creation of Muscle Cell Matrix Model JF - Polymers N2 - Temporary scaffolds that mimic the extracellular matrix's structure and provide a stable substratum for the natural growth of cells are an innovative trend in the field of tissue engineering. The aim of this study is to obtain and design porous 2D fibroin-based cell matrices by femtosecond laser-induced microstructuring for future applications in muscle tissue engineering. Ultra-fast laser treatment is a non-contact method, which generates controlled porosity-the creation of micro/nanostructures on the surface of the biopolymer that can strongly affect cell behavior, while the control over its surface characteristics has the potential of directing the growth of future muscle tissue in the desired direction. The laser structured 2D thin film matrices from silk were characterized by means of SEM, EDX, AFM, FTIR, Micro-Raman, XRD, and 3D-roughness analyses. A WCA evaluation and initial experiments with murine C2C12 myoblasts cells were also performed. The results show that by varying the laser parameters, a different structuring degree can be achieved through the initial lifting and ejection of the material around the area of laser interaction to generate porous channels with varying widths and depths. The proper optimization of the applied laser parameters can significantly improve the bioactive properties of the investigated 2D model of a muscle cell matrix. Keywords: biopolymers; femtosecond laser processing; muscle cell matrix 2D model; muscle tissue engineering; silk fibroin. KW - Tissue Engineering KW - Muscle Cell matrix Model KW - Silk Scaffold KW - Surface Structure Y1 - VL - 2022 IS - 14(13), 2584 ER - TY - JOUR A1 - Munsch, Nicolas A1 - Gruarin, Stefanie A1 - Nateqi, Jama A1 - Lutz, Thomas A1 - Binder, Michael A1 - Aberle, Judith H. A1 - Martin, Alistair A1 - Knapp, Bernhard T1 - Symptoms associated with a COVID-19 infection among a non-hospitalized cohort in Vienna JF - Wiener Klinische Wochenschrift / The Central European Journal of Medicine N2 - Background: Most clinical studies report the symptoms experienced by those infected with coronavirus disease 2019 (COVID-19) via patients already hospitalized. Here we analyzed the symptoms experienced outside of a hospital setting. Methods: The Vienna Social Fund (FSW; Vienna, Austria), the Public Health Services of the City of Vienna (MA15) and the private company Symptoma collaborated to implement Vienna's official online COVID-19 symptom checker. Users answered 12 yes/no questions about symptoms to assess their risk for COVID-19. They could also specify their age and sex, and whether they had contact with someone who tested positive for COVID-19. Depending on the assessed risk of COVID-19 positivity, a SARS-CoV‑2 nucleic acid amplification test (NAAT) was performed. In this publication, we analyzed which factors (symptoms, sex or age) are associated with COVID-19 positivity. We also trained a classifier to correctly predict COVID-19 positivity from the collected data. Results: Between 2 November 2020 and 18 November 2021, 9133 people experiencing COVID-19-like symptoms were assessed as high risk by the chatbot and were subsequently tested by a NAAT. Symptoms significantly associated with a positive COVID-19 test were malaise, fatigue, headache, cough, fever, dysgeusia and hyposmia. Our classifier could successfully predict COVID-19 positivity with an area under the curve (AUC) of 0.74. Conclusion: This study provides reliable COVID-19 symptom statistics based on the general population verified by NAATs. Keywords: Chatbot; Machine learning; Self-reported; Symptom assessment; Symptom checker. KW - COVID-19 KW - Chatbot KW - Machine learning KW - Self-reported KW - Symptom assessment Y1 - VL - 2022 IS - 134 (9-10) SP - 344 EP - 350 PB - Springer ER - TY - GEN A1 - Hrastansky, Thomas T1 - Phishing: Targeting YouTube Content Creators N2 - Vortrag im Zuge des Security Monats in Form des FHTW Security Potpourri 2022 KW - Phishing KW - IT-Security KW - YouTube Y1 - ER - TY - JOUR A1 - Kuba, Markus A1 - Panholzer, Alois T1 - On bucket increasing trees, clustered increasing trees and increasing diamonds JF - Combinatorics, Probability and Computing N2 - In this work we analyse bucket increasing tree families. We introduce two simple stochastic growth processes, generating random bucket increasing trees of size n, complementing the earlier result of Mahmoud and Smythe (1995, Theoret. Comput. Sci.144 221–249.) for bucket recursive trees. On the combinatorial side, we define multilabelled generalisations of the tree families d-ary increasing trees and generalised plane-oriented recursive trees. Additionally, we introduce a clustering process for ordinary increasing trees and relate it to bucket increasing trees. We discuss in detail the bucket size two and present a bijection between such bucket increasing tree families and certain families of graphs called increasing diamonds, providing an explanation for phenomena observed by Bodini et al. (2016, Lect. Notes Comput. Sci.9644 207–219.). Concerning structural properties of bucket increasing trees, we analyse the tree parameter Kn . It counts the initial bucket size of the node containing label n in a tree of size n and is closely related to the distribution of node types. Additionally, we analyse the parameters descendants of label j and degree of the bucket containing label j, providing distributional decompositions, complementing and extending earlier results (Kuba and Panholzer (2010), Theoret. Comput. Sci.411(34–36) 3255–3273.). KW - bucket-increasing-trees KW - clustered-trees KW - stochastic-growth-processes KW - descendants KW - nodedegrees Y1 - 2021 IS - Volume 31 , Issue 4 SP - 629 EP - 661 ER - TY - JOUR A1 - Huber, Albert T1 - Remark on the quasilocal calculation of tidal heating: Energy transfer through the quasilocal surface JF - American Physical Society - Physical Review D N2 - In this paper, using the quasilocal formalism of Brown and York, the flow of energy through a closed surface containing a gravitating physical system is calculated in a way that augments earlier results on the subject by Booth and Creighton. To this end, by performing a variation of the total gravitational Hamiltonian (bulk plus boundary part), it is shown that associated tidal heating and deformation effects generally are larger than expected. This is because the aforementioned variation leads to previously unrecognized correction terms, including a bulk-to-boundary inflow term that does not appear in the original calculation of the time derivative of the Brown-York energy and leads to corrective extensions of Einstein’s quadrupole formula in the large sphere limit. KW - gravitation KW - cosmology KW - fields Y1 - VL - 105 IS - 2 ER - TY - JOUR A1 - Mairhofer, Lukas A1 - Passon, Oliver T1 - Reconsidering the Relation Between “Matter Wave Interference” and “Wave–Particle Duality” JF - Foundations of Physics N2 - Interference of more and more massive objects provides a spectacular confirmation of quantum theory. It is usually regarded as support for “wave–particle duality” and in an extension of this duality even as support for “complementarity”. We first give an outline of the historical development of these notions. Already here it becomes evident that they are hard to define rigorously, i.e. have mainly a heuristic function. Then we discuss recent interference experiments of large and complex molecules which seem to support this heuristic function of “duality”. However, we show that in these experiments the diffraction of a delocalized center-of-mass wave function depends on the interaction of the localized structure of the molecule with the diffraction element. Thus, the molecules display “dual features” at the same time, which contradicts the usual understanding of wave–particle duality. We conclude that the notion of “wave–particle duality” deserves no place in modern quantum physics. KW - Quantenmechanik KW - Welle-Teilchen-Dualismus KW - Interferenz Y1 - IS - 52/32 PB - Springer ER - TY - JOUR A1 - Kuba, Markus T1 - On multisets, interpolated multiple zeta values and limit laws. JF - Electronic Journal of Combinatorics N2 - In this work we discuss a parameter σ on weighted k-element multisets of [n]={1,…,n}. The sums of weighted k-multisets are related to k-subsets, k-multisets, as well as special instances of truncated interpolated multiple zeta values. We study properties of this parameter using symbolic combinatorics. We rederive and extend certain identities for ζtn({m}k). Moreover, we introduce random variables on the k-element multisets and derive their distributions, as well as limit laws for k or n tending to infinity. KW - k-multisets KW - k-subsets KW - truncated-multiple-zeta-values KW - interpolated-multiple-zeta-values KW - harmonic-numbers Y1 - IS - Vol. 29, Issue 1 ER - TY - GEN A1 - Mairhofer, Lukas A1 - Maiwöger, Mira T1 - Entanglement: From Philosophy to Quantum Information - and back Experiments on Bell-inequalties - threat to the Theory of Relativity? KW - Quantenphysik KW - Bell-Ungleichungen KW - Verschränkung Y1 - ER - TY - GEN A1 - Mairhofer, Lukas T1 - From foundational research to application - Training Quantum Engineers KW - Didaktik KW - Quantentechnologien KW - Quantencomputer KW - Quantenkryptographie Y1 - ER - TY - GEN A1 - Mairhofer, Lukas T1 - Dying Experiments KW - Experimentalsysteme KW - Quantenphysik KW - Science and Technology Y1 - ER - TY - JOUR A1 - Veigl, Christoph A1 - Klaus, Benjamin A1 - Aigner, Benjamin A1 - Wagner, Manuel T1 - Universal Access Panel: A Novel Approach for Accessible Smart Homes and IoT JF - Computers Helping People with Special Needs. ICCHP-AAATE 2022. Lecture Notes in Computer Science KW - Home appliances KW - Disability KW - Accessibility KW - Multimodal User Interface KW - Smart Home Y1 - VL - 2022 IS - Vol. 13342 ER - TY - GEN A1 - Knapp, Bernhard T1 - AI Engineering @ FHTW KW - Secure Services KW - eHealth & Mobility Y1 - ER - TY - GEN A1 - Knapp, Bernhard T1 - Keynote Lecture: Der Weg eines Bioinformatikers der ersten Stunde KW - Secure Services KW - eHealth & Mobility Y1 - ER - TY - GEN A1 - Knapp, Bernhard T1 - From academia to industry and back KW - Secure Services KW - eHealth & Mobility Y1 - ER - TY - JOUR A1 - Wala, Thomas T1 - Die betriebswirtschaftliche Klausur: Rechnungswesen und Controlling JF - WISU - Das Wirtschaftsstudium KW - Rechnungswesen KW - Controlling Y1 - 2022 IS - 2 / 2022 SP - 198 ff ER - TY - JOUR A1 - Bhat, Karthik Subramanya A1 - Ganglbauer, Johanna A1 - Bosch, Elina T1 - Techno–economic simulation and evaluation of scalable ‘energy cells’ locally generating renewable energy JF - e & i Elektrotechnik und Informationstechnik N2 - The ERA-Net SES project Regional Renewable Energy Cells (R2EC) [1] aims at developing a scalable system for decentralized, interacting ‘energy cells’ with a high concentration of locally generated renewable energy. ‘Energy cells’ are essentially Renewable Energy Communities (ECs) in the European context. The system aims at maximizing the utilization of locally generated renewable energy through Electrical Storage (ES) as well as high-electric applications like e‑heating, Heat Pumps (HPs), and E‑Vehicles (EVs). The system is also designed to interact with other energy cells locally, thus, improving the utilization of locally generated energy. A variety of different adjacent energy cells in three countries, Austria (AT), Belgium (BE), and Norway (NO), are analyzed, and the results are used for the development of regional and renewable energy cell systems. This approach aims at developing tailor-made solutions that meet the different local and regional requirements and the electrical energy demand of the observed energy cells. A unique opportunity is created, as the three countries are at varying levels of regional development in the field of energy communities, and the regional requirements and conditions differ significantly. A comprehensive investigation of the technical and economic viability of the ECs in the three regions is conducted on a simulation level. The technical simulation results show an increased self-consumption of individual users and the overall cell in all of the observed testbeds, while the economic analysis shows economic benefits at varying levels in each of the observed testbeds. The implemented R2EC system ascertains both technical and economic viability in the observed testbeds. KW - Energy Cells KW - Renewable energy KW - Energy Communities KW - Self-consumption Y1 - IS - 139 SP - 612 EP - 620 ER - TY - JOUR A1 - Lang, Moritz T1 - The mechanism of scale-invariance JF - Automatica N2 - A system is invariant with respect to an input transformation if we can transform any dynamic input by this function and obtain the same output dynamics after adjusting the initial conditions appropriately. Often, the set of all such input transformations forms a Lie group, the most prominent examples being scale-invariant (, ) and translational-invariant () systems, the latter comprising linear systems with transfer function zeros at the origin. Here, we derive a necessary and sufficient normal form for invariant systems and, by analyzing this normal form, provide a complete characterization of the mechanism by which invariance can be achieved. In this normal form, all invariant systems (i) estimate the applied input transformation by means of an integral feedback, and (ii) then apply the inverse of this estimate to the input before processing it in any other way. We demonstrate our results based on three examples: a scale-invariant “feed-forward loop”, a bistable switch, and a system resembling the core of the mammalian circadian network. KW - Invariant systems KW - Normal form KW - Adaptive systems KW - Transmission zeros Y1 - VL - 140 IS - June 2022 ER - TY - GEN A1 - Palme, Sebastian A1 - Kovacevic, Selma T1 - Creating spaces for collaborative learning in Moodle N2 - The current shift in teaching and learning away from the physical classroom to blended and digital learning environments presents many challenges and opportunities for both teachers and learners. A somewhat overlooked aspect of this transition concerns the issue of student collaboration in blended learning situations. Students teaming up to improve their learning process, exchange ideas and achieve learning goals has been an integral part of the higher education experience for many, while also strengthening students social skills. With the physical distancing and accompanying shift to increased online learning settings of the past few years, establishing this collaboration between students has become more and more difficult. Well-conceived digital social learning spaces and opportunities might be a way to compensate for these missed out traditional learning situations with peers in or after class. Going beyond typical group work activities teachers often utilize in their classes, Moodle offers a wide variety of opportunities for teachers to design these digital learning spaces tailored to the specific needs and objectives of their classes and students. Following a student-centred learning paradigm and a conception of the teacher as a designer and enabler of learning opportunities, we want to present a few use cases of Moodle activities, plugins and integrated tools suitable for designing these social spaces online. Among others we would like to showcase possible scenarios for peer assessments, open video conferencing rooms for students with BigBlueButton, collaborative test preparation with StudentQuiz, and connecting learners through a creative usage of the database activity. Picking up these different resources, we hope to motivate and inspire educators to design and roll out collaborative online spaces for their students to enable better teamwork and achieve deeper learning. KW - Moodle KW - student collaboration Y1 - 2023 ER - TY - CHAP A1 - Wala, Thomas A1 - Salmen, Christine T1 - Entrepreneurship Education and Innovation Transfer Through Student Practice Projects T2 - Mobility for Smart Cities and Regional Development - Challenges for Higher Education. ICL 2021. Lecture Notes in Networks and Systems, Vol. 390 N2 - Entrepreneurs keep the economy and society going by implementing new ideas. Entrepreneurship competencies such as creativity, risk tolerance or perseverance do not only emerge in professional life, but are already developed in early phases of socialization. Entrepreneurship education with its strongly action-oriented teaching and learning formats plays a triggering and process-reinforcing role in this respect. However, the competencies acquired through entrepreneurship education are also increasingly important for successful action in dependent employment. This article first shows that the goals and means of Entrepreneurship Education harmonize with the high practical relevance of teaching required by the Austrian Universities of Applied Sciences Act. Against this background, a concrete example of implementation is used to illustrate how the curricular anchoring of a student project in an engineering course can promote not only the practical relevance of teaching, but also the teaching of entrepreneurial competencies and the transfer of innovation between the university and industry. KW - Entrepreneurship education KW - Student practice projects KW - Knowledge transfer KW - University teaching Y1 - 2022 SN - 978-3-030-93906-9 SP - 858 EP - 868 PB - Springer CY - Cham ER - TY - RPRT A1 - Lünenborg, Yasmin Ruth A1 - Lanickova, Katerina A1 - Preusche, Ingrid T1 - Implementierung eines didaktischen Konzepts in sämtliche Bachelor-Lehrveranstaltungen der FHTW für mehr Lehr-/Lernqualität T2 - e-teaching.org KW - Didaktik KW - Hochschule Y1 - ER - TY - JOUR A1 - Wala, Thomas A1 - Baumüller, Josef T1 - Wie sinnvoll ist eine Übergewinnsteuer? JF - SWK KW - Übergewinnsteuer Y1 - 2022 IS - 26 SP - 1018 EP - 1023 ER - TY - JOUR A1 - Wala, Thomas T1 - Die betriebswirtschaftliche Klausur: Rechnungswesen und Controlling JF - WISU KW - Rechnungswesen KW - Controlling Y1 - 2022 VL - 2 SP - 198 EP - 200 ER - TY - JOUR A1 - Wala, Thomas T1 - Die betriebswirtschaftliche Klausur: Kostenmanagement. JF - WISU KW - Kostenmanagement Y1 - 2022 IS - 6 SP - 686 EP - 688 ER - TY - BOOK A1 - Wala, Thomas A1 - Haslehner, Franz A1 - Hirsch, Manuela T1 - Kostenrechnung, Budgetierung und Kostenmanagement KW - Kostenrechnung KW - Kostenmanagement Y1 - SN - 9783714303117 PB - Linde CY - Wien ER - TY - JOUR A1 - Wala, Thomas A1 - Baumüller, Josef T1 - Die Endfassung der Corporate Sustainability Reporting Directive – Neue Maßstäbe für die nachhaltige Unternehmensführung JF - GRC aktuell KW - Unternehmensführung KW - Nachhaltigkeit Y1 - 2022 IS - 3 SP - 87 EP - 91 PB - Linde ER - TY - JOUR A1 - Hagauer, Josef A1 - Matlschweiger, Ulrich A1 - Tippelreither, Christian A1 - Lutz, Markus A1 - Hribernig, Thomas A1 - Lackner, Maximilian T1 - Controlling Metal Fires through Cellulose Flake Blanketing Followed by Water Spray Cooling JF - Fire N2 - The traditional methods of fighting metal fires are not always safe for firefighters. The sand and salts that are thrown onto the fire to suffocate the flames can lead to splashes of molten metal, putting the firefighters and the surroundings at risk. A novel process is described where magnesium fires are brought under control using a simple two-step process. First, coated cellulose flakes, which contain approx. 30% inorganic salts, are blown onto the fire from a distance of several meters. Due to its low bulk density, the material settles smoothly on the fire and immediately covers the flames for several seconds. Before the hot metal can break through this cover, a fine water spray is applied to the fire. The water spray wets the top layer of the cellulose flakes, which will begin to char from the bottom. The water evaporates from within the cellulose flake layer and withdraws heat. It was observed that no hydrogen is formed and that this technique can safely control fires. It is judged that 90 kg of flakes could safely bring a pile of 75 kg of burning Mg flakes under control. By using a pneumatic conveying unit for the flakes, firefighters can effectively and efficiently cover the flames from a safe distance. This novel method could be recommended to firefighters in industrial magnesium processing plants, as well as local firefighters in the vicinity of such plants. KW - magnesium fire KW - metal fire KW - suffocation Y1 - U6 - http://dx.doi.org/10.3390/fire5030083 VL - 5 IS - 3 ER - TY - JOUR A1 - Diler, Abdulkerim A1 - Yanar, Mete A1 - Özdemir, Veysel Fatih A1 - Aydin, Recep A1 - Kaynar, Özgür A1 - Palangi, Valiollah A1 - Lackner, Maximilian A1 - Koçyigit, Rıdvan T1 - Effects of Slaughter Age of Holstein Friesian Bulls on Meat Quality: Chemical Composition, Textural Characteristics, Sensory Attributes and Fatty Acid Profile JF - Foods N2 - This study aimed to investigate the effects of slaughter age (young vs. old), muscle type (Longissimus dorsi (LD), Gluteus medius (GM)) and fat deposits (kidney knob and channel fat, subcutaneous fat, intramuscular fat) on chemical, organoleptic, textural characteristics and fatty acid composition of Holstein Friesian bull meat. For this purpose, the carcasses of 26 Holstein Friesian bulls that had been fattened on the same private farm were assigned to two experimental groups based on their age at slaughter: a young group (YG) (average age: 17.0 ± 1.0 months old) and an old group (OG) (average age: 22.0 ± 1.0 months old). The percentage of crude protein, panel tenderness score, polyunsaturated fatty acid (PUFA) and saturated fatty acid (SFA) content, the PUFA/SFA ratio and the hypocholesterolemic fatty acid (DFA)/hypercholesterolemic fatty acid (OFA) ratio of the bull carcasses decreased significantly with increasing slaughter age. By contrast, the OFA content of the carcasses significantly increased (p < 0.05) with increasing slaughter age. Advanced slaughter age resulted in lower panel tenderness scores. Additionally, the meat of the bulls in the OG was considered to be less healthy because of the less desirable fatty acid composition and nutritional indices, such as the PUFA/SFA and hypocholesterolemic/hypercholesterolemic ratios, compared to the meat from the bulls in the YG. Furthermore, the intramuscular fat and internal fat contained high percentages of PUFA and SFA and high PUFA/SFA and hypocholesterolemic/hypercholesterolemic ratios. Interestingly, the percentage of OFA content in the internal and intramuscular fat tissues decreased with increasing slaughter age. In conclusion, this study provided evidence that slaughter age and muscle and fat type are essential sources of variations in the textural characteristics, sensory panel attributes and fatty acid profile of meat from Holstein Friesian bulls. KW - fatty acid profile KW - sensory evaluation KW - slaughter age KW - texture profile analysis Y1 - U6 - http://dx.doi.org/10.3390/foods12010158 VL - 12 IS - 1 ER - TY - JOUR A1 - Bağcık, Caner A1 - Koç, Fisun A1 - Erten, Kadir A1 - Esen, Selim A1 - Palangi, Valiollah A1 - Lackner, Maximilian T1 - Lentilactobacillus buchneri Preactivation Affects the Mitigation of Methane Emission in Corn Silage Treated with or without Urea JF - Fermentation N2 - The aim of this study was to investigate the effect of different forms of Lentilactobacillus buchneri on the in vitro methane production, fermentation characteristics, nutritional quality, and aerobic stability of corn silage treated with or without urea. The following treatments were applied prior to ensiling: (1) no urea treatment and LB; (2) no urea treatment+freeze dried LB; (3) no urea treatment+preactivated LB; (4) with urea treatment+no LB; (5) with urea treatment+freeze dried LB; (6) with urea treatment+preactivated. LB was applied at a rate of 3 × 108 cfu/kg on a fresh basis, while urea was applied at a rate of 1% on the basis of dry matter. Data measured at different time points were analyzed according to a completely randomized design, with a 2 × 3 × 5 factorial arrangement of treatments, while the others were analyzed with a 2 × 3 factorial arrangement. Preactivated LB was more effective than freeze-dried LB in reducing silage pH, ammonia nitrogen, cell-wall components, yeast count, and carbon dioxide production, as well as increasing lactic acid and residual water-soluble carbohydrate and aerobic stability (p < 0.0001). A significant reduction in the methane ratio was observed after 24 h and 48 h incubation with preactivated forms of LB (p < 0.001). The results indicated that preactivated LB combined with urea improved fermentation characteristics, nutritional quality, and aerobic stability and reduced the methane ratio of corn silages. KW - gas production KW - Lentilactobacillus buchneri KW - methane KW - silage KW - urea Y1 - U6 - http://dx.doi.org/10.3390/fermentation8120747 VL - 8 IS - 12 ER - TY - CHAP A1 - Braun, Robert A1 - Lee, Barbara A1 - Rohatsch, Lukas T1 - Governance challenges of urban dataspace - transdisciplinary perspectives T2 - Extended Abstracts EU-SPRI Conference 2022 KW - Urban Data Space KW - Mobility KW - Governance Y1 - SP - 105 EP - 107 ER - TY - GEN A1 - Rohatsch, Lukas T1 - Technical perspective of Data Spaces KW - Data Spaces KW - FIWARE KW - iSHARE KW - i4TRUST KW - nGAIA-X Y1 - ER - TY - JOUR A1 - Palangi, Valiollah A1 - Taghizadeh, Akbar A1 - Abachi, Soheila A1 - Lackner, Maximilian T1 - Strategies to Mitigate Enteric Methane Emissions in Ruminants: A Review JF - Sustainability N2 - Methane is the main greenhouse gas (GHG) emitted by ruminants. Mitigation strategies are required to alleviate this negative environmental impact while maintaining productivity and ruminants’ health. To date, numerous methane mitigation strategies have been investigated, reported and suggested by scientists to the livestock industry. In this review, the authors will focus on the commonly practiced and available techniques expanding the knowledge of the reader on the advances of methane mitigation strategies with a focus on the recent literature. Furthermore, the authors will attempt to discuss the drawbacks of the strategies in terms of animal health and performance reduction as well as the concept of feed and energy loss, adding an economic perspective to methane emission mitigation which is in the farmers’ direct interest. As a whole, many factors are effective in reducing undesired methane production, but this is definitely a complex challenge. Conclusively, further research is required to offer effective and efficient methane production mitigation solutions in ruminants worldwide, thus positively contributing to climate change. KW - greenhouse gas (GHG) KW - ruminal microorganism KW - methane emission Y1 - U6 - http://dx.doi.org/10.3390/su142013229 VL - Vol. 14 IS - Issue 20 ER - TY - JOUR A1 - Mokhtarzadeh, Shakir A1 - Nobakht, Ali A1 - Mehmannavaz, Yousef A1 - Palangi, Valiollah A1 - Eseceli, Hüseyin A1 - Lackner, Maximilian T1 - Impacts of Continuous and Intermittent Use of Bovine Colostrum on Laying Japanese Quails: Egg Performance and Traits, Blood Biochemical and Antioxidant Status JF - Animals N2 - Quail is used in cookery, but mainly for its egg production around the globe, and sustainable poultry farming practices have been searched. The use of colostrum (beestings or first milk from cows) in quails’ diet can play an important role in providing probiotics and reducing the need for antibiotics, which, in addition to better quail performance, is effective in reducing environmental impacts. The results of the current research show that the continuous use of bovine colostrum (BC) in laying quails’ diets has beneficial effects on their performance, egg traits, blood indexes and antioxidant status. KW - antioxidant KW - blood parameters KW - carcass characteristics KW - egg traits Y1 - U6 - http://dx.doi.org/10.3390/ani12202811 VL - 12 IS - Issue 20 ER - TY - JOUR A1 - Palangi, Valiollah A1 - Lackner, Maximilian T1 - Management of Enteric Methane Emissions in Ruminants Using Feed Additives: A Review JF - Animals N2 - Methane emission from enteric fermentation in ruminants is the single most relevant greenhouse gas source in agriculture, and it is amongst the largest anthropogenic ones. As ruminants are needed globally for meat, milk and other goods production on a huge scale, feed additives could offer an interesting solution to reduce CH4 emissions. Methane emission strategies are investigated to maintaining productivity and the overall health of the animal. Some strategies have shown to reduce the propagation and/or eliminate ruminal flora affecting the health and productivity of the animal. Therefore, identifying beneficial strategies leads to improving productivity and the health of the animal and environment. KW - greenhouse gas KW - methane emission KW - ruminants Y1 - U6 - http://dx.doi.org/10.3390/ani12243452 VL - 12 IS - 24 ER - TY - CHAP A1 - Rauh, Sebastian A1 - Orsolits, Horst T1 - Perspectives on Virtual Reality in Higher Education for Robotics and Related Engineering Disciplines T2 - Robotics in Education (International Conference on Robotics in Education) N2 - Industrial engineering education has a strong focus on and affinity towards technology. While Virtual Reality hardware and applications advance and learning behaviour changes, it is particularly interesting to determine the possible use of Virtual Reality for teaching engineering subjects, for example fundamentals of robotics. This paper presents a study which examines the possible use of Virtual Reality learning environments at higher learning institutions. The study shows perspectives of students and lecturers and identifies opportunities and challenges for the use of Virtual Reality in industrial engineering education. The results of the indicated study show that the participants have a positive attitude towards Virtual Reality and strong motivation for in class use. The study results also suggest, that Virtual Reality content creation should be included in engineering curricula. KW - Virtual reality KW - Industrial engineering education KW - User study KW - The state of virtual reality Y1 - SN - 978-3-031-12848-6 SP - 39 EP - 51 PB - Springer ER - TY - CHAP A1 - Lietze, Stefanie A1 - Sagmeister, Nicole ED - Pauschenwein, Jutta ED - Hernády, Birgit ED - Michelitsch, Linda T1 - Die sind eh auch mitgemeint! Hochschulkommunikation analysieren und inkludierender gestalten T2 - Tagungsband zum 21. E-Learning Tag der FH JOANNEUM am 21.09.2022 N2 - Hochschulen und Studiengänge sprechen Studieninteressierte nicht bevölkerungsrepräsentativ an. Nach einem kurzen Abriss der aktuellen Lage und der Diversitätsdimensionen werden anhand einer adaptierten Form der „4R- Methode“ des Gender-Mainstreamings Kommunikationsarten, -medien und -ebenen mit Blick auf Kommunizierende und Kontexte beleuchtet. Dieser Beitrag soll Hochschulen und Studiengängen einen einfachen Leitfaden an die Hand geben, die eigene Sprache auf den verschiedenen Kommunikationskanälen kritisch zu reflektieren und inkludierender zu gestalten, um Stereotypisierung zu vermeiden und alle anzusprechen KW - Equality KW - inkludierende Sprache KW - Gender-Stereotype Y1 - SN - 978-3-903318-08-3 SP - 24 EP - 36 PB - Verlag der FH JOANNEUM Gesellschaft mbH CY - Graz ER - TY - JOUR A1 - Pasteka, Richard A1 - Schöllbauer, Lara Alina A1 - Santos da Costa, Joao Pedro A1 - Kolar, Radim A1 - Forjan, Mathias T1 - Experimental Evaluation of Dry Powder Inhalers During In- and Exhalation Using a Model of the Human Respiratory System (xPULM™) JF - Pharmaceutics N2 - Dry powder inhalers are used by a large number of patients worldwide to treat respiratory diseases. The objective of this work is to experimentally investigate changes in aerosol particle diameter and particle number concentration of pharmaceutical aerosols generated by four dry powder inhalers under realistic inhalation and exhalation conditions. To simulate patients undergoing inhalation therapy, the active respiratory system model (xPULM™) was used. A mechanical upper airway model was developed, manufactured, and introduced as a part of the xPULM™ to represent the human upper respiratory tract with high fidelity. Integration of optical aerosol spectrometry technique into the setup allowed for evaluation of pharmaceutical aerosols. The results show that there is a significant difference (p < 0.05) in mean particle diameter between inhaled and exhaled particles with the majority of the particles depositing in the lung, while particles with the size of (>0.5 μm) are least influenced by deposition mechanisms. The fraction of exhaled particles ranges from 2.13% (HandiHaler®) over 2.94% (BreezHaler®), and 6.22% (Turbohaler®) to 10.24% (Ellipta®). These values are comparable to previously published studies. Furthermore, the mechanical upper airway model increases the resistance of the overall system and acts as a filter for larger particles (>3 μm). In conclusion, the xPULM™ active respiratory system model is a viable option for studying interactions of pharmaceutical aerosols and the respiratory tract regarding applicable deposition mechanisms. The model strives to support the reduction of animal experimentation in aerosol research and provides an alternative to experiments with human subjects. KW - Biomedical Engineering KW - Dry powder inhaler resistance KW - optical aerosol spectrometry KW - mechanical upper airway model KW - inspiratory flow rate Y1 - 2022 VL - 2022 IS - 14/3 ER - TY - JOUR A1 - Grasel, Bernhard A1 - Baptista, José A1 - Tragner, Manfred T1 - Supraharmonic and Harmonic Emissions of a Bi-Directional V2G Electric Vehicle Charging Station and Their Impact to the Grid Impedance JF - Energies N2 - Bidirectional electric vehicle supply equipment and charging stations (EVSE) offer new business models and can provide services to the electrical grid. The smart grid lab in Vienna gives unique testing possibilities of future smart grids, as different type of electrical equipment can be operated at a reconstructed, well-known distribution grid. In this work the harmonic and supraharmonic emissions of a bidirectional EVSE are measured according to IEC61000-4-7 and IEC61000-4-30 Ed3 standard as well as the high-frequency grid impedance. In addition, the efficiency and the power factor are determined at various operating points. Although THDi at nominal power (10 kW) is very low and the efficiency and power factor is very high, at low power levels the opposite situation arise. Supraharmonic emissions remain stable independent of the charging/discharging power, and both wideband and narrowband emissions occur. The additional capacitance when connecting the EVSE impacts the high-frequency grid impedance substantially and generates resonance points. KW - power quality KW - V2G KW - supraharmonics Y1 - U6 - http://dx.doi.org/10.3390/en15082920 VL - 15 IS - 8 ER - TY - JOUR A1 - Wöber, Wilfried A1 - Mehnen, Lars A1 - Curto, Manuel A1 - Dias Tibihika, Papius A1 - Tesfaye, Genanaw A1 - Meimberg, Harald T1 - Investigating Shape Variation Using Generalized Procrustes Analysis and Machine Learning JF - Applied Sciences N2 - Abstract: The biological investigation of a population’s shape diversity using digital images is typi- cally reliant on geometrical morphometrics, which is an approach based on user-defined landmarks. In contrast to this traditional approach, the progress in deep learning has led to numerous applications ranging from specimen identification to object detection. Typically, these models tend to become black boxes, which limits the usage of recent deep learning models for biological applications. However, the progress in explainable artificial intelligence tries to overcome this limitation. This study compares the explanatory power of unsupervised machine learning models to traditional landmark-based approaches for population structure investigation. We apply convolutional autoencoders as well as Gaussian process latent variable models to two Nile tilapia datasets to investigate the latent structure using consensus clustering. The explanatory factors of the machine learning models were extracted and compared to generalized Procrustes analysis. Hypotheses based on the Bayes factor are formulated to test the unambiguity of population diversity unveiled by the machine learning models. The findings show that it is possible to obtain biologically meaningful results relying on unsupervised machine learning. Furthermore we show that the machine learning models unveil latent structures close to the true population clusters. We found that 80% of the true population clusters relying on the convolutional autoencoder are significantly different to the remaining clusters. Similarly, 60% of the true population clusters relying on the Gaussian process latent variable model are significantly different. We conclude that the machine learning models outperform generalized Procrustes analysis, where 16% of the population cluster was found to be significantly different. However, the applied machine learning models still have limited biological explainability. We recommend further in-depth investigations to unveil the explanatory factors in the used model. Keywords: generalized procrustes analysis; machine learning; convolutional autoencoder; Gaussian process latent variable models KW - generalized procrustes analysis KW - machine learning KW - convolutional autoencoder KW - Gaussian process latent variable models Y1 - VL - 2022 IS - 12(6), 3158 ER - TY - JOUR A1 - Zhang, Hang A1 - Yao, Yuan A1 - Ma, Yingxin A1 - Lackner, Maximilian A1 - Jiang, Yunliang T1 - A 3D printing tool-path generation strategy based on the partition of principal stress field for fused filament fabrication JF - The International Journal of Advanced Manufacturing Technology N2 - In order to enhance the strength of 3D-printed parts made of polymer materials and reduce the anisotropy caused by the fused filament fabrication process, this paper proposes an inter-layer interleaved composite path planning method based on the directional partition of the principal stress field. This method not only ensures intra-layer reinforcement under specific working conditions but also increases the strength of the printed part by enhancing the adhesion of adjacent layers through staggered filling between layers. The mechanical performance is improved by 10 to 30% compared to other conventional filling patterns such as the zigzag filling algorithm. Inter-layer interleaved composite enhancement path planning method is suitable for path planning of structures with complex shapes and is easily integrated into existing general computer-aided engineering processes. KW - Principal stress field KW - Anisotropy strength KW - Clustering Y1 - IS - 122 SP - 1719 EP - 1735 ER - TY - JOUR A1 - Yalcin, Faruk A1 - Himmelstoß, Felix T1 - Boost Converter based 3-phase AC-AC Active Tracking Voltage Regulator Controlled by a Robust Hybrid Control Method JF - Sakarya University Journal of Science KW - AC-AC regulator KW - active tracking KW - boost converter KW - three-phase KW - THD Y1 - VL - 2022 IS - 26(1) SP - 24 EP - 37 ER - TY - CHAP A1 - Widhalm, Dominik A1 - Goeschka, Karl M. A1 - Kastner, Wolfgang T1 - Undervolting on wireless sensor nodes: a critical perspective T2 - Proceedings of the 23rd International Conference on Distributed Computing and Networking (ICDCN 2022), 4-7 January 2022, Delhi, India KW - wireless sensor network KW - wireless sensor node KW - undervolting KW - energy efficiency KW - faults Y1 - U6 - http://dx.doi.org/https://doi.org/10.1145/3491003.3491018 ER - TY - CHAP A1 - Mehnen, Lars A1 - Pohn, Birgit A1 - Blaickner, Matthias A1 - Mandl, Thomas A1 - Dregely, Isabel T1 - Teaching & Learning Analytics for Data-Based Optimization of Teaching and Learning Processes in Courses with Blended Learning T2 - 2022 International Conference on Software, Telecommunications and Computer Networks (SoftCOM), 2022 N2 - Learning Management Systems (LMS), such as Moodle, enable the rapid progress of digitisation in teaching, which is no longer only taking place in the lecture hall, but increasingly “online” and asynchronously. New didactic concepts (blended learning, “flipped classroom”) consist of alternating self-learning and face-to-face phases, with the former taking place in the LMS, i.e. online. However, no analysis has yet been carried out as to how students act with the material in the self-learning phase, or the teachers are not provided with any information about the learning progress of the students during the self-learning phase. In this paper, concepts of learning and teaching analytics are presented to answer these questions and to integrate the measures derived from them into the teaching processes in a sustainable manner. KW - teaching analytics KW - learning analytics KW - learning management systems KW - artificial intelligence KW - Learning management systems Y1 - 2022 SN - 978-953-290-117-7 PB - IEEE ER - TY - JOUR A1 - Heinzel, Johannes Christoph A1 - Oberhauser, Viola A1 - Keibl, Claudia A1 - Schädl, Barbara A1 - Swiadek, Nicole V. A1 - Längle, Gregor A1 - Frick, Helen A1 - Slezak, Cyrill A1 - Prahm, Cosima A1 - Grillari, Johannes A1 - Kolbenschlag, Jonas A1 - Hercher, David T1 - ESWT Diminishes Axonal Regeneration following Repair of the Rat Median Nerve with Muscle-In-Vein Conduits but Not after Autologous Nerve Grafting JF - Biomedicines N2 - Investigations reporting positive effects of extracorporeal shockwave therapy (ESWT) on nerve regeneration are limited to the rat sciatic nerve model. The effects of ESWT on muscle-in-vein conduits (MVCs) have also not been investigated yet. This study aimed to evaluate the effects of ESWT after repair of the rat median nerve with either autografts (ANGs) or MVCs. In male Lewis rats, a 7 mm segment of the right median nerve was reconstructed either with an ANG or an MVC. For each reconstructive technique, one group of animals received one application of ESWT while the other rats served as controls. The animals were observed for 12 weeks, and nerve regeneration was assessed using computerized gait analysis, the grasping test, electrophysiological evaluations and histological quantification of axons, blood vessels and lymphatic vasculature. Here, we provide for the first time a comprehensive analysis of ESWT effects on nerve regeneration in a rat model of median nerve injury. Furthermore, this study is among the first reporting the quantification of lymphatic vessels following peripheral nerve injury and reconstruction in vivo. While we found no significant direct positive effects of ESWT on peripheral nerve regeneration, results following nerve repair with MVCs were significantly inferior to those after ANG repair. KW - Tissue Engineering KW - Muscle-In-Vein Conduits KW - Axonal Regeneration KW - Autologous Nerve Grafting Y1 - VL - 2022 IS - 10(8) SP - 1777 ER - TY - JOUR A1 - Himmelstoß, Felix T1 - Improved positive output voltage super-lift Boost converter JF - WSEAS TRANSACTIONS on POWER SYSTEMS KW - DC/DC converter KW - feedforward control KW - boost converter KW - simulation Y1 - VL - 2022 IS - Vol. 17 SP - 68 EP - 75 ER - TY - JOUR A1 - Strohmeier, Karin A1 - Hofmann, Martina A1 - Jacak, Jaroslaw A1 - Narzt, Marie-Sophie A1 - Wahlmueller, Marlene A1 - Mairhofer, Mario A1 - Schädl, Barbara A1 - Holnthoner, Wolfgang A1 - Barsch, Martin A1 - Sandhofer, Matthias A1 - Wolbank, Susanne A1 - Priglinger, Eleni T1 - Multi-Level Analysis of Adipose Tissue Reveals the Relevance of Perivascular Subpopulations and an Increased Endothelial Permeability in Early-Stage Lipedema JF - Biomedicines N2 - Lipedema is a chronic, progressive disease of adipose tissue with unknown etiology. Based on the relevance of the stromal vascular fraction (SVF) cell population in lipedema, we performed a thorough characterization of subcutaneous adipose tissue, SVF isolated thereof and the sorted populations of endothelial cells (EC), pericytes and cultured adipose-derived stromal/stem cells (ASC) of early-stage lipedema patients. We employed histological and gene expression analysis and investigated the endothelial barrier by immunofluorescence and analysis of endothelial permeability in vitro. Although there were no significant differences in histological stainings, we found altered gene expression of factors relevant for local estrogen metabolism (aromatase), preadipocyte commitment (ZNF423) and immune cell infiltration (CD11c) in lipedema on the tissue level, as well as in distinct cellular subpopulations. Machine learning analysis of immunofluorescence images of CD31 and ZO-1 revealed a morphological difference in the cellular junctions of EC cultures derived from healthy and lipedema individuals. Furthermore, the secretome of lipedema-derived SVF cells was sufficient to significantly increase leakiness of healthy human primary EC, which was also reflected by decreased mRNA expression of VE-cadherin. Here, we showed for the first time that the secretome of SVF cells creates an environment that triggers endothelial barrier dysfunction in early-stage lipedema. Moreover, since alterations in gene expression were detected on the cellular and/or tissue level, the choice of sample material is of high importance in elucidating this complex disease. KW - Tissue Engineering KW - Adipose Tissue KW - Lipedema KW - Endothelial Cells Y1 - VL - 2022 IS - 10(5) SP - 1163 ER - TY - CHAP A1 - Krizek, Gerd Christian A1 - Langer, Karin A1 - Leitgeb, Erich A1 - Seyringer, Dana A1 - Schreivogl, Paul A1 - Grabher-Meyer, Arno T1 - Educational Activities with Photonics Explorer T2 - 2022 International Conference on Broadband Communications for Next Generation Networks and Multimedia Applications (CoBCom) N2 - In this paper we present various educational activities with Photonics Explorer, an educational kit developed by the photonics research team B - PHOT at VUB (Vrije Universiteit Brussel) for students at secondary schools. The concept is a ‘lab-in-a-box’ that enables students of the 2 nd and 3 rd grade to do photonics experiments themselves at school with lasers, LEDs, lenses, optical fibers, and other high-tech components. Even though, the kit was developed for the secondary schools, we use experiments from the kit also for some other teaching activities such as lectures at the university, photonics workshops for teachers and children at primary/secondary schools or for events such as children's/youth's university or the night of sciences. In the frame of Austrian based project Phorsch! we have organized most of these activities which will be presented here. KW - education KW - photonics Y1 - PB - IEEE ER - TY - JOUR A1 - Trisko, Johanna A1 - Fleck, Johanna A1 - Kau, Silvio A1 - Oesterreicher, Johannes A1 - Holnthoner, Wolfgang T1 - Lymphatic and Blood Endothelial Extracellular Vesicles: A Story Yet to Be Written JF - Life N2 - Extracellular vesicles (EVs), such as exosomes, microvesicles, and apoptotic bodies, are cell-derived, lipid bilayer-enclosed particles mediating intercellular communication and are therefore vital for transmitting a plethora of biological signals. The vascular endothelium substantially contributes to the circulating particulate secretome, targeting important signaling pathways that affect blood cells and regulate adaptation and plasticity of endothelial cells in a paracrine manner. Different molecular signatures and functional properties of endothelial cells reflect their heterogeneity among different vascular beds and drive current research to understand varying physiological and pathological effects of blood and lymphatic endothelial EVs. Endothelial EVs have been linked to the development and progression of various vascular diseases, thus having the potential to serve as biomarkers and clinical treatment targets. This review aims to provide a brief overview of the human vasculature, the biology of extracellular vesicles, and the current knowledge of endothelium-derived EVs, including their potential role as biomarkers in disease development. KW - Tissue Engineering KW - Endothelial Cells KW - vascularization KW - extracellular vesicles KW - lymphatic endothelial cells Y1 - VL - 2022 IS - 12(5) SP - 654 ER - TY - JOUR A1 - Sayer, Simon A1 - Zandrini, Tommaso A1 - Markovic, Marica A1 - Van Hoorick, Jasper A1 - Van Vlierberghe, Sandra A1 - Baudis, Stefan A1 - Holnthoner, Wolfgang A1 - Ovsianikov, Aleksandr T1 - Guiding cell migration in 3D with high-resolution photografting JF - Scientific Reports N2 - Multi-photon lithography (MPL) has proven to be a suitable tool to precisely control the microenvironment of cells in terms of the biochemical and biophysical properties of the hydrogel matrix. In this work, we present a novel method, based on multi-photon photografting of 4,4′-diazido-2,2′-stilbenedisulfonic acid (DSSA), and its capabilities to induce cell alignment, directional cell migration and endothelial sprouting in a gelatin-based hydrogel matrix. DSSA-photografting allows for the fabrication of complex patterns at a high-resolution and is a biocompatible, universally applicable and straightforward process that is comparably fast. We have demonstrated the preferential orientation of human adipose-derived stem cells (hASCs) in response to a photografted pattern. Co-culture spheroids of hASCs and human umbilical vein endothelial cells (HUVECs) have been utilized to study the directional migration of hASCs into the modified regions. Subsequently, we have highlighted the dependence of endothelial sprouting on the presence of hASCs and demonstrated the potential of photografting to control the direction of the sprouts. MPL-induced DSSA-photografting has been established as a promising method to selectively alter the microenvironment of cells. KW - Tissue Engineering KW - Cell migration KW - photografting Y1 - VL - 2022 IS - 12(1), 10196 SP - 8626 ER - TY - JOUR A1 - Hromada, Carina A1 - Hartmann, Jaana A1 - Oesterreicher, Johannes A1 - Stoiber, Anton A1 - Daerr, Anna A1 - Schädl, Barbara A1 - Priglinger, Eleni A1 - Teuschl-Woller, Andreas H. A1 - Holnthoner, Wolfgang A1 - Heinzel, Johannes Christoph A1 - Hercher, David T1 - Occurrence of Lymphangiogenesis in Peripheral Nerve Autografts Contrasts Schwann Cell-Induced Apoptosis of Lymphatic Endothelial Cells In Vitro JF - Biomolecules N2 - Peripheral nerve injuries pose a major clinical concern world-wide, and functional recovery after segmental peripheral nerve injury is often unsatisfactory, even in cases of autografting. Although it is well established that angiogenesis plays a pivotal role during nerve regeneration, the influence of lymphangiogenesis is strongly under-investigated. In this study, we analyzed the presence of lymphatic vasculature in healthy and regenerated murine peripheral nerves, revealing that nerve autografts contained increased numbers of lymphatic vessels after segmental damage. This led us to elucidate the interaction between lymphatic endothelial cells (LECs) and Schwann cells (SCs) in vitro. We show that SC and LEC secretomes did not influence the respective other cell types' migration and proliferation in 2D scratch assay experiments. Furthermore, we successfully created lymphatic microvascular structures in SC-embedded 3D fibrin hydrogels, in the presence of supporting cells; whereas SCs seemed to exert anti-lymphangiogenic effects when cultured with LECs alone. Here, we describe, for the first time, increased lymphangiogenesis after peripheral nerve injury and repair. Furthermore, our findings indicate a potential lymph-repellent property of SCs, thereby providing a possible explanation for the lack of lymphatic vessels in the healthy endoneurium. Our results highlight the importance of elucidating the molecular mechanisms of SC-LEC interaction. KW - Tissue Engineering KW - peripheral nerve regeneration KW - lymphangiogenesis KW - Schwann cells KW - lymphatic endothelial cells Y1 - VL - 2022 IS - 12, 6 SP - 820 ER - TY - JOUR A1 - Lauer, Henrik A1 - Prahm, Cosima A1 - Thiel, Johannes Tobias A1 - Kolbenschlag, Jonas A1 - Daigeler, Adrien A1 - Hercher, David A1 - Heinzel, Johannes Christoph T1 - The Grasping Test Revisited: A Systematic Review of Functional Recovery in Rat Models of Median Nerve Injury JF - Biomedicines N2 - The rat median nerve model is a well-established and frequently used model for peripheral nerve injury and repair. The grasping test is the gold-standard to evaluate functional recovery in this model. However, no comprehensive review exists to summarize the course of functional recovery in regard to the lesion type. According to PRISMA-guidelines, research was performed, including the databases PubMed and Web of Science. Groups were: (1) crush injury, (2) transection with end-to-end or with (3) end-to-side coaptation and (4) isogenic or acellular allogenic grafting. Total and respective number, as well as rat strain, type of nerve defect, length of isogenic or acellular allogenic allografts, time at first signs of motor recovery (FSR) and maximal recovery grasping strength (MRGS), were evaluated. In total, 47 articles met the inclusion criteria. Group I showed earliest signs of motor recovery. Slow recovery was observable in group III and in graft length above 25 mm. Isografts recovered faster compared to other grafts. The onset and course of recovery is heavily dependent from the type of nerve injury. The grasping test should be used complementary in addition to other volitional and non-volitional tests. Repetitive examinations should be planned carefully to optimize assessment of valid and reliable data. KW - Tissue Engineering KW - Median Nerve Injury KW - Nerve Regeneration Y1 - VL - 2022 IS - 10(8) SP - 1878 ER - TY - THES A1 - Widhalm, Dominik T1 - Sensor Node Fault Detection in Wireless Sensor Networks: An Immune-inspired Approach KW - fault detection KW - sensor node KW - node-level diagnostics KW - wireless sensor network KW - anomaly detection Y1 - ER - TY - JOUR A1 - Himmelstoß, Felix A1 - Edelmoser, Karl T1 - Virtual three-phase laboratory exercise during pandemic situation JF - WSEAS TRANSACTIONS on ADVANCES in ENGINEERING EDUCATION KW - virtual laboratory KW - three-phase systems KW - phasor diagram KW - neutral line interruption KW - voltage displacement Y1 - VL - 2022 ER - TY - CHAP A1 - Himmelstoß, Felix A1 - Votzi, Helmut T1 - Modified d(2-d)/(1-d)2-Converter T2 - Proceedings of the Power Conversion and Intelligent Motion Conference (PCIM) 2022, 10-12 May, 2022 Nurenberg, Germany KW - DC/DC converter KW - quadratic converter KW - modeling Y1 - U6 - http://dx.doi.org/doi: 10.30420/565822200 SP - 1446 EP - 1453 ER - TY - JOUR A1 - Yalcin, Faruk A1 - Himmelstoß, Felix T1 - Single-phase Boost-type Active Tracking AC-AC Voltage Regulator with an Improved Hybrid Control Technique JF - Duzce University Journal of Science and Technology KW - Boost converter KW - AC-AC regulator KW - Single-phase KW - Active tracking Y1 - VL - 2022 IS - 10, issue 1 SP - 139 EP - 153 ER - TY - JOUR A1 - Yalcin, Faruk A1 - Himmelstoß, Felix T1 - Three-phase Active Tracking AC-AC Voltage Regulator based on Buck Converter with an Efficient Hybrid Control Technique JF - Düzce University Journal of Science & Technology KW - buck converter KW - AC-AC regulator KW - active tracking KW - THD Y1 - VL - 2022 IS - 10 SP - 537 EP - 554 ER - TY - CHAP A1 - Giovagnola, Jessica A1 - Fernandez, Miguel Molina A1 - Beneder, Roman A1 - Schmitt, Patrick A1 - Pegalajar Cuellar, Manuel A1 - Morales Santos, Diego Pedro T1 - Multisensor Avionics Architecture for BVLOS Drone Services T2 - Journal of Physics: Conference Series ; 12th IEEE EASN International Conference EASN2022, Spain, Barcelona, Oct. 18-21, 2022 KW - Heterogeneous Sensor Fusion KW - Multicore Microcontroller KW - Artifical Intelligence KW - BVLOS Drone Services Y1 - U6 - http://dx.doi.org/10.1088/1742-6596/2526/1/012084 VL - Volume 2526 ER - TY - CHAP A1 - Dziech, Andrzej A1 - Wassermann, Jakob A1 - Windisch, Michael A1 - Baran, Remigiusz A1 - Zeja, Andrzej A1 - Bogacki, Piotr T1 - A New Approach to Enhance Learning Data Sets for Object Classification T2 - Proceedings of the International Conference on Circuits, Systems, Communications and Computers, Crete, Greece, July 19-22, 2022 KW - poor dataset quality KW - CNN KW - SVT KW - shape descriptor KW - incremental learning Y1 - U6 - http://dx.doi.org/https://doi.org/10.1109/CSCC55931.2022.00024 ER - TY - CHAP A1 - Eder, Gabriele A1 - Voronko, Yuliya A1 - Berger, Karl Anton A1 - Újvári, Gusztáv A1 - Knöbl, Karl A1 - Neumaier, Lukas T1 - UV-Fluoreszenz Bildanalyse zur frühzeitigen Detektion von PV-Leistungsdegradation T2 - Tagungsband der Österreichische Fachtagung für Photovoltaik und Stromspeicherung 2022 KW - Alterungstest KW - Ultraviolet Fluorescence KW - UVF Imaging KW - Lebendauerbestimmung Y1 - ER - TY - JOUR A1 - Himmelstoss, Felix T1 - Design of State-Space Controllers with the Help of Signal Flow Graphs Shown for a Buck Converter JF - WSEAS Transactions on Power Systems, Volume 21, 2022, pp. 421-429 KW - DC/DC converter KW - Buck converter KW - modelling KW - simulation KW - state space controller Y1 - U6 - http://dx.doi.org/10.37394/23202.2022.21.46 VL - Volume 21 SP - 421 EP - 429 ER - TY - JOUR A1 - Himmelstoss, Felix T1 - Third order converters with current output for driving LEDs JF - WSEAS Transactions on Power Systems KW - DC/DC converters KW - current output KW - limited duty cycle converter KW - simulation KW - modeling Y1 - U6 - http://dx.doi.org/10.37394/232016.2022.17.40 VL - Volume 17 SP - 402 EP - 409 ER - TY - CHAP A1 - Veigl, Christoph A1 - Klaus, Benjamin A1 - Aigner, Benjamin A1 - Wagner, Manuel T1 - Universal Access Panel: A Novel Approach for Accessible Smart Homes and IoT T2 - Computers Helping People with Special Needs / Proceedings of the 18th International Conference ICCHP-AAATE 2022, July 11-15, 2022, Lecco, Italy N2 - Although various standards and guidelines for accessible design exist, many modern digital devices lack even basic accessibility features. In particular, touchscreens without haptic feedback and a highly complex menu navigation impose serious hurdles for many people – especially for people with disabilities and elderly persons. In this work, we present the Universal Access Panel (UAP) for enabling barrier-free access to home appliances and IoT devices. The system offers a novel, radically simple, multimodal user interface consisting of just a few interaction elements for accessing dedicated functions of the connected home. Using established APIs and communication protocols such as HomeConnect or OpenHab, various domestic appliances, consumer products and smart home devices can be controlled from a single, multimodal interaction console. The system has been designed in cooperation with visually impaired accessibility experts and a user study was conducted with people from the target group. The results show a high overall usability of the prototype. KW - Home Appliances KW - Accessibility KW - Multimodal User Interface KW - Smart Homes KW - Internet-of-Things Y1 - U6 - http://dx.doi.org/https://doi.org/10.1007/978-3-031-08645-8_18 SP - 148 EP - 158 ER - TY - CHAP A1 - Himmelstoss, Felix A1 - Windisch, Michael T1 - Tapped inductor Boost with exploitation of the stray energy T2 - Proceedings of 2022 IEEE 20th International Power Electronics and Motion Control Conference (PEMC 2022), Brasov, Rumania, Sep. 25-29 N2 - Tapped inductor DC-to-DC converters are interesting circuits, the winding ratio of the two windings mounted on the same core change the voltage transformation ratio compared to the untapped inductor. The tapped inductor converters are especially useful, when high or low voltage transformation ratios have to be realized. The disadvantage of this concept is that the coupling between the two windings is not total and can be described by the stray or leakage inductance. This stray inductance leads to a high overvoltage at the active switch, and therefore also across other elements of the converter. After a short summery of the ideal tapped Boost converter, the design of an RCD snubber which limits the overvoltage is explained. To improve the efficiency of the converter two active snubber networks are treated, which feed the energy stored in the snubber capacitor into the input source or into the output circuit. Simulations are used to prove these considerations. KW - DC/DC converter KW - stray inductance KW - recuperation KW - active snubber Y1 - U6 - http://dx.doi.org/10.1109/PEMC51159.2022.9962849 SP - 75 EP - 80 ER - TY - CHAP A1 - Himmelstoss, Felix A1 - Votzi, Helmut T1 - Two-Stage Step-up Converter with Different Voltage Transformation Ratios depending on the Duty Cycle T2 - 20th International Conference on Renewable Energies and Power Quality (ICREPQ’22) Vigo (Spain), 27th to 29th July 2022 N2 - A two-stage converter with high output voltage ratio and reduced current stress of the inductors and partly reduced voltage stress is discussed. The function is explained with the help of voltage and current diagrams. The voltage transformation ratio changes between a quadratic step-up for duty cycles lower 0.5 and a double Boost converter for duty cycles higher than 0.5. Dimensioning hints, the control law for feed-forward controls, the transient when the supply is turned on is discussed and some simulations are given. A comparison to other two-stage converters is also treated. KW - Quadratic boost KW - double boost converter KW - feed-forward control KW - start-up Y1 - U6 - http://dx.doi.org/10.24084/repqj20.218 VL - Vol. 20 SP - 66 ER - TY - GEN A1 - Friedrich, Robin A1 - Lakic, Nevana A1 - Prähauser, Linda A1 - Schweitzer, Karoline A1 - Olscher, Christoph A1 - Monforte Vila, Xavier A1 - Leitner, Rita A1 - Gepp, Barbara T1 - Effects of Plastic on the Freshwater Snail Biomphalaria Glabrata T2 - SETAC Europe 32nd Annual Meeting in Copenhagen, Denmark from 15 - 19. May 2022 KW - Ecotoxicology KW - Biomphalaria Glabrata Y1 - ER - TY - CHAP A1 - Himmelstoss, Felix T1 - Cascaded control of a Buck converter designed and simulated with the help of LTSpice T2 - 6th International European Congress on Interdisciplinary Scientific Research, Aug. 26-27, 2022, Bukarest, Rumania KW - education KW - power electronics converters KW - Buck converter KW - two-loop control KW - cascade control Y1 - SP - 1086 EP - 1096 ER - TY - CHAP A1 - Himmelstoss, Felix A1 - Edelmoser, Karl T1 - Liquid and surface disinfection with pulsed UVC LEDs T2 - 2nd Ahi Evran International Conference on Scientific Research, Kirshehir, Turkey, October 21-23, 2022 KW - disinfection KW - light emitting diode KW - ultraviolet UV light KW - pulsed power KW - DC/DC Converter Y1 - SP - 654 EP - 664 ER - TY - CHAP A1 - Himmelstoss, Felix A1 - Yaman, Ferhat A1 - Edelmoser, Karl T1 - Building block for a spot welder T2 - International Congress on Innovation Technologies & Engineering, Sept. 2-4, 2022, Izmir, Turkey, pp. 139-148 KW - spot welding KW - capacitor charging KW - pulse power KW - retrofit Y1 - SP - 139 EP - 148 ER - TY - CHAP A1 - Himmelstoss, Felix T1 - Concept to change the voltage transformation ratio of a DC/DC converter T2 - Cukurova 9th International Scientific Researches Conference, Oct. 9-11, 2022, Adana, Turkey, pp. 258-273 KW - DC/DC converter KW - AC-Switch KW - voltage transformation ratio KW - modeling KW - simulation Y1 - SP - 258 EP - 273 ER - TY - CHAP A1 - Himmelstoss, Felix T1 - Three DC/DC Converters with continuous input and output current for LED applications T2 - International Conference on Engineering Sciences ICES, Baku, Azerbeijan, Nov. 11-12, 2022 KW - DC/DC converter KW - current control KW - efficiency KW - lighting Y1 - SP - 335 EP - 347 ER - TY - CHAP A1 - Himmelstoß, Felix T1 - Controller design of a Buck converter with the help of LTSpice T2 - Proceedings of the International Asian Congress of Contemporary Sciences, 27-29 May, 2022, Van, Turkiye KW - DC/DC converter KW - Buck converter KW - feedforward KW - compensation controller KW - simulation Y1 - SP - 195 EP - 202 ER - TY - CHAP A1 - Angel, Nikolaus A1 - Orsolits, Horst A1 - Garcia, Jose T1 - Developing an AR Based Tool for Teaching Motion Analysis on Assembly Tasks T2 - 2022 8th International Conference of the Immersive Learning Research Network (iLRN), 2022 N2 - Engineering education courses look into processes, equipment and people in order to prepare students to tackle problems in their careers. In manufacturing industry, it is important to use virtual manufacturing tools to analyse processes. This includes both equipment and people. Assembly operations can involve human operators. Modular arrangements of predetermined time standards MODAPTS is a predetermined motion time system method used to analyse assembly processes. Augmented reality (AR) is increasingly being used for industrial processes as well as in education. AR application have been used for maintenance training as a useful way to overly digital instructions to a trainee whilst being able to look at a real object. This is potential beneficial for education. This paper presents the evaluation of a prototype to test a predetermined time standards model using an AR application. An evaluation was carried out comparing AR-based instructions in tablet and PC monitor and paper-written instructions. The results of evaluating the prototype encourage their use as an educational tool in engineering courses. KW - Augmented Reality KW - Education Technology KW - Virtual Engineering KW - Assembly Assistance Y1 - SN - 978-1-7348-9952-8 U6 - http://dx.doi.org/10.23919/iLRN55037.2022.9815914 ER - TY - GEN A1 - Nemec, Iris A1 - Frohner, Matthias T1 - How can life science students, especially biomedical engineering students, benefit from the extra-curricular offerings and systems already established in other scientific fields? T2 - Abstracts of the 2022 Joint Annual Conference of the Austrian (ÖGBMT), German (VDE DGBMT) and Swiss (SSBE) Societies for Biomedical Engineering, including the 14th Vienna International Workshop on Functional Electrical Stimulation KW - extra-curricular offerings KW - education Y1 - U6 - http://dx.doi.org/https://doi.org/10.1515/bmt-2022-2001 SP - 348 ER - TY - GEN A1 - Traxler, Lukas A1 - Balz, Andrea T1 - Current Advances in the Optical Characterization of Intraocular Lenses T2 - Abstracts of the 2022 Joint Annual Conference of the Austrian (ÖGBMT), German (VDE DGBMT) and Swiss (SSBE) Societies for Biomedical Engineering, including the 14th Vienna International Workshop on Functional Electrical Stimulation KW - Intraocular Lenses Y1 - U6 - http://dx.doi.org/https://doi.org/10.1515/bmt-2022-2001 SP - 102 ER - TY - JOUR A1 - Ashmwe, Mohamed A1 - Posa, Katja A1 - Rührnößl, Alexander A1 - Heinzel, Johannes Christoph A1 - Heimel, Patrick A1 - Mock, Michael A1 - Schädl, Barbara A1 - Keibl, Claudia A1 - Couillard-Despres, Sebastien A1 - Redl, Heinz A1 - Mittermayr, Rainer A1 - Hercher, David T1 - Effects of Extracorporeal Shockwave Therapy on Functional Recovery and Circulating miR-375 and miR-382-5p after Subacute and Chronic Spinal Cord Contusion Injury in Rats JF - Biomedicines N2 - Extracorporeal shockwave therapy (ESWT) can stimulate processes to promote regeneration, including cell proliferation and modulation of inflammation. Specific miRNA expression panels have been established to define correlations with regulatory targets within these pathways. This study aims to investigate the influence of low-energy ESWT-applied within the subacute and chronic phase of SCI (spinal cord injury) on recovery in a rat spinal cord contusion model. Outcomes were evaluated by gait analysis, µCT and histological analysis of spinal cords. A panel of serum-derived miRNAs after SCI and after ESWT was investigated to identify injury-, regeneration- and treatment-associated expression patterns. Rats receiving ESWT showed significant improvement in motor function in both a subacute and a chronic experimental setting. This effect was not reflected in changes in morphology, µCT-parameters or histological markers after ESWT. Expression analysis of various miRNAs, however, revealed changes after SCI and ESWT, with increased miR-375, indicating a neuroprotective effect, and decreased miR-382-5p potentially improving neuroplasticity via its regulatory involvement with BDNF. We were able to demonstrate a functional improvement of ESWT-treated animals after SCI in a subacute and chronic setting. Furthermore, the identification of miR-375 and miR-382-5p could potentially provide new targets for therapeutic intervention in future studies. KW - Tissue Engineering KW - ESWT KW - Spinal Cord Injury Y1 - U6 - http://dx.doi.org/https://doi.org/10.3390/biomedicines10071630 VL - 2022 IS - 10(7) SP - 1630 ER - TY - JOUR A1 - Bernhard, Jonathan C A1 - Marolt Presen, Darja A1 - Li, Ming A1 - Monforte, Xavier A1 - Ferguson, James A1 - Leinfellner, Gabriele A1 - Heimel, Patrick A1 - Betti, Susanne L A1 - Shu, Sharon A1 - Teuschl-Woller, Andreas H A1 - Tangl, Stefan A1 - Redl, Heinz A1 - Vunjak-Novakovic, Gordana T1 - Effects of Endochondral and Intramembranous Ossification Pathways on Bone Tissue Formation and Vascularization in Human Tissue-Engineered Grafts JF - Cells N2 - Bone grafts can be engineered by differentiating human mesenchymal stromal cells (MSCs) via the endochondral and intramembranous ossification pathways. We evaluated the effects of each pathway on the properties of engineered bone grafts and their capacity to drive bone regeneration. Bone-marrow-derived MSCs were differentiated on silk scaffolds into either hypertrophic chondrocytes (hyper) or osteoblasts (osteo) over 5 weeks of in vitro cultivation, and were implanted subcutaneously for 12 weeks. The pathways' constructs were evaluated over time with respect to gene expression, composition, histomorphology, microstructure, vascularization and biomechanics. Hypertrophic chondrocytes expressed higher levels of osteogenic genes and deposited significantly more bone mineral and proteins than the osteoblasts. Before implantation, the mineral in the hyper group was less mature than that in the osteo group. Following 12 weeks of implantation, the hyper group had increased mineral density but a similar overall mineral composition compared with the osteo group. The hyper group also displayed significantly more blood vessel infiltration than the osteo group. Both groups contained M2 macrophages, indicating bone regeneration. These data suggest that, similar to the body's repair processes, endochondral pathway might be more advantageous when regenerating large defects, whereas intramembranous ossification could be utilized to guide the tissue formation pattern with a scaffold architecture. KW - bone tissue engineering KW - endochondral KW - mesenchymal stromal cells KW - ossification KW - intramembranous Y1 - U6 - http://dx.doi.org/10.3390/cells11193070 VL - 11 IS - 19:3070 ER - TY - JOUR A1 - Romanelli, Pasquale A1 - Bieler, Lara A1 - Heimel, Patrick A1 - Škokić, Siniša A1 - Jakubecova, Dominika A1 - Kreutzer, Christina A1 - Zaunmair, Pia A1 - Smolčić, Tomislav A1 - Benedetti, Bruno A1 - Rohde, Eva A1 - Gimona, Mario A1 - Hercher, David A1 - Dobrivojević Radmilović, Marina A1 - Couillard-Despres, Sebastien T1 - Enhancing Functional Recovery Through Intralesional Application of Extracellular Vesicles in a Rat Model of Traumatic Spinal Cord Injury JF - Front Cell Neurosci N2 - Local inflammation plays a pivotal role in the process of secondary damage after spinal cord injury. We recently reported that acute intravenous application of extracellular vesicles (EVs) secreted by human umbilical cord mesenchymal stromal cells dampens the induction of inflammatory processes following traumatic spinal cord injury. However, systemic application of EVs is associated with delayed delivery to the site of injury and the necessity for high doses to reach therapeutic levels locally. To resolve these two constraints, we injected EVs directly at the lesion site acutely after spinal cord injury. We report here that intralesional application of EVs resulted in a more robust improvement of motor recovery, assessed with the BBB score and sub-score, as compared to the intravenous delivery. Moreover, the intralesional application was more potent in reducing inflammation and scarring after spinal cord injury than intravenous administration. Hence, the development of EV-based therapy for spinal cord injury should aim at an early application of vesicles close to the lesion. KW - exosomes KW - inflammation KW - locomotion KW - neuroimaging KW - motor function Y1 - U6 - http://dx.doi.org/10.3389/fncel.2021.795008 VL - 15 ER - TY - JOUR A1 - Feichtinger, Xaver A1 - Heimel, Patrick A1 - Tangl, Stefan A1 - Keibl, Claudia A1 - Nürnberger, Sylvia A1 - Schanda, Jakob Emanuel A1 - Hercher, David A1 - Kocijan, Roland A1 - Redl, Heinz A1 - Grillari, Johannes A1 - Fialka, Christian A1 - Mittermayr, Rainer T1 - Improved biomechanics in experimental chronic rotator cuff repair after shockwaves is not reflected by bone microarchitecture JF - PLoS One KW - chronic rotator cuff repair KW - bone microarchitecture Y1 - U6 - http://dx.doi.org/10.1371/journal.pone.0262294 VL - 17 IS - 1 ER - TY - JOUR A1 - Ahlborn, Felix A1 - Kupka, Friedrich A1 - Weiss, Achim A1 - Flaskamp, Martin T1 - Stellar evolution models with overshooting based on 3-equation non-local theories: II. Main sequence models of A- and B-type stars JF - Astronomy & Astrophysics KW - convection KW - turbulence KW - stars: evolution KW - stars: interiors Y1 - U6 - http://dx.doi.org/https://doi.org/10.1051/0004-6361/202243126 IS - Volume 667 SP - Article Number A97 ER - TY - JOUR A1 - Kupka, Friedrich A1 - Ahlborn, Felix A1 - Weiss, Achim T1 - Stellar evolution models with overshooting based on 3-equation non-local theories: I. Physical basics and the computation of the dissipation rate JF - Astronomy & Astrophysics KW - convection KW - turbulence KW - stars: evolution KW - stars: interiors Y1 - U6 - http://dx.doi.org/https://doi.org/10.1051/0004-6361/202243125 IS - Volume 667 SP - Article Number A96 ER - TY - THES A1 - Tomasch, Janine T1 - Strategies to improve the myogenic outcome of skeletal muscle tissue engineering approaches through optimization of biomaterial properties and mechanical stimuli KW - muscle KW - bioreactor KW - tissue engineering KW - fibrin KW - biomaterial Y1 - ER - TY - GEN A1 - Kupka, Friedrich T1 - Requirements from WP123200 KW - astrophysics Y1 - ER - TY - GEN A1 - Langer, Sarah A1 - Nemec, Iris A1 - Kollmitzer, Josef A1 - Scherer, Matthias A1 - Martinek, Johannes T1 - Vergleich des decompositionierten und des überlagerten Elektromyogramms zur Analyse der Muskelermüdung N2 - Ziel dieser Studie war das überlagerte Elektromyogramm (ueEMG) und das decompositionierte (dEMG) auf deren Reliabilität und Aussagekraft zu überprüfen. Hierfür vollzogen zehn gesunde männliche Probanden zu drei Testzeitpunkten isometrische Ermüdungsmessungen. Hintergrund Bei der Messung des ueEMG werden die Motor Units Aktionspotentiale (MUAPS) elektrisch überlagert. Physiologische Muskelermüdung zeigt sich hier unter anderem in der Veränderung des Frequenzspektrums und der Signalamplitude. Letzteres steigt bei Ermüdung an, wohingegen die mediane Frequenz (MF) sinkt. Eine weitere Möglichkeit die Muskelermüdung mittels Oberflächen-EMG zu ermitteln ist die Anwendung des dEMGs. Dieses ermöglicht mithilfe einer Mustererkennungssoftware einzelne MUAPS zu erkennen. Studien zeigten, dass aktive Motor Units (MU) bei wiederholten oder anhaltenden submaximalen Kontraktionen als Muskelermüdung ihre Feuerungsrate erhöhen und neue MU rekrutiert werden. Bisher wurden diese Methoden jeweils einzeln betrachtet. Um sicherzustellen welcher Ansatz für klinische Daten geeigneter ist, wurden Datensätze zu beiden Methoden gleichzeitig generiert und hinsichtlich ihrer Aussagekraft und Wiederholbarkeit mit statistischen Mitteln verglichen. KW - Elektromyogramm KW - Rehabilitationstechnik Y1 - 2022 ER - TY - GEN A1 - Kupka, Friedrich T1 - Numerical Simulation of A-type and White Dwarf Stars KW - astrophysics Y1 - ER -